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Domain combination pairs in Deinococcus geothermalis DSM 11300

All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.

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Adjacent domain pairs graph

Graph of adjacent domain pairs.


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Domain combination pairs

592 domain combination pairs.
Click on a column heading to sort that column, or the 'View' button to see domain architetures for that domain pair combination.

Superfamily (N) Superfamily (C) Number of occurrances Number unique
P-loop containing nucleoside triphosphate hydrolases P-loop containing nucleoside triphosphate hydrolases 2112
Homodimeric domain of signal transducing histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 2110
CheY-like C-terminal effector domain of the bipartite response regulators 151
Actin-like ATPase domain Actin-like ATPase domain 133
NAD(P)-binding Rossmann-fold domains 6-phosphogluconate dehydrogenase C-terminal domain-like 125
Acyl-CoA dehydrogenase NM domain-like Acyl-CoA dehydrogenase C-terminal domain-like 114
NAD(P)-binding Rossmann-fold domains Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 113
Aminoacid dehydrogenase-like, N-terminal domain NAD(P)-binding Rossmann-fold domains 94
lambda repressor-like DNA-binding domains Periplasmic binding protein-like I 81
GroES-like NAD(P)-binding Rossmann-fold domains 81
P-loop containing nucleoside triphosphate hydrolases Translation proteins 85
PYP-like sensor domain (PAS domain) ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 87
Composite domain of metallo-dependent hydrolases Metallo-dependent hydrolases 84
HAMP domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 71
HAMP domain-like Homodimeric domain of signal transducing histidine kinase 71
HAD-like Calcium ATPase, transmembrane domain M 74
(Trans)glycosidases Glycosyl hydrolase domain 74
Calcium ATPase, transduction domain A HAD-like 74
Multidrug resistance efflux transporter EmrE Multidrug resistance efflux transporter EmrE 72
"Winged helix" DNA-binding domain GAF domain-like 71
Calcium ATPase, transduction domain A Calcium ATPase, transmembrane domain M 74
PYP-like sensor domain (PAS domain) Homodimeric domain of signal transducing histidine kinase 76
Nucleic acid-binding proteins Nucleic acid-binding proteins 76
Thiamin diphosphate-binding fold (THDP-binding) Thiamin diphosphate-binding fold (THDP-binding) 64
P-loop containing nucleoside triphosphate hydrolases Ribosomal protein S5 domain 2-like 65
HMA, heavy metal-associated domain Calcium ATPase, transmembrane domain M 63
HMA, heavy metal-associated domain Calcium ATPase, transduction domain A 63
PYP-like sensor domain (PAS domain) GAF domain-like 65
Nucleotidylyl transferase Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 66
GAF domain-like GAF domain-like 64
TPR-like TPR-like 65
Acyl-CoA N-acyltransferases (Nat) Acyl-CoA N-acyltransferases (Nat) 62
cAMP-binding domain-like "Winged helix" DNA-binding domain 61
Trypsin-like serine proteases PDZ domain-like 62
MurD-like peptide ligases, catalytic domain MurD-like peptide ligases, peptide-binding domain 64
GAF domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 65
HMA, heavy metal-associated domain HAD-like 63
PreATP-grasp domain Glutathione synthetase ATP-binding domain-like 63
Thiolase-like Thiolase-like 61
Homeodomain-like Tetracyclin repressor-like, C-terminal domain 51
Thiamin diphosphate-binding fold (THDP-binding) TK C-terminal domain-like 53
Sigma2 domain of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 53
ParB/Sulfiredoxin KorB DNA-binding domain-like 51
P-loop containing nucleoside triphosphate hydrolases EF-G C-terminal domain-like 53
Translation proteins EF-G C-terminal domain-like 53
ABC transporter transmembrane region P-loop containing nucleoside triphosphate hydrolases 51
Zn-dependent exopeptidases Bacterial exopeptidase dimerisation domain 51
Nucleic acid-binding proteins Class II aaRS and biotin synthetases 53
PLP-binding barrel Alanine racemase C-terminal domain-like 43
LuxS/MPP-like metallohydrolase LuxS/MPP-like metallohydrolase 43
HMA, heavy metal-associated domain HMA, heavy metal-associated domain 42
Multidrug efflux transporter AcrB transmembrane domain Multidrug efflux transporter AcrB transmembrane domain 43
EF-G C-terminal domain-like EF-G C-terminal domain-like 42
GAF domain-like Homodimeric domain of signal transducing histidine kinase 43
Class II aaRS and biotin synthetases Class II aaRS ABD-related 44
"Winged helix" DNA-binding domain Periplasmic binding protein-like II 41
Enolase N-terminal domain-like Enolase C-terminal domain-like 41
GAF domain-like Nucleotide cyclase 32
GreA transcript cleavage protein, N-terminal domain FKBP-like 31
ValRS/IleRS/LeuRS editing domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 33
CheY-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 33
ClpP/crotonase ClpP/crotonase 31
FKBP-like Triger factor/SurA peptide-binding domain-like 33
