All pairs of domain combinations at the superfamily level are listed here.
The identification of domain pairs does not account for the possibility of non-contiguous domains. Inserted, or interlaced, domains are seen as having a simple pair ordering.
The links below permit the addition or removal of specific sets of domain combination pairs.
Change the list of genome two-letter codes in the 'Include genomes' box to include domain-pairs from those genomes.
Change the list of genomes in the 'Exclude genomes' box to exclude domain-pairs from those genomes.
List of all two-letter genome codes.
Superfamily (N) | Superfamily (C) | Number of occurrances | Number unique | |
beta-beta-alpha zinc fingers | beta-beta-alpha zinc fingers | 413 | 150 | |
KRAB domain (Kruppel-associated box) | beta-beta-alpha zinc fingers | 169 | 62 | |
Immunoglobulin | Immunoglobulin | 161 | 84 | |
P-loop containing nucleoside triphosphate hydrolases | P-loop containing nucleoside triphosphate hydrolases | 141 | 66 | |
Fibronectin type III | Fibronectin type III | 80 | 64 | |
Cadherin-like | Cadherin-like | 72 | 28 | |
EGF/Laminin | EGF/Laminin | 64 | 60 | |
RNA-binding domain, RBD | RNA-binding domain, RBD | 57 | 27 | |
TPR-like | TPR-like | 52 | 20 | |
Immunoglobulin | Fibronectin type III | 51 | 45 | |
Protein kinase-like (PK-like) | Protein kinase-like (PK-like) | 51 | 24 | |
ARM repeat | ARM repeat | 47 | 25 | |
DBL homology domain (DH-domain) | PH domain-like | 39 | 30 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | C2 domain (Calcium/lipid-binding domain, CaLB) | 37 | 21 | |
Actin-like ATPase domain | Actin-like ATPase domain | 35 | 14 | |
Nicotinic receptor ligand binding domain-like | Neurotransmitter-gated ion-channel transmembrane pore | 33 | 6 | |
PH domain-like | PH domain-like | 32 | 26 | |
POZ domain | Kelch motif | 32 | 5 | |
Second domain of FERM | PH domain-like | 32 | 23 | |
Glucocorticoid receptor-like (DNA-binding domain) | Glucocorticoid receptor-like (DNA-binding domain) | 32 | 20 | |
Retrovirus capsid dimerization domain-like | beta-beta-alpha zinc fingers | 31 | 21 | |
TSP-1 type 1 repeat | TSP-1 type 1 repeat | 30 | 30 | |
PDZ domain-like | PDZ domain-like | 30 | 27 | |
Glucocorticoid receptor-like (DNA-binding domain) | Nuclear receptor ligand-binding domain | 28 | 8 | |
Homeodomain-like | Homeodomain-like | 28 | 13 | |
Growth factor receptor domain | EGF/Laminin | 26 | 26 | |
Complement control module/SCR domain | Complement control module/SCR domain | 26 | 26 | |
Concanavalin A-like lectins/glucanases | Concanavalin A-like lectins/glucanases | 26 | 23 | |
EF-hand | EF-hand | 24 | 16 | |
L domain-like | L domain-like | 24 | 21 | |
PH domain-like | SH3-domain | 23 | 20 | |
Concanavalin A-like lectins/glucanases | EGF/Laminin | 23 | 22 | |
Ubiquitin-like | PH domain-like | 23 | 13 | |
Tudor/PWWP/MBT | Tudor/PWWP/MBT | 23 | 18 | |
Intermediate filament protein, coiled coil region | Intermediate filament protein, coiled coil region | 23 | 7 | |
HAD-like | Calcium ATPase, transmembrane domain M | 22 | 10 | |
POZ domain | beta-beta-alpha zinc fingers | 22 | 12 | |
Metal cation-transporting ATPase, ATP-binding domain N | Calcium ATPase, transmembrane domain M | 22 | 10 | |
Calcium ATPase, transduction domain A | Metal cation-transporting ATPase, ATP-binding domain N | 21 | 9 | |
Calcium ATPase, transduction domain A | Calcium ATPase, transmembrane domain M | 21 | 9 | |
Calcium ATPase, transduction domain A | HAD-like | 21 | 9 | |
Spermadhesin, CUB domain | Spermadhesin, CUB domain | 20 | 19 | |
Metal cation-transporting ATPase, ATP-binding domain N | HAD-like | 20 | 8 | |
SH2 domain | SH3-domain | 20 | 16 | |
Growth factor receptor domain | Growth factor receptor domain | 20 | 20 | |
ARM repeat | Protein kinase-like (PK-like) | 20 | 18 | |
ABC transporter transmembrane region | P-loop containing nucleoside triphosphate hydrolases | 20 | 10 | |
Fibronectin type III | Protein kinase-like (PK-like) | 20 | 15 | |
RING/U-box | Concanavalin A-like lectins/glucanases | 19 | 7 | |
RING/U-box | B-box zinc-binding domain | 19 | 5 | |
MHC antigen-recognition domain | Immunoglobulin | 19 | 2 | |
L domain-like | Immunoglobulin | 19 | 12 | |
Thioredoxin-like | GST C-terminal domain-like | 19 | 3 | |
Immunoglobulin | Protein kinase-like (PK-like) | 19 | 17 | |
Ubiquitin-like | Second domain of FERM | 18 | 10 | |
LDL receptor-like module | LDL receptor-like module | 18 | 18 | |
Voltage-gated potassium channels | Voltage-gated potassium channels | 18 | 7 | |
Cyclin-like | Cyclin-like | 18 | 7 | |
Ypt/Rab-GAP domain of gyp1p | Ypt/Rab-GAP domain of gyp1p | 18 | 9 | |
PH domain-like | Protein kinase-like (PK-like) | 18 | 16 | |
Ankyrin repeat | Ankyrin repeat | 18 | 16 | |
Spectrin repeat | Spectrin repeat | 17 | 17 | |
PH domain-like | SH2 domain | 17 | 15 | |
PH domain-like | GTPase activation domain, GAP | 17 | 14 | |
(Phosphotyrosine protein) phosphatases II | (Phosphotyrosine protein) phosphatases II | 17 | 15 | |
PH domain-like | (Phosphotyrosine protein) phosphatases II | 17 | 12 | |
Metalloproteases ("zincins"), catalytic domain | Hemopexin-like domain | 17 | 7 | |
PDZ domain-like | P-loop containing nucleoside triphosphate hydrolases | 17 | 14 | |
MFS general substrate transporter | MFS general substrate transporter | 17 | 6 | |
SH3-domain | SH3-domain | 16 | 15 | |
RING/U-box | RING/U-box | 16 | 13 | |
PDZ domain-like | PH domain-like | 16 | 15 | |
Retrovirus capsid dimerization domain-like | KRAB domain (Kruppel-associated box) | 15 | 11 | |
Cysteine proteinases | Cysteine proteinases | 15 | 10 | |
GroES-like | NAD(P)-binding Rossmann-fold domains | 15 | 6 | |
P-loop containing nucleoside triphosphate hydrolases | SH3-domain | 15 | 11 | |
SH2 domain | Protein kinase-like (PK-like) | 15 | 11 | |
B-box zinc-binding domain | Concanavalin A-like lectins/glucanases | 15 | 5 | |
WW domain | WW domain | 15 | 15 | |
WD40 repeat-like | WD40 repeat-like | 15 | 11 | |
Thioredoxin-like | Thioredoxin-like | 15 | 9 | |
Integrin alpha N-terminal domain | Integrin domains | 14 | 10 | |
BAR/IMD domain-like | SH3-domain | 14 | 9 | |
Tudor/PWWP/MBT | FYVE/PHD zinc finger | 14 | 7 | |
PGBD-like | Metalloproteases ("zincins"), catalytic domain | 14 | 6 | |
Family A G protein-coupled receptor-like | Family A G protein-coupled receptor-like | 14 | 3 | |
FAD/NAD(P)-binding domain | FAD-linked reductases, C-terminal domain | 14 | 9 | |
HLH, helix-loop-helix DNA-binding domain | PYP-like sensor domain (PAS domain) | 14 | 7 | |
vWA-like | vWA-like | 14 | 14 | |
Metalloproteases ("zincins"), catalytic domain | TSP-1 type 1 repeat | 14 | 14 | |
SH3-domain | Protein kinase-like (PK-like) | 14 | 10 | |
FYVE/PHD zinc finger | FYVE/PHD zinc finger | 13 | 10 | |
Integrin domains | Integrin domains | 13 | 9 | |
P-loop containing nucleoside triphosphate hydrolases | Myosin rod fragments | 13 | 10 | |
GroEL equatorial domain-like | GroEL apical domain-like | 13 | 5 | |
PGBD-like | Hemopexin-like domain | 13 | 5 | |
FAD/NAD(P)-binding domain | FAD/NAD(P)-binding domain | 13 | 6 | |
Cysteine-rich domain | Protein kinase-like (PK-like) | 13 | 11 | |
POZ domain | Voltage-gated potassium channels | 13 | 3 | |
Myosin rod fragments | Myosin rod fragments | 13 | 10 | |
vWA-like | Integrin domains | 13 | 11 | |
Nucleotidyltransferase | PAP/OAS1 substrate-binding domain | 13 | 9 | |
Tubulin nucleotide-binding domain-like | Tubulin C-terminal domain-like | 13 | 2 | |
Fibronectin type III | Concanavalin A-like lectins/glucanases | 13 | 9 | |
Periplasmic binding protein-like I | Periplasmic binding protein-like II | 13 | 7 | |
ABC transporter transmembrane region | ABC transporter transmembrane region | 13 | 7 | |
C-type lectin-like | C-type lectin-like | 13 | 8 | |
Eukaryotic type KH-domain (KH-domain type I) | Eukaryotic type KH-domain (KH-domain type I) | 13 | 12 | |
Transducin (alpha subunit), insertion domain | P-loop containing nucleoside triphosphate hydrolases | 12 | 3 | |
Ankyrin repeat | SOCS box-like | 12 | 6 | |
Metalloproteases ("zincins"), catalytic domain | Blood coagulation inhibitor (disintegrin) | 12 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Translation proteins | 12 | 10 | |
E set domains | E set domains | 12 | 9 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Protein kinase-like (PK-like) | 12 | 9 | |
P-loop containing nucleoside triphosphate hydrolases | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 12 | 2 | |
PH domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 12 | 11 | |
L domain-like | Fibronectin type III | 11 | 8 | |
Galactose-binding domain-like | Protein kinase-like (PK-like) | 11 | 6 | |
Snake toxin-like | Protein kinase-like (PK-like) | 11 | 3 | |
Protein kinase-like (PK-like) | SAM/Pointed domain | 11 | 6 | |
FYVE/PHD zinc finger | Bromodomain | 11 | 7 | |
Trypsin-like serine proteases | Trypsin-like serine proteases | 11 | 7 | |
S-adenosyl-L-methionine-dependent methyltransferases | S-adenosyl-L-methionine-dependent methyltransferases | 11 | 5 | |
