Domain combination pairs in Mimulus guttatus v140

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Domain combination pairs

1364 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N)	Superfamily (C)	Number of occurrances	Number unique
P-loop containing nucleoside triphosphate hydrolases	L domain-like	261	17
L domain-like	Protein kinase-like (PK-like)	220	37
F-box domain	RNI-like	204	10
P-loop containing nucleoside triphosphate hydrolases	P-loop containing nucleoside triphosphate hydrolases	168	50
L domain-like	L domain-like	112	37
TRAF domain-like	TRAF domain-like	103	4
RNI-like	L domain-like	96	37
RNA-binding domain, RBD	RNA-binding domain, RBD	96	22
Actin-like ATPase domain	Actin-like ATPase domain	67	16
TPR-like	TPR-like	62	25
RNI-like	Protein kinase-like (PK-like)	58	21
F-box domain	Galactose oxidase, central domain	57	3
Calcium ATPase, transduction domain A	Calcium ATPase, transmembrane domain M	53	14
S-adenosyl-L-methionine-dependent methyltransferases	S-adenosyl-L-methionine-dependent methyltransferases	53	5
GroES-like	NAD(P)-binding Rossmann-fold domains	52	4
Terpenoid cyclases/Protein prenyltransferases	Terpenoid synthases	51	2
alpha-D-mannose-specific plant lectins	Protein kinase-like (PK-like)	48	7
Plant invertase/pectin methylesterase inhibitor	Pectin lyase-like	47	3
RING/U-box	RING/U-box	46	19
HAD-like	Calcium ATPase, transmembrane domain M	46	14
ARM repeat	ARM repeat	45	27
RING/U-box	ARM repeat	45	10
Calcium ATPase, transduction domain A	HAD-like	45	13
Cupredoxins	Cupredoxins	44	5
ABC transporter transmembrane region	P-loop containing nucleoside triphosphate hydrolases	44	10
CRAL/TRIO N-terminal domain	CRAL/TRIO domain	42	7
P-loop containing nucleoside triphosphate hydrolases	RNI-like	42	9
Galactose-binding domain-like	(Trans)glycosidases	41	11
Multidrug resistance efflux transporter EmrE	Multidrug resistance efflux transporter EmrE	40	6
Cyclin-like	Cyclin-like	40	7
Periplasmic binding protein-like I	Periplasmic binding protein-like II	39	4
Barwin-like endoglucanases	PHL pollen allergen	37	1
Thioredoxin-like	GST C-terminal domain-like	37	5
Metal cation-transporting ATPase, ATP-binding domain N	Calcium ATPase, transmembrane domain M	37	8
ABC transporter transmembrane region	ABC transporter transmembrane region	36	5
FAD/NAD(P)-binding domain	FAD-linked reductases, C-terminal domain	36	8
Thiolase-like	Thiolase-like	36	3
Calcium ATPase, transduction domain A	Metal cation-transporting ATPase, ATP-binding domain N	36	7
Riboflavin synthase domain-like	Ferredoxin reductase-like, C-terminal NADP-linked domain	34	10
(Trans)glycosidases	Beta-D-glucan exohydrolase, C-terminal domain	34	3
Protein kinase-like (PK-like)	EF-hand	34	3
F-box domain	L domain-like	33	5
FAD/NAD(P)-binding domain	FAD/NAD(P)-binding domain	33	7
P-loop containing nucleoside triphosphate hydrolases	Translation proteins	31	11
NAD(P)-binding Rossmann-fold domains	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	31	8
Metal cation-transporting ATPase, ATP-binding domain N	HAD-like	30	8
Cysteine-rich domain	Cysteine-rich domain	29	10
CCCH zinc finger	CCCH zinc finger	28	17
Terpenoid cyclases/Protein prenyltransferases	Terpenoid cyclases/Protein prenyltransferases	28	3
C2 domain (Calcium/lipid-binding domain, CaLB)	C2 domain (Calcium/lipid-binding domain, CaLB)	28	9
ENTH/VHS domain	GAT-like domain	27	4
DNA-binding domain	DNA-binding domain	27	3
beta-beta-alpha zinc fingers	beta-beta-alpha zinc fingers	26	11
Voltage-gated potassium channels	cAMP-binding domain-like	26	3
Ubiquitin-like	Ubiquitin-like	26	9
Homeodomain-like	Bet v1-like	25	7
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), peptide-binding domain	25	10
vWA-like	RING/U-box	24	7
RNI-like	RNI-like	24	12
(Trans)glycosidases	Glycosyl hydrolase domain	24	11
Phospholipase D/nuclease	Phospholipase D/nuclease	24	11
NAD(P)-binding Rossmann-fold domains	6-phosphogluconate dehydrogenase C-terminal domain-like	24	7
Galactose-binding domain-like	Galactose-binding domain-like	23	3
HSP40/DnaJ peptide-binding domain	HSP40/DnaJ peptide-binding domain	22	9
GroEL equatorial domain-like	GroEL-intermediate domain like	22	5
GroEL equatorial domain-like	GroEL apical domain-like	22	5
Homeodomain-like	Homeodomain-like	22	10
GroEL-intermediate domain like	GroEL apical domain-like	22	5
Concanavalin A-like lectins/glucanases	Protein kinase-like (PK-like)	22	5
F-box domain	Kelch motif	22	4
Nucleotidyltransferase	PAP/OAS1 substrate-binding domain	21	6
ACT-like	ACT-like	21	11
Actin-like ATPase domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	21	6
Bet v1-like	Bet v1-like	20	6
Ypt/Rab-GAP domain of gyp1p	Ypt/Rab-GAP domain of gyp1p	20	3
PGBD-like	Metalloproteases ("zincins"), catalytic domain	20	2
Heat shock protein 70kD (HSP70), peptide-binding domain	Heat shock protein 70kD (HSP70), C-terminal subdomain	20	5
Tubulin nucleotide-binding domain-like	Tubulin C-terminal domain-like	20	3
Ankyrin repeat	P-loop containing nucleoside triphosphate hydrolases	19	4
Aminoacid dehydrogenase-like, N-terminal domain	NAD(P)-binding Rossmann-fold domains	19	4
Homodimeric domain of signal transducing histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	19	7
Nucleotidylyl transferase	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	18	12
Subtilisin-like	PA domain	18	4
C2 domain (Calcium/lipid-binding domain, CaLB)	Phospholipase D/nuclease	18	6
UBA-like	Ubiquitin-like	18	10
Eukaryotic type KH-domain (KH-domain type I)	Eukaryotic type KH-domain (KH-domain type I)	17	11
PK beta-barrel domain-like	Phosphoenolpyruvate/pyruvate domain	17	4
Chaperone J-domain	HSP40/DnaJ peptide-binding domain	17	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	CheY-like	17	5
Nucleic acid-binding proteins	Nucleic acid-binding proteins	17	14
Thiamin diphosphate-binding fold (THDP-binding)	Thiamin diphosphate-binding fold (THDP-binding)	16	5
P-loop containing nucleoside triphosphate hydrolases	FtsH protease domain-like	16	2
Purple acid phosphatase, N-terminal domain	Metallo-dependent phosphatases	16	3
WD40 repeat-like	WD40 repeat-like	16	7
Thioredoxin-like	Thioredoxin-like	16	10
DNA-binding pseudobarrel domain	DNA-binding pseudobarrel domain	16	4
Adenine nucleotide alpha hydrolases-like	Protein kinase-like (PK-like)	15	4
PK beta-barrel domain-like	PK C-terminal domain-like	15	3
Phosphoenolpyruvate/pyruvate domain	PK C-terminal domain-like	15	3
Homodimeric domain of signal transducing histidine kinase	CheY-like	15	5
Glucocorticoid receptor-like (DNA-binding domain)	Glucocorticoid receptor-like (DNA-binding domain)	15	5
Thiamin diphosphate-binding fold (THDP-binding)	TK C-terminal domain-like	14	3
GroES-like	GroES-like	14	2
PAZ domain	Ribonuclease H-like	14	4
Formate/glycerate dehydrogenase catalytic domain-like	NAD(P)-binding Rossmann-fold domains	14	6
POZ domain	Skp1 dimerisation domain-like	14	2
CheY-like	Homeodomain-like	13	3
DNA-binding pseudobarrel domain	CAD & PB1 domains	13	4
dsRNA-binding domain-like	dsRNA-binding domain-like	13	8
P-loop containing nucleoside triphosphate hydrolases	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	13	2
FAS1 domain	FAS1 domain	13	5
Single hybrid motif	CoA-dependent acyltransferases	13	6
Translation proteins	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	13	2
Nucleic acid-binding proteins	P-loop containing nucleoside triphosphate hydrolases	13	5
ARM repeat	Protein kinase-like (PK-like)	13	13
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Ribosomal protein S5 domain 2-like	13	7
WRKY DNA-binding domain	WRKY DNA-binding domain	12	2
Thioesterase/thiol ester dehydrase-isomerase	Thioesterase/thiol ester dehydrase-isomerase	12	3
UDP-Glycosyltransferase/glycogen phosphorylase	HAD-like	12	3
Galactose-binding domain-like	Galactose mutarotase-like	12	3
Ribosomal protein S5 domain 2-like	GHMP Kinase, C-terminal domain	12	3
DnaJ/Hsp40 cysteine-rich domain	HSP40/DnaJ peptide-binding domain	12	6
Starch-binding domain-like	Galactose-binding domain-like	12	3
LuxS/MPP-like metallohydrolase	LuxS/MPP-like metallohydrolase	12	4
P-loop containing nucleoside triphosphate hydrolases	post-AAA+ oligomerization domain-like	11	4
EF-G C-terminal domain-like	EF-G C-terminal domain-like	11	7
CCCH zinc finger	RNA-binding domain, RBD	11	4
SNARE-like	SNARE fusion complex	11	2
"Winged helix" DNA-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	11	1
POZ domain	TRAF domain-like	11	3
CBS-domain pair	CBS-domain pair	11	7
Galactose mutarotase-like	Starch-binding domain-like	11	2
FYVE/PHD zinc finger	FYVE/PHD zinc finger	11	6
P-loop containing nucleoside triphosphate hydrolases	EF-G C-terminal domain-like	11	7
HMA, heavy metal-associated domain	HMA, heavy metal-associated domain	11	5
RING/U-box	Nucleotide-diphospho-sugar transferases	11	3
FAD/NAD(P)-binding domain	FAD/NAD-linked reductases, dimerisation (C-terminal) domain	11	4
Glucocorticoid receptor-like (DNA-binding domain)	AN1-like Zinc finger	11	1
Lipase/lipooxygenase domain (PLAT/LH2 domain)	Lipoxigenase	11	2
Nucleic acid-binding proteins	Class II aaRS and biotin synthetases	11	5
Zn-dependent exopeptidases	Bacterial exopeptidase dimerisation domain	11	3
EF-hand	EF-hand	11	6
Double Clp-N motif	P-loop containing nucleoside triphosphate hydrolases	10	7
ARM repeat	WD40 repeat-like	10	6
UBA-like	UBA-like	10	6
TPR-like	Protein kinase-like (PK-like)	10	3
P-loop containing nucleoside triphosphate hydrolases	RING/U-box	10	6
Class II aaRS and biotin synthetases	Class II aaRS ABD-related	10	8
Translation proteins	EF-G C-terminal domain-like	10	6
RING/U-box	Protein kinase-like (PK-like)	10	4
PIN domain-like	5' to 3' exonuclease, C-terminal subdomain	10	5
Zn-finger domain of Sec23/24	beta-sandwich domain of Sec23/24	9	5
Cullin repeat-like	Cullin homology domain	9	3
vWA-like	beta-sandwich domain of Sec23/24	9	5
Galactose mutarotase-like	(Trans)glycosidases	9	5
RNA-binding domain, RBD	Retrovirus zinc finger-like domains	9	4
FAD-binding/transporter-associated domain-like	FAD-linked oxidases, C-terminal domain	9	2
Cullin homology domain	"Winged helix" DNA-binding domain	9	3
HCP-like	TPR-like	9	7
P-loop containing nucleoside triphosphate hydrolases	TPR-like	9	4
