All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
Homeodomain-like | Homeodomain-like | 149 | 13 | |
Regulatory protein AraC | Homeodomain-like | 66 | 6 | |
HAMP domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 64 | 6 | |
Homodimeric domain of signal transducing histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 61 | 28 | |
CheY-like | Homeodomain-like | 60 | 4 | |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 44 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 42 | 12 | |
CheY-like | C-terminal effector domain of the bipartite response regulators | 38 | 3 | |
"Winged helix" DNA-binding domain | Periplasmic binding protein-like II | 37 | 2 | |
CoA-dependent acyltransferases | Acetyl-CoA synthetase-like | 35 | 29 | |
Acetyl-CoA synthetase-like | ACP-like | 35 | 29 | |
CoA-dependent acyltransferases | ACP-like | 35 | 29 | |
Homeodomain-like | Tetracyclin repressor-like, C-terminal domain | 34 | 1 | |
CoA-dependent acyltransferases | CoA-dependent acyltransferases | 34 | 28 | |
(Trans)glycosidases | Galactose-binding domain-like | 32 | 24 | |
ACP-like | ACP-like | 29 | 27 | |
Acetyl-CoA synthetase-like | Acetyl-CoA synthetase-like | 26 | 24 | |
Sigma2 domain of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 26 | 4 | |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 25 | 2 | |
(Trans)glycosidases | Glycosyl hydrolase domain | 23 | 12 | |
GroES-like | NAD(P)-binding Rossmann-fold domains | 21 | 1 | |
lambda repressor-like DNA-binding domains | Periplasmic binding protein-like I | 21 | 1 | |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 19 | 6 | |
Arabinanase/levansucrase/invertase | Concanavalin A-like lectins/glucanases | 18 | 7 | |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 18 | 3 | |
Galactose-binding domain-like | Galactose-binding domain-like | 18 | 18 | |
HAMP domain-like | Homodimeric domain of signal transducing histidine kinase | 18 | 4 | |
PYP-like sensor domain (PAS domain) | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 17 | 12 | |
Fibronectin type III | Fibronectin type III | 17 | 17 | |
Actin-like ATPase domain | Actin-like ATPase domain | 16 | 5 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | CheY-like | 16 | 15 | |
PYP-like sensor domain (PAS domain) | PYP-like sensor domain (PAS domain) | 16 | 13 | |
Nucleotide cyclase | EAL domain-like | 15 | 5 | |
PYP-like sensor domain (PAS domain) | Nucleotide cyclase | 15 | 9 | |
Galactose-binding domain-like | beta-Galactosidase/glucuronidase domain | 15 | 8 | |
beta-Galactosidase/glucuronidase domain | (Trans)glycosidases | 15 | 8 | |
PYP-like sensor domain (PAS domain) | Homodimeric domain of signal transducing histidine kinase | 14 | 10 | |
Composite domain of metallo-dependent hydrolases | Metallo-dependent hydrolases | 14 | 4 | |
Homodimeric domain of signal transducing histidine kinase | CheY-like | 14 | 13 | |
ACP-like | alpha/beta-Hydrolases | 12 | 10 | |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 11 | 4 | |
Zn-dependent exopeptidases | Bacterial exopeptidase dimerisation domain | 11 | 1 | |
CoA-dependent acyltransferases | alpha/beta-Hydrolases | 11 | 9 | |
Acetyl-CoA synthetase-like | alpha/beta-Hydrolases | 11 | 9 | |
"Winged helix" DNA-binding domain | NagB/RpiA/CoA transferase-like | 10 | 1 | |
"Winged helix" DNA-binding domain | PLP-dependent transferases | 10 | 1 | |
Fibronectin type III | Carbohydrate-binding domain | 10 | 9 | |
Fibronectin type III | (Trans)glycosidases | 10 | 10 | |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 9 | 2 | |
Thiolase-like | Thiolase-like | 9 | 4 | |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 9 | 5 | |
Fibronectin type III | Type I dockerin domain | 9 | 7 | |
Sensory domain-like | Methyl-accepting chemotaxis protein (MCP) signaling domain | 9 | 2 | |
"Winged helix" DNA-binding domain | GntR ligand-binding domain-like | 8 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | MOP-like | 8 | 2 | |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 8 | 6 | |
PYP-like sensor domain (PAS domain) | EAL domain-like | 8 | 3 | |
FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 8 | 3 | |
Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 8 | 2 | |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 8 | 4 | |
Thiamin diphosphate-binding fold (THDP-binding) | DHS-like NAD/FAD-binding domain | 7 | 1 | |
beta-Roll | beta-Roll | 7 | 2 | |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 7 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 7 | 5 | |
GAF domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 7 | 7 | |
cAMP-binding domain-like | "Winged helix" DNA-binding domain | 7 | 1 | |
ACP-like | Thiolase-like | 7 | 6 | |
Galactose mutarotase-like | (Trans)glycosidases | 7 | 5 | |
Galactose-binding domain-like | SGNH hydrolase | 7 | 5 | |
NAD(P)-binding Rossmann-fold domains | ACP-like | 7 | 6 | |
GAF domain-like | Homodimeric domain of signal transducing histidine kinase | 6 | 6 | |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 6 | 4 | |
MalF N-terminal region-like | MetI-like | 6 | 2 | |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 6 | 2 | |
Fibronectin type III | Pectin lyase-like | 6 | 6 | |
Trypsin-like serine proteases | PDZ domain-like | 6 | 4 | |
NAD(P)-binding Rossmann-fold domains | Thiolase-like | 6 | 5 | |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 6 | 4 | |
Fibronectin type III | Six-hairpin glycosidases | 6 | 5 | |
(Trans)glycosidases | Beta-D-glucan exohydrolase, C-terminal domain | 6 | 4 | |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 6 | 2 | |
E set domains | (Trans)glycosidases | 6 | 6 | |
Multidrug efflux transporter AcrB transmembrane domain | Multidrug efflux transporter AcrB transmembrane domain | 5 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 5 | 3 | |
Pectin lyase-like | Pectin lyase-like | 5 | 4 | |
Phospholipase D/nuclease | Phospholipase D/nuclease | 5 | 2 | |
Translation proteins | EF-G C-terminal domain-like | 5 | 3 | |
Penicillin binding protein dimerisation domain | beta-lactamase/transpeptidase-like | 5 | 3 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 5 | 2 | |
Metallo-dependent phosphatases | 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 5 | 4 | |
CheY-like | CheY-like | 5 | 5 | |
Carbohydrate-binding domain | Type I dockerin domain | 5 | 4 | |
"Winged helix" DNA-binding domain | Dimeric alpha+beta barrel | 5 | 1 | |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 5 | 2 | |
(Trans)glycosidases | Class I glutamine amidotransferase-like | 5 | 1 | |
MurD-like peptide ligases, catalytic domain | MurD-like peptide ligases, peptide-binding domain | 5 | 3 | |
PreATP-grasp domain | Rudiment single hybrid motif | 5 | 2 | |
Formate dehydrogenase/DMSO reductase, domains 1-3 | ADC-like | 5 | 1 | |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | Sigma3 and sigma4 domains of RNA polymerase sigma factors | 5 | 1 | |
Lysozyme-like | beta-lactamase/transpeptidase-like | 5 | 3 | |
Nucleotide-diphospho-sugar transferases | Trimeric LpxA-like enzymes | 5 | 2 | |
Nitrite/Sulfite reductase N-terminal domain-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 5 | 3 | |
NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 5 | 4 | |
Sigma2 domain of RNA polymerase sigma factors | NTF2-like | 5 | 1 | |
Homeodomain-like | Probable bacterial effector-binding domain | 5 | 1 | |
FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 5 | 2 | |
Galactose-binding domain-like | Fibronectin type III | 5 | 5 | |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | NTF2-like | 5 | 1 | |
Alpha-L RNA-binding motif | Pseudouridine synthase | 5 | 1 | |
beta-Galactosidase/glucuronidase domain | beta-Galactosidase/glucuronidase domain | 5 | 3 | |
Sporulation response regulatory protein Spo0B | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 5 | 3 | |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 5 | 2 | |
ACP-like | S-adenosyl-L-methionine-dependent methyltransferases | 4 | 4 | |
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | Multidrug efflux transporter AcrB transmembrane domain | 4 | 1 | |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 4 | 1 | |