Fibronectin type III | (Phosphotyrosine protein) phosphatases II | 11 | 10 | |
Voltage-gated potassium channels | cAMP-binding domain-like | 11 | 6 | |
BAR/IMD domain-like | GTPase activation domain, GAP | 10 | 8 | |
Nucleic acid-binding proteins | Nucleic acid-binding proteins | 10 | 7 | |
vWA-like | EGF/Laminin | 10 | 10 | |
(Trans)glycosidases | (Trans)glycosidases | 10 | 8 | |
Ubiquitin-like | Protein kinase-like (PK-like) | 10 | 7 | |
SH3-domain | DBL homology domain (DH-domain) | 10 | 10 | |
lambda repressor-like DNA-binding domains | Homeodomain-like | 10 | 8 | |
Nucleotidylyl transferase | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 10 | 7 | |
PDZ domain-like | SH3-domain | 10 | 7 | |
Leukotriene A4 hydrolase N-terminal domain | Metalloproteases ("zincins"), catalytic domain | 10 | 4 | |
SRCR-like | SRCR-like | 10 | 9 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Ribosomal protein S5 domain 2-like | 10 | 10 | |
Cysteine proteinases | Calpain large subunit, middle domain (domain III) | 10 | 7 | |
"Winged helix" DNA-binding domain | "Winged helix" DNA-binding domain | 10 | 8 | |
RING/U-box | Cysteine proteinases | 10 | 8 | |
P-loop containing nucleoside triphosphate hydrolases | DEATH domain | 10 | 7 | |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 10 | 7 | |
Calponin-homology domain, CH-domain | Spectrin repeat | 10 | 10 | |
Cysteine-rich domain | Cysteine-rich domain | 10 | 7 | |
RNI-like | DEATH domain | 10 | 6 | |
Nucleotide-diphospho-sugar transferases | Ricin B-like lectins | 10 | 4 | |
alpha/beta-Hydrolases | alpha/beta-Hydrolases | 9 | 3 | |
Nucleic acid-binding proteins | P-loop containing nucleoside triphosphate hydrolases | 9 | 5 | |
ARM repeat | WD40 repeat-like | 9 | 9 | |
SNF-like | SNF-like | 9 | 3 | |
Galactose-binding domain-like | Fibronectin type III | 9 | 5 | |
PreATP-grasp domain | Glutathione synthetase ATP-binding domain-like | 9 | 7 | |
cAMP-binding domain-like | cAMP-binding domain-like | 9 | 7 | |
Cytochrome P450 | Cytochrome P450 | 9 | 2 | |
L domain-like | Protein kinase-like (PK-like) | 9 | 8 | |
dsRNA-binding domain-like | dsRNA-binding domain-like | 9 | 7 | |
Kelch motif | Kelch motif | 9 | 5 | |
Complement control module/SCR domain | Spermadhesin, CUB domain | 9 | 9 | |
PYP-like sensor domain (PAS domain) | PYP-like sensor domain (PAS domain) | 9 | 5 | |
Growth factor receptor domain | Protein kinase-like (PK-like) | 9 | 7 | |
Sema domain | Plexin repeat | 9 | 7 | |
L27 domain | PDZ domain-like | 9 | 6 | |
PH domain-like | Cysteine-rich domain | 9 | 8 | |
YWTD domain | LDL receptor-like module | 9 | 9 | |
GroEL-intermediate domain like | GroEL apical domain-like | 9 | 3 | |
WW domain | Hect, E3 ligase catalytic domain | 9 | 9 | |
EF-hand | C2 domain (Calcium/lipid-binding domain, CaLB) | 9 | 8 | |
PLP-dependent transferases | PLP-dependent transferases | 8 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | RNI-like | 8 | 5 | |
SAM/Pointed domain | "Winged helix" DNA-binding domain | 8 | 4 | |
Riboflavin synthase domain-like | Ferredoxin reductase-like, C-terminal NADP-linked domain | 8 | 6 | |
Immunoglobulin | Toll/Interleukin receptor TIR domain | 8 | 6 | |
EGF/Laminin | YWTD domain | 8 | 8 | |
YWTD domain | YWTD domain | 8 | 8 | |
PH domain-like | EF-hand | 8 | 7 | |
NAD(P)-binding Rossmann-fold domains | LDH C-terminal domain-like | 8 | 4 | |
Galactose-binding domain-like | Galactose-binding domain-like | 8 | 7 | |
Calponin-homology domain, CH-domain | EF-hand | 8 | 7 | |
Class II aaRS and biotin synthetases | Class II aaRS ABD-related | 8 | 8 | |
CRAL/TRIO N-terminal domain | CRAL/TRIO domain | 8 | 5 | |
(Trans)glycosidases | Glycosyl hydrolase domain | 8 | 5 | |
NAD(P)-binding Rossmann-fold domains | 6-phosphogluconate dehydrogenase C-terminal domain-like | 8 | 7 | |
Fibronectin type III | SAM/Pointed domain | 8 | 4 | |
Ubiquitin-like | Ras GEF | 8 | 7 | |
Immunoglobulin | Concanavalin A-like lectins/glucanases | 8 | 7 | |
BEACH domain | WD40 repeat-like | 8 | 7 | |
Voltage-gated potassium channels | E set domains | 8 | 2 | |
Ribonuclease H-like | Ribonuclease H-like | 8 | 6 | |
p53-like transcription factors | E set domains | 8 | 4 | |
Growth factor receptor domain | Concanavalin A-like lectins/glucanases | 8 | 8 | |
Metalloproteases ("zincins"), catalytic domain | Metalloproteases ("zincins"), catalytic domain | 8 | 5 | |
Chromo domain-like | Chromo domain-like | 8 | 3 | |
GroEL equatorial domain-like | GroEL-intermediate domain like | 8 | 2 | |
BAR/IMD domain-like | PH domain-like | 8 | 5 | |
ARM repeat | PH domain-like | 8 | 7 | |
Ankyrin repeat | SAM/Pointed domain | 8 | 6 | |
Mitochondrial carrier | Mitochondrial carrier | 8 | 1 | |
PLC-like phosphodiesterases | C2 domain (Calcium/lipid-binding domain, CaLB) | 8 | 7 | |
PH domain-like | Oxysterol-binding protein-like | 8 | 5 | |
EGF/Laminin | Spermadhesin, CUB domain | 8 | 8 | |
Cysteine proteinases | Transglutaminase, two C-terminal domains | 8 | 4 | |
EF-hand | PLC-like phosphodiesterases | 8 | 7 | |
BRCT domain | BRCT domain | 7 | 7 | |
ARM repeat | Formin homology 2 domain (FH2 domain) | 7 | 6 | |
PH domain-like | ArfGap/RecO-like zinc finger | 7 | 6 | |
Ubiquitin-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 7 | 5 | |
Kringle-like | Trypsin-like serine proteases | 7 | 7 | |
PH domain-like | Ankyrin repeat | 7 | 6 | |
Thiolase-like | Thiolase-like | 7 | 3 | |
Serpins | Serpins | 7 | 2 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | ARM repeat | 7 | 5 | |
Galactose-binding domain-like | Concanavalin A-like lectins/glucanases | 7 | 6 | |
Ankyrin repeat | P-loop containing nucleoside triphosphate hydrolases | 7 | 6 | |
Cystatin/monellin | Cystatin/monellin | 7 | 2 | |
PH domain-like | WD40 repeat-like | 7 | 6 | |
Kringle-like | Kringle-like | 7 | 7 | |
vWA-like | Integrin alpha N-terminal domain | 7 | 5 | |
Nucleotide cyclase | Nucleotide cyclase | 7 | 6 | |
ENTH/VHS domain | GAT-like domain | 7 | 2 | |
C-type lectin-like | EGF/Laminin | 7 | 7 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Cysteine-rich domain | 7 | 6 | |
Cysteine proteinases | EF-hand | 7 | 5 | |
PH domain-like | PLC-like phosphodiesterases | 7 | 6 | |
SAM/Pointed domain | SAM/Pointed domain | 7 | 5 | |
Cysteine-rich domain | NAD kinase/diacylglycerol kinase-like | 7 | 6 | |
PAZ domain | Ribonuclease H-like | 7 | 4 | |
RCC1/BLIP-II | Hect, E3 ligase catalytic domain | 7 | 6 | |
POZ domain | POZ domain | 7 | 6 | |
FYVE/PHD zinc finger | SET domain | 7 | 5 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), peptide-binding domain | 7 | 6 | |
SMAD/FHA domain | P-loop containing nucleoside triphosphate hydrolases | 7 | 6 | |
beta-beta-alpha zinc fingers | Homeodomain-like | 7 | 7 | |
Chromo domain-like | P-loop containing nucleoside triphosphate hydrolases | 7 | 5 | |
Transglutaminase, two C-terminal domains | Transglutaminase, two C-terminal domains | 7 | 3 | |
Zn-dependent exopeptidases | Zn-dependent exopeptidases | 7 | 6 | |
Spermadhesin, CUB domain | LDL receptor-like module | 7 | 6 | |
PH domain-like | BEACH domain | 7 | 6 | |
Spectrin repeat | EF-hand | 7 | 7 | |
FnI-like domain | FnI-like domain | 7 | 7 | |
Galactose-binding domain-like | SAM/Pointed domain | 7 | 3 | |
Aminoacid dehydrogenase-like, N-terminal domain | NAD(P)-binding Rossmann-fold domains | 7 | 5 | |
"Winged helix" DNA-binding domain | E2F-DP heterodimerization region | 7 | 4 | |
Ankyrin repeat | DEATH domain | 7 | 5 | |
alpha-catenin/vinculin-like | alpha-catenin/vinculin-like | 7 | 6 | |
Ubiquitin-like | ARM repeat | 7 | 5 | |
beta-sandwich domain of Sec23/24 | vWA-like | 6 | 5 | |
EGF/Laminin | Complement control module/SCR domain | 6 | 6 | |
Acetyl-CoA synthetase-like | Acetyl-CoA synthetase-like | 6 | 4 | |
L27 domain | P-loop containing nucleoside triphosphate hydrolases | 6 | 4 | |
Doublecortin (DC) | Doublecortin (DC) | 6 | 5 | |
Galactose-binding domain-like | Growth factor receptor domain | 6 | 4 | |
F-box domain | RNI-like | 6 | 4 | |
Actin-like ATPase domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 6 | 5 | |
Alkaline phosphatase-like | Alkaline phosphatase-like | 6 | 3 | |
LDL receptor-like module | EGF/Laminin | 6 | 6 | |
Nucleotidylyl transferase | ValRS/IleRS/LeuRS editing domain | 6 | 4 | |
Growth factor receptor domain | Fibronectin type III | 6 | 4 | |
Metallo-dependent hydrolases | Metallo-dependent hydrolases | 6 | 3 | |
Spectrin repeat | PH domain-like | 6 | 6 | |
Formate/glycerate dehydrogenase catalytic domain-like | NAD(P)-binding Rossmann-fold domains | 6 | 4 | |
RCC1/BLIP-II | RCC1/BLIP-II | 6 | 6 | |
WD40 repeat-like | Quinoprotein alcohol dehydrogenase-like | 6 | 6 | |
Fibronectin type III | EGF/Laminin | 6 | 5 | |
Clavaminate synthase-like | FYVE/PHD zinc finger | 6 | 6 | |
beta-sandwich domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 6 | 5 | |
UBA-like | Ubiquitin-like | 6 | 6 | |
ValRS/IleRS/LeuRS editing domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 6 | 4 | |
E set domains | Cysteine proteinases | 6 | 3 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | WW domain | 6 | 6 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Hect, E3 ligase catalytic domain | 6 | 6 | |