Phosphoglucomutase, first 3 domains Phosphoglucomutase, first 3 domains 32
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex CoA-dependent acyltransferases 33
P-loop containing nucleoside triphosphate hydrolases FtsH protease domain-like 31
E set domains (Trans)glycosidases 32
CorA soluble domain-like Magnesium transport protein CorA, transmembrane region 31
Phosphohistidine domain Phosphoenolpyruvate/pyruvate domain 33
Single hybrid motif Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex 33
Single hybrid motif CoA-dependent acyltransferases 33
Ribosomal protein S5 domain 2-like GHMP Kinase, C-terminal domain 31
MalF N-terminal region-like MetI-like 31
E set domains Glycosyl hydrolase domain 32
EF-G C-terminal domain-like Ribosomal protein S5 domain 2-like 32
P-loop containing nucleoside triphosphate hydrolases TPR-like 33
"Winged helix" DNA-binding domain Chorismate lyase-like 31
Formate dehydrogenase/DMSO reductase, domains 1-3 ADC-like 32
Formate/glycerate dehydrogenase catalytic domain-like NAD(P)-binding Rossmann-fold domains 32
Lysozyme-like beta-lactamase/transpeptidase-like 32
Galactose-binding domain-like Galactose-binding domain-like 33
ValRS/IleRS/LeuRS editing domain Nucleotidylyl transferase 33
PYP-like sensor domain (PAS domain) PYP-like sensor domain (PAS domain) 33
P-loop containing nucleoside triphosphate hydrolases Hypothetical protein YjiA, C-terminal domain 31
Double Clp-N motif P-loop containing nucleoside triphosphate hydrolases 32
Rhodanese/Cell cycle control phosphatase Rhodanese/Cell cycle control phosphatase 32
Metallo-dependent phosphatases 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain 33
PreATP-grasp domain Rudiment single hybrid motif 31
FAD/NAD(P)-binding domain FAD/NAD-linked reductases, dimerisation (C-terminal) domain 31
Phosphoglucomutase, first 3 domains Phosphoglucomutase, C-terminal domain 32
LysM domain LysM domain 33
PDZ domain-like ClpP/crotonase 32
MetI-like MetI-like 32
Glutathione synthetase ATP-binding domain-like Rudiment single hybrid motif 31
GAF domain-like HD-domain/PDEase-like 32
LysM domain Duplicated hybrid motif 33
CheY-like Homodimeric domain of signal transducing histidine kinase 33
P-loop containing nucleoside triphosphate hydrolases Class I glutamine amidotransferase-like 31
MurCD N-terminal domain MurD-like peptide ligases, peptide-binding domain 22
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Ribosomal protein S5 domain 2-like 22
Nitrite/Sulfite reductase N-terminal domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 22
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain 21
MurCD N-terminal domain MurD-like peptide ligases, catalytic domain 22
DNA repair protein MutS, domain III P-loop containing nucleoside triphosphate hydrolases 22
Phospholipase D/nuclease Phospholipase D/nuclease 22
Homeodomain-like Homeodomain-like 22
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 21
FAD/NAD(P)-binding domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
PUA domain-like S-adenosyl-L-methionine-dependent methyltransferases 21
4Fe-4S ferredoxins Formate dehydrogenase/DMSO reductase, domains 1-3 22
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain 21
ClpP/crotonase NAD(P)-binding Rossmann-fold domains 22
Nucleic acid-binding proteins RuvA domain 2-like 22
FAD/NAD(P)-binding domain FAD-linked reductases, C-terminal domain 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphoenolpyruvate/pyruvate domain 22
Galactose-binding domain-like beta-Galactosidase/glucuronidase domain 21
"Winged helix" DNA-binding domain NagB/RpiA/CoA transferase-like 21
Nucleic acid-binding proteins P-loop containing nucleoside triphosphate hydrolases 22
P-loop containing nucleoside triphosphate hydrolases EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
MurE/MurF N-terminal domain MurD-like peptide ligases, peptide-binding domain 21
Serine metabolism enzymes domain ACT-like 22
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain Phosphohistidine domain 22
DNA methylase specificity domain DNA methylase specificity domain 21
Thiamin diphosphate-binding fold (THDP-binding) DHS-like NAD/FAD-binding domain 21
"Winged helix" DNA-binding domain Actin-like ATPase domain 22
Chaperone J-domain HSP40/DnaJ peptide-binding domain 22
ThrRS/AlaRS common domain Class II aaRS and biotin synthetases 22
FAD-binding/transporter-associated domain-like FAD-linked oxidases, C-terminal domain 22
Aminopeptidase/glucanase lid domain Zn-dependent exopeptidases 21
P-loop containing nucleoside triphosphate hydrolases C-terminal domain of alpha and beta subunits of F1 ATP synthase 22
beta-Galactosidase/glucuronidase domain (Trans)glycosidases 21
P-loop containing nucleoside triphosphate hydrolases "Winged helix" DNA-binding domain 22
ACT-like ACT-like 22
"Winged helix" DNA-binding domain Dimeric alpha+beta barrel 21
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB transmembrane domain 21
Translation proteins EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain 21