Galactose-binding domain-like | Galactose mutarotase-like | 4 | 4 | |
Phosphoenolpyruvate/pyruvate domain | Phosphohistidine domain | 4 | 3 | |
(Trans)glycosidases | CBD9-like | 4 | 4 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Oligoxyloglucan reducing end-specific cellobiohydrolase | 4 | 4 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | 4 | 1 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB transmembrane domain | 4 | 1 | |
"Winged helix" DNA-binding domain | Actin-like ATPase domain | 4 | 2 | |
beta-lactamase/transpeptidase-like | Penicillin-binding protein associated domain | 4 | 1 | |
GAF domain-like | CheY-like | 4 | 4 | |
Bacillus cereus metalloprotein-like | Bacillus cereus metalloprotein-like | 4 | 2 | |
RmlC-like cupins | Homeodomain-like | 4 | 2 | |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 4 | 2 | |
Thiolase-like | FabD/lysophospholipase-like | 4 | 3 | |
(Trans)glycosidases | Carbohydrate-binding domain | 4 | 4 | |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 4 | 3 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 4 | 3 | |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 4 | 2 | |
Carbohydrate binding domain | Fibronectin type III | 4 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | TPR-like | 4 | 3 | |
CBS-domain pair | FAD-binding/transporter-associated domain-like | 4 | 1 | |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | 4 | 2 | |
ACT-like | ACT-like | 4 | 2 | |
ValRS/IleRS/LeuRS editing domain | Nucleotidylyl transferase | 4 | 3 | |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | S-adenosyl-L-methionine-dependent methyltransferases | 4 | 2 | |
PurM N-terminal domain-like | PurM C-terminal domain-like | 4 | 3 | |
Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | 4 | 4 | |
Galactose mutarotase-like | Glycosyl hydrolase domain | 4 | 2 | |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 4 | 3 | |
FabD/lysophospholipase-like | ACP-like | 4 | 3 | |
PYP-like sensor domain (PAS domain) | P-loop containing nucleoside triphosphate hydrolases | 4 | 4 | |
Calcium ATPase, transduction domain A | HAD-like | 4 | 4 | |
Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | Multidrug efflux transporter AcrB TolC docking domain; DN and DC subdomains | 4 | 1 | |
HlyD-like secretion proteins | HlyD-like secretion proteins | 4 | 3 | |
PYP-like sensor domain (PAS domain) | CheY-like | 4 | 4 | |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 4 | 4 | |
HAD-like | Calcium ATPase, transmembrane domain M | 4 | 4 | |
Arabinanase/levansucrase/invertase | AbfB domain | 4 | 3 | |
Triger factor/SurA peptide-binding domain-like | FKBP-like | 4 | 4 | |
FAD/NAD(P)-binding domain | Nitrite and sulphite reductase 4Fe-4S domain-like | 4 | 2 | |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 4 | 4 | |
FAD/NAD(P)-binding domain | Nitrite/Sulfite reductase N-terminal domain-like | 4 | 2 | |
lambda repressor-like DNA-binding domains | RmlC-like cupins | 4 | 1 | |
Copper amine oxidase, domain N | Copper amine oxidase, domain N | 4 | 4 | |
Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains | 4 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal effector domain of the bipartite response regulators | 4 | 2 | |
Galactose-binding domain-like | CBD9-like | 3 | 3 | |
Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 3 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 3 | 2 | |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
HMA, heavy metal-associated domain | HAD-like | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 3 | 2 | |
NAD(P)-binding Rossmann-fold domains | ACT-like | 3 | 3 | |
NAD(P)-binding Rossmann-fold domains | TrkA C-terminal domain-like | 3 | 1 | |
ThrRS/AlaRS common domain | Class II aaRS and biotin synthetases | 3 | 2 | |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 3 | 1 | |
HAMP domain-like | Nucleotide cyclase | 3 | 2 | |
DNA repair protein MutS, domain III | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
GroEL equatorial domain-like | GroEL apical domain-like | 3 | 2 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | NAD(P)-binding Rossmann-fold domains | 3 | 2 | |
Aldolase | 2-isopropylmalate synthase LeuA, allosteric (dimerisation) domain | 3 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Homeodomain-like | 3 | 3 | |
Invasin/intimin cell-adhesion fragments | Fibronectin type III | 3 | 3 | |
SH3-domain | Cysteine proteinases | 3 | 2 | |
Acetyl-CoA synthetase-like | S-adenosyl-L-methionine-dependent methyltransferases | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 3 | 2 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Adenine nucleotide alpha hydrolases-like | 3 | 1 | |
Sensory domain-like | Nucleotide cyclase | 3 | 3 | |
"Winged helix" DNA-binding domain | CBS-domain pair | 3 | 2 | |
Arabinanase/levansucrase/invertase | Invasin/intimin cell-adhesion fragments | 3 | 3 | |
PDZ domain-like | ClpP/crotonase | 3 | 3 | |
Pentapeptide repeat-like | Pentapeptide repeat-like | 3 | 2 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | ACP-like | 3 | 2 | |
Galactose-binding domain-like | Glycosyl hydrolase domain | 3 | 3 | |
Arabinanase/levansucrase/invertase | Ricin B-like lectins | 3 | 2 | |
FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 3 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transduction domain A | 3 | 3 | |
MFS general substrate transporter | MFS general substrate transporter | 3 | 2 | |
Tricorn protease N-terminal domain | Fibronectin type III | 3 | 3 | |
Galactose-binding domain-like | Invasin/intimin cell-adhesion fragments | 3 | 3 | |
(Trans)glycosidases | Invasin/intimin cell-adhesion fragments | 3 | 3 | |
tRNA-binding arm | Class II aaRS and biotin synthetases | 3 | 1 | |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 3 | 2 | |
Nucleotidyltransferase | PAP/OAS1 substrate-binding domain | 3 | 1 | |
Chondroitin AC/alginate lyase | Hyaluronate lyase-like, C-terminal domain | 3 | 3 | |
beta-Galactosidase/glucuronidase domain | Galactose mutarotase-like | 3 | 3 | |
PYP-like sensor domain (PAS domain) | Homeodomain-like | 3 | 3 | |
Sensory domain-like | PYP-like sensor domain (PAS domain) | 3 | 2 | |
Carbohydrate binding domain | (Trans)glycosidases | 3 | 3 | |
Sensory domain-like | Sporulation response regulatory protein Spo0B | 3 | 2 | |
Sensory domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 3 | 2 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 3 | 3 | |
CBS-domain pair | Inosine monophosphate dehydrogenase (IMPDH) | 3 | 1 | |
CoA-dependent acyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 3 | 3 | |
Pectin lyase-like | Galactose-binding domain-like | 3 | 3 | |
Galactose-binding domain-like | Six-hairpin glycosidases | 3 | 2 | |
Chondroitin AC/alginate lyase | Galactose mutarotase-like | 3 | 3 | |
"Winged helix" DNA-binding domain | GAF domain-like | 3 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transmembrane domain M | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | "Winged helix" DNA-binding domain | 3 | 3 | |
DPP6 N-terminal domain-like | Fibronectin type III | 3 | 2 | |
Galactose mutarotase-like | Hyaluronate lyase-like, C-terminal domain | 3 | 3 | |
Thiolase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 3 | 2 | |
Nucleic acid-binding proteins | RuvA domain 2-like | 3 | 3 | |
Beta-D-glucan exohydrolase, C-terminal domain | Galactose-binding domain-like | 3 | 2 | |
FabD/lysophospholipase-like | NAD(P)-binding Rossmann-fold domains | 3 | 2 | |
E set domains | Glycosyl hydrolase domain | 3 | 3 | |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 3 | 1 | |
LysM domain | LysM domain | 3 | 3 | |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 3 | 3 | |
Fibronectin type III | E set domains | 3 | 3 | |
Protein kinase-like (PK-like) | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
NHL repeat | Copper amine oxidase, domain N | 2 | 2 | |
LysM domain | Duplicated hybrid motif | 2 | 1 | |
RCC1/BLIP-II | RCC1/BLIP-II | 2 | 1 | |
FMN-linked oxidoreductases | Alpha subunit of glutamate synthase, C-terminal domain | 2 | 2 | |
"Winged helix" DNA-binding domain | Bet v1-like | 2 | 1 | |
HprK N-terminal domain-like | PEP carboxykinase-like | 2 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | E set domains | 2 | 2 | |