L domain-like | Toll/Interleukin receptor TIR domain | 6 | 5 | |
E set domains | Transglutaminase, two C-terminal domains | 6 | 3 | |
Ankyrin repeat | Protein kinase-like (PK-like) | 6 | 5 | |
L domain-like | Family A G protein-coupled receptor-like | 6 | 6 | |
alpha/beta-Hydrolases | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 6 | 1 | |
PX domain | Protein kinase-like (PK-like) | 6 | 5 | |
Calcium ATPase, transmembrane domain M | Calcium ATPase, transmembrane domain M | 6 | 4 | |
BRK domain-like | P-loop containing nucleoside triphosphate hydrolases | 6 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | PH domain-like | 6 | 6 | |
DUSP-like | Cysteine proteinases | 6 | 6 | |
DEATH domain | Caspase-like | 6 | 3 | |
Protease propeptides/inhibitors | Zn-dependent exopeptidases | 6 | 2 | |
PH domain-like | FYVE/PHD zinc finger | 6 | 5 | |
vWA-like | C-terminal, gelsolin-like domain of Sec23/24 | 6 | 5 | |
Actin depolymerizing proteins | Actin depolymerizing proteins | 6 | 5 | |
Protein kinase-like (PK-like) | DEATH domain | 6 | 3 | |
GAF domain-like | HD-domain/PDEase-like | 6 | 4 | |
GTPase activation domain, GAP | SH3-domain | 6 | 5 | |
Calpain large subunit, middle domain (domain III) | EF-hand | 6 | 4 | |
Bromodomain | Bromodomain | 6 | 6 | |
Spermadhesin, CUB domain | Trypsin-like serine proteases | 6 | 6 | |
SEA domain | Trypsin-like serine proteases | 6 | 2 | |
NAD(P)-binding Rossmann-fold domains | NAD(P)-binding Rossmann-fold domains | 6 | 4 | |
TSP-1 type 1 repeat | Immunoglobulin | 6 | 6 | |
P-loop containing nucleoside triphosphate hydrolases | Protein kinase-like (PK-like) | 6 | 4 | |
CalX-like | CalX-like | 6 | 6 | |
Class II aaRS and biotin synthetases | ThrRS/AlaRS common domain | 5 | 5 | |
Ubiquitin-like | Ubiquitin-like | 5 | 5 | |
Sema domain | Immunoglobulin | 5 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | Ribosomal protein S5 domain 2-like | 5 | 5 | |
gamma-Crystallin-like | gamma-Crystallin-like | 5 | 5 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, first 3 domains | 5 | 4 | |
Cullin repeat-like | "Winged helix" DNA-binding domain | 5 | 4 | |
Glutathione synthetase ATP-binding domain-like | Rudiment single hybrid motif | 5 | 3 | |
Protein kinase-like (PK-like) | KA1-like | 5 | 3 | |
Kazal-type serine protease inhibitors | Kazal-type serine protease inhibitors | 5 | 5 | |
Helical domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 5 | 4 | |
Subtilisin-like | Galactose-binding domain-like | 5 | 4 | |
Heat shock protein 70kD (HSP70), peptide-binding domain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 5 | 4 | |
DNA repair protein MutS, domain III | P-loop containing nucleoside triphosphate hydrolases | 5 | 4 | |
HMG-box | HMG-box | 5 | 3 | |
PH domain-like | Ras GEF | 5 | 4 | |
Zn-finger domain of Sec23/24 | C-terminal, gelsolin-like domain of Sec23/24 | 5 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | EF-G C-terminal domain-like | 5 | 5 | |
Clc chloride channel | CBS-domain pair | 5 | 4 | |
Kazal-type serine protease inhibitors | EF-hand | 5 | 5 | |
Elafin-like | Elafin-like | 5 | 5 | |
Nucleic acid-binding proteins | Class II aaRS and biotin synthetases | 5 | 4 | |
Cupredoxins | Cupredoxins | 5 | 5 | |
STAT | SH2 domain | 5 | 1 | |
vWA-like | Helical domain of Sec23/24 | 5 | 4 | |
Transcription factor STAT-4 N-domain | p53-like transcription factors | 5 | 1 | |
CoA-dependent acyltransferases | CoA-dependent acyltransferases | 5 | 4 | |
WW domain | PH domain-like | 5 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | Sec63 N-terminal domain-like | 5 | 4 | |
LuxS/MPP-like metallohydrolase | LuxS/MPP-like metallohydrolase | 5 | 4 | |
Hect, E3 ligase catalytic domain | Hect, E3 ligase catalytic domain | 5 | 5 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | GTPase activation domain, GAP | 5 | 5 | |
Thiamin diphosphate-binding fold (THDP-binding) | Thiamin diphosphate-binding fold (THDP-binding) | 5 | 5 | |
Galactose-binding domain-like | EGF/Laminin | 5 | 4 | |
LDL receptor-like module | Trypsin-like serine proteases | 5 | 5 | |
HSP40/DnaJ peptide-binding domain | HSP40/DnaJ peptide-binding domain | 5 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | "Winged helix" DNA-binding domain | 5 | 4 | |
MIR domain | MIR domain | 5 | 5 | |
Ran binding protein zinc finger-like | Ran binding protein zinc finger-like | 5 | 4 | |
Oxysterol-binding protein-like | Oxysterol-binding protein-like | 5 | 5 | |
PreATP-grasp domain | Rudiment single hybrid motif | 5 | 3 | |
EF-hand | RING/U-box | 5 | 5 | |
F-box domain | WD40 repeat-like | 5 | 2 | |
ArfGap/RecO-like zinc finger | Ankyrin repeat | 5 | 4 | |
beta-sandwich domain of Sec23/24 | Zn-finger domain of Sec23/24 | 5 | 4 | |
Translation proteins | EF-G C-terminal domain-like | 5 | 5 | |
Plexin repeat | vWA-like | 5 | 5 | |
MFS general substrate transporter | Kazal-type serine protease inhibitors | 5 | 3 | |
(Phosphotyrosine protein) phosphatases II | C2 domain (Calcium/lipid-binding domain, CaLB) | 5 | 5 | |
Chaperone J-domain | HSP40/DnaJ peptide-binding domain | 5 | 5 | |
Nucleotidyltransferase | Nucleotidyltransferase | 5 | 5 | |
DPP6 N-terminal domain-like | alpha/beta-Hydrolases | 5 | 2 | |
Transcription factor STAT-4 N-domain | SH2 domain | 5 | 1 | |
PYP-like sensor domain (PAS domain) | cAMP-binding domain-like | 5 | 3 | |
Bromodomain | Tudor/PWWP/MBT | 5 | 2 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | FabD/lysophospholipase-like | 5 | 3 | |
Thiamin diphosphate-binding fold (THDP-binding) | TK C-terminal domain-like | 5 | 4 | |
SH2 domain | SH2 domain | 5 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | Smc hinge domain | 5 | 4 | |
SH2 domain | SOCS box-like | 5 | 2 | |
Nucleotide-diphospho-sugar transferases | Nucleotide-diphospho-sugar transferases | 5 | 5 | |
SMAD MH1 domain | SMAD/FHA domain | 5 | 2 | |
Protein kinase-like (PK-like) | PDZ domain-like | 5 | 5 | |
ARM repeat | Clathrin adaptor appendage domain | 5 | 4 | |
EF-hand | Cysteine-rich domain | 5 | 4 | |
Zn-finger domain of Sec23/24 | vWA-like | 5 | 4 | |
Bactericidal permeability-increasing protein, BPI | Bactericidal permeability-increasing protein, BPI | 5 | 1 | |
beta-sandwich domain of Sec23/24 | Helical domain of Sec23/24 | 5 | 4 | |
Galactose mutarotase-like | Glycosyl hydrolase domain | 5 | 4 | |
Metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 5 | 3 | |
Transcription factor STAT-4 N-domain | STAT | 5 | 1 | |
Growth factor receptor domain | YWTD domain | 5 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | WD40 repeat-like | 5 | 4 | |
STAT | p53-like transcription factors | 5 | 1 | |
Second domain of FERM | (Phosphotyrosine protein) phosphatases II | 5 | 5 | |
Galactose mutarotase-like | (Trans)glycosidases | 5 | 4 | |
CCCH zinc finger | CCCH zinc finger | 5 | 3 | |
L domain-like | Growth factor receptor domain | 5 | 5 | |
RING/U-box | CCCH zinc finger | 5 | 4 | |
Terpenoid cyclases/Protein prenyltransferases | Alpha-macroglobulin receptor domain | 5 | 5 | |
HCP-like | HCP-like | 5 | 5 | |
Cadherin-like | Concanavalin A-like lectins/glucanases | 5 | 4 | |
Growth factor receptor domain | FnI-like domain | 5 | 5 | |
P-loop containing nucleoside triphosphate hydrolases | post-AAA+ oligomerization domain-like | 5 | 2 | |
vWA-like | Growth factor receptor domain | 5 | 5 | |
p53-like transcription factors | SH2 domain | 5 | 1 | |
GAF domain-like | GAF domain-like | 5 | 3 | |
Periplasmic binding protein-like I | Protein kinase-like (PK-like) | 5 | 5 | |
Tudor/PWWP/MBT | SAM/Pointed domain | 5 | 3 | |
Glucocorticoid receptor-like (DNA-binding domain) | Homeodomain-like | 5 | 5 | |
Thioesterase/thiol ester dehydrase-isomerase | Thioesterase/thiol ester dehydrase-isomerase | 4 | 4 | |
EGF/Laminin | Trypsin-like serine proteases | 4 | 3 | |
Concanavalin A-like lectins/glucanases | P-loop containing nucleoside triphosphate hydrolases | 4 | 4 | |
Glucocorticoid receptor-like (DNA-binding domain) | PDZ domain-like | 4 | 4 | |
Rudiment single hybrid motif | Single hybrid motif | 4 | 2 | |
Protein kinase-like (PK-like) | Nucleotide cyclase | 4 | 4 | |
Nuclear receptor ligand-binding domain | Nuclear receptor ligand-binding domain | 4 | 3 | |
SH3-domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 4 | |
Galactose mutarotase-like | Galactose mutarotase-like | 4 | 4 | |
Concanavalin A-like lectins/glucanases | TSP type-3 repeat | 4 | 4 | |
Calponin-homology domain, CH-domain | GAS2 domain-like | 4 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | Tropomyosin | 4 | 4 | |
EF-G C-terminal domain-like | Ribosomal protein S5 domain 2-like | 4 | 4 | |
Glutathione synthetase ATP-binding domain-like | Single hybrid motif | 4 | 2 | |
Ubiquitin-like | Thioredoxin-like | 4 | 4 | |
Ligand-binding domain in the NO signalling and Golgi transport | Nucleotide cyclase | 4 | 3 | |
Growth factor receptor domain | SAM/Pointed domain | 4 | 2 | |
Ribosomal protein S5 domain 2-like | HSP90 C-terminal domain | 4 | 4 | |