SET domain	RuBisCo LSMT C-terminal, substrate-binding domain	9	3
Ribosomal protein S5 domain 2-like	Ribonuclease PH domain 2-like	9	3
Zn-finger domain of Sec23/24	Helical domain of Sec23/24	9	5
FYVE/PHD zinc finger	Acyl-CoA N-acyltransferases (Nat)	9	5
t-snare proteins	SNARE fusion complex	9	2
beta-sandwich domain of Sec23/24	Helical domain of Sec23/24	9	5
PDZ domain-like	ClpP/crotonase	9	3
P-loop containing nucleoside triphosphate hydrolases	Ribosomal protein S5 domain 2-like	9	6
Chaperone J-domain	DnaJ/Hsp40 cysteine-rich domain	9	4
Zn-finger domain of Sec23/24	vWA-like	9	5
vWA-like	Helical domain of Sec23/24	9	5
NTF2-like	RNA-binding domain, RBD	9	2
FYVE/PHD zinc finger	RING/U-box	9	8
Ran binding protein zinc finger-like	Ran binding protein zinc finger-like	9	6
Sigma3 and sigma4 domains of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	9	2
Trypsin-like serine proteases	PDZ domain-like	9	4
NAD(P)-binding Rossmann-fold domains	LDH C-terminal domain-like	9	2
F-box domain	Tubby C-terminal domain-like	9	3
YhbY-like	YhbY-like	9	5
Clc chloride channel	CBS-domain pair	9	4
Protein kinase-like (PK-like)	Ankyrin repeat	9	2
Ribonuclease H-like	DNA/RNA polymerases	8	3
Voltage-gated potassium channels	Ankyrin repeat	8	2
EF-hand	Riboflavin synthase domain-like	8	2
RNase III domain-like	dsRNA-binding domain-like	8	7
EF-hand	Ferredoxin reductase-like, C-terminal NADP-linked domain	8	2
WD40 repeat-like	Quinoprotein alcohol dehydrogenase-like	8	6
RING/U-box	TRAF domain-like	8	2
Arabinanase/levansucrase/invertase	Concanavalin A-like lectins/glucanases	8	2
Ribosomal protein S5 domain 2-like	HSP90 C-terminal domain	8	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	SAICAR synthase-like	8	6
P-loop containing nucleoside triphosphate hydrolases	dsRNA-binding domain-like	8	6
ISP domain	Bet v1-like	8	3
E set domains	P-loop containing nucleoside triphosphate hydrolases	8	2
Ankyrin repeat	RING/U-box	8	3
HMA, heavy metal-associated domain	HAD-like	8	6
"Winged helix" DNA-binding domain	"Winged helix" DNA-binding domain	8	5
Single hybrid motif	Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	8	4
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, first 3 domains	8	5
EF-hand	RING/U-box	8	2
F-box domain	WD40 repeat-like	8	5
Sigma2 domain of RNA polymerase sigma factors	Sigma3 and sigma4 domains of RNA polymerase sigma factors	8	1
cAMP-binding domain-like	Ankyrin repeat	8	2
Thiamin diphosphate-binding fold (THDP-binding)	DHS-like NAD/FAD-binding domain	8	2
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex	CoA-dependent acyltransferases	8	4
HMA, heavy metal-associated domain	Calcium ATPase, transduction domain A	8	6
BRCT domain	BRCT domain	8	7
Cullin repeat-like	"Winged helix" DNA-binding domain	8	2
GAF domain-like	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	8	4
HCP-like	HCP-like	8	6
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	HSP90 C-terminal domain	8	2
P-loop containing nucleoside triphosphate hydrolases	EF-hand	7	3
Nucleotidylyl transferase	Nucleotidylyl transferase	7	2
Protein kinase-like (PK-like)	Protein kinase-like (PK-like)	7	4
Zn-finger domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
RING/U-box	WD40 repeat-like	7	6
Helical domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
PreATP-grasp domain	Glutathione synthetase ATP-binding domain-like	7	6
Sec7 domain	ARM repeat	7	5
F-box domain	NHL repeat	7	2
MurD-like peptide ligases, catalytic domain	MurD-like peptide ligases, peptide-binding domain	7	6
E set domains	(Trans)glycosidases	7	4
Nucleotide-diphospho-sugar transferases	Trimeric LpxA-like enzymes	7	2
alpha-D-mannose-specific plant lectins	alpha-D-mannose-specific plant lectins	7	4
beta-sandwich domain of Sec23/24	C-terminal, gelsolin-like domain of Sec23/24	7	3
Ribosomal protein L6	Ribosomal protein L6	7	2
PAP/OAS1 substrate-binding domain	PAP/Archaeal CCA-adding enzyme, C-terminal domain	7	2
Protease propeptides/inhibitors	Subtilisin-like	7	3
HMA, heavy metal-associated domain	Calcium ATPase, transmembrane domain M	7	5
TRAF domain-like	Cysteine proteinases	7	2
Cation efflux protein transmembrane domain-like	Cation efflux protein cytoplasmic domain-like	7	4
Peptidase/esterase 'gauge' domain	alpha/beta-Hydrolases	7	2
ValRS/IleRS/LeuRS editing domain	Nucleotidylyl transferase	7	5
RNA-binding domain, RBD	PABC (PABP) domain	7	4
Nucleotidyltransferase	PAP/Archaeal CCA-adding enzyme, C-terminal domain	7	2
Zinc hairpin stack	RING/U-box	7	2
PUA domain-like	SET domain	7	2
CHY zinc finger-like	Zinc hairpin stack	7	2
ARM repeat	Clathrin adaptor appendage domain	7	4
Cdc48 domain 2-like	P-loop containing nucleoside triphosphate hydrolases	7	4
RCC1/BLIP-II	FYVE/PHD zinc finger	7	2
Galactose oxidase, central domain	E set domains	7	2
SNARE-like	Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor	7	2
TPR-like	Thioredoxin-like	7	5
PLP-dependent transferases	PLP-dependent transferases	7	3
ValRS/IleRS/LeuRS editing domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	7	5
CAD & PB1 domains	Protein kinase-like (PK-like)	7	1
CHY zinc finger-like	RING/U-box	7	2
E set domains	Glycosyl hydrolase domain	7	4
vWA-like	C-terminal, gelsolin-like domain of Sec23/24	7	3
EF-hand	PLC-like phosphodiesterases	6	2
N-terminal domain of alpha and beta subunits of F1 ATP synthase	C-terminal domain of alpha and beta subunits of F1 ATP synthase	6	3
ADC-like	Cdc48 domain 2-like	6	3
E set domains	Ankyrin repeat	6	1
MFS general substrate transporter	MFS general substrate transporter	6	2
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	Zinc-binding domain of translation initiation factor 2 beta	6	2
EF-hand	C2 domain (Calcium/lipid-binding domain, CaLB)	6	2
FKBP-like	FKBP-like	6	3
Calponin-homology domain, CH-domain	P-loop containing nucleoside triphosphate hydrolases	6	3
GST C-terminal domain-like	eEF-1beta-like	6	1
GroEL apical domain-like	SAICAR synthase-like	6	2
Galactose mutarotase-like	Glycosyl hydrolase domain	6	3
PH domain-like	RCC1/BLIP-II	6	1
Zinc beta-ribbon	Cyclin-like	6	3
Homeodomain-like	"Winged helix" DNA-binding domain	6	2
PH domain-like	FYVE/PHD zinc finger	6	1
Acyl-CoA dehydrogenase NM domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	6	5
UBA-like	XPC-binding domain	6	3
FKBP-like	TPR-like	6	3
ADC-like	P-loop containing nucleoside triphosphate hydrolases	6	3
Chromo domain-like	Chromo domain-like	6	5
FYVE/PHD zinc finger	P-loop containing nucleoside triphosphate hydrolases	6	6
DNA clamp	DNA clamp	6	1
Thioredoxin-like	Ubiquitin-like	6	3
Translation proteins	Initiation factor IF2/eIF5b, domain 3	6	2
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain	6	4
RmlC-like cupins	RmlC-like cupins	6	2
HAD-like	Glycerol-3-phosphate (1)-acyltransferase	6	1
N-terminal domain of alpha and beta subunits of F1 ATP synthase	P-loop containing nucleoside triphosphate hydrolases	6	3
GAF domain-like	Homodimeric domain of signal transducing histidine kinase	6	5
RNase III domain-like	RNase III domain-like	6	6
Translation proteins	Ribosomal protein S5 domain 2-like	6	4
P-loop containing nucleoside triphosphate hydrolases	Smc hinge domain	6	2
EF-G C-terminal domain-like	Ribosomal protein S5 domain 2-like	6	4
Translation proteins SH3-like domain	Nucleic acid-binding proteins	6	4
ArfGap/RecO-like zinc finger	C2 domain (Calcium/lipid-binding domain, CaLB)	6	2
P-loop containing nucleoside triphosphate hydrolases	C-terminal domain of alpha and beta subunits of F1 ATP synthase	6	3
Ubiquitin-like	XPC-binding domain	6	3
Protein kinase-like (PK-like)	WD40 repeat-like	6	5
P-loop containing nucleoside triphosphate hydrolases	Initiation factor IF2/eIF5b, domain 3	6	2
DNA repair protein MutS, domain III	P-loop containing nucleoside triphosphate hydrolases	6	4
Domain of the SRP/SRP receptor G-proteins	P-loop containing nucleoside triphosphate hydrolases	6	3
ARM repeat	P-loop containing nucleoside triphosphate hydrolases	6	4
PLC-like phosphodiesterases	C2 domain (Calcium/lipid-binding domain, CaLB)	6	2
FYVE/PHD zinc finger	SET domain	6	4
FYVE/PHD zinc finger	Homeodomain-like	6	4
Ribosomal protein L7/12, oligomerisation (N-terminal) domain	ClpS-like	6	1
PYP-like sensor domain (PAS domain)	PYP-like sensor domain (PAS domain)	6	3
Cryptochrome/photolyase, N-terminal domain	Cryptochrome/photolyase FAD-binding domain	6	3
(Phosphotyrosine protein) phosphatases II	C2 domain (Calcium/lipid-binding domain, CaLB)	6	4
Glutamine synthetase, N-terminal domain	Glutamine synthetase/guanido kinase	6	3
Glutathione synthetase ATP-binding domain-like	Succinyl-CoA synthetase domains	5	1
Amine oxidase N-terminal region	Amine oxidase catalytic domain	5	2
Actin depolymerizing proteins	Actin depolymerizing proteins	5	3
Leukotriene A4 hydrolase N-terminal domain	Metalloproteases ("zincins"), catalytic domain	5	3
Transducin (alpha subunit), insertion domain	P-loop containing nucleoside triphosphate hydrolases	5	1
Amine oxidase N-terminal region	Amine oxidase N-terminal region	5	2
PH domain-like	Oxysterol-binding protein-like	5	2
RCC1/BLIP-II	RCC1/BLIP-II	5	5
P-loop containing nucleoside triphosphate hydrolases	Signal peptide-binding domain	5	2
Cytochrome c	Cytochrome c1 subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase), transmembrane anchor	5	1
S-adenosylmethionine synthetase	S-adenosylmethionine synthetase	5	2
RCC1/BLIP-II	Protein kinase-like (PK-like)	5	4
Enolase N-terminal domain-like	Enolase C-terminal domain-like	5	3
dsRNA-binding domain-like	Ribosomal protein S5 domain 2-like	5	1
TPR-like	HSP20-like chaperones	5	1
Clathrin adaptor appendage domain	Subdomain of clathrin and coatomer appendage domain	5	3
Mannose-binding lectins	Mannose-binding lectins	5	2
YrdC/RibB	RibA-like	5	2
ACT-like	Protein kinase-like (PK-like)	5	2
Phosphoglucomutase, first 3 domains	Phosphoglucomutase, C-terminal domain	5	3
EF-hand	Voltage-gated potassium channels	5	3
"Winged helix" DNA-binding domain	E2F-DP heterodimerization region	5	2
DPP6 N-terminal domain-like	alpha/beta-Hydrolases	5	2
Ribosomal L11/L12e N-terminal domain	Ribosomal protein L11, C-terminal domain	5	2
L9 N-domain-like	Ribosomal protein L9 C-domain	5	1
Acid proteases	Saposin	5	1