DNA clamp | DNA clamp | 2 | 1 | |
Acetyl-CoA synthetase-like | FMN-dependent nitroreductase-like | 2 | 2 | |
Nucleotide-diphospho-sugar transferases | UDP-Glycosyltransferase/glycogen phosphorylase | 2 | 1 | |
Carbamate kinase-like | ACT-like | 2 | 1 | |
ACP-like | FMN-dependent nitroreductase-like | 2 | 2 | |
Pre-protein crosslinking domain of SecA | Helical scaffold and wing domains of SecA | 2 | 2 | |
Methylated DNA-protein cysteine methyltransferase domain | Methylated DNA-protein cysteine methyltransferase, C-terminal domain | 2 | 1 | |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 2 | 1 | |
MurE/MurF N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 2 | 1 | |
Galactose-binding domain-like | E set domains | 2 | 2 | |
Histidine-containing phosphotransfer domain, HPT domain | Homodimeric domain of signal transducing histidine kinase | 2 | 2 | |
Integrin alpha N-terminal domain | E set domains | 2 | 2 | |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 2 | 1 | |
Copper amine oxidase, domain N | Cysteine proteinases | 2 | 2 | |
Tricorn protease N-terminal domain | Type I dockerin domain | 2 | 2 | |
N-utilization substance G protein NusG, N-terminal domain | Translation proteins SH3-like domain | 2 | 2 | |
Invasin/intimin cell-adhesion fragments | Invasin/intimin cell-adhesion fragments | 2 | 2 | |
HprK N-terminal domain-like | CBS-domain pair | 2 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 2 | 1 | |
CheY-like | Histidine-containing phosphotransfer domain, HPT domain | 2 | 2 | |
"Winged helix" DNA-binding domain | HprK N-terminal domain-like | 2 | 1 | |
Arabinanase/levansucrase/invertase | Galactose-binding domain-like | 2 | 2 | |
Serine metabolism enzymes domain | ACT-like | 2 | 2 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 | |
CorA soluble domain-like | Magnesium transport protein CorA, transmembrane region | 2 | 1 | |
RCC1/BLIP-II | Fibronectin type III | 2 | 2 | |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 2 | 1 | |
MurE/MurF N-terminal domain | MurD-like peptide ligases, catalytic domain | 2 | 1 | |
Cupredoxins | Cupredoxins | 2 | 1 | |
GAF domain-like | Methyl-accepting chemotaxis protein (MCP) signaling domain | 2 | 2 | |
NAD(P)-binding Rossmann-fold domains | alpha/beta-Hydrolases | 2 | 2 | |
RuBisCO, large subunit, small (N-terminal) domain | RuBisCo, C-terminal domain | 2 | 1 | |
Galactose mutarotase-like | Putative glucosidase YicI, C-terminal domain | 2 | 1 | |
Nucleotidylyl transferase | An anticodon-binding domain of class I aminoacyl-tRNA synthetases | 2 | 1 | |
DPP6 N-terminal domain-like | Type I dockerin domain | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Glucocorticoid receptor-like (DNA-binding domain) | 2 | 2 | |
ParB/Sulfiredoxin | KorB DNA-binding domain-like | 2 | 1 | |
PLP-dependent transferases | Ornithine decarboxylase C-terminal domain | 2 | 1 | |
Penicillin binding protein dimerisation domain | Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 2 | 2 | |
TGS-like | ThrRS/AlaRS common domain | 2 | 1 | |
Fibronectin type III | SGNH hydrolase | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 2 | 1 | |
Flavoproteins | Ferredoxin reductase-like, C-terminal NADP-linked domain | 2 | 2 | |
NAD(P)-binding Rossmann-fold domains | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 2 | 1 | |
GroEL-intermediate domain like | GroEL apical domain-like | 2 | 1 | |
GAF domain-like | PYP-like sensor domain (PAS domain) | 2 | 2 | |
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | Phosphohistidine domain | 2 | 1 | |
TGS-like | Class II aaRS and biotin synthetases | 2 | 1 | |
PH0987 N-terminal domain-like | Cyclophilin-like | 2 | 2 | |
MurCD N-terminal domain | MurD-like peptide ligases, peptide-binding domain | 2 | 1 | |
GroEL equatorial domain-like | GroEL-intermediate domain like | 2 | 1 | |
Glycosyl hydrolase domain | Fibronectin type III | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Helical scaffold and wing domains of SecA | 2 | 2 | |
Concanavalin A-like lectins/glucanases | Galactose-binding domain-like | 2 | 2 | |
TPR-like | C-terminal effector domain of the bipartite response regulators | 2 | 1 | |
N-terminal domain of MutM-like DNA repair proteins | Glucocorticoid receptor-like (DNA-binding domain) | 2 | 1 | |
PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 2 | 2 | |
GreA transcript cleavage protein, N-terminal domain | FKBP-like | 2 | 1 | |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 2 | 1 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 2 | 1 | |
CBS-domain pair | Thioesterase/thiol ester dehydrase-isomerase | 2 | 1 | |
(Trans)glycosidases | Putative glucosidase YicI, C-terminal domain | 2 | 1 | |
Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 2 | 2 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 2 | 1 | |
Fibronectin type III | Integrin alpha N-terminal domain | 2 | 2 | |
CheC-like | Surface presentation of antigens (SPOA) | 2 | 2 | |
Concanavalin A-like lectins/glucanases | Invasin/intimin cell-adhesion fragments | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Hypothetical protein YjiA, C-terminal domain | 2 | 1 | |
Glycoside hydrolase/deacetylase | Galactose-binding domain-like | 2 | 2 | |
PYP-like sensor domain (PAS domain) | Sporulation response regulatory protein Spo0B | 2 | 1 | |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 2 | 2 | |
Hedgehog/DD-peptidase | PGBD-like | 2 | 2 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | Homodimeric domain of signal transducing histidine kinase | 2 | 2 | |
GIY-YIG endonuclease | C-terminal UvrC-binding domain of UvrB | 2 | 2 | |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Pre-protein crosslinking domain of SecA | 2 | 2 | |
HlyD-like secretion proteins | Single hybrid motif | 2 | 1 | |
SacY-like RNA-binding domain | PTS-regulatory domain, PRD | 2 | 1 | |
"Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 2 | 2 | |
TGS-like | Class II aaRS ABD-related | 2 | 1 | |
IlvD/EDD N-terminal domain-like | LeuD/IlvD-like | 2 | 1 | |
Glutamine synthetase, N-terminal domain | Glutamine synthetase/guanido kinase | 2 | 1 | |
Glycoside hydrolase/deacetylase | Families 57/38 glycoside transferase middle domain | 2 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 | |
Cytochrome c oxidase subunit II-like, transmembrane region | Cupredoxins | 2 | 2 | |
Histidine-containing phosphotransfer domain, HPT domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
beta-lactamase/transpeptidase-like | Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 2 | 2 | |
Flavoproteins | Riboflavin synthase domain-like | 2 | 2 | |
Glucose permease domain IIB | Duplicated hybrid motif | 2 | 1 | |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 2 | 2 | |
"Winged helix" DNA-binding domain | Thioesterase/thiol ester dehydrase-isomerase | 2 | 1 | |
(Trans)glycosidases | (Trans)glycosidases | 2 | 2 | |
HAMP domain-like | PYP-like sensor domain (PAS domain) | 2 | 1 | |
Galactose-binding domain-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
Glycosyl hydrolase domain | Putative glucosidase YicI, C-terminal domain | 2 | 1 | |
Chondroitin AC/alginate lyase | Galactose-binding domain-like | 2 | 2 | |
HprK N-terminal domain-like | Thioesterase/thiol ester dehydrase-isomerase | 2 | 1 | |
4'-phosphopantetheinyl transferase | 4'-phosphopantetheinyl transferase | 2 | 1 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 2 | 1 | |
FucI/AraA N-terminal and middle domains | FucI/AraA C-terminal domain-like | 2 | 1 | |
Galactose-binding domain-like | Homodimeric domain of signal transducing histidine kinase | 2 | 2 | |
DnaK suppressor protein DksA, alpha-hairpin domain | Glucocorticoid receptor-like (DNA-binding domain) | 2 | 1 | |
Type II DNA topoisomerase | GyrA/ParC C-terminal domain-like | 2 | 1 | |
MurCD N-terminal domain | MurD-like peptide ligases, catalytic domain | 2 | 1 | |
Nucleic acid-binding proteins | Ribonuclease H-like | 2 | 2 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | FMN-linked oxidoreductases | 2 | 2 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | CheY-like | 2 | 2 | |
N-terminal domain of MutM-like DNA repair proteins | S13-like H2TH domain | 2 | 1 | |