Cytokine | Cytokine | 4 | 2 | |
DBL homology domain (DH-domain) | Ras GEF | 4 | 4 | |
RNI-like | RNI-like | 4 | 4 | |
LDL receptor-like module | Growth factor receptor domain | 4 | 4 | |
ARM repeat | P-loop containing nucleoside triphosphate hydrolases | 4 | 4 | |
TPR-like | HCP-like | 4 | 4 | |
LDL receptor-like module | TSP-1 type 1 repeat | 4 | 4 | |
Phosphoglucomutase, first 3 domains | Phosphoglucomutase, C-terminal domain | 4 | 3 | |
Periplasmic binding protein-like I | Nucleotide cyclase | 4 | 4 | |
A DNA-binding domain in eukaryotic transcription factors | Leucine zipper domain | 4 | 3 | |
Terpenoid cyclases/Protein prenyltransferases | Terpenoid cyclases/Protein prenyltransferases | 4 | 3 | |
TNF receptor-like | TNF receptor-like | 4 | 4 | |
TPR-like | RING/U-box | 4 | 4 | |
ClpP/crotonase | ClpP/crotonase | 4 | 2 | |
Cullin repeat-like | Cullin homology domain | 4 | 3 | |
Zn-finger domain of Sec23/24 | Helical domain of Sec23/24 | 4 | 3 | |
FYVE/PHD zinc finger | C2 domain (Calcium/lipid-binding domain, CaLB) | 4 | 3 | |
PRTase-like | PRTase-like | 4 | 2 | |
BAR/IMD domain-like | BAR/IMD domain-like | 4 | 4 | |
PreATP-grasp domain | Single hybrid motif | 4 | 2 | |
GroES-like | GroES-like | 4 | 3 | |
DnaJ/Hsp40 cysteine-rich domain | HSP40/DnaJ peptide-binding domain | 4 | 4 | |
cAMP-binding domain-like | Ras GEF | 4 | 4 | |
Complement control module/SCR domain | Trypsin-like serine proteases | 4 | 4 | |
Regulator of G-protein signaling, RGS | Protein kinase-like (PK-like) | 4 | 4 | |
Phospholipase D/nuclease | Phospholipase D/nuclease | 4 | 2 | |
Growth factor receptor domain | Spermadhesin, CUB domain | 4 | 4 | |
WD40 repeat-like | RING/U-box | 4 | 3 | |
Acyl-CoA dehydrogenase C-terminal domain-like | Acyl-CoA dehydrogenase C-terminal domain-like | 4 | 3 | |
Spermadhesin, CUB domain | Concanavalin A-like lectins/glucanases | 4 | 4 | |
Immunoglobulin | (Phosphotyrosine protein) phosphatases II | 4 | 4 | |
HAD-like | HAD-like | 4 | 2 | |
Neurotransmitter-gated ion-channel transmembrane pore | Neurotransmitter-gated ion-channel transmembrane pore | 4 | 2 | |
C-type lectin-like | Complement control module/SCR domain | 4 | 4 | |
PAP/OAS1 substrate-binding domain | PAP/OAS1 substrate-binding domain | 4 | 4 | |
SNARE-like | Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | 4 | 2 | |
PX domain | Ubiquitin-like | 4 | 3 | |
WW domain | FF domain | 4 | 4 | |
FAS1 domain | FAS1 domain | 4 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | E set domains | 4 | 2 | |
L27 domain | SH3-domain | 4 | 2 | |
Cysteine-rich domain | GTPase activation domain, GAP | 4 | 4 | |
vWA-like | Chicken cartilage matrix protein | 4 | 4 | |
FnI-like domain | TSP-1 type 1 repeat | 4 | 4 | |
Integrin domains | EGF/Laminin | 4 | 4 | |
Ribosomal protein S5 domain 2-like | Ribonuclease PH domain 2-like | 4 | 2 | |
Retrovirus zinc finger-like domains | Retrovirus zinc finger-like domains | 4 | 4 | |
EF-G C-terminal domain-like | EF-G C-terminal domain-like | 4 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | Phosphoglycerate mutase-like | 4 | 1 | |
Second domain of FERM | Moesin tail domain | 4 | 1 | |
PDZ domain-like | WW domain | 4 | 4 | |
EGF/Laminin | TSP type-3 repeat | 4 | 4 | |
Zn-dependent exopeptidases | Carboxypeptidase regulatory domain-like | 4 | 4 | |
Growth factor receptor domain | Thyroglobulin type-1 domain | 4 | 2 | |
Second domain of FERM | PDZ domain-like | 4 | 4 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HSP90 C-terminal domain | 4 | 4 | |
Chromo domain-like | BRK domain-like | 4 | 3 | |
PH domain-like | Moesin tail domain | 4 | 1 | |
Calponin-homology domain, CH-domain | PH domain-like | 4 | 4 | |
Zn-dependent exopeptidases | Transferrin receptor-like dimerisation domain | 4 | 3 | |
WWE domain | ADP-ribosylation | 4 | 3 | |
alpha-ketoacid dehydrogenase kinase, N-terminal domain | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 4 | 2 | |
Fibronectin type III | Fibrinogen C-terminal domain-like | 4 | 4 | |
Ubiquitin-like | Moesin tail domain | 4 | 1 | |
Hemopexin-like domain | Hemopexin-like domain | 4 | 4 | |
Elafin-like | Fibronectin type III | 4 | 3 | |
Metallo-hydrolase/oxidoreductase | Metallo-hydrolase/oxidoreductase | 4 | 3 | |
CBS-domain pair | CBS-domain pair | 4 | 2 | |
Cullin homology domain | "Winged helix" DNA-binding domain | 4 | 3 | |
ALDH-like | ALDH-like | 4 | 2 | |
vWA-like | Concanavalin A-like lectins/glucanases | 4 | 3 | |
SAM/Pointed domain | PH domain-like | 4 | 4 | |
"Winged helix" DNA-binding domain | RNA-binding domain, RBD | 4 | 3 | |
Translation proteins | Ribosomal protein S5 domain 2-like | 4 | 4 | |
FAD/NAD(P)-binding domain | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 4 | 3 | |
CRAL/TRIO N-terminal domain | Supernatant protein factor (SPF), C-terminal domain | 4 | 2 | |
Rhodanese/Cell cycle control phosphatase | (Phosphotyrosine protein) phosphatases II | 4 | 3 | |
PYP-like sensor domain (PAS domain) | Voltage-gated potassium channels | 4 | 2 | |
Clathrin adaptor appendage domain | Subdomain of clathrin and coatomer appendage domain | 4 | 3 | |
Spectrin repeat | DBL homology domain (DH-domain) | 4 | 4 | |
(Trans)glycosidases | Chitinase insertion domain | 4 | 3 | |
Ankyrin repeat | SH3-domain | 4 | 3 | |
Spectrin repeat | SH3-domain | 4 | 4 | |
P-loop containing nucleoside triphosphate hydrolases | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 4 | 2 | |
TNF receptor-like | DEATH domain | 4 | 3 | |
SAM/Pointed domain | GTPase activation domain, GAP | 4 | 3 | |
Regulator of G-protein signaling, RGS | Regulator of G-protein signaling, RGS | 4 | 4 | |
Serum albumin-like | Serum albumin-like | 4 | 2 | |
Plexin repeat | EGF/Laminin | 4 | 4 | |
Translation proteins | EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain | 4 | 2 | |
DNA ligase/mRNA capping enzyme, catalytic domain | Nucleic acid-binding proteins | 4 | 4 | |
Ribonuclease H-like | DNA/RNA polymerases | 4 | 4 | |
SRCR-like | Trypsin-like serine proteases | 4 | 4 | |
CRAL/TRIO domain | Supernatant protein factor (SPF), C-terminal domain | 4 | 2 | |
PDZ domain-like | DBL homology domain (DH-domain) | 4 | 4 | |
HIN-2000 domain-like | HIN-2000 domain-like | 4 | 4 | |
KRAB domain (Kruppel-associated box) | KRAB domain (Kruppel-associated box) | 4 | 4 | |
PH domain-like | "Winged helix" DNA-binding domain | 4 | 4 | |
Enolase N-terminal domain-like | Enolase C-terminal domain-like | 4 | 2 | |
Single hybrid motif | CoA-dependent acyltransferases | 4 | 4 | |
Galactose-binding domain-like | Hect, E3 ligase catalytic domain | 3 | 3 | |
PLP-binding barrel | Alanine racemase C-terminal domain-like | 3 | 3 | |
IP3 receptor type 1 binding core, domain 2 | IP3 receptor type 1 binding core, domain 2 | 3 | 3 | |
Plexin repeat | E set domains | 3 | 3 | |
ARM repeat | PX domain | 3 | 2 | |
vWA-like | Fibronectin type III | 3 | 3 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | vWA-like | 3 | 2 | |
Concanavalin A-like lectins/glucanases | WD40 repeat-like | 3 | 3 | |
RNA-binding domain, RBD | PABC (PABP) domain | 3 | 1 | |
Spermadhesin, CUB domain | Galactose-binding domain-like | 3 | 3 | |
ThrRS/AlaRS common domain | Class II aaRS ABD-related | 3 | 3 | |
Bet v1-like | Bet v1-like | 3 | 2 | |
TSP type-3 repeat | TSP type-3 repeat | 3 | 3 | |
PR-1-like | Crisp domain-like | 3 | 2 | |
Glucocorticoid receptor-like (DNA-binding domain) | Ribonuclease H-like | 3 | 3 | |
PA domain | Transferrin receptor-like dimerisation domain | 3 | 2 | |
RuvA domain 2-like | Ribonuclease H-like | 3 | 3 | |
RCC1/BLIP-II | POZ domain | 3 | 3 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | PX domain | 3 | 2 | |
Sec63 N-terminal domain-like | E set domains | 3 | 2 | |
PDZ domain-like | SAM/Pointed domain | 3 | 3 | |
FF domain | FF domain | 3 | 3 | |
Ubiquitin-like | PDZ domain-like | 3 | 3 | |
WD40 repeat-like | Bromodomain | 3 | 2 | |
Acyl-CoA dehydrogenase NM domain-like | Acyl-CoA dehydrogenase NM domain-like | 3 | 3 | |
Kazal-type serine protease inhibitors | Immunoglobulin | 3 | 3 | |
Elafin-like | SEA domain | 3 | 2 | |
GTPase activation domain, GAP | Bet v1-like | 3 | 2 | |
SEA domain | EGF/Laminin | 3 | 2 | |
Macro domain-like | Macro domain-like | 3 | 3 | |
Somatomedin B domain | His-Me finger endonucleases | 3 | 3 | |
Ribosomal L11/L12e N-terminal domain | Ribosomal protein L11, C-terminal domain | 3 | 2 | |
E set domains | Ankyrin repeat | 3 | 2 | |
TSP-1 type 1 repeat | DEATH domain | 3 | 3 | |
Cupredoxins | Pentein | 3 | 3 | |
Clc chloride channel | Clc chloride channel | 3 | 3 | |
Concanavalin A-like lectins/glucanases | P-domain of calnexin/calreticulin | 3 | 3 | |
Ribosomal protein S5 domain 2-like | Ribosomal protein S5 domain 2-like | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 3 | 2 | |
Nucleotidyltransferase | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 3 | 1 | |
MgtE membrane domain-like | MgtE membrane domain-like | 3 | 2 | |
L domain-like | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
Elafin-like | EGF/Laminin | 3 | 2 | |