Transcription factor IIA (TFIIA), alpha-helical domain	Transcription factor IIA (TFIIA), beta-barrel domain	5	2
Chromo domain-like	P-loop containing nucleoside triphosphate hydrolases	5	4
LysM domain	Protein kinase-like (PK-like)	5	1
Concanavalin A-like lectins/glucanases	P-domain of calnexin/calreticulin	5	1
PEP carboxykinase N-terminal domain	PEP carboxykinase-like	5	1
P-loop containing nucleoside triphosphate hydrolases	"Winged helix" DNA-binding domain	5	4
beta-N-acetylhexosaminidase-like domain	(Trans)glycosidases	5	2
P-loop containing nucleoside triphosphate hydrolases	Sec63 N-terminal domain-like	5	4
P-loop containing nucleoside triphosphate hydrolases	TGS-like	5	3
N-terminal, heterodimerisation domain of RBP7 (RpoE)	Nucleic acid-binding proteins	5	1
PYP-like sensor domain (PAS domain)	GAF domain-like	5	2
DNA ligase/mRNA capping enzyme, catalytic domain	Nucleic acid-binding proteins	5	4
PYP-like sensor domain (PAS domain)	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	5	2
Glutathione synthetase ATP-binding domain-like	Rudiment single hybrid motif	5	4
P-loop containing nucleoside triphosphate hydrolases	RNase III domain-like	5	5
6-phosphogluconate dehydrogenase C-terminal domain-like	6-phosphogluconate dehydrogenase C-terminal domain-like	5	2
Ubiquitin-like	BAG domain	5	3
BEACH domain	WD40 repeat-like	5	3
HD-domain/PDEase-like	Nucleotidyltransferase	5	4
Retrovirus zinc finger-like domains	Retrovirus zinc finger-like domains	5	4
PreATP-grasp domain	Rudiment single hybrid motif	5	4
Fe,Mn superoxide dismutase (SOD), N-terminal domain	Fe,Mn superoxide dismutase (SOD), C-terminal domain	5	3
ARM repeat	Subdomain of clathrin and coatomer appendage domain	5	3
POZ domain	Ankyrin repeat	5	3
Metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	5	5
GAF domain-like	GAF domain-like	5	2
Sec63 N-terminal domain-like	E set domains	4	2
SWIB/MDM2 domain	SWIB/MDM2 domain	4	2
Glycoside hydrolase/deacetylase	Families 57/38 glycoside transferase middle domain	4	3
Eukaryotic RPB5 N-terminal domain	RPB5-like RNA polymerase subunit	4	1
Ankyrin repeat	Ankyrin repeat	4	2
Chromo domain-like	S-adenosyl-L-methionine-dependent methyltransferases	4	1
NAD(P)-binding Rossmann-fold domains	NAD(P)-binding Rossmann-fold domains	4	3
Homeodomain-like	FAD/NAD(P)-binding domain	4	2
PAH2 domain	PAH2 domain	4	2
DNA repair protein MutS, domain II	P-loop containing nucleoside triphosphate hydrolases	4	2
Ankyrin repeat	TPR-like	4	1
TPR-like	Chaperone J-domain	4	4
Voltage-gated potassium channels	Voltage-gated potassium channels	4	2
Domain of the SRP/SRP receptor G-proteins	Signal peptide-binding domain	4	1
PH domain-like	BEACH domain	4	2
ATP-dependent DNA ligase DNA-binding domain	DNA ligase/mRNA capping enzyme, catalytic domain	4	3
Glycoside hydrolase/deacetylase	Galactose mutarotase-like	4	3
Homeodomain-like	FAD-linked reductases, C-terminal domain	4	2
RING/U-box	Cysteine proteinases	4	4
Actin depolymerizing proteins	VHP, Villin headpiece domain	4	2
Restriction endonuclease-like	RuvA domain 2-like	4	2
Eukaryotic type KH-domain (KH-domain type I)	Nucleic acid-binding proteins	4	3
Ubiquitin-like	Zn-binding ribosomal proteins	4	1
NAD-binding domain of HMG-CoA reductase	Substrate-binding domain of HMG-CoA reductase	4	1
Flavoproteins	Riboflavin synthase domain-like	4	3
POZ domain	TAZ domain	4	2
SWIB/MDM2 domain	Plus3-like	4	3
Homeodomain-like	RING/U-box	4	2
Translation proteins	ThrRS/AlaRS common domain	4	2
UBA-like	Thioredoxin-like	4	2
Acetyl-CoA synthetase-like	ACP-like	4	3
beta-Galactosidase/glucuronidase domain	beta-Galactosidase/glucuronidase domain	4	3
ThrRS/AlaRS common domain	Class II aaRS and biotin synthetases	4	3
Class I glutamine amidotransferase-like	Class I glutamine amidotransferase-like	4	2
PheT/TilS domain	Class II aaRS and biotin synthetases	4	3
Creatinase/prolidase N-terminal domain	Creatinase/aminopeptidase	4	3
Kelch motif	Metallo-dependent phosphatases	4	3
ClpP/crotonase	6-phosphogluconate dehydrogenase C-terminal domain-like	4	1
DNA repair protein MutS, domain II	DNA repair protein MutS, domain III	4	2
ARM repeat	Hect, E3 ligase catalytic domain	4	3
TPR-like	RING/U-box	4	4
NagB/RpiA/CoA transferase-like	D-ribose-5-phosphate isomerase (RpiA), lid domain	4	3
Thioredoxin-like	FAD-dependent thiol oxidase	4	2
ARM repeat	PH domain-like	4	2
BAR/IMD domain-like	SH3-domain	4	1
Translational machinery components	L30e-like	4	2
RING/U-box	RNA-binding domain, RBD	4	2
Rap30/74 interaction domains	"Winged helix" DNA-binding domain	4	2
Ribosomal protein S5 domain 2-like	Ribosomal protein S5 domain 2-like	4	3
PYP-like sensor domain (PAS domain)	Protein kinase-like (PK-like)	4	1
CRAL/TRIO domain	Supernatant protein factor (SPF), C-terminal domain	4	3
Concanavalin A-like lectins/glucanases	BEACH domain	4	2
Acyl-CoA binding protein	Ankyrin repeat	4	1
Coiled-coil domain of nucleotide exchange factor GrpE	Head domain of nucleotide exchange factor GrpE	4	1
Periplasmic binding protein-like II	ACT-like	4	1
Obg GTP-binding protein N-terminal domain	P-loop containing nucleoside triphosphate hydrolases	4	4
Flavoproteins	Ferredoxin reductase-like, C-terminal NADP-linked domain	4	3
PLP-binding barrel	Alanine racemase C-terminal domain-like	4	2
Cysteine proteinases	Granulin repeat	4	2
Concanavalin A-like lectins/glucanases	PH domain-like	4	2
GINS helical bundle-like	PriA/YqbF domain	4	3
PRTase-like	PRTase-like	4	2
PH domain-like	WD40 repeat-like	4	2
TPR-like	CAD & PB1 domains	4	3
ATP-dependent DNA ligase DNA-binding domain	Nucleic acid-binding proteins	4	3
ClpP/crotonase	NAD(P)-binding Rossmann-fold domains	4	1
Concanavalin A-like lectins/glucanases	WD40 repeat-like	4	2
Adenine nucleotide alpha hydrolases-like	Argininosuccinate synthetase, C-terminal domain	4	2
Protein kinase-like (PK-like)	KA1-like	4	1
Protease propeptides/inhibitors	PA domain	4	2
HAD-like	BRCT domain	4	3
"Winged helix" DNA-binding domain	RNA-binding domain, RBD	4	3
ClpP/crotonase	ClpP/crotonase	4	4
Carbamate kinase-like	ALDH-like	4	1
DEK C-terminal domain	SWIB/MDM2 domain	4	2
CBS-domain pair	CAD & PB1 domains	4	1
(Trans)glycosidases	Ricin B-like lectins	4	1
Putative DNA-binding domain	PheT/TilS domain	4	3
beta-Galactosidase/glucuronidase domain	(Trans)glycosidases	4	3
Families 57/38 glycoside transferase middle domain	Galactose mutarotase-like	4	3
Putative DNA-binding domain	Class II aaRS and biotin synthetases	4	3
Fe-S cluster assembly (FSCA) domain-like	Fe-S cluster assembly (FSCA) domain-like	4	1
DNA repair protein MutS, domain I	P-loop containing nucleoside triphosphate hydrolases	4	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase flavoprotein C-terminal domain-like	3	2
Putative DNA-binding domain	Putative DNA-binding domain	3	2
PUA domain-like	Ribosomal protein S5 domain 2-like	3	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase flavoprotein C-terminal domain-like	3	2
RING/U-box	UBA-like	3	2
PAZ domain	RNase III domain-like	3	3
BAR/IMD domain-like	ArfGap/RecO-like zinc finger	3	2
Methionyl-tRNA synthetase (MetRS), Zn-domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	3	3
PH domain-like	Ankyrin repeat	3	2
DNA repair protein MutS, domain I	DNA repair protein MutS, domain III	3	1
E set domains	AMPKBI-like	3	1
CCCH zinc finger	HIT-like	3	1
Ubiquitin-like	Cysteine proteinases	3	2
L30e-like	alpha/beta knot	3	1
NAD(P)-binding Rossmann-fold domains	Aldolase	3	2
CRAL/TRIO N-terminal domain	Supernatant protein factor (SPF), C-terminal domain	3	2
P-loop containing nucleoside triphosphate hydrolases	RNA-binding domain, RBD	3	2
Prokaryotic type KH domain (KH-domain type II)	Ribosomal protein S3 C-terminal domain	3	1
CO dehydrogenase flavoprotein C-terminal domain-like	Molybdenum cofactor-binding domain	3	2
Hypothetical protein SAV1430	Fe-S cluster assembly (FSCA) domain-like	3	2
WW domain	P-loop containing nucleoside triphosphate hydrolases	3	2
WD40 repeat-like	SNARE fusion complex	3	3
P-loop containing nucleoside triphosphate hydrolases	Homeodomain-like	3	2
Dimeric alpha+beta barrel	Dimeric alpha+beta barrel	3	1
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	3	2
Adenine nucleotide alpha hydrolases-like	RING/U-box	3	1
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	3	1
F-box domain	HCP-like	3	3
Galactose-binding domain-like	NAD(P)-binding Rossmann-fold domains	3	2
P-loop containing nucleoside triphosphate hydrolases	CYTH-like phosphatases	3	2
FYVE/PHD zinc finger	GYF domain	3	2
PH domain-like	Bet v1-like	3	2
F-box domain	F-box domain	3	3
RING/U-box	PUA domain-like	3	3
PRP4-like	WD40 repeat-like	3	1
PH domain-like	ArfGap/RecO-like zinc finger	3	2
PLC-like phosphodiesterases	PLC-like phosphodiesterases	3	2
Domain of poly(ADP-ribose) polymerase	ADP-ribosylation	3	3
ALDH-like	ALDH-like	3	1
P-loop containing nucleoside triphosphate hydrolases	PRTase-like	3	1
ARM repeat	POZ domain	3	2
Nucleic acid-binding proteins	"Winged helix" DNA-binding domain	3	2
P-loop containing nucleoside triphosphate hydrolases	Pre-protein crosslinking domain of SecA	3	3
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	L30e-like	3	1
FAD/NAD(P)-binding domain	EF-hand	3	1
PRTase-like	Ribulose-phoshate binding barrel	3	1
RNI-like	ARM repeat	3	1
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1	Translational machinery components	3	1
Protein kinase-like (PK-like)	PP2C-like	3	3
NAD(P)-binding Rossmann-fold domains	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
BAR/IMD domain-like	PH domain-like	3	2
WGR domain-like	ADP-ribosylation	3	3
P-loop containing nucleoside triphosphate hydrolases	RecA protein, C-terminal domain	3	2
FF domain	FF domain	3	3
TAZ domain	FYVE/PHD zinc finger	3	2
DNase I-like	DNase I-like	3	2
Formate/glycerate dehydrogenase catalytic domain-like	Formate/glycerate dehydrogenase catalytic domain-like	3	2
Rhodanese/Cell cycle control phosphatase	Rhodanese/Cell cycle control phosphatase	3	2
Nucleotidylyl transferase	Ribosomal protein L25-like	3	3
(Phosphotyrosine protein) phosphatases II	Formin homology 2 domain (FH2 domain)	3	1
beta-beta-alpha zinc fingers	Ribonuclease H-like	3	2
PH domain-like	HMG-box	3	1
DNA repair protein MutS, domain I	DNA repair protein MutS, domain II	3	1