MetI-like | MetI-like | 2 | 1 | |
Translation initiation factor IF3, N-terminal domain | Translation initiation factor IF3, C-terminal domain | 2 | 1 | |
Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain | Phosphoenolpyruvate/pyruvate domain | 2 | 1 | |
E set domains | Invasin/intimin cell-adhesion fragments | 2 | 2 | |
"Winged helix" DNA-binding domain | Periplasmic binding protein-like I | 2 | 1 | |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 2 | 2 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Alpha subunit of glutamate synthase, C-terminal domain | 2 | 2 | |
Fibronectin type III | Starch-binding domain-like | 2 | 2 | |
Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain | 2 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 2 | 1 | |
Putative DNA-binding domain | Periplasmic binding protein-like II | 2 | 1 | |
L30e-like | alpha/beta knot | 2 | 1 | |
CoA-dependent acyltransferases | FMN-dependent nitroreductase-like | 2 | 2 | |
Rhodanese/Cell cycle control phosphatase | Rhodanese/Cell cycle control phosphatase | 2 | 1 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 2 | 2 | |
GAF domain-like | Nucleotide cyclase | 2 | 2 | |
Ada DNA repair protein, N-terminal domain (N-Ada 10) | Homeodomain-like | 2 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 2 | 2 | |
PTS-regulatory domain, PRD | PTS-regulatory domain, PRD | 2 | 1 | |
"Winged helix" DNA-binding domain | Chorismate lyase-like | 2 | 1 | |
Aspartate/glutamate racemase | Aspartate/glutamate racemase | 2 | 1 | |
Galactose-binding domain-like | Carbohydrate-binding domain | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | Phosphohistidine domain | 2 | 2 | |
PK beta-barrel domain-like | PK C-terminal domain-like | 2 | 2 | |
Diaminopimelate epimerase-like | Diaminopimelate epimerase-like | 2 | 1 | |
(Trans)glycosidases | Ricin B-like lectins | 2 | 1 | |
Translation proteins | Ribosomal protein S5 domain 2-like | 2 | 1 | |
Nicotinate/Quinolinate PRTase N-terminal domain-like | Nicotinate/Quinolinate PRTase C-terminal domain-like | 2 | 1 | |
Copper amine oxidase, domain N | (Trans)glycosidases | 2 | 2 | |
Six-hairpin glycosidases | Carbohydrate-binding domain | 2 | 2 | |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 2 | 2 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 2 | 1 | |
DNA/RNA polymerases | Lesion bypass DNA polymerase (Y-family), little finger domain | 2 | 1 | |
Single hybrid motif | CoA-dependent acyltransferases | 2 | 2 | |
S-adenosyl-L-methionine-dependent methyltransferases | alpha/beta-Hydrolases | 2 | 2 | |
NHL repeat | TPR-like | 2 | 2 | |
Putative DNA-binding domain | S-adenosyl-L-methionine-dependent methyltransferases | 2 | 1 | |
alpha-helical ferredoxin | Nucleotide-binding domain | 2 | 1 | |
Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 2 | 2 | |
S13-like H2TH domain | Glucocorticoid receptor-like (DNA-binding domain) | 2 | 1 | |
Nucleic acid-binding proteins | Translation proteins SH3-like domain | 2 | 2 | |
Class II aaRS and biotin synthetases | SufE/NifU | 1 | 1 | |
YrdC/RibB | RibA-like | 1 | 1 | |
Homeodomain-like | Glycosyl hydrolase domain | 1 | 1 | |
L domain-like | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
Rhodanese/Cell cycle control phosphatase | Metallo-hydrolase/oxidoreductase | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
CoA-dependent acyltransferases | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Methylesterase CheB, C-terminal domain | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
CBS-domain pair | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Nucleic acid-binding proteins | DNA helicase RuvA subunit, C-terminal domain | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Methylglyoxal synthase-like | 1 | 1 | |
EspE N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | HD-domain/PDEase-like | 1 | 1 | |
Copper amine oxidase, domain N | Triger factor/SurA peptide-binding domain-like | 1 | 1 | |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
FMN-binding split barrel | UbiD C-terminal domain-like | 1 | 1 | |
Thiolase-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Rudiment single hybrid motif | PH0987 N-terminal domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Smc hinge domain | 1 | 1 | |
CBS-domain pair | Homeodomain-like | 1 | 1 | |
Barwin-like endoglucanases | LysM domain | 1 | 1 | |
Class I glutamine amidotransferase-like | LD-carboxypeptidase A C-terminal domain-like | 1 | 1 | |
CheY-binding domain of CheA | CheW-like | 1 | 1 | |
Translation proteins | Translation proteins | 1 | 1 | |
GIY-YIG endonuclease | RuvA domain 2-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | HRDC-like | 1 | 1 | |
Nucleic acid-binding proteins | PHP domain-like | 1 | 1 | |
Zinc beta-ribbon | DNA primase core | 1 | 1 | |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | ACT-like | 1 | 1 | |
YVTN repeat-like/Quinoprotein amine dehydrogenase | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 1 | 1 | |
Zinc beta-ribbon | Prokaryotic SH3-related domain | 1 | 1 | |
Glycoside hydrolase/deacetylase | Fibronectin type III | 1 | 1 | |
Galactose oxidase, central domain | Copper amine oxidase, domain N | 1 | 1 | |
Histidine-containing phosphotransfer domain, HPT domain | CheY-binding domain of CheA | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Pectin lyase-like | CBD9-like | 1 | 1 | |
Arabinanase/levansucrase/invertase | Fibronectin type III | 1 | 1 | |
HisI-like | all-alpha NTP pyrophosphatases | 1 | 1 | |
CheY-like | Methylesterase CheB, C-terminal domain | 1 | 1 | |
Globin-like | Riboflavin synthase domain-like | 1 | 1 | |
UbiD C-terminal domain-like | UbiD C-terminal domain-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Cyclophilin-like | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | DNA mismatch repair protein MutL | 1 | 1 | |
Domain of the SRP/SRP receptor G-proteins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 1 | 1 | |
Thiolase-like | alpha/beta-Hydrolases | 1 | 1 | |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 1 | 1 | |
Alkaline phosphatase-like | Copper amine oxidase, domain N | 1 | 1 | |
Copper amine oxidase, domain N | PKD domain | 1 | 1 | |
Cystatin/monellin | Cystatin/monellin | 1 | 1 | |
PRC-barrel domain | PRC-barrel domain | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Phosphoglucomutase, C-terminal domain | 1 | 1 | |
Arabinanase/levansucrase/invertase | Arabinanase/levansucrase/invertase | 1 | 1 | |
AbfB domain | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | PilZ domain-like | 1 | 1 | |
Glycosyl hydrolase domain | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
PLP-dependent transferases | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
Trigger factor ribosome-binding domain | FKBP-like | 1 | 1 | |
Mechanosensitive channel protein MscS (YggB), transmembrane region | Sm-like ribonucleoproteins | 1 | 1 | |
Pectin lyase-like | SGNH hydrolase | 1 | 1 | |
Nucleotidylyl transferase | tRNA-binding arm | 1 | 1 | |
THUMP domain-like | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | PRTase-like | 1 | 1 | |
Hsp33 domain | HSP33 redox switch-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 1 | 1 | |
Methylesterase CheB, C-terminal domain | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | TPR-like | 1 | 1 | |
DNA repair protein MutS, domain III | SMR domain-like | 1 | 1 | |
LysM domain | Zn-dependent exopeptidases | 1 | 1 | |
Histidine-containing phosphotransfer domain, HPT domain | Nucleotide cyclase | 1 | 1 | |
Copper amine oxidase, domain N | Thermostable phytase (3-phytase) | 1 | 1 | |
Alpha-L RNA-binding motif | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | Thiamin diphosphate-binding fold (THDP-binding) | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Duplicated hybrid motif | 1 | 1 | |
RNase III domain-like | dsRNA-binding domain-like | 1 | 1 | |
LysM domain | (Trans)glycosidases | 1 | 1 | |
Adhesin YadA, collagen-binding domain | Adhesin YadA, collagen-binding domain | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Copper amine oxidase, domain N | Calcium-dependent phosphotriesterase | 1 | 1 | |