S15/NS1 RNA-binding domain | Class II aaRS ABD-related | 3 | 3 | |
Ras GEF | Ras GEF | 3 | 3 | |
Protease propeptides/inhibitors | Galactose-binding domain-like | 3 | 2 | |
CAD & PB1 domains | Protein kinase-like (PK-like) | 3 | 3 | |
TB module/8-cys domain | Growth factor receptor domain | 3 | 3 | |
BPTI-like | BPTI-like | 3 | 3 | |
Hairpin loop containing domain-like | Kringle-like | 3 | 3 | |
Periplasmic binding protein-like I | Periplasmic binding protein-like I | 3 | 3 | |
"Winged helix" DNA-binding domain | Sec63 N-terminal domain-like | 3 | 2 | |
Concanavalin A-like lectins/glucanases | FnI-like domain | 3 | 3 | |
PDZ domain-like | (Phosphotyrosine protein) phosphatases II | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | WW domain | 3 | 3 | |
DEATH domain | Immunoglobulin | 3 | 3 | |
Plexin repeat | Integrin domains | 3 | 3 | |
Folate-binding domain | Folate-binding domain | 3 | 3 | |
Sec7 domain | PH domain-like | 3 | 2 | |
SAM/Pointed domain | Bet v1-like | 3 | 2 | |
MIR domain | IP3 receptor type 1 binding core, domain 2 | 3 | 3 | |
Fibrinogen coiled-coil and central regions | Fibrinogen C-terminal domain-like | 3 | 3 | |
CRAL/TRIO domain | PH domain-like | 3 | 3 | |
Surp module (SWAP domain) | Surp module (SWAP domain) | 3 | 3 | |
Concanavalin A-like lectins/glucanases | Complement control module/SCR domain | 3 | 3 | |
E set domains | Terpenoid cyclases/Protein prenyltransferases | 3 | 3 | |
Cadherin-like | EGF/Laminin | 3 | 3 | |
PIN domain-like | 5' to 3' exonuclease, C-terminal subdomain | 3 | 2 | |
Voltage-gated potassium channels | Periplasmic binding protein-like II | 3 | 2 | |
Heat shock protein 70kD (HSP70), C-terminal subdomain | Heat shock protein 70kD (HSP70), C-terminal subdomain | 3 | 3 | |
Growth factor receptor domain | TSP-1 type 1 repeat | 3 | 3 | |
Aconitase iron-sulfur domain | LeuD/IlvD-like | 3 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | PKD domain | 3 | 3 | |
Glutathione synthetase ATP-binding domain-like | Glutathione synthetase ATP-binding domain-like | 3 | 3 | |
RNase III domain-like | dsRNA-binding domain-like | 3 | 3 | |
Cupredoxins | Peptidylarginine deiminase Pad4, middle domain | 3 | 3 | |
RING/U-box | PUA domain-like | 3 | 3 | |
Macro domain-like | ADP-ribosylation | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | GTPase activation domain, GAP | 3 | 3 | |
SEA domain | SEA domain | 3 | 2 | |
Thyroglobulin type-1 domain | EF-hand | 3 | 3 | |
"Winged helix" DNA-binding domain | Ubiquitin-like | 3 | 3 | |
L domain-like | EGF/Laminin | 3 | 3 | |
Protease propeptides/inhibitors | Subtilisin-like | 3 | 2 | |
Arginase/deacetylase | Arginase/deacetylase | 3 | 2 | |
Inhibitor of apoptosis (IAP) repeat | Inhibitor of apoptosis (IAP) repeat | 3 | 3 | |
ArfGap/RecO-like zinc finger | GTPase activation domain, GAP | 3 | 3 | |
Growth factor receptor domain | Ankyrin repeat | 3 | 3 | |
Calponin-homology domain, CH-domain | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
Formin homology 2 domain (FH2 domain) | Formin homology 2 domain (FH2 domain) | 3 | 3 | |
PKD domain | PKD domain | 3 | 3 | |
RUN domain-like | FYVE/PHD zinc finger | 3 | 2 | |
Anaphylotoxins (complement system) | Terpenoid cyclases/Protein prenyltransferases | 3 | 3 | |
PH domain-like | NAD kinase/diacylglycerol kinase-like | 3 | 3 | |
Activating enzymes of the ubiquitin-like proteins | Activating enzymes of the ubiquitin-like proteins | 3 | 2 | |
Heme-dependent peroxidases | Heme-dependent peroxidases | 3 | 3 | |
Somatomedin B domain | Alkaline phosphatase-like | 3 | 3 | |
"Winged helix" DNA-binding domain | Regulator of G-protein signaling, RGS | 3 | 2 | |
CCCH zinc finger | Retrovirus zinc finger-like domains | 3 | 2 | |
Carbonic anhydrase | Carbonic anhydrase | 3 | 3 | |
Sema domain | E set domains | 3 | 3 | |
Spectrin repeat | RING/U-box | 3 | 3 | |
Hairpin loop containing domain-like | Trypsin-like serine proteases | 3 | 3 | |
GTPase activation domain, GAP | Ubiquitin-like | 3 | 3 | |
Peptidylarginine deiminase Pad4, middle domain | Pentein | 3 | 3 | |
Frizzled cysteine-rich domain | TIMP-like | 3 | 2 | |
Ypt/Rab-GAP domain of gyp1p | EF-hand | 3 | 1 | |
RING/U-box | Fibronectin type III | 3 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Bromodomain | 3 | 2 | |
PAP/OAS1 substrate-binding domain | PAP/Archaeal CCA-adding enzyme, C-terminal domain | 3 | 1 | |
EGF/Laminin | TB module/8-cys domain | 3 | 3 | |
L domain-like | Calponin-homology domain, CH-domain | 3 | 2 | |
beta and beta-prime subunits of DNA dependent RNA-polymerase | beta and beta-prime subunits of DNA dependent RNA-polymerase | 3 | 2 | |
HLH, helix-loop-helix DNA-binding domain | Nuclear receptor coactivator interlocking domain | 3 | 1 | |
TSP-1 type 1 repeat | EGF/Laminin | 3 | 3 | |
lambda repressor-like DNA-binding domains | lambda repressor-like DNA-binding domains | 3 | 3 | |
CCHHC domain | CCHHC domain | 3 | 3 | |
Rad51 N-terminal domain-like | P-loop containing nucleoside triphosphate hydrolases | 3 | 1 | |
Nucleoside diphosphate kinase, NDK | Nucleoside diphosphate kinase, NDK | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | TPR-like | 3 | 3 | |
Concanavalin A-like lectins/glucanases | Fibrinogen C-terminal domain-like | 3 | 3 | |
ARM repeat | Subdomain of clathrin and coatomer appendage domain | 3 | 2 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | N-terminal nucleophile aminohydrolases (Ntn hydrolases) | 3 | 2 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | C-terminal domain of alpha and beta subunits of F1 ATP synthase | 3 | 2 | |
C-type lectin-like | Spermadhesin, CUB domain | 3 | 3 | |
Rap/Ran-GAP | PDZ domain-like | 3 | 2 | |
"Winged helix" DNA-binding domain | SMAD/FHA domain | 3 | 1 | |
TB module/8-cys domain | TB module/8-cys domain | 3 | 3 | |
BAR/IMD domain-like | ArfGap/RecO-like zinc finger | 3 | 2 | |
Ubiquitin-like | Cysteine proteinases | 3 | 3 | |
BAR/IMD domain-like | Ankyrin repeat | 3 | 2 | |
NAD(P)-linked oxidoreductase | NAD(P)-linked oxidoreductase | 3 | 1 | |
EF-hand | NAD kinase/diacylglycerol kinase-like | 3 | 2 | |
Class II aaRS and biotin synthetases | Class II aaRS and biotin synthetases | 3 | 3 | |
PA domain | Zn-dependent exopeptidases | 3 | 2 | |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Lipoxigenase | 3 | 2 | |
TGS-like | ThrRS/AlaRS common domain | 3 | 3 | |
Immunoglobulin | C-type lectin-like | 3 | 2 | |
Second domain of FERM | Protein kinase-like (PK-like) | 3 | 3 | |
Lipoxigenase | Lipoxigenase | 3 | 2 | |
Metalloproteases ("zincins"), catalytic domain | Concanavalin A-like lectins/glucanases | 3 | 3 | |
ARM repeat | BEACH domain | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | EF-hand | 3 | 3 | |
Metalloproteases ("zincins"), catalytic domain | EGF/Laminin | 3 | 3 | |
PHM/PNGase F | PHM/PNGase F | 3 | 3 | |
NAD(P)-binding Rossmann-fold domains | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 3 | 2 | |
Protein kinase-like (PK-like) | NTF2-like | 3 | 3 | |
RNA-binding domain, RBD | Ran binding protein zinc finger-like | 3 | 2 | |
Protein kinase-like (PK-like) | Polo-box domain | 3 | 2 | |
ACT-like | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 3 | 3 | |
"Winged helix" DNA-binding domain | FYVE/PHD zinc finger | 3 | 2 | |
Galactose-binding domain-like | (Trans)glycosidases | 3 | 2 | |
(Phosphotyrosine protein) phosphatases II | SH2 domain | 3 | 3 | |
RING/U-box | TRAF domain-like | 3 | 3 | |
Peptidase/esterase 'gauge' domain | alpha/beta-Hydrolases | 3 | 2 | |
B-box zinc-binding domain | Fibronectin type III | 3 | 1 | |
SH2 domain | GTPase activation domain, GAP | 3 | 3 | |
PH domain-like | Ypt/Rab-GAP domain of gyp1p | 3 | 3 | |
TATA-box binding protein-like | TATA-box binding protein-like | 3 | 2 | |
Galactose mutarotase-like | Trefoil | 3 | 3 | |
SH2 domain | C2 domain (Calcium/lipid-binding domain, CaLB) | 3 | 3 | |
P-loop containing nucleoside triphosphate hydrolases | FYVE/PHD zinc finger | 3 | 3 | |
t-snare proteins | SNARE fusion complex | 3 | 2 | |
EGF/Laminin | Ankyrin repeat | 3 | 3 | |
Sialidases | Sialidases | 3 | 2 | |
Tudor/PWWP/MBT | SET domain | 3 | 1 | |
Ras GEF | EF-hand | 3 | 3 | |
DNA/RNA polymerases | Lesion bypass DNA polymerase (Y-family), little finger domain | 3 | 2 | |
Metallo-dependent phosphatases | Metallo-dependent phosphatases | 3 | 3 | |
S15/NS1 RNA-binding domain | Class II aaRS and biotin synthetases | 3 | 3 | |
Pectin lyase-like | Pectin lyase-like | 3 | 3 | |
RING/U-box | NHL repeat | 3 | 2 | |
EF-hand | Mitochondrial carrier | 3 | 2 | |
cAMP-binding domain-like | Ubiquitin-like | 3 | 3 | |
DBL homology domain (DH-domain) | FYVE/PHD zinc finger | 3 | 2 | |
Sema domain | GTPase activation domain, GAP | 3 | 3 | |
DNA polymerase beta, N-terminal domain-like | Nucleotidyltransferase | 3 | 3 | |
Tudor/PWWP/MBT | P-loop containing nucleoside triphosphate hydrolases | 3 | 3 | |
MOSC N-terminal domain-like | PK beta-barrel domain-like | 3 | 3 | |
Creatinase/prolidase N-terminal domain | Creatinase/aminopeptidase | 3 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | POZ domain | 3 | 2 | |