CO dehydrogenase molybdoprotein N-domain-like Molybdenum cofactor-binding domain 21
2Fe-2S ferredoxin-like CO dehydrogenase ISP C-domain like 22
HSP40/DnaJ peptide-binding domain HSP40/DnaJ peptide-binding domain 22
Ribosomal protein S5 domain 2-like Ribosomal protein S5 domain 2-like 22
FAD-binding/transporter-associated domain-like CO dehydrogenase flavoprotein C-terminal domain-like 22
LysM domain Cysteine proteinases 22
Nucleotide-binding domain Nucleotide-binding domain 22
PYP-like sensor domain (PAS domain) HD-domain/PDEase-like 22
FAD/NAD(P)-binding domain FAD/NAD(P)-binding domain 22
tRNA-binding arm Class II aaRS and biotin synthetases 21
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 22
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain 22
Putative DNA-binding domain Probable bacterial effector-binding domain 21
CBS-domain pair FAD-binding/transporter-associated domain-like 21
2Fe-2S ferredoxin-like 4Fe-4S ferredoxins 22
Translation proteins ThrRS/AlaRS common domain 22
L30e-like alpha/beta knot 21
Cation efflux protein transmembrane domain-like Cation efflux protein cytoplasmic domain-like 21
Galactose-binding domain-like (Trans)glycosidases 21
MurE/MurF N-terminal domain MurD-like peptide ligases, catalytic domain 21
2Fe-2S ferredoxin-like Formate dehydrogenase/DMSO reductase, domains 1-3 22
Glucocorticoid receptor-like (DNA-binding domain) P-loop containing nucleoside triphosphate hydrolases 22
Translation proteins SH3-like domain Nucleic acid-binding proteins 22
PUA domain-like P-loop containing nucleoside triphosphate hydrolases 22
HD-domain/PDEase-like P-loop containing nucleoside triphosphate hydrolases 22
PurM N-terminal domain-like PurM C-terminal domain-like 22
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains 21
DNA clamp DNA clamp 22
6-phosphogluconate dehydrogenase C-terminal domain-like 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Nucleotide-binding domain FAD-linked reductases, C-terminal domain 22
P-loop containing nucleoside triphosphate hydrolases post-AAA+ oligomerization domain-like 21
Nucleotide-diphospho-sugar transferases Trimeric LpxA-like enzymes 21
Translation proteins Ribosomal protein S5 domain 2-like 21
Nucleotidyltransferase Poly A polymerase C-terminal region-like 21
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains 21
EspE N-terminal domain-like EspE N-terminal domain-like 22
NAD(P)-binding Rossmann-fold domains ACT-like 22
Homeodomain-like SIS domain 21
Ribosomal protein S5 domain 2-like Ribonuclease PH domain 2-like 22
Nicotinate/Quinolinate PRTase N-terminal domain-like Nicotinate/Quinolinate PRTase C-terminal domain-like 21
PUA domain-like Ribosomal protein S5 domain 2-like 22
Alpha-L RNA-binding motif Pseudouridine synthase 21
ClpP/crotonase 6-phosphogluconate dehydrogenase C-terminal domain-like 22
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains Multidrug efflux transporter AcrB transmembrane domain 21
Sensory domain-like ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 22
HlyD-like secretion proteins HlyD-like secretion proteins 21
Sigma3 and sigma4 domains of RNA polymerase sigma factors Sigma3 and sigma4 domains of RNA polymerase sigma factors 22
Class II aaRS and biotin synthetases Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) 11
Ribosomal protein L25-like GatB/YqeY motif 11
PFL-like glycyl radical enzymes PFL-like glycyl radical enzymes 11
RuvA domain 2-like BRCT domain 11
Nucleic acid-binding proteins DNA helicase RuvA subunit, C-terminal domain 11
Glutathione synthetase ATP-binding domain-like Carbamoyl phosphate synthetase, large subunit connection domain 11
Galactose-binding domain-like Invasin/intimin cell-adhesion fragments 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Periplasmic binding protein-like II ACT-like 11
NAD(P)-binding Rossmann-fold domains LDH C-terminal domain-like 11
Riboflavin synthase domain-like Riboflavin synthase domain-like 11
Fucose-specific lectin Sialidases 11
Dihydropteroate synthetase-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
HD-domain/PDEase-like ACT-like 11
Fibronectin type III Carboxypeptidase regulatory domain-like 11
Oxidoreductase molybdopterin-binding domain E set domains 11
GIY-YIG endonuclease C-terminal UvrC-binding domain of UvrB 11
"Winged helix" DNA-binding domain GntR ligand-binding domain-like 11
FAD/NAD(P)-binding domain Nitrite/Sulfite reductase N-terminal domain-like 11
Class I glutamine amidotransferase-like Globin-like 11
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
(Trans)glycosidases Fibronectin type III 11
Dihydropteroate synthetase-like Methionine synthase activation domain-like 11
Nucleotidylyl transferase tRNA-binding arm 11
Glycosyl hydrolase domain Fibronectin type III 11
YjeF N-terminal domain-like Ribokinase-like 11
NagB/RpiA/CoA transferase-like D-ribose-5-phosphate isomerase (RpiA), lid domain 11
Translation initiation factor IF3, N-terminal domain Translation initiation factor IF3, C-terminal domain 11
DNA-glycosylase Nudix 11