SNARE fusion complex	SNARE fusion complex	3	1
UROD/MetE-like	UROD/MetE-like	3	1
ARID-like	HMG-box	3	2
NAD(P)-binding Rossmann-fold domains	Citrate synthase	3	1
Class II aaRS ABD-related	C-terminal domain of ProRS	3	2
Adenine nucleotide alpha hydrolases-like	Thioredoxin-like	3	1
TAZ domain	RING/U-box	3	2
Oxidoreductase molybdopterin-binding domain	E set domains	3	2
Toll/Interleukin receptor TIR domain	P-loop containing nucleoside triphosphate hydrolases	3	1
"Winged helix" DNA-binding domain	Sec63 N-terminal domain-like	3	2
ARM repeat	Concanavalin A-like lectins/glucanases	3	1
Calponin-homology domain, CH-domain	EB1 dimerisation domain-like	3	2
FAD-binding/transporter-associated domain-like	CO dehydrogenase molybdoprotein N-domain-like	3	2
PA domain	RING/U-box	3	2
PYP-like sensor domain (PAS domain)	Galactose oxidase, central domain	3	1
WW domain	WW domain	3	3
FAD/NAD(P)-binding domain	Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	3	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleotidylyl transferase	3	3
Zinc-binding domain of translation initiation factor 2 beta	ARM repeat	3	1
NAD(P)-binding Rossmann-fold domains	ACT-like	3	3
CO dehydrogenase ISP C-domain like	Molybdenum cofactor-binding domain	3	2
alpha/beta-Hydrolases	alpha/beta-Hydrolases	3	2
Acyl-CoA dehydrogenase C-terminal domain-like	Acyl-CoA dehydrogenase C-terminal domain-like	3	2
FAD/NAD(P)-binding domain	Thioredoxin-like	3	3
WW domain	FF domain	3	3
C2 domain (Calcium/lipid-binding domain, CaLB)	ARM repeat	3	3
Nucleotidyltransferase	Poly A polymerase C-terminal region-like	3	1
F1F0 ATP synthase subunit C	F1F0 ATP synthase subunit C	3	2
ARM repeat	BEACH domain	3	1
PH domain-like	GTPase activation domain, GAP	3	1
CheY-like	CheY-like	3	2
C2 domain (Calcium/lipid-binding domain, CaLB)	Formin homology 2 domain (FH2 domain)	3	1
P-loop containing nucleoside triphosphate hydrolases	HRDC-like	3	3
FYVE/PHD zinc finger	SAICAR synthase-like	3	1
TATA-box binding protein-like	TATA-box binding protein-like	3	1
Activating enzymes of the ubiquitin-like proteins	Activating enzymes of the ubiquitin-like proteins	3	1
SWIB/MDM2 domain	GYF domain	3	2
Trypsin-like serine proteases	Trypsin-like serine proteases	3	2
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain	3	1
ARM repeat	TPR-like	3	2
2Fe-2S ferredoxin-like	alpha-helical ferredoxin	3	1
RING/U-box	Ran binding protein zinc finger-like	3	1
Plant lectins/antimicrobial peptides	Lysozyme-like	3	1
MOSC N-terminal domain-like	PK beta-barrel domain-like	3	3
PUA domain-like	P-loop containing nucleoside triphosphate hydrolases	3	2
WGR domain-like	Domain of poly(ADP-ribose) polymerase	3	3
Translation initiation factor 2 beta, aIF2beta, N-terminal domain	ARM repeat	3	1
WD40 repeat-like	DNase I-like	3	2
CO dehydrogenase flavoprotein C-terminal domain-like	CO dehydrogenase molybdoprotein N-domain-like	3	2
Thioredoxin-like	"Winged helix" DNA-binding domain	3	1
Galactose-binding domain-like	beta-Galactosidase/glucuronidase domain	3	2
Class II aaRS and biotin synthetases	C-terminal domain of ProRS	3	2
BAR/IMD domain-like	Ankyrin repeat	3	2
NAD(P)-binding Rossmann-fold domains	1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain	3	2
Sec63 N-terminal domain-like	Sec63 N-terminal domain-like	3	2
Chaperone J-domain	4Fe-4S ferredoxins	3	2
Ribosomal L27 protein-like	Nucleic acid-binding proteins	3	2
Calcium-dependent phosphotriesterase	WD40 repeat-like	3	2
6-phosphogluconate dehydrogenase C-terminal domain-like	UDP-glucose/GDP-mannose dehydrogenase C-terminal domain	3	1
FYVE/PHD zinc finger	GroEL apical domain-like	3	1
HAD-like	dsRNA-binding domain-like	3	2
HAD-like	Riboflavin kinase-like	3	1
P-loop containing nucleoside triphosphate hydrolases	Retrovirus zinc finger-like domains	3	2
Nicotinate/Quinolinate PRTase N-terminal domain-like	Nicotinate/Quinolinate PRTase C-terminal domain-like	3	2
ARM repeat	SH3-domain	3	1
Carbamate kinase-like	ACT-like	3	3
Arp2/3 complex subunits	Arp2/3 complex subunits	3	2
CO dehydrogenase ISP C-domain like	CO dehydrogenase molybdoprotein N-domain-like	3	2
P-loop containing nucleoside triphosphate hydrolases	PAZ domain	3	3
Alpha-L RNA-binding motif	Pseudouridine synthase	3	2
DUSP-like	Cysteine proteinases	3	2
PYP-like sensor domain (PAS domain)	F-box domain	3	1
CO dehydrogenase ISP C-domain like	FAD-binding/transporter-associated domain-like	3	2
DNA/RNA polymerases	Lesion bypass DNA polymerase (Y-family), little finger domain	3	2
ISP transmembrane anchor	ISP domain	3	1
ArfGap/RecO-like zinc finger	Ankyrin repeat	3	2
Creatinase/aminopeptidase	"Winged helix" DNA-binding domain	3	2
CCCH zinc finger	Eukaryotic type KH-domain (KH-domain type I)	3	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	Glutamyl tRNA-reductase dimerization domain	3	2
SBT domain	Ankyrin repeat	3	2
CO dehydrogenase molybdoprotein N-domain-like	Molybdenum cofactor-binding domain	3	2
HIT/MYND zinc finger-like	Cysteine proteinases	3	1
Plus3-like	GYF domain	3	2
GAF domain-like	CheY-like	3	2
FAD-binding/transporter-associated domain-like	Molybdenum cofactor-binding domain	3	2
Adenine nucleotide alpha hydrolases-like	Molybdenum cofactor biosynthesis proteins	2	1
Ran binding protein zinc finger-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Ribonuclease PH domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Diaminopimelate epimerase-like	Diaminopimelate epimerase-like	2	1
Acid proteases	Acid proteases	2	2
UBC-like	RING/U-box	2	2
BRCT domain	WGR domain-like	2	2
(Trans)glycosidases	(Trans)glycosidases	2	2
TPR-like	SET domain	2	1
Class II aaRS and biotin synthetases	Translation proteins	2	1
Zn-dependent exopeptidases	Transferrin receptor-like dimerisation domain	2	1
RNA-binding domain, RBD	HCP-like	2	1
FAD/NAD(P)-binding domain	Trimeric LpxA-like enzymes	2	2
Carbamate kinase-like	Acyl-CoA N-acyltransferases (Nat)	2	2
Composite domain of metallo-dependent hydrolases	Composite domain of metallo-dependent hydrolases	2	2
PA domain	Transferrin receptor-like dimerisation domain	2	1
Actin-crosslinking proteins	(Trans)glycosidases	2	1
FYVE/PHD zinc finger	PUA domain-like	2	2
Ribosomal L27 protein-like	Eukaryotic type KH-domain (KH-domain type I)	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FMN-linked oxidoreductases	2	2
alpha/beta-Hydrolases	Glycerol-3-phosphate (1)-acyltransferase	2	1
FMN-linked oxidoreductases	Alpha subunit of glutamate synthase, C-terminal domain	2	2
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Adenine nucleotide alpha hydrolases-like	2	2
Thioredoxin-like	eEF1-gamma domain	2	1
Glutathione synthetase ATP-binding domain-like	Phosphoenolpyruvate/pyruvate domain	2	2
Glutathione synthetase ATP-binding domain-like	Phosphoglycerate mutase-like	2	1
vWA-like	SPOC domain-like	2	2
E set domains	E set domains	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite/Sulfite reductase N-terminal domain-like	2	1
UDP-Glycosyltransferase/glycogen phosphorylase	UDP-Glycosyltransferase/glycogen phosphorylase	2	1
Ribonuclease PH domain 2-like	Nucleic acid-binding proteins	2	2
Tex N-terminal region-like	Nucleic acid-binding proteins	2	2
FAD/NAD(P)-binding domain	Acetyl-CoA synthetase-like	2	2
Ubiquitin-like	TPR-like	2	1
Lipocalins	Lipocalins	2	1
Ubiquitin-like	PUG domain-like	2	2
Dcp2 domain-like	Nudix	2	1
PH domain-like	Phospholipase D/nuclease	2	1
(Phosphotyrosine protein) phosphatases II	E set domains	2	2
Methylglyoxal synthase-like	Cytidine deaminase-like	2	1
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Nucleic acid-binding proteins	2	2
BRCT domain	Domain of poly(ADP-ribose) polymerase	2	2
WD40 repeat-like	Bromodomain	2	1
YjeF N-terminal domain-like	FMN-binding split barrel	2	2
ThrRS/AlaRS common domain	Class II aaRS ABD-related	2	2
Acetyl-CoA synthetase-like	Heme-dependent catalase-like	2	2
Tudor/PWWP/MBT	SET domain	2	2
Acyl-CoA N-acyltransferases (Nat)	Acyl-CoA N-acyltransferases (Nat)	2	1
2Fe-2S ferredoxin-like	CO dehydrogenase molybdoprotein N-domain-like	2	1
Aconitase iron-sulfur domain	LeuD/IlvD-like	2	1
eIF2alpha middle domain-like	eIF-2-alpha, C-terminal domain	2	1
MurE/MurF N-terminal domain	MurD-like peptide ligases, peptide-binding domain	2	2
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	Eukaryotic type KH-domain (KH-domain type I)	2	2
PH domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
BRCT domain	post-AAA+ oligomerization domain-like	2	1
CAD & PB1 domains	UBA-like	2	1
Pre-protein crosslinking domain of SecA	Helical scaffold and wing domains of SecA	2	2
Clavaminate synthase-like	FYVE/PHD zinc finger	2	2
MIT domain	P-loop containing nucleoside triphosphate hydrolases	2	1
LEA14-like	LEA14-like	2	1
Carbon-nitrogen hydrolase	Adenine nucleotide alpha hydrolases-like	2	2
FYVE/PHD zinc finger	Chromo domain-like	2	2
4'-phosphopantetheinyl transferase	4'-phosphopantetheinyl transferase	2	1
Six-hairpin glycosidases	AbfB domain	2	2
P-loop containing nucleoside triphosphate hydrolases	CCCH zinc finger	2	1
Translation initiation factor IF3, N-terminal domain	Translation initiation factor IF3, C-terminal domain	2	2
Leukotriene A4 hydrolase N-terminal domain	ARM repeat	2	2
Ubiquitin-like	L domain-like	2	2
CorA soluble domain-like	Magnesium transport protein CorA, transmembrane region	2	2
Trimeric LpxA-like enzymes	Heme-dependent catalase-like	2	2
F-box domain	Pectin lyase-like	2	1
EF-hand	Mitochondrial carrier	2	1
Tex N-terminal region-like	RuvA domain 2-like	2	2
Glycerol-3-phosphate (1)-acyltransferase	EF-hand	2	1
SMAD/FHA domain	Phospholipase D/nuclease	2	2
Trimeric LpxA-like enzymes	Trimeric LpxA-like enzymes	2	2
Nitrite/Sulfite reductase N-terminal domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
PurM N-terminal domain-like	PurM C-terminal domain-like	2	2
Ubiquitin-like	Cap-Gly domain	2	2
P-loop containing nucleoside triphosphate hydrolases	RuvA domain 2-like	2	1
RNA-binding domain, RBD	Ran binding protein zinc finger-like	2	2
Galactose oxidase, central domain	P-loop containing nucleoside triphosphate hydrolases	2	1
Periplasmic binding protein-like II	GlnB-like	2	1
PreATP-grasp domain	Single hybrid motif	2	2
Ribonuclease H-like	RING/U-box	2	2
Nucleic acid-binding proteins	S-adenosyl-L-methionine-dependent methyltransferases	2	2