RNI-like | ARM repeat | 3 | 1 | |
WD40 repeat-like | FYVE/PHD zinc finger | 3 | 3 | |
ATP-dependent DNA ligase DNA-binding domain | Nucleic acid-binding proteins | 3 | 3 | |
B-box zinc-binding domain | NHL repeat | 3 | 2 | |
HSP20-like chaperones | HSP20-like chaperones | 3 | 2 | |
PYP-like sensor domain (PAS domain) | Nuclear receptor coactivator interlocking domain | 3 | 1 | |
Plakin repeat | Spectrin repeat | 3 | 3 | |
Fibronectin type III | SEA domain | 3 | 2 | |
ATP-dependent DNA ligase DNA-binding domain | DNA ligase/mRNA capping enzyme, catalytic domain | 3 | 3 | |
vWA-like | Integrin beta tail domain | 3 | 3 | |
CRAL/TRIO domain | Spectrin repeat | 3 | 3 | |
PDZ domain-like | C2 domain (Calcium/lipid-binding domain, CaLB) | 3 | 2 | |
RING/U-box | Ankyrin repeat | 3 | 3 | |
CRAL/TRIO domain | DBL homology domain (DH-domain) | 3 | 3 | |
Periplasmic binding protein-like I | Voltage-gated potassium channels | 3 | 2 | |
FnI-like domain | EGF/Laminin | 3 | 3 | |
Ricin B-like lectins | C-type lectin-like | 3 | 3 | |
Alkaline phosphatase-like | His-Me finger endonucleases | 3 | 3 | |
Tropomyosin | Tropomyosin | 3 | 2 | |
RNA-binding domain, RBD | SPOC domain-like | 3 | 3 | |
Regulator of G-protein signaling, RGS | PH domain-like | 3 | 3 | |
Growth factor receptor domain | Chicken cartilage matrix protein | 3 | 3 | |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | P-loop containing nucleoside triphosphate hydrolases | 3 | 2 | |
Domain of poly(ADP-ribose) polymerase | ADP-ribosylation | 3 | 3 | |
WWE domain | RING/U-box | 3 | 2 | |
Concanavalin A-like lectins/glucanases | EF-hand | 2 | 2 | |
UBC-like | Endosomal sorting complex assembly domain | 2 | 1 | |
Plexin repeat | Immunoglobulin | 2 | 1 | |
PAP/OAS1 substrate-binding domain | Retrovirus zinc finger-like domains | 2 | 2 | |
"Winged helix" DNA-binding domain | E set domains | 2 | 1 | |
BRCT domain | Nucleotidyltransferase | 2 | 2 | |
MIT domain | P-loop containing nucleoside triphosphate hydrolases | 2 | 1 | |
Ricin B-like lectins | Kringle-like | 2 | 2 | |
"Winged helix" DNA-binding domain | Transducin (heterotrimeric G protein), gamma chain | 2 | 1 | |
DNA ligase/mRNA capping enzyme, catalytic domain | BRCT domain | 2 | 2 | |
WD40 repeat-like | SOCS box-like | 2 | 2 | |
Fibronectin type III | BPTI-like | 2 | 2 | |
POZ domain | Galactose oxidase, central domain | 2 | 2 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | 6-phosphogluconate dehydrogenase C-terminal domain-like | 2 | 2 | |
SRCR-like | LDL receptor-like module | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | RING/U-box | 2 | 2 | |
GLA-domain | EGF/Laminin | 2 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | Type II DNA topoisomerase | 2 | 2 | |
DNase I-like | GTPase activation domain, GAP | 2 | 1 | |
HMA, heavy metal-associated domain | HMA, heavy metal-associated domain | 2 | 2 | |
Anaphylotoxins (complement system) | Alpha-macroglobulin receptor domain | 2 | 2 | |
NAD(P)-binding Rossmann-fold domains | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
ClpP/crotonase | 6-phosphogluconate dehydrogenase C-terminal domain-like | 2 | 2 | |
POZ domain | Galactose-binding domain-like | 2 | 1 | |
Cupredoxins | Galactose-binding domain-like | 2 | 2 | |
Nucleotide-binding domain | FAD-linked reductases, C-terminal domain | 2 | 1 | |
EGF/Laminin | Notch domain | 2 | 2 | |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Zinc beta-ribbon | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | Succinyl-CoA synthetase domains | 2 | 2 | |
EF-hand | C-terminal domain of PLC-beta | 2 | 1 | |
Kringle-like | C-type lectin-like | 2 | 2 | |
A middle domain of Talin 1 | alpha-catenin/vinculin-like | 2 | 2 | |
N-terminal domain of cbl (N-cbl) | SH2 domain | 2 | 2 | |
Regulator of G-protein signaling, RGS | DBL homology domain (DH-domain) | 2 | 2 | |
Integrin domains | Integrin beta tail domain | 2 | 2 | |
DNA-binding domain | FYVE/PHD zinc finger | 2 | 2 | |
Chitinase insertion domain | Invertebrate chitin-binding proteins | 2 | 1 | |
RUN domain-like | RUN domain-like | 2 | 1 | |
PH domain-like | A middle domain of Talin 1 | 2 | 2 | |
TGS-like | Class II aaRS and biotin synthetases | 2 | 2 | |
YWTD domain | Fibronectin type III | 2 | 2 | |
PriA/YqbF domain | GINS helical bundle-like | 2 | 2 | |
DBL homology domain (DH-domain) | C2 domain (Calcium/lipid-binding domain, CaLB) | 2 | 2 | |
Ferritin-like | Ferritin-like | 2 | 1 | |
Chromo domain-like | SET domain | 2 | 1 | |
Nucleic acid-binding proteins | Translation proteins SH3-like domain | 2 | 1 | |
G protein-binding domain | G protein-binding domain | 2 | 1 | |
Ribonuclease H-like | RNA-binding domain, RBD | 2 | 2 | |
RNA-binding domain, RBD | Cyclophilin-like | 2 | 2 | |
Concanavalin A-like lectins/glucanases | TRAF domain-like | 2 | 2 | |
Tex N-terminal region-like | RuvA domain 2-like | 2 | 2 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | VPS9 domain | 2 | 2 | |
Protein kinase-like (PK-like) | FAT domain of focal adhesion kinase | 2 | 2 | |
TAZ domain | Bromodomain | 2 | 2 | |
LCCL domain | vWA-like | 2 | 2 | |
Ribonuclease H-like | HRDC-like | 2 | 2 | |
GFP-like | EGF/Laminin | 2 | 2 | |
Single hybrid motif | Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | 2 | 2 | |
Clavaminate synthase-like | RNI-like | 2 | 2 | |
Flavoproteins | Ferredoxin reductase-like, C-terminal NADP-linked domain | 2 | 2 | |
RING/U-box | Homeodomain-like | 2 | 2 | |
TRAF domain-like | EGF/Laminin | 2 | 2 | |
Telomeric repeat binding factor (TRF) dimerisation domain | Homeodomain-like | 2 | 2 | |
Heme-dependent peroxidases | EF-hand | 2 | 2 | |
Inhibitor of apoptosis (IAP) repeat | DEATH domain | 2 | 2 | |
TSP-1 type 1 repeat | TSP type-3 repeat | 2 | 2 | |
Multidrug resistance efflux transporter EmrE | Multidrug resistance efflux transporter EmrE | 2 | 2 | |
Notch domain | Ankyrin repeat | 2 | 2 | |
WGR domain-like | ADP-ribosylation | 2 | 2 | |
Tudor/PWWP/MBT | Chromo domain-like | 2 | 1 | |
Creatinase/aminopeptidase | "Winged helix" DNA-binding domain | 2 | 2 | |
TAZ domain | TAZ domain | 2 | 2 | |
A middle domain of Talin 1 | I/LWEQ domain | 2 | 2 | |
Amyloid beta a4 protein copper binding domain (domain 2) | CAPPD, an extracellular domain of amyloid beta A4 protein | 2 | 1 | |
EGF/Laminin | Chicken cartilage matrix protein | 2 | 2 | |
SMAD/FHA domain | PH domain-like | 2 | 2 | |
Thyroglobulin type-1 domain | Thyroglobulin type-1 domain | 2 | 2 | |
Calponin-homology domain, CH-domain | Glucocorticoid receptor-like (DNA-binding domain) | 2 | 2 | |
Protein kinase-like (PK-like) | G protein-binding domain | 2 | 2 | |
SH3-domain | ARM repeat | 2 | 1 | |
Alpha-macroglobulin receptor domain | TIMP-like | 2 | 2 | |
Calponin-homology domain, CH-domain | RGC domain-like | 2 | 2 | |
Domain of the SRP/SRP receptor G-proteins | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
DBL homology domain (DH-domain) | DBL homology domain (DH-domain) | 2 | 2 | |
dsRNA-binding domain-like | Ribosomal protein S5 domain 2-like | 2 | 1 | |
Calponin-homology domain, CH-domain | SH3-domain | 2 | 2 | |
DEATH domain | DEATH domain | 2 | 1 | |
HAND domain of the nucleosome remodeling ATPase ISWI | Homeodomain-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | TGS-like | 2 | 1 | |
Tudor/PWWP/MBT | ARID-like | 2 | 1 | |
SH3-domain | PX domain | 2 | 2 | |
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | Aromatic aminoacid monoxygenases, catalytic and oligomerization domains | 2 | 2 | |
RNA-binding domain, RBD | Eukaryotic type KH-domain (KH-domain type I) | 2 | 2 | |
Spermadhesin, CUB domain | Cystine-knot cytokines | 2 | 1 | |
SET domain | beta-beta-alpha zinc fingers | 2 | 2 | |
Ypt/Rab-GAP domain of gyp1p | Rhodanese/Cell cycle control phosphatase | 2 | 2 | |
PR-1-like | LCCL domain | 2 | 1 | |
SH3-domain | WW domain | 2 | 2 | |
PsbU/PolX domain-like | Nucleotidyltransferase | 2 | 2 | |
PLC-like phosphodiesterases | SH2 domain | 2 | 2 | |
Glucocorticoid receptor-like (DNA-binding domain) | VHP, Villin headpiece domain | 2 | 2 | |
Calpain large subunit, middle domain (domain III) | Calpain large subunit, middle domain (domain III) | 2 | 2 | |
beta-N-acetylhexosaminidase-like domain | (Trans)glycosidases | 2 | 2 | |
Plexin repeat | Integrin beta tail domain | 2 | 2 | |
CO dehydrogenase ISP C-domain like | CO dehydrogenase flavoprotein C-terminal domain-like | 2 | 2 | |
ARM repeat | UBA-like | 2 | 2 | |
WW domain | NAD(P)-binding Rossmann-fold domains | 2 | 2 | |
HMA, heavy metal-associated domain | Calcium ATPase, transduction domain A | 2 | 2 | |
E set domains | Pectin lyase-like | 2 | 2 | |
LDL receptor-like module | Family A G protein-coupled receptor-like | 2 | 2 | |
Colipase-like | Colipase-like | 2 | 1 | |
Phosphofructokinase | Phosphofructokinase | 2 | 2 | |
Spectrin repeat | Protein kinase-like (PK-like) | 2 | 2 | |
Rap30/74 interaction domains | "Winged helix" DNA-binding domain | 2 | 2 | |
PA domain | RING/U-box | 2 | 2 | |
RuvA domain 2-like | Nucleic acid-binding proteins | 2 | 2 | |