Nitrite and sulphite reductase 4Fe-4S domain-like Nitrite and sulphite reductase 4Fe-4S domain-like 11
Tryptophan synthase beta subunit-like PLP-dependent enzymes ACT-like 11
Sensory domain-like Sporulation response regulatory protein Spo0B 11
Glycosyl hydrolase domain Carboxypeptidase regulatory domain-like 11
P-loop containing nucleoside triphosphate hydrolases Helical scaffold and wing domains of SecA 11
Galactose-binding domain-like Pectin lyase-like 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain II 11
R1 subunit of ribonucleotide reductase, N-terminal domain PFL-like glycyl radical enzymes 11
Prokaryotic type KH domain (KH-domain type II) Ribosomal protein S3 C-terminal domain 11
Homocysteine S-methyltransferase Cobalamin (vitamin B12)-binding domain 11
Rho N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
HAMP domain-like GAF domain-like 11
P-loop containing nucleoside triphosphate hydrolases SMR domain-like 11
TrkA C-terminal domain-like TrkA C-terminal domain-like 11
Nucleotide-diphospho-sugar transferases EspE N-terminal domain-like 11
"Winged helix" DNA-binding domain C-terminal domain of transcriptional repressors 11
Adenine nucleotide alpha hydrolases-like PheT/TilS domain 11
Adenine nucleotide alpha hydrolases-like GMP synthetase C-terminal dimerisation domain 11
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase alpha/beta-Hydrolases 11
TGS-like ACT-like 11
PKD domain DNase I-like 11
Methionine synthase domain Methionine synthase activation domain-like 11
alpha-helical ferredoxin Nucleotide-binding domain 11
DNA ligase/mRNA capping enzyme, catalytic domain RuvA domain 2-like 11
PheT/TilS domain Putative DNA-binding domain 11
NAD(P)-binding Rossmann-fold domains Succinyl-CoA synthetase domains 11
PIN domain-like DNA/RNA polymerases 11
Homodimeric domain of signal transducing histidine kinase Homodimeric domain of signal transducing histidine kinase 11
PK beta-barrel domain-like PK C-terminal domain-like 11
"Winged helix" DNA-binding domain NAD(P)-binding Rossmann-fold domains 11
PRC-barrel domain PRC-barrel domain 11
Hedgehog/intein (Hint) domain Homing endonucleases 11
Sporulation response regulatory protein Spo0B ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase 11
Glucose permease domain IIB Duplicated hybrid motif 11
Coiled-coil domain of nucleotide exchange factor GrpE Head domain of nucleotide exchange factor GrpE 11
Zinc beta-ribbon DNA primase core 11
Phosphoenolpyruvate/pyruvate domain PK C-terminal domain-like 11
Putative DNA-binding domain Putative DNA-binding domain 11
DNA polymerase beta, N-terminal domain-like Nucleotidyltransferase 11
NagB/RpiA/CoA transferase-like 4Fe-4S ferredoxins 11
Folate-binding domain Aminomethyltransferase beta-barrel domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) SIS domain 11
Class II aaRS and biotin synthetases Anticodon-binding domain of PheRS 11
Nucleotidylyl transferase An anticodon-binding domain of class I aminoacyl-tRNA synthetases 11
EspE N-terminal domain-like P-loop containing nucleoside triphosphate hydrolases 11
Cupredoxins Cupredoxins 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) Alpha subunit of glutamate synthase, C-terminal domain 11
(Trans)glycosidases Class I glutamine amidotransferase-like 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) FMN-linked oxidoreductases 11
PYP-like sensor domain (PAS domain) Nucleotide cyclase 11
Tetrapyrrole methylase HemD-like 11
Glutathione synthetase ATP-binding domain-like Phosphoenolpyruvate/pyruvate domain 11
PPK N-terminal domain-like Phospholipase D/nuclease 11
Glutathione synthetase ATP-binding domain-like Phosphohistidine domain 11
PTS system IIB component-like PTS system IIB component-like 11
Class II aaRS and biotin synthetases GAD domain-like 11
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain Pyrimidine nucleoside phosphorylase C-terminal domain 11
Chelatase Precorrin-8X methylmutase CbiC/CobH 11
Creatinase/prolidase N-terminal domain Creatinase/aminopeptidase 11
"Winged helix" DNA-binding domain PLP-dependent transferases 11
Dihydropteroate synthetase-like Cobalamin (vitamin B12)-binding domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase DNA mismatch repair protein MutL 11
Eukaryotic type KH-domain (KH-domain type I) HD-domain/PDEase-like 11
PH0987 N-terminal domain-like Cyclophilin-like 11
NAD(P)-binding Rossmann-fold domains Serine metabolism enzymes domain 11
UbiD C-terminal domain-like UbiD C-terminal domain-like 11
Methylglyoxal synthase-like Cytidine deaminase-like 11
alpha-helical ferredoxin ARM repeat 11
Fe,Mn superoxide dismutase (SOD), N-terminal domain Fe,Mn superoxide dismutase (SOD), C-terminal domain 11
Tetrahydrobiopterin biosynthesis enzymes-like Tetrahydrobiopterin biosynthesis enzymes-like 11
Respiratory nitrate reductase 1 gamma chain alpha-helical ferredoxin 11
RuvA domain 2-like MCP/YpsA-like 11
Obg GTP-binding protein N-terminal domain P-loop containing nucleoside triphosphate hydrolases 11
Galactose-binding domain-like Fibronectin type III 11
