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Domain combination pairs in Mycoplasma mycoides subsp. mycoides SC str. Gladysdale

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

225 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 105
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 65
HAD-like Calcium ATPase, transmembrane domain M 54
Actin-like ATPase domain Actin-like ATPase domain 52
P-loop containing nucleoside triphosphate hydrolases Translation proteins 54
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 43
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 42
Homeodomain-like SIS domain 41
Calcium ATPase, transduction domain A HAD-like 43
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 43
Class II aaRS and biotin synthetases Class II aaRS ABD-related 43
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 32
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
Translation proteins EF-G C-terminal domain-like 32
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 32
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 32
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 31
Alpha-L RNA-binding motif Pseudouridine synthase 31
EF-G C-terminal domain-like EF-G C-terminal domain-like 32
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 32
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 31
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 31
MetI-like MetI-like 33
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 31
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 22
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 21
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 21
Class II aaRS and biotin synthetases ThrRS/AlaRS common domain 22
L30e-like alpha/beta knot 21
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 22
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 21
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 21
tRNA-binding arm Class II aaRS and biotin synthetases 21
Nucleic acid-binding proteins Nucleic acid-binding proteins 22
Nucleic acid-binding proteins Translation proteins SH3-like domain 22
Nucleic acid-binding proteins RuvA domain 2-like 22
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 22
(Trans)glycosidases Glycosyl hydrolase domain 22
Class II aaRS and biotin synthetases SufE/NifU 21
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 21
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 21
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 11
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
Galactose mutarotase-like (Trans)glycosidases 11
HD-domain/PDEase-like TGS-like 11
TGS-like ThrRS/AlaRS common domain 11
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
MetI-like Periplasmic binding protein-like II 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
PIN domain-like DNA/RNA polymerases 11
Galactose mutarotase-like Glycosyl hydrolase domain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
Single hybrid motif FAD/NAD(P)-binding domain 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
PUA domain-like Ribosomal protein S5 domain 2-like 11
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 11
DNA/RNA polymerases Lesion bypass DNA polymerase (Y-family), little finger domain 11
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 11
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Glycoside hydrolase/deacetylase Galactose mutarotase-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
Nucleotidyltransferase ACT-like 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
Thiamin pyrophosphokinase, catalytic domain Thiamin pyrophosphokinase, substrate-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases S-adenosyl-L-methionine-dependent methyltransferases 11
Homeodomain-like Homeodomain-like 11
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 11
DNA clamp DNA clamp 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 11
HprK N-terminal domain-like PEP carboxykinase-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
RuvA domain 2-like BRCT domain 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
TGS-like Class II aaRS ABD-related 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Formyltransferase FMT C-terminal domain-like 11
PK beta-barrel domain-like PK C-terminal domain-like 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Nucleic acid-binding proteins HD-domain/PDEase-like 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Ribonuclease H-like DNA/RNA polymerases 11
(Trans)glycosidases Cyclophilin-like 11
Trigger factor ribosome-binding domain FKBP-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 11
Glycoside hydrolase/deacetylase Families 57/38 glycoside transferase middle domain 11
RNase III domain-like dsRNA-binding domain-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
Phoshotransferase/anion transport protein PTS system IIB component-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
MgtE N-terminal domain-like MgtE membrane domain-like 11
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 11
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
TGS-like ACT-like 11
Single hybrid motif CoA-dependent acyltransferases 11
Ribosomal protein L6 Ribosomal protein L6 11
Nucleic acid-binding proteins PheT/TilS domain 11
L9 N-domain-like Ribonuclease H-like 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 11
HD-domain/PDEase-like ACT-like 11
Zinc beta-ribbon DNA primase core 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
FKBP-like Triger factor/SurA peptide-binding domain-like 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase tRNA-binding arm 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
PheT/TilS domain Putative DNA-binding domain 11
TGS-like Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Nucleotidyltransferase TGS-like 11
Nucleotidylyl transferase HD-domain/PDEase-like 11
THUMP domain-like Adenine nucleotide alpha hydrolases-like 11
GreA transcript cleavage protein, N-terminal domain FKBP-like 11
Translation proteins Translation proteins 11
P-loop containing nucleoside triphosphate hydrolases Glucocorticoid receptor-like (DNA-binding domain) 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
Class II aaRS and biotin synthetases Translation proteins 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
PIN domain-like Ribonuclease H-like 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Translation proteins PRC-barrel domain 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
P-loop containing nucleoside triphosphate hydrolases Restriction endonuclease-like 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
MgtE N-terminal domain-like CBS-domain pair 11
Chaperone J-domain HSP40/DnaJ peptide-binding domain 11
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain Alkaline phosphatase-like 11
YhbC-like, N-terminal domain YhbC-like, C-terminal domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 11
Families 57/38 glycoside transferase middle domain Galactose mutarotase-like 11
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 11
Enolase N-terminal domain-like Enolase C-terminal domain-like 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
"Winged helix" DNA-binding domain GAF domain-like 11
Translation proteins Ribosomal protein S5 domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
Nucleic acid-binding proteins GAD domain-like 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
Single hybrid motif FAD/NAD-linked reductases, dimerisation (C-terminal) domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 11
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Peptide methionine sulfoxide reductase Mss4-like 11
Phospholipase D/nuclease Phospholipase D/nuclease 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
Hsp33 domain HSP33 redox switch-like 11
Translation proteins ThrRS/AlaRS common domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 11
CBS-domain pair MgtE membrane domain-like 11
Nucleic acid-binding proteins BRCT domain 11
HD-domain/PDEase-like Nucleotidyltransferase 11

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