Metalloproteases ("zincins"), catalytic domain | ARM repeat | 2 | 2 | |
Protein kinase-like (PK-like) | RCC1/BLIP-II | 2 | 2 | |
Transducin (heterotrimeric G protein), gamma chain | Regulator of G-protein signaling, RGS | 2 | 1 | |
WGR domain-like | Domain of poly(ADP-ribose) polymerase | 2 | 2 | |
PDZ domain-like | Regulator of G-protein signaling, RGS | 2 | 2 | |
Ubiquitin-like | alpha-catenin/vinculin-like | 2 | 2 | |
RUN domain-like | PH domain-like | 2 | 1 | |
Spermadhesin, CUB domain | LCCL domain | 2 | 2 | |
Kix domain of CBP (creb binding protein) | Bromodomain | 2 | 2 | |
DBL homology domain (DH-domain) | "Winged helix" DNA-binding domain | 2 | 2 | |
Immunoglobulin | EGF/Laminin | 2 | 2 | |
Cysteine-rich domain | DBL homology domain (DH-domain) | 2 | 2 | |
Serine protease inhibitors | FnI-like domain | 2 | 2 | |
UBA-like | Cysteine proteinases | 2 | 2 | |
FAD/NAD(P)-binding domain | Calponin-homology domain, CH-domain | 2 | 2 | |
NAD kinase/diacylglycerol kinase-like | NAD kinase/diacylglycerol kinase-like | 2 | 2 | |
Hormone receptor domain | Family A G protein-coupled receptor-like | 2 | 2 | |
LCCL domain | LCCL domain | 2 | 1 | |
Anaphylotoxins (complement system) | TIMP-like | 2 | 2 | |
PH domain-like | I/LWEQ domain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | HAND domain of the nucleosome remodeling ATPase ISWI | 2 | 2 | |
PEP carboxykinase N-terminal domain | PEP carboxykinase-like | 2 | 2 | |
Second domain of FERM | I/LWEQ domain | 2 | 2 | |
Cap-Gly domain | Cap-Gly domain | 2 | 2 | |
ClpP/crotonase | NAD(P)-binding Rossmann-fold domains | 2 | 2 | |
NagB/RpiA/CoA transferase-like | NagB/RpiA/CoA transferase-like | 2 | 2 | |
Homeodomain-like | FAD-linked reductases, C-terminal domain | 2 | 2 | |
ATP-dependent DNA ligase DNA-binding domain | BRCT domain | 2 | 2 | |
NAD(P)-binding Rossmann-fold domains | SCP-like | 2 | 2 | |
PLC-like phosphodiesterases | C-terminal domain of PLC-beta | 2 | 1 | |
dsRNA-binding domain-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Serine protease inhibitors | Serine protease inhibitors | 2 | 2 | |
Nucleic acid-binding proteins | BRCT domain | 2 | 2 | |
WW domain | GTPase activation domain, GAP | 2 | 2 | |
Flavoproteins | Riboflavin synthase domain-like | 2 | 2 | |
FKBP-like | FKBP-like | 2 | 2 | |
Annexin | Annexin | 2 | 2 | |
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | DNA breaking-rejoining enzymes | 2 | 1 | |
UBA-like | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
Tex N-terminal region-like | Nucleic acid-binding proteins | 2 | 2 | |
Sema domain | Sema domain | 2 | 2 | |
RING/U-box | BRCT domain | 2 | 2 | |
DPP6 N-terminal domain-like | WD40 repeat-like | 2 | 2 | |
G protein-binding domain | Cysteine-rich domain | 2 | 2 | |
Second domain of FERM | A middle domain of Talin 1 | 2 | 2 | |
G protein-binding domain | PH domain-like | 2 | 2 | |
Concanavalin A-like lectins/glucanases | PH domain-like | 2 | 2 | |
Myosin rod fragments | Tropomyosin | 2 | 2 | |
Ubiquitin-like | XPC-binding domain | 2 | 2 | |
Chromo domain-like | ClpP/crotonase | 2 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Initiation factor IF2/eIF5b, domain 3 | 2 | 2 | |
Glycosyl hydrolase domain | Trefoil | 2 | 2 | |
Ankyrin repeat | TPR-like | 2 | 2 | |
Plakin repeat | EF-hand | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Homeodomain-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Fzo-like conserved region | 2 | 2 | |
E set domains | Alpha-macroglobulin receptor domain | 2 | 2 | |
Glucocorticoid receptor-like (DNA-binding domain) | Protein kinase-like (PK-like) | 2 | 2 | |
Dimerization-anchoring domain of cAMP-dependent PK regulatory subunit | cAMP-binding domain-like | 2 | 1 | |
Cyclophilin-like | TPR-like | 2 | 2 | |
Plakin repeat | Plakin repeat | 2 | 2 | |
TPR-like | Clavaminate synthase-like | 2 | 2 | |
SH2 domain | RING/U-box | 2 | 2 | |
I/LWEQ domain | I/LWEQ domain | 2 | 2 | |
Fibronectin type III | Ankyrin repeat | 2 | 2 | |
ARM repeat | Concanavalin A-like lectins/glucanases | 2 | 2 | |
Chaperone J-domain | DnaJ/Hsp40 cysteine-rich domain | 2 | 2 | |
Tex N-terminal region-like | Ribonuclease H-like | 2 | 2 | |
Seven-hairpin glycosidases | Seven-hairpin glycosidases | 2 | 2 | |
CO dehydrogenase flavoprotein C-terminal domain-like | Molybdenum cofactor-binding domain | 2 | 2 | |
Nucleotidyltransferase | Retrovirus zinc finger-like domains | 2 | 2 | |
t-snare proteins | t-snare proteins | 2 | 1 | |
Metalloproteases ("zincins"), catalytic domain | TRAF domain-like | 2 | 2 | |
WD40 repeat-like | SNARE fusion complex | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Class I glutamine amidotransferase-like | 2 | 2 | |
Acyl-CoA N-acyltransferases (Nat) | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 | |
E set domains | GTPase activation domain, GAP | 2 | 2 | |
E set domains | Anthrax protective antigen | 2 | 2 | |
EF-hand | GAS2 domain-like | 2 | 2 | |
Amyloid beta a4 protein copper binding domain (domain 2) | BPTI-like | 2 | 1 | |
SWIB/MDM2 domain | Ran binding protein zinc finger-like | 2 | 2 | |
TAZ domain | RING/U-box | 2 | 2 | |
TAFH domain-like | HIT/MYND zinc finger-like | 2 | 1 | |
TPR-like | ARM repeat | 2 | 2 | |
BRCT domain | DNA polymerase beta, N-terminal domain-like | 2 | 2 | |
Citrate synthase | Citrate synthase | 2 | 2 | |
RCC1/BLIP-II | Galactose-binding domain-like | 2 | 2 | |
Bromodomain | RING/U-box | 2 | 2 | |
Tudor/PWWP/MBT | Cullin homology domain | 2 | 2 | |
N-terminal domain of adenylylcyclase associated protein, CAP | C-terminal domain of adenylylcyclase associated protein | 2 | 1 | |
Prefoldin | Intermediate filament protein, coiled coil region | 2 | 2 | |
Protein kinase-like (PK-like) | Tricorn protease domain 2 | 2 | 2 | |
GLA-domain | Trypsin-like serine proteases | 2 | 1 | |
N-acetylmuramoyl-L-alanine amidase-like | N-acetylmuramoyl-L-alanine amidase-like | 2 | 2 | |
Second domain of FERM | alpha-catenin/vinculin-like | 2 | 2 | |
Aquaporin-like | Aquaporin-like | 2 | 1 | |
Kelch motif | C-type lectin-like | 2 | 2 | |
Mib/herc2 domain-like | Hect, E3 ligase catalytic domain | 2 | 2 | |
MIR domain | EF-hand | 2 | 2 | |
BPTI-like | CAPPD, an extracellular domain of amyloid beta A4 protein | 2 | 1 | |
Histone-fold | DBL homology domain (DH-domain) | 2 | 2 | |
(Phosphotyrosine protein) phosphatases II | FYVE/PHD zinc finger | 2 | 2 | |
DBL homology domain (DH-domain) | Protein kinase-like (PK-like) | 2 | 2 | |
Rudiment single hybrid motif | ClpP/crotonase | 2 | 1 | |
Second domain of FERM | FAT domain of focal adhesion kinase | 2 | 2 | |
Metalloproteases ("zincins"), catalytic domain | Kringle-like | 2 | 2 | |
Ras GEF | Cysteine-rich domain | 2 | 2 | |
TRAF domain-like | POZ domain | 2 | 1 | |
Galactose-binding domain-like | Zn-dependent exopeptidases | 2 | 2 | |
ARID-like | FYVE/PHD zinc finger | 2 | 2 | |
Phosphoglycerate mutase-like | Phosphoglycerate mutase-like | 2 | 2 | |
Ubiquitin-like | RING/U-box | 2 | 2 | |
Voltage-gated potassium channels | NAD(P)-binding Rossmann-fold domains | 2 | 1 | |
HR1 repeat | Protein kinase-like (PK-like) | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | FF domain | 2 | 2 | |
PYP-like sensor domain (PAS domain) | HD-domain/PDEase-like | 2 | 1 | |
ARID-like | Clavaminate synthase-like | 2 | 2 | |
Peripheral subunit-binding domain of 2-oxo acid dehydrogenase complex | CoA-dependent acyltransferases | 2 | 2 | |
DNA-binding domain | Bromodomain | 2 | 2 | |
ARM repeat | RING/U-box | 2 | 2 | |
Calponin-homology domain, CH-domain | Calponin-homology domain, CH-domain | 2 | 2 | |
RING/U-box | UBA-like | 2 | 2 | |
Histone-fold | PH domain-like | 2 | 2 | |
Translational machinery components | L30e-like | 2 | 2 | |
Translation proteins | Initiation factor IF2/eIF5b, domain 3 | 2 | 2 | |
TPR-like | Chaperone J-domain | 2 | 2 | |
FMT C-terminal domain-like | ALDH-like | 2 | 2 | |
Eukaryotic DNA topoisomerase I, N-terminal DNA-binding fragment | Eukaryotic DNA topoisomerase I, dispensable insert domain | 2 | 1 | |
Insert subdomain of RNA polymerase alpha subunit | RBP11-like subunits of RNA polymerase | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | HRDC-like | 2 | 2 | |
CO dehydrogenase flavoprotein C-terminal domain-like | CO dehydrogenase molybdoprotein N-domain-like | 2 | 2 | |
GFP-like | Growth factor receptor domain | 2 | 2 | |
BRCT domain | ADP-ribosylation | 2 | 2 | |
beta-beta-alpha zinc fingers | Leucine zipper domain | 2 | 1 | |
Mob1/phocein | Mob1/phocein | 2 | 1 | |
TGS-like | Class II aaRS ABD-related | 2 | 2 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | C-terminal domain of PLC-beta | 2 | 1 | |
LDL receptor-like module | L domain-like | 2 | 2 | |
Ubiquitin-like | Cysteine-rich domain | 2 | 2 | |
Ribonuclease H-like | Nucleic acid-binding proteins | 2 | 2 | |
Cysteine-rich domain | SH3-domain | 2 | 2 | |
Carbonic anhydrase | (Phosphotyrosine protein) phosphatases II | 2 | 2 | |
Clavaminate synthase-like | Tudor/PWWP/MBT | 2 | 2 | |
Galactose-binding domain-like | Fibrinogen C-terminal domain-like | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | RNA-binding domain, RBD | 2 | 2 | |