FAD-binding/transporter-associated domain-like Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain 11
ADC synthase Class I glutamine amidotransferase-like 11
Formate/glycerate dehydrogenase catalytic domain-like ACT-like 11
PheT/TilS domain Cytidine deaminase-like 11
Adenine nucleotide alpha hydrolases-like DHS-like NAD/FAD-binding domain 11
CO dehydrogenase ISP C-domain like CO dehydrogenase flavoprotein C-terminal domain-like 11
HAMP domain-like Nucleotide cyclase 11
DnaJ/Hsp40 cysteine-rich domain HSP40/DnaJ peptide-binding domain 11
HMA, heavy metal-associated domain Metal cation-transporting ATPase, ATP-binding domain N 11
Class I glutamine amidotransferase-like Class I glutamine amidotransferase-like 11
LysM domain Barwin-like endoglucanases 11
Galactose-binding domain-like Soluble quinoprotein glucose dehydrogenase 11
Elongation factor Ts (EF-Ts), dimerisation domain Elongation factor Ts (EF-Ts), dimerisation domain 11
Sporulation related repeat Sporulation related repeat 11
ThrRS/AlaRS common domain Class II aaRS ABD-related 11
MoeA N-terminal region -like Molybdenum cofactor biosynthesis proteins 11
"Winged helix" DNA-binding domain "Winged helix" DNA-binding domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cytochrome c 11
Ribosomal protein L7/12, oligomerisation (N-terminal) domain ClpS-like 11
DNA repair protein MutS, domain I P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins PheT/TilS domain 11
N-terminal domain of alpha and beta subunits of F1 ATP synthase C-terminal domain of alpha and beta subunits of F1 ATP synthase 11
PK beta-barrel domain-like Phosphoenolpyruvate/pyruvate domain 11
PKD domain Collagen-binding domain 11
Carbamate kinase-like ACT-like 11
FAS1 domain FAS1 domain 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) ThrRS/AlaRS common domain 11
GAF domain-like CheY-like 11
Heat shock protein 70kD (HSP70), peptide-binding domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Rho N-terminal domain-like Nucleic acid-binding proteins 11
HPr-like Phosphoenolpyruvate/pyruvate domain 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), C-terminal subdomain 11
Glutamine synthetase, N-terminal domain Glutamine synthetase/guanido kinase 11
Actin-like ATPase domain Heat shock protein 70kD (HSP70), peptide-binding domain 11
S13-like H2TH domain Glucocorticoid receptor-like (DNA-binding domain) 11
YrdC/RibB RibA-like 11
Nucleotidylyl transferase Nudix 11
Formyltransferase FMT C-terminal domain-like 11
FAD/NAD(P)-binding domain Nitrite and sulphite reductase 4Fe-4S domain-like 11
Molybdenum cofactor biosynthesis proteins CinA-like 11
Clc chloride channel TrkA C-terminal domain-like 11
Nucleotidylyl transferase GatB/YqeY motif 11
Transcription factor NusA, N-terminal domain Nucleic acid-binding proteins 11
Galactose mutarotase-like Six-hairpin glycosidases 11
Metallo-hydrolase/oxidoreductase Rhodanese/Cell cycle control phosphatase 11
Composite domain of metallo-dependent hydrolases Composite domain of metallo-dependent hydrolases 11
Iron-dependent repressor protein, dimerization domain C-terminal domain of transcriptional repressors 11
Phoshotransferase/anion transport protein Phosphohistidine domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like ACT-like 11
Nucleotide-diphospho-sugar transferases Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain 11
HPr-like Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Transmembrane di-heme cytochromes a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) 11
GroEL equatorial domain-like GroEL-intermediate domain like 11
TGS-like Class II aaRS and biotin synthetases 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases tRNA-binding arm 11
Leukotriene A4 hydrolase N-terminal domain Metalloproteases ("zincins"), catalytic domain 11
Periplasmic binding protein-like II Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain 11
Cytochrome c oxidase subunit II-like, transmembrane region Cupredoxins 11
Insert subdomain of RNA polymerase alpha subunit RBP11-like subunits of RNA polymerase 11
MoaD/ThiS Molybdopterin synthase subunit MoaE 11
N-terminal domain of alpha and beta subunits of F1 ATP synthase P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases C-terminal UvrC-binding domain of UvrB 11
ValRS/IleRS/LeuRS editing domain tRNA-binding arm 11
Nqo1 middle domain-like Nqo1C-terminal domain-like 11
2Fe-2S ferredoxin-like ADC-like 11
Carboxypeptidase regulatory domain-like CBD9-like 11
Nucleotidyltransferase TGS-like 11
Obg GTP-binding protein N-terminal domain Obg GTP-binding protein C-terminal domain 11
2Fe-2S ferredoxin-like FAD-binding/transporter-associated domain-like 11
Protease propeptides/inhibitors Subtilisin-like 11
S-adenosylmethionine synthetase S-adenosylmethionine synthetase 11
Nucleotidylyl transferase Nucleic acid-binding proteins 11
4Fe-4S ferredoxins 4Fe-4S ferredoxins 11
Invasin/intimin cell-adhesion fragments Soluble quinoprotein glucose dehydrogenase 11
Transcription factor NusA, N-terminal domain Prokaryotic type KH domain (KH-domain type II) 11