P-loop containing nucleoside triphosphate hydrolases	vWA-like	2	2
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	ThrRS/AlaRS common domain	2	1
"Winged helix" DNA-binding domain	E set domains	2	1
Eukaryotic type KH-domain (KH-domain type I)	Retrovirus zinc finger-like domains	2	2
Ribosomal protein S5 domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	2	2
ARID-like	HSP20-like chaperones	2	1
Actin-crosslinking proteins	Actin-crosslinking proteins	2	1
alpha/beta knot	Nucleic acid-binding proteins	2	1
Cysteine proteinases	Calpain large subunit, middle domain (domain III)	2	1
P-loop containing nucleoside triphosphate hydrolases	Helical scaffold and wing domains of SecA	2	2
PapD-like	Ankyrin repeat	2	1
TAZ domain	TAZ domain	2	1
NAD(P)-binding Rossmann-fold domains	Serine metabolism enzymes domain	2	2
DPP6 N-terminal domain-like	WD40 repeat-like	2	2
BRCT domain	ADP-ribosylation	2	2
Chaperone J-domain	E set domains	2	1
Class II aaRS and biotin synthetases	Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	2	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	tRNA-binding arm	2	2
FAD/NAD(P)-binding domain	S-adenosyl-L-methionine-dependent methyltransferases	2	1
Glutamyl tRNA-reductase catalytic, N-terminal domain	NAD(P)-binding Rossmann-fold domains	2	1
POZ domain	Quinoprotein alcohol dehydrogenase-like	2	1
Rad51 N-terminal domain-like	P-loop containing nucleoside triphosphate hydrolases	2	1
Nucleotidyltransferase	TGS-like	2	2
P-loop containing nucleoside triphosphate hydrolases	D-aminoacid aminotransferase-like PLP-dependent enzymes	2	1
Glutathione synthetase ATP-binding domain-like	Single hybrid motif	2	2
Ribonuclease H-like	Ribonuclease H-like	2	2
FAD/NAD(P)-binding domain	Heme-dependent catalase-like	2	2
Chaperone J-domain	Sec63 N-terminal domain-like	2	1
Insert subdomain of RNA polymerase alpha subunit	RBP11-like subunits of RNA polymerase	2	2
Phosphoglycerate mutase-like	Phosphoglycerate mutase-like	2	1
ISP domain	Chlorophyll a-b binding protein	2	1
Ribonuclease PH domain 2-like	Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3	2	2
N-terminal domain of adenylylcyclase associated protein, CAP	C-terminal domain of adenylylcyclase associated protein	2	1
Ribonuclease H-like	HRDC-like	2	2
Translation proteins	Translation proteins	2	1
ACP-like	Trimeric LpxA-like enzymes	2	2
P-loop containing nucleoside triphosphate hydrolases	Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain	2	2
HD-domain/PDEase-like	TGS-like	2	2
Thioredoxin-like	Cysteine proteinases	2	1
C-terminal domain of alpha and beta subunits of F1 ATP synthase	Epsilon subunit of F1F0-ATP synthase N-terminal domain	2	1
HMA, heavy metal-associated domain	Metal cation-transporting ATPase, ATP-binding domain N	2	2
Heme oxygenase-like	HAD-like	2	1
Concanavalin A-like lectins/glucanases	Cysteine proteinases	2	1
Heat shock protein 70kD (HSP70), C-terminal subdomain	Heat shock protein 70kD (HSP70), C-terminal subdomain	2	1
ACP-like	Heme-dependent catalase-like	2	2
FYVE/PHD zinc finger	Plus3-like	2	1
Tryptophan synthase beta subunit-like PLP-dependent enzymes	ACT-like	2	1
Amidase signature (AS) enzymes	TPR-like	2	1
P-loop containing nucleoside triphosphate hydrolases	HAND domain of the nucleosome remodeling ATPase ISWI	2	1
Formate/glycerate dehydrogenase catalytic domain-like	ACT-like	2	2
PA domain	Zn-dependent exopeptidases	2	1
P-loop containing nucleoside triphosphate hydrolases	Prokaryotic type KH domain (KH-domain type II)	2	1
Macro domain-like	CRAL/TRIO domain	2	1
Eukaryotic type KH-domain (KH-domain type I)	RNA-binding domain, RBD	2	2
SMAD/FHA domain	P-loop containing nucleoside triphosphate hydrolases	2	2
FYVE/PHD zinc finger	SWIB/MDM2 domain	2	1
C2 domain (Calcium/lipid-binding domain, CaLB)	vWA-like	2	1
ACP-like	Quinoprotein alcohol dehydrogenase-like	2	1
Starch-binding domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
Ribosomal protein S5 domain 2-like	Nucleic acid-binding proteins	2	2
Retrovirus zinc finger-like domains	DNA/RNA polymerases	2	2
UBC-like	Endosomal sorting complex assembly domain	2	1
Arabinanase/levansucrase/invertase	Nucleotide-diphospho-sugar transferases	2	1
PUA domain-like	S-adenosyl-L-methionine-dependent methyltransferases	2	2
Retrovirus zinc finger-like domains	Plus3-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Macro domain-like	2	2
Acyl-CoA N-acyltransferases (Nat)	Formin homology 2 domain (FH2 domain)	2	1
EF-hand	Sm-like ribonucleoproteins	2	1
NSFL1 (p97 ATPase) cofactor p47, SEP domain	Ubiquitin-like	2	2
RuvA domain 2-like	Nucleic acid-binding proteins	2	2
PAZ domain	dsRNA-binding domain-like	2	2
POZ domain	TPR-like	2	2
Rudiment single hybrid motif	Single hybrid motif	2	2
GST C-terminal domain-like	eEF1-gamma domain	2	1
2Fe-2S ferredoxin-like	CO dehydrogenase ISP C-domain like	2	1
tRNA-binding arm	Class II aaRS and biotin synthetases	2	2
Nucleic acid-binding proteins	eIF2alpha middle domain-like	2	1
Acyl-CoA N-acyltransferases (Nat)	Bromodomain	2	1
The spindle assembly checkpoint protein mad2	"Winged helix" DNA-binding domain	2	1
NAD(P)-binding Rossmann-fold domains	Glutamyl tRNA-reductase dimerization domain	2	1
Retrovirus zinc finger-like domains	Acid proteases	2	2
2Fe-2S ferredoxin-like	CO dehydrogenase flavoprotein C-terminal domain-like	2	1
Hypothetical protein c14orf129, hspc210	TPR-like	2	2
Folate-binding domain	Aminomethyltransferase beta-barrel domain	2	2
eIF2alpha middle domain-like	Cysteine proteinases	2	1
Rhomboid-like	UBA-like	2	2
F-box domain	Clavaminate synthase-like	2	2
PDZ domain-like	PDZ domain-like	2	1
Tex N-terminal region-like	Ribonuclease H-like	2	2
Cullin repeat-like	Cullin repeat-like	2	1
SET domain	HIT/MYND zinc finger-like	2	2
P-loop containing nucleoside triphosphate hydrolases	Class I glutamine amidotransferase-like	2	2
"Winged helix" DNA-binding domain	Zinc beta-ribbon	2	1
Mechanosensitive channel protein MscS (YggB), transmembrane region	Sm-like ribonucleoproteins	2	1
Kelch motif	Kelch motif	2	2
2Fe-2S ferredoxin-like	Molybdenum cofactor-binding domain	2	1
Chaperone J-domain	RNA-binding domain, RBD	2	1
Single hybrid motif	Single hybrid motif	2	1
Acetyl-CoA synthetase-like	Quinoprotein alcohol dehydrogenase-like	2	1
PUA domain-like	Nucleotidylyl transferase	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	PRTase-like	2	1
Tetrahydrobiopterin biosynthesis enzymes-like	Tetrahydrobiopterin biosynthesis enzymes-like	2	1
2Fe-2S ferredoxin-like	4Fe-4S ferredoxins	2	1
(Trans)glycosidases	Chitinase insertion domain	2	2
P-loop containing nucleoside triphosphate hydrolases	Bromodomain	2	2
Clathrin heavy-chain terminal domain	ARM repeat	2	2
DNase I-like	EF-hand	2	1
Ribosomal protein S5 domain 2-like	Eukaryotic type KH-domain (KH-domain type I)	2	2
Cyclophilin-like	TPR-like	2	1
S-adenosyl-L-methionine-dependent methyltransferases	PLP-dependent transferases	2	1
Ribosomal protein S5 domain 2-like	Type II DNA topoisomerase	2	2
Ran binding protein zinc finger-like	EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain	2	1
Protein kinase-like (PK-like)	PH domain-like	2	2
Glutathione synthetase ATP-binding domain-like	Glutathione synthetase ATP-binding domain-like	2	2
Nucleotidylyl transferase	tRNA-binding arm	2	2
RuvA domain 2-like	RuvA domain 2-like	2	2
MurE/MurF N-terminal domain	MurD-like peptide ligases, catalytic domain	2	2
Ran binding protein zinc finger-like	Translation proteins	2	1
Ribonuclease H-like	RuvA domain 2-like	2	2
Tudor/PWWP/MBT	FYVE/PHD zinc finger	2	2
BRCT domain	P-loop containing nucleoside triphosphate hydrolases	2	1
2Fe-2S ferredoxin-like	FAD-binding/transporter-associated domain-like	2	1
UBA-like	Elongation factor Ts (EF-Ts), dimerisation domain	2	2
CCCH zinc finger	RING/U-box	2	2
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase	2	2
Periplasmic binding protein-like II	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain	2	1
ARID-like	FYVE/PHD zinc finger	2	2
PX domain	BAR/IMD domain-like	2	2
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain	Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain	2	1
Nucleic acid-binding proteins	eIF-2-alpha, C-terminal domain	2	1
4Fe-4S ferredoxins	P-loop containing nucleoside triphosphate hydrolases	2	1
Ubiquitin-like	Homeodomain-like	2	1
HMA, heavy metal-associated domain	Cu,Zn superoxide dismutase-like	2	1
Acetyl-CoA synthetase-like	Trimeric LpxA-like enzymes	2	2
F-box domain	HIT/MYND zinc finger-like	2	2
F-box domain	NTF2-like	2	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	Alpha subunit of glutamate synthase, C-terminal domain	2	2
Glutathione synthetase ATP-binding domain-like	Phosphohistidine domain	2	2
EF-hand	Calponin-homology domain, CH-domain	2	2
Aminopeptidase/glucanase lid domain	Zn-dependent exopeptidases	2	1
Serine metabolism enzymes domain	ACT-like	2	2
POZ domain	POZ domain	2	2
Formate/glycerate dehydrogenase catalytic domain-like	Serine metabolism enzymes domain	2	2
FAD/NAD(P)-binding domain	ACP-like	2	2
ARM repeat	"Winged helix" DNA-binding domain	2	1
4Fe-4S ferredoxins	Formate dehydrogenase/DMSO reductase, domains 1-3	2	1
Phosphohistidine domain	Phosphoenolpyruvate/pyruvate domain	2	2
R1 subunit of ribonucleotide reductase, N-terminal domain	PFL-like glycyl radical enzymes	2	1
ENT-like	Tudor/PWWP/MBT	2	2
BRCT domain	FYVE/PHD zinc finger	2	2
HCP-like	SMR domain-like	2	2
(Phosphotyrosine protein) phosphatases II	Actin depolymerizing proteins	2	2
Metalloproteases ("zincins"), catalytic domain	ARM repeat	2	2
P-loop containing nucleoside triphosphate hydrolases	Hypothetical protein YjiA, C-terminal domain	2	2
Nucleotidylyl transferase	An anticodon-binding domain of class I aminoacyl-tRNA synthetases	2	1
TATA-box binding protein-like	DNA-glycosylase	2	2
AN1-like Zinc finger	AN1-like Zinc finger	2	2
UraD-Like	Transthyretin (synonym: prealbumin)	2	1
Fe-S cluster assembly (FSCA) domain-like	P-loop containing nucleoside triphosphate hydrolases	2	2
CAD & PB1 domains	RING/U-box	2	1
UBA-like	PUG domain-like	2	2
HAND domain of the nucleosome remodeling ATPase ISWI	Homeodomain-like	2	1
ValRS/IleRS/LeuRS editing domain	tRNA-binding arm	2	2