2,3-Bisphosphoglycerate-independent phosphoglycerate mutase, substrate-binding domain | Alkaline phosphatase-like | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase activation domain-like | 1 | 1 | |
HD-domain/PDEase-like | TGS-like | 1 | 1 | |
Obg GTP-binding protein N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Nucleic acid-binding proteins | AF1531-like | 1 | 1 | |
PK C-terminal domain-like | Phosphohistidine domain | 1 | 1 | |
HMA, heavy metal-associated domain | HMA, heavy metal-associated domain | 1 | 1 | |
HAMP domain-like | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 | |
Ribonuclease PH domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | DHS-like NAD/FAD-binding domain | 1 | 1 | |
Putative DNA-binding domain | Probable bacterial effector-binding domain | 1 | 1 | |
beta-Galactosidase/glucuronidase domain | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
RCC1/BLIP-II | Copper amine oxidase, domain N | 1 | 1 | |
Transmembrane di-heme cytochromes | Oxidoreductase molybdopterin-binding domain | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Fibronectin type III | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | FMN-dependent nitroreductase-like | 1 | 1 | |
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | TK C-terminal domain-like | 1 | 1 | |
Ribonuclease H-like | AF1531-like | 1 | 1 | |
Rho N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Ribonuclease H-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
ValRS/IleRS/LeuRS editing domain | tRNA-binding arm | 1 | 1 | |
beta-lactamase/transpeptidase-like | Fibronectin type III | 1 | 1 | |
Homeodomain-like | "Helical backbone" metal receptor | 1 | 1 | |
Homodimeric domain of signal transducing histidine kinase | CheW-like | 1 | 1 | |
Pectin lyase-like | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
(Trans)glycosidases | Chitinase insertion domain | 1 | 1 | |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | Nucleic acid-binding proteins | 1 | 1 | |
Riboflavin synthase domain-like | Riboflavin synthase domain-like | 1 | 1 | |
"Winged helix" DNA-binding domain | PTS system IIB component-like | 1 | 1 | |
TGS-like | ACT-like | 1 | 1 | |
CBS-domain pair | PYP-like sensor domain (PAS domain) | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 1 | 1 | |
Integrin alpha N-terminal domain | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
PPK N-terminal domain-like | PHP14-like | 1 | 1 | |
Glutamyl tRNA-reductase catalytic, N-terminal domain | Glutamyl tRNA-reductase dimerization domain | 1 | 1 | |
Class I glutamine amidotransferase-like | Integrin alpha N-terminal domain | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | MesJ substrate recognition domain-like | 1 | 1 | |
CBD9-like | alpha/beta-Hydrolases | 1 | 1 | |
Cryptochrome/photolyase, N-terminal domain | Cryptochrome/photolyase FAD-binding domain | 1 | 1 | |
Homeodomain-like | FAD/NAD(P)-binding domain | 1 | 1 | |
E set domains | Six-hairpin glycosidases | 1 | 1 | |
"Winged helix" DNA-binding domain | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
PDZ domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
PheT/TilS domain | Putative DNA-binding domain | 1 | 1 | |
Nucleoside phosphorylase/phosphoribosyltransferase catalytic domain | Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | 1 | |
Nucleotide cyclase | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |
Tricorn protease N-terminal domain | Carbohydrate-binding domain | 1 | 1 | |
PUA domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Siroheme synthase middle domains-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | CarD-like | 1 | 1 | |
DNA repair protein MutS, domain II | DNA repair protein MutS, domain III | 1 | 1 | |
Methylesterase CheB, C-terminal domain | PYP-like sensor domain (PAS domain) | 1 | 1 | |
Pectin lyase-like | LysM domain | 1 | 1 | |
Lamin A/C globular tail domain | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Alkaline phosphatase-like | E set domains | 1 | 1 | |
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | LysM domain | 1 | 1 | |
Metal cation-transporting ATPase, ATP-binding domain N | HAD-like | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | RuvA domain 2-like | 1 | 1 | |
Sigma3 and sigma4 domains of RNA polymerase sigma factors | NagB/RpiA/CoA transferase-like | 1 | 1 | |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 1 | 1 | |
FliG | FliG | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | Argininosuccinate synthetase, C-terminal domain | 1 | 1 | |
Zn-dependent exopeptidases | Zn-dependent exopeptidases | 1 | 1 | |
Bacillus cereus metalloprotein-like | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 1 | 1 | |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 1 | 1 | |
Copper amine oxidase, domain N | SGNH hydrolase | 1 | 1 | |
Chorismate mutase II | Aldolase | 1 | 1 | |
Nucleotide cyclase | Nucleotide cyclase | 1 | 1 | |
Glycoside hydrolase/deacetylase | Galactose mutarotase-like | 1 | 1 | |
PreATP-grasp domain | Cyclophilin-like | 1 | 1 | |
Tetrapyrrole methylase | Nitrite and sulphite reductase 4Fe-4S domain-like | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | PilZ domain-like | 1 | 1 | |
Epsilon subunit of F1F0-ATP synthase N-terminal domain | Epsilon subunit of F1F0-ATP synthase C-terminal domain | 1 | 1 | |
PreATP-grasp domain | Single hybrid motif | 1 | 1 | |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | PYP-like sensor domain (PAS domain) | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
RCC1/BLIP-II | Carbohydrate-binding domain | 1 | 1 | |
Nucleotide-binding domain | ISP domain | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Carbohydrate-binding domain | 1 | 1 | |
Glycosyl hydrolases family 6, cellulases | Carbohydrate-binding domain | 1 | 1 | |
Dihydropteroate synthetase-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 1 | 1 | |
CalX-like | CalX-like | 1 | 1 | |
Nucleotide cyclase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Copper amine oxidase, domain N | Carboxypeptidase regulatory domain-like | 1 | 1 | |
Tetrapyrrole methylase | all-alpha NTP pyrophosphatases | 1 | 1 | |
Ribosomal protein S5 domain 2-like | DNA mismatch repair protein MutL | 1 | 1 | |
ALDH-like | Dehydroquinate synthase-like | 1 | 1 | |
Metal cation-transporting ATPase, ATP-binding domain N | Calcium ATPase, transmembrane domain M | 1 | 1 | |
Quinoprotein alcohol dehydrogenase-like | Fibronectin type III | 1 | 1 | |
Copper amine oxidase, domain N | FKBP-like | 1 | 1 | |
Trimeric LpxA-like enzymes | Phosphoglucomutase, C-terminal domain | 1 | 1 | |
lambda integrase-like, N-terminal domain | DNA breaking-rejoining enzymes | 1 | 1 | |
PHP domain-like | Ribonuclease H-like | 1 | 1 | |
TROVE domain-like | vWA-like | 1 | 1 | |
Class II aaRS and biotin synthetases | C-terminal domain of ProRS | 1 | 1 | |
Pectin lyase-like | E set domains | 1 | 1 | |
SGNH hydrolase | E set domains | 1 | 1 | |
PTS-regulatory domain, PRD | Phoshotransferase/anion transport protein | 1 | 1 | |
DNase I-like | Mannose-binding lectins | 1 | 1 | |
Homeodomain-like | (Trans)glycosidases | 1 | 1 | |
Pyruvate-ferredoxin oxidoreductase, PFOR, domain III | 4Fe-4S ferredoxins | 1 | 1 | |
Nucleotidylyl transferase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Copper amine oxidase, domain N | Duplicated hybrid motif | 1 | 1 | |
PEP carboxykinase N-terminal domain | PEP carboxykinase-like | 1 | 1 | |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 1 | 1 | |
Aldolase | post-HMGL domain-like | 1 | 1 | |
E set domains | Carbohydrate binding domain | 1 | 1 | |
Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | tRNA-binding arm | 1 | 1 | |
Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 | |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
MoaD/ThiS | Molybdopterin synthase subunit MoaE | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Obg GTP-binding protein C-terminal domain | 1 | 1 | |
L9 N-domain-like | Ribosomal protein L9 C-domain | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
Glutamine synthetase/guanido kinase | GatB/YqeY motif | 1 | 1 | |
Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 1 | 1 | |
Glycoside hydrolase/deacetylase | CBD9-like | 1 | 1 | |
RuvA domain 2-like | RuvA domain 2-like | 1 | 1 | |