Fe-S cluster assembly (FSCA) domain-like P-loop containing nucleoside triphosphate hydrolases 11
Nucleic acid-binding proteins Putative DNA-binding domain 11
Trigger factor ribosome-binding domain FKBP-like 11
Homocysteine S-methyltransferase Methionine synthase activation domain-like 11
Phoshotransferase/anion transport protein HPr-like 11
PYP-like sensor domain (PAS domain) CheY-like 11
P-loop containing nucleoside triphosphate hydrolases Obg GTP-binding protein C-terminal domain 11
DNA polymerase beta, N-terminal domain-like Sec63 N-terminal domain-like 11
Eukaryotic type KH-domain (KH-domain type I) Nucleic acid-binding proteins 11
DNA repair protein MutS, domain II P-loop containing nucleoside triphosphate hydrolases 11
Invasin/intimin cell-adhesion fragments Metalloproteases ("zincins"), catalytic domain 11
P-loop containing nucleoside triphosphate hydrolases HRDC-like 11
Pre-protein crosslinking domain of SecA Helical scaffold and wing domains of SecA 11
TPR-like Cytochrome c 11
DNA repair protein MutS, domain III SMR domain-like 11
Glutathione synthetase ATP-binding domain-like Succinyl-CoA synthetase domains 11
PLP-dependent transferases PLP-dependent transferases 11
Translation proteins Initiation factor IF2/eIF5b, domain 3 11
HD-domain/PDEase-like TGS-like 11
PUA domain-like Nucleotidylyl transferase 11
NAD(P)-binding Rossmann-fold domains TrkA C-terminal domain-like 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Nucleotidylyl transferase 11
P-loop containing nucleoside triphosphate hydrolases TrpR-like 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
6-phosphogluconate dehydrogenase C-terminal domain-like UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
N-terminal domain of MutM-like DNA repair proteins S13-like H2TH domain 11
Nucleic acid-binding proteins ArfGap/RecO-like zinc finger 11
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases 11
Tubulin nucleotide-binding domain-like Tubulin C-terminal domain-like 11
Aconitase iron-sulfur domain LeuD/IlvD-like 11
Class II aaRS and biotin synthetases C-terminal domain of ProRS 11
CarD-like TRCF domain-like 11
HCP-like TPR-like 11
P-loop containing nucleoside triphosphate hydrolases RecA protein, C-terminal domain 11
ALDH-like Thioesterase/thiol ester dehydrase-isomerase 11
(Trans)glycosidases CBD9-like 11
PreATP-grasp domain Carbamoyl phosphate synthetase, large subunit connection domain 11
CRISPR-associated protein CRISPR-associated protein 11
"Winged helix" DNA-binding domain Ribokinase-like 11
DNA polymerase beta, N-terminal domain-like PHP domain-like 11
Adenine nucleotide alpha hydrolases-like Argininosuccinate synthetase, C-terminal domain 11
PurM N-terminal domain-like PurM N-terminal domain-like 11
Hsp33 domain HSP33 redox switch-like 11
Nqo1 FMN-binding domain-like Nqo1C-terminal domain-like 11
PKD domain Lamin A/C globular tail domain 11
PPK N-terminal domain-like PHP14-like 11
Glycosyl hydrolase domain CBD9-like 11
"Winged helix" DNA-binding domain C-terminal domain of arginine repressor 11
TGS-like Class II aaRS ABD-related 11
Ribosomal protein S5 domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Protein kinase-like (PK-like) P-loop containing nucleoside triphosphate hydrolases 11
"Winged helix" DNA-binding domain Iron-dependent repressor protein, dimerization domain 11
Glutamyl tRNA-reductase catalytic, N-terminal domain NAD(P)-binding Rossmann-fold domains 11
Type II DNA topoisomerase GyrA/ParC C-terminal domain-like 11
DNase I-like Lamin A/C globular tail domain 11
Cupredoxins Cytochrome c 11
Metal cation-transporting ATPase, ATP-binding domain N Calcium ATPase, transmembrane domain M 11
TPR-like HD-domain/PDEase-like 11
PurM C-terminal domain-like PurM C-terminal domain-like 11
Nucleic acid-binding proteins GAD domain-like 11
Protease propeptides/inhibitors Collagen-binding domain 11
N-terminal nucleophile aminohydrolases (Ntn hydrolases) PRTase-like 11
Thioredoxin-like Six-hairpin glycosidases 11
Class I glutamine amidotransferase-like Adenine nucleotide alpha hydrolases-like 11
Nqo1 FMN-binding domain-like Nqo1 middle domain-like 11
2Fe-2S ferredoxin-like CO dehydrogenase flavoprotein C-terminal domain-like 11
N-utilization substance G protein NusG, N-terminal domain Translation proteins SH3-like domain 11
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase Type II DNA topoisomerase 11
lambda repressor-like DNA-binding domains S-adenosyl-L-methionine-dependent methyltransferases 11
Sec63 N-terminal domain-like PHP domain-like 11
Aspartate/glutamate racemase Aspartate/glutamate racemase 11
Cytidine deaminase-like Dihydrofolate reductase-like 11
Methionine synthase domain Cobalamin (vitamin B12)-binding domain 11
Putative DNA-binding domain Class II aaRS and biotin synthetases 11
AraD/HMP-PK domain-like NAD(P)-binding Rossmann-fold domains 11
Molybdenum cofactor biosynthesis proteins MoeA C-terminal domain-like 11
PHP domain-like AF1531-like 11
Chaperone J-domain DnaJ/Hsp40 cysteine-rich domain 11