Ribonuclease PH domain 2-like	Ribonuclease PH domain 2-like	2	2
Nitrite and sulphite reductase 4Fe-4S domain-like	Nitrite and sulphite reductase 4Fe-4S domain-like	2	1
RING/U-box	BRCT domain	2	2
Aldolase	Aminoacid dehydrogenase-like, N-terminal domain	2	1
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS)	Translation proteins	2	1
NAD(P)-binding Rossmann-fold domains	Succinyl-CoA synthetase domains	2	1
Macro domain-like	Zn-dependent exopeptidases	2	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	Type II DNA topoisomerase	2	2
Ubiquitin-like	Protein kinase-like (PK-like)	2	1
HCP-like	HIT/MYND zinc finger-like	2	2
F-box domain	LysM domain	2	1
Ribonuclease H-like	Nucleic acid-binding proteins	2	2
Nucleotidylyl transferase	Alpha-L RNA-binding motif	2	1
Concanavalin A-like lectins/glucanases	Calpain large subunit, middle domain (domain III)	2	1
2Fe-2S ferredoxin-like	Formate dehydrogenase/DMSO reductase, domains 1-3	2	1
Chromo domain-like	Acyl-CoA N-acyltransferases (Nat)	1	1
FKBP-like	Rhodanese/Cell cycle control phosphatase	1	1
DHS-like NAD/FAD-binding domain	Enolase C-terminal domain-like	1	1
Putative isomerase YbhE	RING/U-box	1	1
Ribokinase-like	Thiamin phosphate synthase	1	1
SAP domain	WGR domain-like	1	1
L-aspartase-like	Class II aaRS ABD-related	1	1
Alpha subunit of glutamate synthase, C-terminal domain	FAD/NAD(P)-binding domain	1	1
Carbamate kinase-like	Carbamate kinase-like	1	1
Class I glutamine amidotransferase-like	Adenine nucleotide alpha hydrolases-like	1	1
Adenine nucleotide alpha hydrolases-like	DHS-like NAD/FAD-binding domain	1	1
Staphylococcal nuclease	Tudor/PWWP/MBT	1	1
Enolase C-terminal domain-like	alpha/beta-Hydrolases	1	1
Nucleic acid-binding proteins	TPR-like	1	1
Urease, gamma-subunit	Composite domain of metallo-dependent hydrolases	1	1
Cryptochrome/photolyase, N-terminal domain	alpha/beta-Hydrolases	1	1
Metallo-hydrolase/oxidoreductase	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Staphylococcal nuclease	Staphylococcal nuclease	1	1
Protein kinase-like (PK-like)	Class II aaRS and biotin synthetases	1	1
Nucleoside hydrolase	Nucleoside hydrolase	1	1
UBA-like	P-loop containing nucleoside triphosphate hydrolases	1	1
WWE domain	ADP-ribosylation	1	1
PUA domain-like	SWIB/MDM2 domain	1	1
Metallo-dependent hydrolases	Glutamine synthetase, N-terminal domain	1	1
Dom34/Pelota N-terminal domain-like	L30e-like	1	1
HAD-like	NTF2-like	1	1
P-loop containing nucleoside triphosphate hydrolases	PLP-dependent transferases	1	1
dsRNA-binding domain-like	FKBP-like	1	1
ACT-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
MHC antigen-recognition domain	Protein kinase-like (PK-like)	1	1
Formate/glycerate dehydrogenase catalytic domain-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
MurCD N-terminal domain	MurD-like peptide ligases, peptide-binding domain	1	1
Translation proteins	Nucleotide-diphospho-sugar transferases	1	1
HMG-box	TRAF domain-like	1	1
Cap-Gly domain	L domain-like	1	1
Oxidoreductase molybdopterin-binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
HIT-like	HIT-like	1	1
Activator of Hsp90 ATPase, Aha1	Bet v1-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	S13-like H2TH domain	1	1
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	Protein kinase-like (PK-like)	1	1
CarD-like	P-loop containing nucleoside triphosphate hydrolases	1	1
FAD-binding/transporter-associated domain-like	Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain	1	1
DNA-binding domain	DNA-binding pseudobarrel domain	1	1
PRP4-like	Functional domain of the splicing factor Prp18	1	1
Endosomal sorting complex assembly domain	VPS28 C-terminal domain-like	1	1
Class II aaRS and biotin synthetases	Anticodon-binding domain of PheRS	1	1
Elongation factor Ts (EF-Ts), dimerisation domain	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
RNA-binding domain, RBD	ENTH/VHS domain	1	1
P-loop containing nucleoside triphosphate hydrolases	HIT-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	alpha-helical ferredoxin	1	1
cAMP-binding domain-like	Protein kinase-like (PK-like)	1	1
PIN domain-like	Nucleic acid-binding proteins	1	1
Metallo-dependent hydrolases	Glutamine synthetase/guanido kinase	1	1
Cysteine-rich domain	FYVE/PHD zinc finger	1	1
beta-Galactosidase/glucuronidase domain	Galactose mutarotase-like	1	1
Second domain of FERM	P-loop containing nucleoside triphosphate hydrolases	1	1
5' to 3' exonuclease, C-terminal subdomain	Chromo domain-like	1	1
HIT/MYND zinc finger-like	Creatinase/aminopeptidase	1	1
Prokaryotic type I DNA topoisomerase	Retrovirus zinc finger-like domains	1	1
Formin homology 2 domain (FH2 domain)	CAD & PB1 domains	1	1
Nucleic acid-binding proteins	GAD domain-like	1	1
Trigger factor ribosome-binding domain	FKBP-like	1	1
Phospholipase C/P1 nuclease	Phospholipase C/P1 nuclease	1	1
cAMP-binding domain-like	cAMP-binding domain-like	1	1
SAP domain	CCCH zinc finger	1	1
GST C-terminal domain-like	Nucleotidylyl transferase	1	1
Adenine nucleotide alpha hydrolases-like	GMP synthetase C-terminal dimerisation domain	1	1
PurM N-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Fumarylacetoacetate hydrolase, FAH, N-terminal domain	FAH	1	1
Flavoproteins	Radical SAM enzymes	1	1
FAD/NAD(P)-binding domain	HI0933 insert domain-like	1	1
Surp module (SWAP domain)	ENTH/VHS domain	1	1
Protein kinase-like (PK-like)	(Phosphotyrosine protein) phosphatases II	1	1
Nucleotide-diphospho-sugar transferases	Nucleotide-diphospho-sugar transferases	1	1
EGF/Laminin	Protein kinase-like (PK-like)	1	1
SufE/NifU	BolA-like	1	1
FMN-linked oxidoreductases	FAD/NAD(P)-binding domain	1	1
Alpha subunit of glutamate synthase, C-terminal domain	alpha-helical ferredoxin	1	1
E set domains	RNA-binding domain, RBD	1	1
DNA repair protein MutS, domain III	SMR domain-like	1	1
Six-hairpin glycosidases	Six-hairpin glycosidases	1	1
Class I glutamine amidotransferase-like	GMP synthetase C-terminal dimerisation domain	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase C-terminal domain-like	1	1
Single hybrid motif	ClpP/crotonase	1	1
L-aspartase-like	Class II aaRS and biotin synthetases	1	1
Oxidoreductase molybdopterin-binding domain	Cytochrome b5-like heme/steroid binding domain	1	1
Methionyl-tRNA synthetase (MetRS), Zn-domain	Nucleic acid-binding proteins	1	1
DNA polymerase beta, N-terminal domain-like	PsbU/PolX domain-like	1	1
Molybdenum cofactor biosynthesis proteins	Molybdenum cofactor biosynthesis proteins	1	1
HD-domain/PDEase-like	ACT-like	1	1
HAD-like	NHL repeat	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	1	1
Starch-binding domain-like	Glutathione synthetase ATP-binding domain-like	1	1
Macro domain-like	HIT-like	1	1
WD40 repeat-like	Cyclophilin-like	1	1
PH domain-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
PreATP-grasp domain	ClpP/crotonase	1	1
YjgF-like	YjgF-like	1	1
Lysozyme-like	Lysozyme-like	1	1
Protein kinase-like (PK-like)	NTF2-like	1	1
Ribonuclease H-like	Eukaryotic type KH-domain (KH-domain type I)	1	1
MHC antigen-recognition domain	ARM repeat	1	1
Pectin lyase-like	L domain-like	1	1
FKBP-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
SAM/Pointed domain	Metallo-hydrolase/oxidoreductase	1	1
Tex N-terminal region-like	SH2 domain	1	1
UBC-like	UBA-like	1	1
Protein kinase-like (PK-like)	beta-lactamase/transpeptidase-like	1	1
Enolase N-terminal domain-like	alpha/beta-Hydrolases	1	1
Thioredoxin-like	VC0467-like	1	1
PreATP-grasp domain	PreATP-grasp domain	1	1
Chaperone J-domain	CSL zinc finger	1	1
Probable bacterial effector-binding domain	Probable bacterial effector-binding domain	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK	Dihydropteroate synthetase-like	1	1
PUA domain-like	eIF1-like	1	1
WD40 repeat-like	C-terminal (heme d1) domain of cytochrome cd1-nitrite reductase	1	1
Carbamoyl phosphate synthetase, small subunit N-terminal domain	Class I glutamine amidotransferase-like	1	1
RING/U-box	Cyclophilin-like	1	1
Trigger factor ribosome-binding domain	Triger factor/SurA peptide-binding domain-like	1	1
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain	Nucleotidylyl transferase	1	1
Urease, beta-subunit	Composite domain of metallo-dependent hydrolases	1	1
Acyl-CoA N-acyltransferases (Nat)	BRCT domain	1	1
DAK1/DegV-like	DhaL-like	1	1
USP8 N-terminal domain-like	JAB1/MPN domain	1	1
Nucleotidyltransferase	EF-hand	1	1
FYVE/PHD zinc finger	CCCH zinc finger	1	1
Pectin lyase-like	Pectin lyase-like	1	1
N-utilization substance G protein NusG, N-terminal domain	Translation proteins SH3-like domain	1	1
PH domain-like	"Winged helix" DNA-binding domain	1	1
Thiamin diphosphate-binding fold (THDP-binding)	Enolase N-terminal domain-like	1	1
Hypothetical protein AF0491, middle domain	beta-beta-alpha zinc fingers	1	1
E set domains	CBS-domain pair	1	1
RuvA domain 2-like	SH2 domain	1	1
Glutathione synthetase ATP-binding domain-like	ClpP/crotonase	1	1
PH domain-like	(Phosphotyrosine protein) phosphatases II	1	1
P-loop containing nucleoside triphosphate hydrolases	Obg GTP-binding protein C-terminal domain	1	1
LysM domain	LysM domain	1	1
Calcium-dependent phosphotriesterase	Quinoprotein alcohol dehydrogenase-like	1	1
GroEL-intermediate domain like	GroEL-intermediate domain like	1	1
Nqo1 middle domain-like	Nqo1C-terminal domain-like	1	1
Homeodomain-like	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	1	1
SSo0622-like	Kelch motif	1	1
GAF domain-like	CAD & PB1 domains	1	1
IlvD/EDD N-terminal domain-like	LeuD/IlvD-like	1	1
Hermes dimerisation domain	Ribonuclease H-like	1	1
Ubiquitin-like	P-loop containing nucleoside triphosphate hydrolases	1	1
vWA-like	C-terminal domain of Ku80	1	1
TPR-like	Metallo-dependent phosphatases	1	1
Putative isomerase YbhE	ARM repeat	1	1
F-box domain	P-loop containing nucleoside triphosphate hydrolases	1	1
GYF domain	SET domain	1	1
PRC-barrel domain	Nucleotide-diphospho-sugar transferases	1	1
PreATP-grasp domain	Methylglyoxal synthase-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Elongation factor TFIIS domain 2	1	1
Phosphoglycerate kinase	S-adenosyl-L-methionine-dependent methyltransferases	1	1
SMI1/KNR4-like	ApaG-like	1	1
FYSH domain	beta-beta-alpha zinc fingers	1	1
SAP domain	SAP domain	1	1