SMI1/KNR4-like | ClpS-like | 1 | 1 | |
ABC transporter involved in vitamin B12 uptake, BtuC | ABC transporter involved in vitamin B12 uptake, BtuC | 1 | 1 | |
PKD domain | PKD domain | 1 | 1 | |
Methyl-accepting chemotaxis protein (MCP) signaling domain | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 | |
Glutamyl tRNA-reductase catalytic, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Galactose-binding domain-like | RCC1/BLIP-II | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | PH0987 N-terminal domain-like | 1 | 1 | |
Metallo-dependent phosphatases | LysM domain | 1 | 1 | |
NusB-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Tetrahydrobiopterin biosynthesis enzymes-like | Tetrahydrobiopterin biosynthesis enzymes-like | 1 | 1 | |
vWA-like | vWA-like | 1 | 1 | |
Nucleic acid-binding proteins | ArfGap/RecO-like zinc finger | 1 | 1 | |
Six-hairpin glycosidases | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
RuvA domain 2-like | BRCT domain | 1 | 1 | |
Sm-like ribonucleoproteins | Mechanosensitive channel protein MscS (YggB), C-terminal domain | 1 | 1 | |
Probable ACP-binding domain of malonyl-CoA ACP transacylase | Inosine monophosphate dehydrogenase (IMPDH) | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | RmlC-like cupins | 1 | 1 | |
Copper amine oxidase, domain N | PEBP-like | 1 | 1 | |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 | |
CheY-binding domain of CheA | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Nitrite/Sulfite reductase N-terminal domain-like | Nitrite/Sulfite reductase N-terminal domain-like | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | Radical SAM enzymes | 1 | 1 | |
Class II aaRS ABD-related | C-terminal domain of ProRS | 1 | 1 | |
Nucleotidyltransferase | TGS-like | 1 | 1 | |
Beta-D-glucan exohydrolase, C-terminal domain | Glycosyl hydrolase domain | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | TPR-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Trimeric LpxA-like enzymes | Trimeric LpxA-like enzymes | 1 | 1 | |
Cadherin-like | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Succinyl-CoA synthetase domains | 1 | 1 | |
"Winged helix" DNA-binding domain | C-terminal domain of arginine repressor | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 1 | 1 | |
Regulatory protein AraC | (Trans)glycosidases | 1 | 1 | |
MesJ substrate recognition domain-like | PheT/TilS domain | 1 | 1 | |
E set domains | Carbohydrate-binding domain | 1 | 1 | |
ACT-like | Formyltransferase | 1 | 1 | |
Class II aaRS and biotin synthetases | Translation proteins | 1 | 1 | |
RuvA domain 2-like | JAB1/MPN domain | 1 | 1 | |
Galactose mutarotase-like | Starch-binding domain-like | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TrpR-like | 1 | 1 | |
FabD/lysophospholipase-like | Inosine monophosphate dehydrogenase (IMPDH) | 1 | 1 | |
PreATP-grasp domain | PreATP-grasp domain | 1 | 1 | |
L domain-like | Copper amine oxidase, domain N | 1 | 1 | |
Cadherin-like | Galactose-binding domain-like | 1 | 1 | |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | DinB/YfiT-like putative metalloenzymes | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | GAF domain-like | 1 | 1 | |
Tetrapyrrole methylase | HemD-like | 1 | 1 | |
Copper amine oxidase, domain N | YWTD domain | 1 | 1 | |
Glycoside hydrolase/deacetylase | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 | |
Nucleotide cyclase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
AraD/HMP-PK domain-like | AraD/HMP-PK domain-like | 1 | 1 | |
PPK N-terminal domain-like | Phospholipase D/nuclease | 1 | 1 | |
Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain | Pyrimidine nucleoside phosphorylase C-terminal domain | 1 | 1 | |
Tex N-terminal region-like | Nucleic acid-binding proteins | 1 | 1 | |
Translation proteins | PRC-barrel domain | 1 | 1 | |
Glycerol-3-phosphate (1)-acyltransferase | Acetyl-CoA synthetase-like | 1 | 1 | |
NAD(P)-linked oxidoreductase | alpha-helical ferredoxin | 1 | 1 | |
PrpR receptor domain-like | Homeodomain-like | 1 | 1 | |
DNA repair protein MutS, domain II | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
DinB/YfiT-like putative metalloenzymes | DinB/YfiT-like putative metalloenzymes | 1 | 1 | |
PGBD-like | PGBD-like | 1 | 1 | |
Tex N-terminal region-like | Ribonuclease H-like | 1 | 1 | |
Subtilisin-like | Collagen-binding domain | 1 | 1 | |
PIN domain-like | Ribonuclease H-like | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | Methionine synthase activation domain-like | 1 | 1 | |
TPR-like | TPR-like | 1 | 1 | |
Nucleic acid-binding proteins | Anticodon-binding domain of PheRS | 1 | 1 | |
Protein kinase-like (PK-like) | Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 1 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 1 | 1 | |
PheT/TilS domain | Anticodon-binding domain of PheRS | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | CheW-like | 1 | 1 | |
Tetrapyrrole methylase | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Homocysteine S-methyltransferase | FAD-linked oxidoreductase | 1 | 1 | |
Nucleic acid-binding proteins | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | Nucleic acid-binding proteins | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 1 | 1 | |
Homo-oligomeric flavin-containing Cys decarboxylases, HFCD | CoaB-like | 1 | 1 | |
Lamin A/C globular tail domain | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
PheT/TilS domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Fibronectin type III | Chitinase insertion domain | 1 | 1 | |
Bacillus cereus metalloprotein-like | Fe,Mn superoxide dismutase (SOD), N-terminal domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | ClpP/crotonase | 1 | 1 | |
MetI-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
PreATP-grasp domain | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
HAMP domain-like | EAL domain-like | 1 | 1 | |
Integrin alpha N-terminal domain | SGNH hydrolase | 1 | 1 | |
Carbamate kinase-like | PUA domain-like | 1 | 1 | |
Nucleotidylyl transferase | Ribosomal protein L25-like | 1 | 1 | |
Integrin alpha N-terminal domain | Galactose-binding domain-like | 1 | 1 | |
Trypsin-like serine proteases | TPR-like | 1 | 1 | |
Class I glutamine amidotransferase-like | Class I glutamine amidotransferase-like | 1 | 1 | |
AraD/HMP-PK domain-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 1 | 1 | |
NagB/RpiA/CoA transferase-like | D-ribose-5-phosphate isomerase (RpiA), lid domain | 1 | 1 | |
Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1-deoxy-D-xylulose-5-phosphate reductoisomerase, C-terminal domain | 1 | 1 | |
Regulatory protein AraC | Glycosyl hydrolase domain | 1 | 1 | |
Nucleotidylyl transferase | Alpha-L RNA-binding motif | 1 | 1 | |
MoeA N-terminal region -like | MoeA C-terminal domain-like | 1 | 1 | |
"Winged helix" DNA-binding domain | Phoshotransferase/anion transport protein | 1 | 1 | |
Ribonuclease H-like | DNA/RNA polymerases | 1 | 1 | |
Chondroitin AC/alginate lyase | Cadherin-like | 1 | 1 | |
Families 57/38 glycoside transferase middle domain | UDP-Glycosyltransferase/glycogen phosphorylase | 1 | 1 | |
PreATP-grasp domain | Methylglyoxal synthase-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 1 | 1 | |
5' to 3' exonuclease, C-terminal subdomain | Ribonuclease H-like | 1 | 1 | |
Cyclophilin-like | Cyclophilin-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | SMR domain-like | 1 | 1 | |
PUA domain-like | Nucleotidylyl transferase | 1 | 1 | |
FMN-linked oxidoreductases | 4Fe-4S ferredoxins | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Fibronectin type III | 1 | 1 | |
FAD/NAD(P)-binding domain | HI0933 insert domain-like | 1 | 1 | |
Formyltransferase | FMT C-terminal domain-like | 1 | 1 | |
ISP domain | Bet v1-like | 1 | 1 | |
PurM N-terminal domain-like | PurM N-terminal domain-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | PYP-like sensor domain (PAS domain) | 1 | 1 | |
Nucleotide cyclase | TPR-like | 1 | 1 | |
Lysozyme-like | Fibronectin type III | 1 | 1 | |
HD-domain/PDEase-like | ACT-like | 1 | 1 | |
GAF domain-like | GAF domain-like | 1 | 1 | |
ClpP/crotonase | PGBD-like | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | SCP-like | 1 | 1 | |