DNA repair protein MutS, domain I DNA repair protein MutS, domain III 11
Phoshotransferase/anion transport protein Phosphoenolpyruvate/pyruvate domain 11
N-terminal domain of MutM-like DNA repair proteins Glucocorticoid receptor-like (DNA-binding domain) 11
GroEL equatorial domain-like GroEL apical domain-like 11
TGS-like ThrRS/AlaRS common domain 11
PheT/TilS domain Class II aaRS and biotin synthetases 11
C-terminal UvrC-binding domain of UvrB RuvA domain 2-like 11
Homocysteine S-methyltransferase Dihydropteroate synthetase-like 11
FabD/lysophospholipase-like Probable ACP-binding domain of malonyl-CoA ACP transacylase 11
DNA ligase/mRNA capping enzyme, catalytic domain BRCT domain 11
TPR-like Nucleotide cyclase 11
dsRNA-binding domain-like Ribosomal protein S5 domain 2-like 11
5' to 3' exonuclease, C-terminal subdomain DNA/RNA polymerases 11
ACT-like Formyltransferase 11
DNA topoisomerase I domain DNA breaking-rejoining enzymes 11
HD-domain/PDEase-like Nucleotidyltransferase 11
Invasin/intimin cell-adhesion fragments PR-1-like 11
beta-N-acetylhexosaminidase-like domain (Trans)glycosidases 11
P-loop containing nucleoside triphosphate hydrolases Isocitrate/Isopropylmalate dehydrogenase-like 11
Ribosomal protein S5 domain 2-like Nucleic acid-binding proteins 11
CheY-like "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases TRCF domain-like 11
Ribosomal protein S5 domain 2-like DNA mismatch repair protein MutL 11
Class II aaRS ABD-related C-terminal domain of ProRS 11
P-loop containing nucleoside triphosphate hydrolases MOP-like 11
Cobalamin (vitamin B12)-binding domain Methionine synthase activation domain-like 11
Translation proteins Translation proteins 11
Protein kinase-like (PK-like) Quinoprotein alcohol dehydrogenase-like 11
Homocysteine S-methyltransferase Methionine synthase domain 11
PA domain Subtilisin-like 11
PUA domain-like alpha/beta knot 11
Nucleotidyltransferase ACT-like 11
Nucleotidylyl transferase Ribosomal protein L25-like 11
HPr-like Phosphohistidine domain 11
P-loop containing nucleoside triphosphate hydrolases HprK N-terminal domain-like 11
PIN domain-like Ribonuclease H-like 11
PKD domain PKD domain 11
2Fe-2S ferredoxin-like alpha-helical ferredoxin 11
YefM-like P-loop containing nucleoside triphosphate hydrolases 11
Class II aaRS and biotin synthetases C-terminal domain of transcriptional repressors 11
NAD(P)-binding Rossmann-fold domains Siroheme synthase middle domains-like 11
Penicillin binding protein dimerisation domain beta-lactamase/transpeptidase-like 11
Galactose-binding domain-like Kelch motif 11
P-loop containing nucleoside triphosphate hydrolases TGS-like 11
Cytochrome c Cytochrome c 11
Chorismate mutase II Aldolase 11
Eukaryotic type KH-domain (KH-domain type I) P-loop containing nucleoside triphosphate hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Initiation factor IF2/eIF5b, domain 3 11
NusB-like S-adenosyl-L-methionine-dependent methyltransferases 11
Ribonuclease H-like DNA/RNA polymerases 11
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Nucleotidylyl transferase Alpha-L RNA-binding motif 11
Class I glutamine amidotransferase-like GMP synthetase C-terminal dimerisation domain 11
Insert subdomain of RNA polymerase alpha subunit C-terminal domain of RNA polymerase alpha subunit 11
GatB/YqeY motif GatB/YqeY motif 11
DeoB insert domain-like Alkaline phosphatase-like 11
RuvA domain 2-like DNA helicase RuvA subunit, C-terminal domain 11
Prokaryotic type KH domain (KH-domain type II) Prokaryotic type KH domain (KH-domain type II) 11
Calcium ATPase, transduction domain A Metal cation-transporting ATPase, ATP-binding domain N 11
FMN-linked oxidoreductases Alpha subunit of glutamate synthase, C-terminal domain 11
UBA-like Elongation factor Ts (EF-Ts), dimerisation domain 11
alpha/beta-Hydrolases AhpD-like 11
NAD(P)-binding Rossmann-fold domains 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain 11
Mechanosensitive channel protein MscS (YggB), transmembrane region Sm-like ribonucleoproteins 11
Ribosomal protein S5 domain 2-like Type II DNA topoisomerase 11
HprK N-terminal domain-like Isocitrate/Isopropylmalate dehydrogenase-like 11
Class II aaRS and biotin synthetases Translation proteins 11
Nucleic acid-binding proteins S-adenosyl-L-methionine-dependent methyltransferases 11
Cobalamin (vitamin B12)-dependent enzymes Cobalamin (vitamin B12)-binding domain 11
Phoshotransferase/anion transport protein Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain 11
Ribosomal L11/L12e N-terminal domain Ribosomal protein L11, C-terminal domain 11
GIY-YIG endonuclease RuvA domain 2-like 11
N-terminal domain of DnaB helicase Homing endonucleases 11
PreATP-grasp domain PreATP-grasp domain 11
Triger factor/SurA peptide-binding domain-like Triger factor/SurA peptide-binding domain-like 11
N-terminal domain of DnaB helicase P-loop containing nucleoside triphosphate hydrolases 11
L9 N-domain-like Ribosomal protein L9 C-domain 11
Nudix "Winged helix" DNA-binding domain 11
P-loop containing nucleoside triphosphate hydrolases Signal peptide-binding domain 11