TGS-like	Class II aaRS and biotin synthetases	1	1
UBA-like	Hect, E3 ligase catalytic domain	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	RING/U-box	1	1
Chaperone J-domain	Homeodomain-like	1	1
BRCT domain	DNA/RNA polymerases	1	1
P-loop containing nucleoside triphosphate hydrolases	Prismane protein-like	1	1
lambda repressor-like DNA-binding domains	Cyanase C-terminal domain	1	1
Taf5 N-terminal domain-like	WD40 repeat-like	1	1
SSo0622-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
PIN domain-like	Chromo domain-like	1	1
POZ domain	Galactose-binding domain-like	1	1
Ribosomal protein S5 domain 2-like	DNA mismatch repair protein MutL	1	1
Ferredoxin reductase-like, C-terminal NADP-linked domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Ankyrin repeat	Pseudo ankyrin repeat-like	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	Protein kinase-like (PK-like)	1	1
TGS-like	ACT-like	1	1
DNA ligase/mRNA capping enzyme, catalytic domain	BRCT domain	1	1
SNARE-like	Domain of the SRP/SRP receptor G-proteins	1	1
DNA polymerase beta, N-terminal domain-like	Nucleotidyltransferase	1	1
PsbU/PolX domain-like	Nucleotidyltransferase	1	1
Cna protein B-type domain	Cna protein B-type domain	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	FAD/NAD(P)-binding domain	1	1
RNA-binding domain, RBD	Clavaminate synthase-like	1	1
Nqo1 FMN-binding domain-like	Nqo1C-terminal domain-like	1	1
Chaperone J-domain	beta-beta-alpha zinc fingers	1	1
Kelch motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Six-hairpin glycosidases	Carbohydrate-binding domain	1	1
Protein prenylyltransferase	L domain-like	1	1
PDZ domain-like	Terpenoid synthases	1	1
NAD(P)-binding Rossmann-fold domains	YgbK-like	1	1
FMN-linked oxidoreductases	alpha-helical ferredoxin	1	1
ARM repeat	HMA, heavy metal-associated domain	1	1
Riboflavin synthase domain-like	Riboflavin synthase domain-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	WGR domain-like	1	1
AraD/HMP-PK domain-like	HAD-like	1	1
P-loop containing nucleoside triphosphate hydrolases	DNA/RNA polymerases	1	1
Nucleic acid-binding proteins	UBA-like	1	1
N-terminal nucleophile aminohydrolases (Ntn hydrolases)	SIS domain	1	1
Actin depolymerizing proteins	C-terminal, gelsolin-like domain of Sec23/24	1	1
Carbamate kinase-like	Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain	1	1
Double Clp-N motif	Double Clp-N motif	1	1
vWA-like	SAP domain	1	1
ARM repeat	alpha/beta-Hydrolases	1	1
Nucleic acid-binding proteins	BRCT domain	1	1
PurS-like	FGAM synthase PurL, linker domain	1	1
HAD-like	HAD-like	1	1
E set domains	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
Actin-like ATPase domain	AF1104-like	1	1
CBS-domain pair	Inosine monophosphate dehydrogenase (IMPDH)	1	1
Glucocorticoid receptor-like (DNA-binding domain)	HAD-like	1	1
SNARE-like	SNARE-like	1	1
Surp module (SWAP domain)	Surp module (SWAP domain)	1	1
Glucocorticoid receptor-like (DNA-binding domain)	ADP-ribosylation	1	1
GYF domain	CCCH zinc finger	1	1
F-box domain	Actin-like ATPase domain	1	1
R3H domain	P-loop containing nucleoside triphosphate hydrolases	1	1
Clavaminate synthase-like	Protein kinase-like (PK-like)	1	1
Thiamin pyrophosphokinase, catalytic domain	Thiamin pyrophosphokinase, substrate-binding domain	1	1
FAD/NAD(P)-binding domain	4Fe-4S ferredoxins	1	1
HCP-like	Homing endonucleases	1	1
E set domains	Riboflavin synthase domain-like	1	1
Oxygen-evolving enhancer protein 3,	Cyclophilin-like	1	1
Fucose-specific lectin	Fucose-specific lectin	1	1
Formyltransferase	FMT C-terminal domain-like	1	1
Aspartate/glutamate racemase	Aspartate/glutamate racemase	1	1
Phosphoglycerate kinase	Phosphoglycerate kinase	1	1
Glucocorticoid receptor-like (DNA-binding domain)	BRCT domain	1	1
GST C-terminal domain-like	Nucleic acid-binding proteins	1	1
Kelch motif	Galactose oxidase, central domain	1	1
Thioredoxin-like	Cysteine-rich domain	1	1
C-type lectin-like	Protein kinase-like (PK-like)	1	1
"Winged helix" DNA-binding domain	Protein kinase-like (PK-like)	1	1
PurS-like	PurM N-terminal domain-like	1	1
SWIB/MDM2 domain	eIF1-like	1	1
DUSP-like	Ubiquitin-like	1	1
Chitinase insertion domain	Protein kinase-like (PK-like)	1	1
BRCT domain	Lesion bypass DNA polymerase (Y-family), little finger domain	1	1
Adenine nucleotide alpha hydrolases-like	YjgF-like	1	1
Rhomboid-like	Ran binding protein zinc finger-like	1	1
PurM C-terminal domain-like	PurM C-terminal domain-like	1	1
HisI-like	all-alpha NTP pyrophosphatases	1	1
Ubiquitin-like	F-box domain	1	1
Cytidine deaminase-like	Cytidine deaminase-like	1	1
Oxidoreductase molybdopterin-binding domain	Riboflavin synthase domain-like	1	1
Metallo-hydrolase/oxidoreductase	Nucleic acid-binding proteins	1	1
EF-hand	TPR-like	1	1
Galactose-binding domain-like	Glycosyl hydrolase domain	1	1
(Phosphotyrosine protein) phosphatases II	(Phosphotyrosine protein) phosphatases II	1	1
FMN-dependent nitroreductase-like	FMN-dependent nitroreductase-like	1	1
Clavaminate synthase-like	beta-beta-alpha zinc fingers	1	1
PLP-dependent transferases	Ornithine decarboxylase C-terminal domain	1	1
Chelatase	Chelatase	1	1
Chelatase	Chlorophyll a-b binding protein	1	1
beta-beta-alpha zinc fingers	CCCH zinc finger	1	1
Starch-binding domain-like	Starch-binding domain-like	1	1
BRCT domain	DNA polymerase beta, N-terminal domain-like	1	1
Chaperone J-domain	Thioredoxin-like	1	1
Protein kinase-like (PK-like)	BEACH domain	1	1
Cna protein B-type domain	Starch-binding domain-like	1	1
UBC-like	Class II aaRS and biotin synthetases	1	1
Metalloproteases ("zincins"), catalytic domain	HAD-like	1	1
ATP-dependent DNA ligase DNA-binding domain	BRCT domain	1	1
"Winged helix" DNA-binding domain	HRDC-like	1	1
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases	Nucleic acid-binding proteins	1	1
F-box domain	SMI1/KNR4-like	1	1
Cytochrome b5-like heme/steroid binding domain	Ferredoxin reductase-like, C-terminal NADP-linked domain	1	1
DHS-like NAD/FAD-binding domain	alpha/beta-Hydrolases	1	1
Protein kinase-like (PK-like)	Class II aaRS ABD-related	1	1
(Phosphotyrosine protein) phosphatases II	NAD kinase/diacylglycerol kinase-like	1	1
UDP-Glycosyltransferase/glycogen phosphorylase	Protein kinase-like (PK-like)	1	1
Nucleoplasmin-like core domain	FKBP-like	1	1
Acyl-CoA binding protein	Kelch motif	1	1
DUSP-like	DUSP-like	1	1
NAC domain	NAC domain	1	1
TGS-like	Class II aaRS ABD-related	1	1
F-box domain	SET domain	1	1
DPP6 N-terminal domain-like	Quinoprotein alcohol dehydrogenase-like	1	1
ssDNA-binding transcriptional regulator domain	Retrovirus zinc finger-like domains	1	1
SAP domain	RNA-binding domain, RBD	1	1
FGAM synthase PurL, linker domain	PurM C-terminal domain-like	1	1
Dom34/Pelota N-terminal domain-like	Translational machinery components	1	1
BRCA2 helical domain	BRCA2 tower domain	1	1
Pseudouridine synthase	PUA domain-like	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	Aldolase	1	1
Second domain of FERM	PH domain-like	1	1
Class I glutamine amidotransferase-like	Ribulose-phoshate binding barrel	1	1
Nqo1 FMN-binding domain-like	Nqo1 middle domain-like	1	1
PLP-dependent transferases	PK beta-barrel domain-like	1	1
Molybdenum cofactor biosynthesis proteins	MoeA C-terminal domain-like	1	1
Heme-dependent peroxidases	Heme-dependent peroxidases	1	1
ARM repeat	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Dihydrofolate reductase-like	YbiA-like	1	1
FGAM synthase PurL, linker domain	Class I glutamine amidotransferase-like	1	1
Rudiment single hybrid motif	ClpP/crotonase	1	1
TRAF domain-like	ACT-like	1	1
BRCA2 helical domain	Nucleic acid-binding proteins	1	1
F-box domain	Tricorn protease domain 2	1	1
Aldolase	Aldolase	1	1
NusB-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
ARID-like	Clavaminate synthase-like	1	1
Galactose-binding domain-like	ARM repeat	1	1
Histone-fold	ARM repeat	1	1
Starch-binding domain-like	Phosphoglycerate mutase-like	1	1
BSD domain-like	Formin homology 2 domain (FH2 domain)	1	1
Nucleic acid-binding proteins	BRCA2 tower domain	1	1
ARM repeat	SET domain	1	1
MurCD N-terminal domain	MurD-like peptide ligases, catalytic domain	1	1
Starch-binding domain-like	(Trans)glycosidases	1	1
Voltage-gated potassium channels	NAD(P)-binding Rossmann-fold domains	1	1
PH domain-like	Prismane protein-like	1	1
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70	Zinc beta-ribbon	1	1
SPOC domain-like	C-terminal domain of Ku80	1	1
FGAM synthase PurL, linker domain	PurM N-terminal domain-like	1	1
dsRNA-binding domain-like	S-adenosyl-L-methionine-dependent methyltransferases	1	1
DNA-binding domain	Bromodomain	1	1
MoeA N-terminal region -like	Molybdenum cofactor biosynthesis proteins	1	1
DHS-like NAD/FAD-binding domain	Enolase N-terminal domain-like	1	1
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain	Alkaline phosphatase-like	1	1
PUA domain-like	alpha/beta knot	1	1
P-loop containing nucleoside triphosphate hydrolases	Phosphoglycerate mutase-like	1	1
Pseudouridine synthase	Pseudouridine synthase	1	1
RNI-like	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
HAD-like	Thioredoxin-like	1	1
PDZ domain-like	Rubredoxin-like	1	1
BRCT domain	Nucleotidyltransferase	1	1
Nucleic acid-binding proteins	Retrovirus zinc finger-like domains	1	1
Surp module (SWAP domain)	Ubiquitin-like	1	1
Nucleotide-diphospho-sugar transferases	ARM repeat	1	1
TPR-like	Protein prenylyltransferase	1	1
DNA-glycosylase	Nudix	1	1
DNA primase core	P-loop containing nucleoside triphosphate hydrolases	1	1
SPOC domain-like	SAP domain	1	1
F-box domain	Calcium-dependent phosphotriesterase	1	1
Metalloproteases ("zincins"), catalytic domain	Frizzled cysteine-rich domain	1	1
Cyclophilin-like	RNA-binding domain, RBD	1	1
Nucleic acid-binding proteins	Elongation factor Ts (EF-Ts), dimerisation domain	1	1
alpha-helical ferredoxin	FAD/NAD(P)-binding domain	1	1
R3H domain	Ankyrin repeat	1	1
PP2C-like	cAMP-binding domain-like	1	1
CBS-domain pair	FAD-binding/transporter-associated domain-like	1	1
FYSH domain	Hypothetical protein AF0491, middle domain	1	1
MoeA N-terminal region -like	MoeA C-terminal domain-like	1	1
UBC-like	Protein kinase-like (PK-like)	1	1
Thiamin phosphate synthase	P-loop containing nucleoside triphosphate hydrolases	1	1