Glycoside hydrolase/deacetylase | Copper amine oxidase, domain N | 1 | 1 | |
HD-domain/PDEase-like | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Cadherin-like | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
YjeF N-terminal domain-like | Ribokinase-like | 1 | 1 | |
"Winged helix" DNA-binding domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Folate-binding domain | Aminomethyltransferase beta-barrel domain | 1 | 1 | |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Acetyl-CoA synthetase-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Nitrite and sulphite reductase 4Fe-4S domain-like | Nitrite and sulphite reductase 4Fe-4S domain-like | 1 | 1 | |
YhbC-like, N-terminal domain | YhbC-like, C-terminal domain | 1 | 1 | |
Fe-S cluster assembly (FSCA) domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Penicillin-binding protein 2x (pbp-2x), c-terminal domain | Penicillin-binding protein 2x (pbp-2x), c-terminal domain | 1 | 1 | |
Prokaryotic type I DNA topoisomerase | Zinc beta-ribbon | 1 | 1 | |
DNA-glycosylase | Nudix | 1 | 1 | |
DNA repair protein MutS, domain I | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
alpha/beta-Hydrolases | alpha/beta-Hydrolases | 1 | 1 | |
Nucleic acid-binding proteins | BRCT domain | 1 | 1 | |
Double Clp-N motif | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Homeodomain-like | SIS domain | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Phosphoglucomutase, first 3 domains | 1 | 1 | |
PK beta-barrel domain-like | Phosphohistidine domain | 1 | 1 | |
Zinc beta-ribbon | N-terminal domain of DnaB helicase | 1 | 1 | |
Globin-like | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
Rudiment single hybrid motif | Cyclophilin-like | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 1 | 1 | |
UROD/MetE-like | UROD/MetE-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Phospholipase D/nuclease | 1 | 1 | |
"Winged helix" DNA-binding domain | C-terminal domain of transcriptional repressors | 1 | 1 | |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 1 | 1 | |
"Winged helix" DNA-binding domain | PTS-regulatory domain, PRD | 1 | 1 | |
Histidine-containing phosphotransfer domain, HPT domain | CheW-like | 1 | 1 | |
MoeA N-terminal region -like | Molybdenum cofactor biosynthesis proteins | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 | |
Cytidine deaminase-like | Dihydrofolate reductase-like | 1 | 1 | |
FAD-binding/transporter-associated domain-like | CO dehydrogenase flavoprotein C-terminal domain-like | 1 | 1 | |
PrpR receptor domain-like | PYP-like sensor domain (PAS domain) | 1 | 1 | |
DNA primase core | N-terminal domain of DnaB helicase | 1 | 1 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
SMAD/FHA domain | C-terminal effector domain of the bipartite response regulators | 1 | 1 | |
Chemotaxis receptor methyltransferase CheR, N-terminal domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
beta-lactamase/transpeptidase-like | beta-lactamase/transpeptidase-like | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Guanosine diphospho-D-mannose pyrophosphorylase/mannose-6-phosphate isomerase linker domain | 1 | 1 | |
FAD/NAD(P)-binding domain | Thioredoxin-like | 1 | 1 | |
Voltage-gated potassium channels | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
TrmE connector domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
PIN domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
E set domains | E set domains | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Ricin B-like lectins | 1 | 1 | |
Collagen-binding domain | Collagen-binding domain | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, substrate-binding domain | 1 | 1 | |
PTS-regulatory domain, PRD | PTS system IIB component-like | 1 | 1 | |
Nucleotidylyl transferase | Riboflavin kinase-like | 1 | 1 | |
Ribonuclease PH domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) | Cytochrome c | 1 | 1 | |
Nucleic acid-binding proteins | Putative DNA-binding domain | 1 | 1 | |
Cytochrome P450 | Riboflavin synthase domain-like | 1 | 1 | |
Putative DNA-binding domain | Anticodon-binding domain of PheRS | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TRCF domain-like | 1 | 1 | |
Homocysteine S-methyltransferase | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RecA protein, C-terminal domain | 1 | 1 | |
Globin-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
Periplasmic binding protein-like II | ACT-like | 1 | 1 | |
DNA primase core | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
PUA domain-like | alpha/beta knot | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 1 | 1 | |
"Winged helix" DNA-binding domain | HRDC-like | 1 | 1 | |
PR-1-like | Copper amine oxidase, domain N | 1 | 1 | |
Glycosyl hydrolases family 6, cellulases | Fibronectin type III | 1 | 1 | |
PHP domain-like | RuvA domain 2-like | 1 | 1 | |
Putative DNA-binding domain | Antibiotic binding domain of TipA-like multidrug resistance regulators | 1 | 1 | |
Acid phosphatase/Vanadium-dependent haloperoxidase | Pectin lyase-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
Translation proteins | ThrRS/AlaRS common domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |
Galactose oxidase, central domain | RCC1/BLIP-II | 1 | 1 | |
5' to 3' exonuclease, C-terminal subdomain | DNA/RNA polymerases | 1 | 1 | |
YajQ-like | YajQ-like | 1 | 1 | |
Cytochrome c oxidase subunit II-like, transmembrane region | Cytochrome c | 1 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | RBP11-like subunits of RNA polymerase | 1 | 1 | |
Glycoside hydrolase/deacetylase | (Trans)glycosidases | 1 | 1 | |
Peptide methionine sulfoxide reductase | Mss4-like | 1 | 1 | |
DPP6 N-terminal domain-like | Starch-binding domain-like | 1 | 1 | |
PDZ domain-like | PGBD-like | 1 | 1 | |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 1 | 1 | |
CheY-like | "Winged helix" DNA-binding domain | 1 | 1 | |
Class II aaRS and biotin synthetases | GAD domain-like | 1 | 1 | |
Copper amine oxidase, domain N | Zn-dependent exopeptidases | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | HCP-like | 1 | 1 | |
"Winged helix" DNA-binding domain | PRTase-like | 1 | 1 | |
L9 N-domain-like | Ribonuclease H-like | 1 | 1 | |
Carbohydrate binding domain | Chitinase insertion domain | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | SGNH hydrolase | 1 | 1 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
Nudix | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
4Fe-4S ferredoxins | ARM repeat | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Invasin/intimin cell-adhesion fragments | 1 | 1 | |
Class II aaRS and biotin synthetases | C-terminal domain of transcriptional repressors | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Class II aaRS and biotin synthetases | YbaK/ProRS associated domain | 1 | 1 | |
Nucleic acid-binding proteins | PheT/TilS domain | 1 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | C-terminal domain of RNA polymerase alpha subunit | 1 | 1 | |
Copper amine oxidase, domain N | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase activation domain-like | 1 | 1 | |
Putative DNA-binding domain | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
PreATP-grasp domain | PH0987 N-terminal domain-like | 1 | 1 | |
Class I glutamine amidotransferase-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | Serine metabolism enzymes domain | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | ACT-like | 1 | 1 | |
Calcium ATPase, transduction domain A | Metal cation-transporting ATPase, ATP-binding domain N | 1 | 1 | |
FAD-binding/transporter-associated domain-like | Uridine diphospho-N-Acetylenolpyruvylglucosamine reductase, MurB, C-terminal domain | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain III | 1 | 1 | |
Composite domain of metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
Ribbon-helix-helix | ACT-like | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | PheT/TilS domain | 1 | 1 | |
HD-domain/PDEase-like | Nucleotidyltransferase | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | (Trans)glycosidases | 1 | 1 | |
Ribonuclease H-like | RuvA domain 2-like | 1 | 1 | |
Aminopeptidase/glucanase lid domain | Zn-dependent exopeptidases | 1 | 1 | |