S-adenosyl-L-methionine-dependent methyltransferases P-loop containing nucleoside triphosphate hydrolases 11
DPP6 N-terminal domain-like alpha/beta-Hydrolases 11
P-loop containing nucleoside triphosphate hydrolases Homing endonucleases 11
Protein kinase-like (PK-like) NHL repeat 11
Glutamine synthetase/guanido kinase GatB/YqeY motif 11
Ribosomal protein L6 Ribosomal protein L6 11
Cytochrome c Quinoprotein alcohol dehydrogenase-like 11
P-loop containing nucleoside triphosphate hydrolases Prokaryotic type KH domain (KH-domain type II) 11
PKD domain PR-1-like 11
RBP11-like subunits of RNA polymerase C-terminal domain of RNA polymerase alpha subunit 11
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases Nucleic acid-binding proteins 11
P-loop containing nucleoside triphosphate hydrolases Smc hinge domain 11
P-loop containing nucleoside triphosphate hydrolases vWA-like 11
Carbamoyl phosphate synthetase, small subunit N-terminal domain Class I glutamine amidotransferase-like 11
Nucleic acid-binding proteins Prokaryotic type KH domain (KH-domain type II) 11
Quinoprotein alcohol dehydrogenase-like Quinoprotein alcohol dehydrogenase-like 11
N-terminal domain of DnaB helicase Hedgehog/intein (Hint) domain 11
Xylose isomerase-like Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase 11
P-loop containing nucleoside triphosphate hydrolases MetI-like 11
DNA repair protein MutS, domain II DNA repair protein MutS, domain III 11
GroEL-intermediate domain like GroEL apical domain-like 11
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) Translation proteins 11
C-terminal effector domain of the bipartite response regulators TPR-like 11
Glutathione synthetase ATP-binding domain-like Glutathione synthetase ATP-binding domain-like 11
Dihydropteroate synthetase-like Methionine synthase domain 11
Trigger factor ribosome-binding domain Triger factor/SurA peptide-binding domain-like 11
CO dehydrogenase ISP C-domain like FAD-binding/transporter-associated domain-like 11
Sec63 N-terminal domain-like Nucleotidyltransferase 11
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD CoaB-like 11
FMN-binding split barrel UbiD C-terminal domain-like 11
DNA ligase/mRNA capping enzyme, catalytic domain Nucleic acid-binding proteins 11
CBS-domain pair Inosine monophosphate dehydrogenase (IMPDH) 11
Galactose-binding domain-like Galactose oxidase, central domain 11
Ribonuclease PH domain 2-like Eukaryotic type KH-domain (KH-domain type I) 11
Domain of the SRP/SRP receptor G-proteins P-loop containing nucleoside triphosphate hydrolases 11
Subtilisin-like Collagen-binding domain 11
Sm-like ribonucleoproteins Mechanosensitive channel protein MscS (YggB), C-terminal domain 11
HisI-like all-alpha NTP pyrophosphatases 11
(Trans)glycosidases NAD(P)-binding Rossmann-fold domains 11
Aldolase 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain 11
5' to 3' exonuclease, C-terminal subdomain Ribonuclease H-like 11
P-loop containing nucleoside triphosphate hydrolases Hedgehog/intein (Hint) domain 11
Carbamate kinase-like PUA domain-like 11
PLP-dependent transferases HRDC-like 11
Nitrite/Sulfite reductase N-terminal domain-like Nitrite/Sulfite reductase N-terminal domain-like 11
NAD(P)-binding Rossmann-fold domains UDP-glucose/GDP-mannose dehydrogenase C-terminal domain 11
Putative DNA-binding domain Anticodon-binding domain of PheRS 11
Ribonuclease PH domain 2-like Ribonuclease PH domain 2-like 11
P-loop containing nucleoside triphosphate hydrolases Pre-protein crosslinking domain of SecA 11
4Fe-4S ferredoxins ADC-like 11
(Trans)glycosidases Carboxypeptidase regulatory domain-like 11
Single hybrid motif Single hybrid motif 11
HIT-like HIT-like 11
Metal cation-transporting ATPase, ATP-binding domain N HAD-like 11
PIN domain-like 5' to 3' exonuclease, C-terminal subdomain 11
Nucleic acid-binding proteins Anticodon-binding domain of PheRS 11
Ribonuclease PH domain 2-like Nucleic acid-binding proteins 11
PheT/TilS domain Anticodon-binding domain of PheRS 11
Nucleic acid-binding proteins BRCT domain 11
Formate/glycerate dehydrogenase catalytic domain-like Serine metabolism enzymes domain 11
Nucleotidylyl transferase Riboflavin kinase-like 11
MoeA N-terminal region -like MoeA C-terminal domain-like 11
Adenine nucleotide alpha hydrolases-like Cytidine deaminase-like 11
NagB/RpiA/CoA transferase-like NagB/RpiA/CoA transferase-like 11
P-loop containing nucleoside triphosphate hydrolases CarD-like 11
Cytochrome c oxidase subunit I-like Cytochrome c oxidase subunit III-like 11
lambda repressor-like DNA-binding domains LexA/Signal peptidase 11
IlvD/EDD N-terminal domain-like LeuD/IlvD-like 11
Fibronectin type III CBD9-like 11
PDZ domain-like Radical SAM enzymes 11
PHP14-like Phospholipase D/nuclease 11
S-adenosyl-L-methionine-dependent methyltransferases Putative methyltransferase TM0872, insert domain 11
PEP carboxykinase N-terminal domain PEP carboxykinase-like 11
Nucleotidyltransferase PHP domain-like 11

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