S13-like H2TH domain	Ribosomal protein S5 domain 2-like	1	1
Sec63 N-terminal domain-like	DNA/RNA polymerases	1	1
(Phosphotyrosine protein) phosphatases II	Nucleic acid-binding proteins	1	1
ARM repeat	FabD/lysophospholipase-like	1	1
Translational machinery components	Translational machinery components	1	1
ACT-like	Formyltransferase	1	1
WD40 repeat-like	TPR-like	1	1
Rhodanese/Cell cycle control phosphatase	alpha/beta-Hydrolases	1	1
Aldolase	2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain	1	1
Chromo domain-like	Homeodomain-like	1	1
Carboxypeptidase regulatory domain-like	Starch-binding domain-like	1	1
F-box domain	Formin homology 2 domain (FH2 domain)	1	1
Cysteine proteinases	Sec-C motif	1	1
TAF(II)230 TBP-binding fragment	Ubiquitin-like	1	1
SAP domain	Domain of poly(ADP-ribose) polymerase	1	1
DEK C-terminal domain	ssDNA-binding transcriptional regulator domain	1	1
WW domain	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Tricorn protease N-terminal domain	DPP6 N-terminal domain-like	1	1
Cysteine proteinases	S-adenosyl-L-methionine-dependent methyltransferases	1	1
vWA-like	Cysteine-rich domain	1	1
Ubiquitin-like	Hect, E3 ligase catalytic domain	1	1
Protein prenylyltransferase	Thioredoxin-like	1	1
POZ domain	RNI-like	1	1
Glucocorticoid receptor-like (DNA-binding domain)	Domain of poly(ADP-ribose) polymerase	1	1
Metallo-hydrolase/oxidoreductase	ATP-dependent DNA ligase DNA-binding domain	1	1
RuBisCO, large subunit, small (N-terminal) domain	RuBisCo, C-terminal domain	1	1
Acid proteases	DNA/RNA polymerases	1	1
Formiminotransferase domain of formiminotransferase-cyclodeaminase.	Formiminotransferase domain of formiminotransferase-cyclodeaminase.	1	1
SMAD/FHA domain	PP2C-like	1	1
Cna protein B-type domain	Carboxypeptidase regulatory domain-like	1	1
(Phosphotyrosine protein) phosphatases II	DNA ligase/mRNA capping enzyme, catalytic domain	1	1
Ubiquitin-like	Ribosomal protein S19	1	1
Tricorn protease N-terminal domain	Tricorn protease N-terminal domain	1	1
Cytochrome b5-like heme/steroid binding domain	Riboflavin synthase domain-like	1	1
CCCH zinc finger	WD40 repeat-like	1	1
PurS-like	PurM C-terminal domain-like	1	1
E set domains	Cytochrome b5-like heme/steroid binding domain	1	1
HMG-box	HMG-box	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase C-terminal domain-like	1	1
RNI-like	Glutathione synthetase ATP-binding domain-like	1	1
Bromodomain	FYVE/PHD zinc finger	1	1
SNARE-like	P-loop containing nucleoside triphosphate hydrolases	1	1
F-box domain	ApaG-like	1	1
Saposin	Saposin	1	1
Cysteine proteinases	UBA-like	1	1
Cytidine deaminase-like	Dihydrofolate reductase-like	1	1
P-loop containing nucleoside triphosphate hydrolases	TRCF domain-like	1	1
Translation proteins	PRC-barrel domain	1	1
Glutathione synthetase ATP-binding domain-like	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
PurM N-terminal domain-like	PurM N-terminal domain-like	1	1
Nucleic acid-binding proteins	SH2 domain	1	1
Zn-dependent exopeptidases	Carboxypeptidase regulatory domain-like	1	1
Bactericidal permeability-increasing protein, BPI	Bactericidal permeability-increasing protein, BPI	1	1
Calponin-homology domain, CH-domain	ARM repeat	1	1
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment	DNA breaking-rejoining enzymes	1	1
Chromo domain-like	Ankyrin repeat	1	1
RNA-binding domain, RBD	Surp module (SWAP domain)	1	1
Cytochrome c oxidase subunit II-like, transmembrane region	Cupredoxins	1	1
Type II DNA topoisomerase	GyrA/ParC C-terminal domain-like	1	1
UBC-like	Class II aaRS ABD-related	1	1
FAD/NAD(P)-binding domain	alpha/beta-Hydrolases	1	1
Ankyrin repeat	S-adenosyl-L-methionine-dependent methyltransferases	1	1
(Trans)glycosidases	Protein kinase-like (PK-like)	1	1
TGS-like	ThrRS/AlaRS common domain	1	1
Elongation factor TFIIS domain 2	Zinc beta-ribbon	1	1
Thioredoxin-like	Six-hairpin glycosidases	1	1
ARM repeat	Chaperone J-domain	1	1
SAP domain	ADP-ribosylation	1	1
GYF domain	RNA-binding domain, RBD	1	1
TPR-like	PUA domain-like	1	1
RNA-binding domain, RBD	DPP6 N-terminal domain-like	1	1
FYVE/PHD zinc finger	ARM repeat	1	1
Cysteine-rich domain	NAD kinase/diacylglycerol kinase-like	1	1
Tudor/PWWP/MBT	Tudor/PWWP/MBT	1	1
6-phosphogluconate dehydrogenase C-terminal domain-like	YgbK-like	1	1
PurS-like	Class I glutamine amidotransferase-like	1	1
CCCH zinc finger	S-adenosyl-L-methionine-dependent methyltransferases	1	1
BRCT domain	PsbU/PolX domain-like	1	1
PK C-terminal domain-like	PK C-terminal domain-like	1	1
RING/U-box	Formin homology 2 domain (FH2 domain)	1	1
Multidrug efflux transporter AcrB transmembrane domain	Multidrug efflux transporter AcrB transmembrane domain	1	1
Carbamoyl phosphate synthetase, large subunit connection domain	Methylglyoxal synthase-like	1	1
Class I glutamine amidotransferase-like	ADC synthase	1	1
Alpha-L RNA-binding motif	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Ubiquitin-like	Acid proteases	1	1
Urease, beta-subunit	Metallo-dependent hydrolases	1	1
Zinc beta-ribbon	Zinc beta-ribbon	1	1
RNA-binding domain, RBD	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Rudiment single hybrid motif	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
ARM repeat	UBA-like	1	1
Eukaryotic type KH-domain (KH-domain type I)	LigT-like	1	1
alpha/beta-Hydrolases	P-loop containing nucleoside triphosphate hydrolases	1	1
Chaperone J-domain	Chaperone J-domain	1	1
DNA-binding domain	FYVE/PHD zinc finger	1	1
F-box domain	Protein kinase-like (PK-like)	1	1
PDZ domain-like	TPR-like	1	1
FAD/NAD(P)-binding domain	NAD(P)-binding Rossmann-fold domains	1	1
Glutathione synthetase ATP-binding domain-like	Methylglyoxal synthase-like	1	1
Metallo-hydrolase/oxidoreductase	Metallo-hydrolase/oxidoreductase	1	1
POZ domain	Pentapeptide repeat-like	1	1
FKBP-like	Triger factor/SurA peptide-binding domain-like	1	1
POZ domain	WD40 repeat-like	1	1
ARM repeat	Tudor/PWWP/MBT	1	1
Concanavalin A-like lectins/glucanases	RING/U-box	1	1
Class II aaRS and biotin synthetases	GAD domain-like	1	1
Thioredoxin-like	NHL repeat	1	1
Obg GTP-binding protein N-terminal domain	Obg GTP-binding protein C-terminal domain	1	1
FAD-linked reductases, C-terminal domain	4Fe-4S ferredoxins	1	1
TPR-like	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)	1	1
Thiamin diphosphate-binding fold (THDP-binding)	alpha/beta-Hydrolases	1	1
F-box domain	Putative isomerase YbhE	1	1
Cation efflux protein cytoplasmic domain-like	Cation efflux protein cytoplasmic domain-like	1	1
Urease, gamma-subunit	Metallo-dependent hydrolases	1	1
P-loop containing nucleoside triphosphate hydrolases	SMR domain-like	1	1
RNI-like	WD40 repeat-like	1	1
Cysteine proteinases	Cysteine proteinases	1	1
alpha-ketoacid dehydrogenase kinase, N-terminal domain	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Putative methyltransferase TM0872, insert domain	1	1
S-adenosyl-L-methionine-dependent methyltransferases	Formin homology 2 domain (FH2 domain)	1	1
L domain-like	FabD/lysophospholipase-like	1	1
FYVE/PHD zinc finger	Ankyrin repeat	1	1
Glutathione synthetase ATP-binding domain-like	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
Glutamine synthetase/guanido kinase	GatB/YqeY motif	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	alpha/beta-Hydrolases	1	1
WD40 repeat-like	Tricorn protease domain 2	1	1
Pre-PUA domain	PUA domain-like	1	1
Formin homology 2 domain (FH2 domain)	Formin homology 2 domain (FH2 domain)	1	1
Urease, gamma-subunit	Urease, beta-subunit	1	1
C-terminal, gelsolin-like domain of Sec23/24	VHP, Villin headpiece domain	1	1
C2 domain (Calcium/lipid-binding domain, CaLB)	MHC antigen-recognition domain	1	1
HLH, helix-loop-helix DNA-binding domain	ACT-like	1	1
beta-beta-alpha zinc fingers	S-adenosyl-L-methionine-dependent methyltransferases	1	1
Actin-like ATPase domain	HD-domain/PDEase-like	1	1
Second domain of FERM	Prismane protein-like	1	1
Nucleotidyltransferase	ACT-like	1	1
PreATP-grasp domain	Carbamoyl phosphate synthetase, large subunit connection domain	1	1
cAMP-binding domain-like	Thioesterase/thiol ester dehydrase-isomerase	1	1
FAD/NAD(P)-binding domain	SMAD/FHA domain	1	1
ClpP/crotonase	Terpenoid synthases	1	1
Acid proteases	UBA-like	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	1	1
PurM C-terminal domain-like	Class I glutamine amidotransferase-like	1	1
Protein kinase-like (PK-like)	Acyl-CoA dehydrogenase NM domain-like	1	1
CarD-like	TRCF domain-like	1	1
YgbK-like	Aldolase	1	1
SAP domain	FYVE/PHD zinc finger	1	1
Calcyclin-binding protein-like	HSP20-like chaperones	1	1
FabD/lysophospholipase-like	Probable ACP-binding domain of malonyl-CoA ACP transacylase	1	1
PreATP-grasp domain	N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE)	1	1
HD-domain/PDEase-like	EF-hand	1	1
SMAD/FHA domain	BRCT domain	1	1
Thioredoxin-like	ERP29 C domain-like	1	1
Nucleotidylyl transferase	Nucleic acid-binding proteins	1	1
Carbamate kinase-like	NAD(P)-binding Rossmann-fold domains	1	1
Cystatin/monellin	Cystatin/monellin	1	1
Ankyrin repeat	RCC1/BLIP-II	1	1
Tricorn protease domain 2	alpha/beta-Hydrolases	1	1
L domain-like	ARM repeat	1	1
N-terminal domain of MutM-like DNA repair proteins	S13-like H2TH domain	1	1
Dihydrofolate reductase-like	Thymidylate synthase/dCMP hydroxymethylase	1	1
GST C-terminal domain-like	Ribosomal protein L25-like	1	1
Chaperone J-domain	HSC20 (HSCB), C-terminal oligomerisation domain	1	1
P-loop containing nucleoside triphosphate hydrolases	Glucocorticoid receptor-like (DNA-binding domain)	1	1
Cytidine deaminase-like	YbiA-like	1	1
PLP-dependent transferases	MOSC N-terminal domain-like	1	1
SET domain	SET domain	1	1
P-loop containing nucleoside triphosphate hydrolases	C2 domain (Calcium/lipid-binding domain, CaLB)	1	1
Radical SAM enzymes	Acyl-CoA N-acyltransferases (Nat)	1	1
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase	DNA mismatch repair protein MutL	1	1
TPR-like	RNI-like	1	1
Ribonuclease H-like	SH2 domain	1	1
UBA-like	NSFL1 (p97 ATPase) cofactor p47, SEP domain	1	1
Periplasmic binding protein-like II	Periplasmic binding protein-like II	1	1
PYP-like sensor domain (PAS domain)	Homodimeric domain of signal transducing histidine kinase	1	1