Copper amine oxidase, domain N | Barwin-like endoglucanases | 1 | 1 | |
Carbon-nitrogen hydrolase | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase domain | 1 | 1 | |
2Fe-2S ferredoxin-like | CO dehydrogenase ISP C-domain like | 1 | 1 | |
HAMP domain-like | GAF domain-like | 1 | 1 | |
RuvA domain 2-like | DNA helicase RuvA subunit, C-terminal domain | 1 | 1 | |
C-terminal UvrC-binding domain of UvrB | RuvA domain 2-like | 1 | 1 | |
Methylesterase CheB, C-terminal domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
Methionine synthase domain | Methionine synthase activation domain-like | 1 | 1 | |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Nucleic acid-binding proteins | 1 | 1 | |
Nucleic acid-binding proteins | GAD domain-like | 1 | 1 | |
RCC1/BLIP-II | Type I dockerin domain | 1 | 1 | |
Cupredoxins | Cytochrome c | 1 | 1 | |
EspE N-terminal domain-like | EspE N-terminal domain-like | 1 | 1 | |
PLP-dependent transferases | Class I glutamine amidotransferase-like | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase domain | 1 | 1 | |
Respiratory nitrate reductase 1 gamma chain | alpha-helical ferredoxin | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
UBA-like | Elongation factor Ts (EF-Ts), dimerisation domain | 1 | 1 | |
Globin-like | Methyl-accepting chemotaxis protein (MCP) signaling domain | 1 | 1 | |
Carbamate kinase-like | Zn-dependent exopeptidases | 1 | 1 | |
DPP6 N-terminal domain-like | DPP6 N-terminal domain-like | 1 | 1 | |
beta-N-acetylhexosaminidase-like domain | (Trans)glycosidases | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain II | 1 | 1 | |
Rhodanese/Cell cycle control phosphatase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
"Winged helix" DNA-binding domain | Iron-dependent repressor protein, dimerization domain | 1 | 1 | |
YojJ-like | RuvA domain 2-like | 1 | 1 | |
Nucleotidyltransferase | ACT-like | 1 | 1 | |
PTS system IIB component-like | Phoshotransferase/anion transport protein | 1 | 1 | |
all-alpha NTP pyrophosphatases | all-alpha NTP pyrophosphatases | 1 | 1 | |
Ribonuclease PH domain 2-like | Ribonuclease PH domain 2-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Restriction endonuclease-like | 1 | 1 | |
SGNH hydrolase | SGNH hydrolase | 1 | 1 | |
PIN domain-like | DNA/RNA polymerases | 1 | 1 | |
CBD9-like | CBD9-like | 1 | 1 | |
DeoB insert domain-like | Alkaline phosphatase-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 1 | 1 | |
YVTN repeat-like/Quinoprotein amine dehydrogenase | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Translation proteins | Initiation factor IF2/eIF5b, domain 3 | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | CinA-like | 1 | 1 | |
"Winged helix" DNA-binding domain | LexA/Signal peptidase | 1 | 1 | |
Starch-binding domain-like | Galactose-binding domain-like | 1 | 1 | |
Homocysteine S-methyltransferase | Dihydropteroate synthetase-like | 1 | 1 | |
Cytochrome P450 | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
PUA domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
lambda repressor-like DNA-binding domains | lambda repressor-like DNA-binding domains | 1 | 1 | |
Nucleic acid-binding proteins | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
Rho N-terminal domain-like | Nucleic acid-binding proteins | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | AbrB/MazE/MraZ-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 1 | 1 | |
FMN-dependent nitroreductase-like | alpha/beta-Hydrolases | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | MoeA C-terminal domain-like | 1 | 1 | |
RBP11-like subunits of RNA polymerase | C-terminal domain of RNA polymerase alpha subunit | 1 | 1 | |
PHP domain-like | AF1531-like | 1 | 1 | |
CarD-like | TRCF domain-like | 1 | 1 | |
Cyclophilin-like | Single hybrid motif | 1 | 1 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 1 | 1 | |
YbaK/ProRS associated domain | Class II aaRS ABD-related | 1 | 1 | |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 1 | 1 | |
NagB/RpiA/CoA transferase-like | alpha-helical ferredoxin | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Serine metabolism enzymes domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Glutamyl tRNA-reductase dimerization domain | 1 | 1 | |
Nudix | "Winged helix" DNA-binding domain | 1 | 1 | |
Obg GTP-binding protein N-terminal domain | Obg GTP-binding protein C-terminal domain | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
N-terminal domain of DnaB helicase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Putative DNA-binding domain | Putative DNA-binding domain | 1 | 1 | |
Methionine synthase domain | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
HAMP domain-like | CheY-like | 1 | 1 | |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 1 | 1 | |
Glycoside hydrolase/deacetylase | Starch-binding domain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 1 | 1 | |
Lamin A/C globular tail domain | Cadherin-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Putative methyltransferase TM0872, insert domain | 1 | 1 | |
PurM C-terminal domain-like | PurM C-terminal domain-like | 1 | 1 | |
PH0987 N-terminal domain-like | Single hybrid motif | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | ACT-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal UvrC-binding domain of UvrB | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | ACT-like | 1 | 1 | |
PA domain | Subtilisin-like | 1 | 1 | |
Rudiment single hybrid motif | Single hybrid motif | 1 | 1 | |
ClpP/crotonase | Copper amine oxidase, domain N | 1 | 1 | |
Dihydropteroate synthetase-like | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
PRTase-like | PRTase-like | 1 | 1 | |
PDZ domain-like | Copper amine oxidase, domain N | 1 | 1 | |
Protein kinase-like (PK-like) | GAF domain-like | 1 | 1 | |
Hypothetical protein SAV1430 | ARM repeat | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
Families 57/38 glycoside transferase middle domain | Galactose mutarotase-like | 1 | 1 | |
CheY-like | Nucleotide cyclase | 1 | 1 | |
Periplasmic binding protein-like II | Periplasmic binding protein-like II | 1 | 1 | |
PGBD-like | PR-1-like | 1 | 1 | |
Nucleotidylyl transferase | Nucleic acid-binding proteins | 1 | 1 | |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 1 | 1 | |
Invasin/intimin cell-adhesion fragments | PKD domain | 1 | 1 | |
Transcription factor NusA, N-terminal domain | Nucleic acid-binding proteins | 1 | 1 | |
Cytochrome P450 | Flavoproteins | 1 | 1 | |
Sensory domain-like | HD-domain/PDEase-like | 1 | 1 | |
PrpR receptor domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
MetI-like | MOP-like | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | ClpP/crotonase | 1 | 1 | |
CO dehydrogenase molybdoprotein N-domain-like | Molybdenum cofactor-binding domain | 1 | 1 | |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Methylesterase CheB, C-terminal domain | Chemotaxis receptor methyltransferase CheR, N-terminal domain | 1 | 1 | |
PGBD-like | Cysteine proteinases | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Tex N-terminal region-like | RuvA domain 2-like | 1 | 1 | |
Ribonuclease PH domain 2-like | Nucleic acid-binding proteins | 1 | 1 | |
PHP14-like | Phospholipase D/nuclease | 1 | 1 | |
Trigger factor ribosome-binding domain | Triger factor/SurA peptide-binding domain-like | 1 | 1 | |
YWTD domain | Fibronectin type III | 1 | 1 | |
SirA-like | Rhodanese/Cell cycle control phosphatase | 1 | 1 | |
"Winged helix" DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 | |
Mechanosensitive channel protein MscS (YggB), transmembrane region | Mechanosensitive channel protein MscS (YggB), C-terminal domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Methylglyoxal synthase-like | 1 | 1 | |
CbiG N-terminal domain-like | CobE/GbiG C-terminal domain-like | 1 | 1 | |
Trimeric LpxA-like enzymes | Phosphoglucomutase, first 3 domains | 1 | 1 | |
Tricorn protease N-terminal domain | Tricorn protease N-terminal domain | 1 | 1 | |
Terpenoid cyclases/Protein prenyltransferases | Terpenoid cyclases/Protein prenyltransferases | 1 | 1 | |
CheY-binding domain of CheA | Homodimeric domain of signal transducing histidine kinase | 1 | 1 | |