Assembly domain of cartilage oligomeric matrix protein | EGF/Laminin | 2 | 2 | |
SPOC domain-like | SPOC domain-like | 2 | 2 | |
Mib/herc2 domain-like | Ankyrin repeat | 2 | 2 | |
A heparin-binding domain | BPTI-like | 2 | 1 | |
FYVE/PHD zinc finger | RING/U-box | 2 | 2 | |
TSP-1 type 1 repeat | Complement control module/SCR domain | 2 | 2 | |
GTPase activation domain, GAP | GTPase activation domain, GAP | 2 | 2 | |
Molybdenum cofactor-binding domain | Molybdenum cofactor-binding domain | 2 | 2 | |
BRK domain-like | BRK domain-like | 2 | 1 | |
Multidrug efflux transporter AcrB transmembrane domain | Multidrug efflux transporter AcrB transmembrane domain | 2 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | AN1-like Zinc finger | 2 | 2 | |
ARM repeat | "Winged helix" DNA-binding domain | 2 | 1 | |
ARM repeat | WWE domain | 2 | 2 | |
PH domain-like | alpha-catenin/vinculin-like | 2 | 2 | |
PreATP-grasp domain | ClpP/crotonase | 2 | 1 | |
Putative DNA-binding domain | SAND domain-like | 2 | 2 | |
GAT-like domain | Clathrin adaptor appendage domain | 2 | 2 | |
PP2C-like | Protein serine/threonine phosphatase 2C, C-terminal domain | 2 | 2 | |
CO dehydrogenase ISP C-domain like | CO dehydrogenase molybdoprotein N-domain-like | 2 | 2 | |
SH3-domain | Phosphoglycerate mutase-like | 2 | 2 | |
Concanavalin A-like lectins/glucanases | LDL receptor-like module | 2 | 2 | |
EGF/Laminin | Kazal-type serine protease inhibitors | 2 | 2 | |
E set domains | NHL repeat | 2 | 2 | |
POZ domain | A DNA-binding domain in eukaryotic transcription factors | 2 | 2 | |
Kazal-type serine protease inhibitors | Thyroglobulin type-1 domain | 2 | 2 | |
"Winged helix" DNA-binding domain | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 | |
Prefoldin | WD40 repeat-like | 2 | 1 | |
Assembly domain of cartilage oligomeric matrix protein | Concanavalin A-like lectins/glucanases | 2 | 2 | |
A heparin-binding domain | Amyloid beta a4 protein copper binding domain (domain 2) | 2 | 1 | |
Ankyrin repeat | Hect, E3 ligase catalytic domain | 2 | 2 | |
UDP-Glycosyltransferase/glycogen phosphorylase | UDP-Glycosyltransferase/glycogen phosphorylase | 2 | 1 | |
RING/U-box | SH3-domain | 2 | 2 | |
Somatomedin B domain | Somatomedin B domain | 2 | 2 | |
PLC-like phosphodiesterases | SH3-domain | 2 | 2 | |
EGF/Laminin | Integrin beta tail domain | 2 | 2 | |
EF-hand | DBL homology domain (DH-domain) | 2 | 2 | |
Homeodomain-like | FAD/NAD(P)-binding domain | 2 | 2 | |
Ankyrin repeat | POZ domain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | FtsH protease domain-like | 2 | 2 | |
HMA, heavy metal-associated domain | HAD-like | 2 | 2 | |
(Trans)glycosidases | Trefoil | 2 | 2 | |
Nucleotidylyl transferase | Ribosomal protein L25-like | 2 | 2 | |
Calponin-homology domain, CH-domain | GTPase activation domain, GAP | 2 | 2 | |
Cation efflux protein transmembrane domain-like | Cation efflux protein cytoplasmic domain-like | 2 | 2 | |
WD40 repeat-like | YVTN repeat-like/Quinoprotein amine dehydrogenase | 2 | 2 | |
FAD/NAD(P)-binding domain | Folate-binding domain | 2 | 2 | |
beta-beta-alpha zinc fingers | RNA-binding domain, RBD | 2 | 2 | |
Folate-binding domain | Aminomethyltransferase beta-barrel domain | 2 | 2 | |
UBC-like | UBC-like | 2 | 1 | |
Nicotinate/Quinolinate PRTase N-terminal domain-like | Nicotinate/Quinolinate PRTase C-terminal domain-like | 2 | 2 | |
FnI-like domain | Kringle-like | 2 | 2 | |
Galactose-binding domain-like | Mib/herc2 domain-like | 2 | 2 | |
Sec7 domain | ARM repeat | 2 | 2 | |
Ankyrin repeat | Eukaryotic type KH-domain (KH-domain type I) | 2 | 2 | |
beta-lactamase/transpeptidase-like | Ankyrin repeat | 2 | 1 | |
Periplasmic binding protein-like II | Periplasmic binding protein-like II | 2 | 1 | |
Chaperone J-domain | Thioredoxin-like | 2 | 2 | |
Growth factor receptor domain | Notch domain | 2 | 2 | |
Kelch motif | Galactose oxidase, central domain | 2 | 2 | |
Spectrin repeat | Immunoglobulin | 2 | 2 | |
Nicotinic receptor ligand binding domain-like | Nicotinic receptor ligand binding domain-like | 2 | 1 | |
Anthrax protective antigen | Pectin lyase-like | 2 | 2 | |
Sec63 N-terminal domain-like | Sec63 N-terminal domain-like | 2 | 1 | |
Second domain of FERM | DBL homology domain (DH-domain) | 2 | 2 | |
Clavaminate synthase-like | Clavaminate synthase-like | 2 | 2 | |
Ubiquitin-like | I/LWEQ domain | 2 | 2 | |
SMAD/FHA domain | RING/U-box | 2 | 2 | |
NTF2-like | RNA-binding domain, RBD | 2 | 2 | |
TPR-like | PUA domain-like | 2 | 2 | |
MIR domain | Concanavalin A-like lectins/glucanases | 2 | 2 | |
Single hybrid motif | ClpP/crotonase | 2 | 1 | |
ArfGap/RecO-like zinc finger | SH3-domain | 2 | 1 | |
Calponin-homology domain, CH-domain | E set domains | 2 | 2 | |
RNA-binding domain, RBD | dsRNA-binding domain-like | 2 | 2 | |
FYVE/PHD zinc finger | Acyl-CoA N-acyltransferases (Nat) | 2 | 1 | |
Staphylococcal nuclease | Tudor/PWWP/MBT | 2 | 2 | |
WWE domain | Hect, E3 ligase catalytic domain | 2 | 2 | |
RuvA domain 2-like | RuvA domain 2-like | 2 | 2 | |
CCCH zinc finger | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
PH domain-like | C-terminal domain of PLC-beta | 2 | 1 | |
SNARE fusion complex | SNARE fusion complex | 2 | 1 | |
Adenine nucleotide alpha hydrolases-like | Adenine nucleotide alpha hydrolases-like | 2 | 2 | |
Concanavalin A-like lectins/glucanases | TSP-1 type 1 repeat | 2 | 2 | |
PH domain-like | FAT domain of focal adhesion kinase | 2 | 2 | |
Glutathione synthetase ATP-binding domain-like | ClpP/crotonase | 2 | 1 | |
DBL homology domain (DH-domain) | Immunoglobulin | 2 | 2 | |
N-terminal domain of cbl (N-cbl) | RING/U-box | 2 | 2 | |
I/LWEQ domain | alpha-catenin/vinculin-like | 2 | 2 | |
"Winged helix" DNA-binding domain | Ras GEF | 2 | 2 | |
SAND domain-like | FYVE/PHD zinc finger | 2 | 2 | |
Cryptochrome/photolyase, N-terminal domain | Cryptochrome/photolyase FAD-binding domain | 2 | 1 | |
ARM repeat | Hect, E3 ligase catalytic domain | 2 | 2 | |
BRCT domain | Domain of poly(ADP-ribose) polymerase | 2 | 2 | |
Glutamine synthetase, N-terminal domain | Glutamine synthetase/guanido kinase | 2 | 2 | |
Histone-fold | Macro domain-like | 2 | 2 | |
L27 domain | L27 domain | 2 | 2 | |
Concanavalin A-like lectins/glucanases | (Phosphotyrosine protein) phosphatases II | 2 | 2 | |
Ankyrin repeat | ADP-ribosylation | 2 | 2 | |
Ubiquitin-like | SH2 domain | 2 | 1 | |
GFP-like | YWTD domain | 2 | 2 | |
B-box zinc-binding domain | Bromodomain | 2 | 2 | |
Pentein | Pentein | 2 | 2 | |
Calponin-homology domain, CH-domain | RING/U-box | 2 | 2 | |
CRAL/TRIO domain | Immunoglobulin | 2 | 2 | |
PH domain-like | Vasodilator-stimulated phosphoprotein, VASP, tetramerisation domain | 2 | 1 | |
SAM/Pointed domain | ADP-ribosylation | 2 | 2 | |
Elafin-like | BPTI-like | 2 | 2 | |
vWA-like | BPTI-like | 2 | 2 | |
TRAF domain-like | TRAF domain-like | 2 | 2 | |
Growth factor receptor domain | Mannose 6-phosphate receptor domain | 2 | 1 | |
CRAL/TRIO domain | Protein kinase-like (PK-like) | 2 | 2 | |
EGF/Laminin | Heme-dependent peroxidases | 2 | 2 | |
Spectrin repeat | GAS2 domain-like | 2 | 2 | |
CO dehydrogenase molybdoprotein N-domain-like | Molybdenum cofactor-binding domain | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Prefoldin | 2 | 1 | |
GTPase activation domain, GAP | RGC domain-like | 2 | 2 | |
L domain-like | PDZ domain-like | 2 | 2 | |
Galactose-binding domain-like | Carboxypeptidase regulatory domain-like | 2 | 2 | |
PLP-binding barrel | PLP-binding barrel | 2 | 2 | |
PDZ domain-like | "Winged helix" DNA-binding domain | 2 | 2 | |
FnI-like domain | L domain-like | 2 | 2 | |
SAP domain | RING/U-box | 2 | 2 | |
PH domain-like | Immunoglobulin | 2 | 2 | |
Calponin-homology domain, CH-domain | EB1 dimerisation domain-like | 2 | 1 | |
Kix domain of CBP (creb binding protein) | RING/U-box | 2 | 2 | |
ENTH/VHS domain | SH3-domain | 2 | 2 | |
Terpenoid cyclases/Protein prenyltransferases | TIMP-like | 2 | 2 | |
Sema domain | TSP-1 type 1 repeat | 2 | 2 | |
Spermadhesin, CUB domain | Kelch motif | 2 | 2 | |
vWA-like | Complement control module/SCR domain | 2 | 2 | |
HR1 repeat | HR1 repeat | 2 | 2 | |
RUN domain-like | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 2 | 1 | |
vWA-like | SPOC domain-like | 2 | 2 | |
Ankyrin repeat | HIT/MYND zinc finger-like | 2 | 2 | |
BRCT domain | Ankyrin repeat | 2 | 2 | |
CRAL/TRIO domain | SH3-domain | 2 | 2 | |
Plakin repeat | GAS2 domain-like | 2 | 2 | |
Quinoprotein alcohol dehydrogenase-like | Protein kinase-like (PK-like) | 2 | 2 | |
P-loop containing nucleoside triphosphate hydrolases | Microbial and mitochondrial ADK, insert "zinc finger" domain | 2 | 1 | |
Concanavalin A-like lectins/glucanases | BEACH domain | 2 | 2 | |
Kringle-like | Hemopexin-like domain | 2 | 2 | |
A heparin-binding domain | CAPPD, an extracellular domain of amyloid beta A4 protein | 2 | 1 | |
Ubiquitin-like | A middle domain of Talin 1 | 2 | 2 | |
DNA breaking-rejoining enzymes | Eukaryotic DNA topoisomerase I, dispensable insert domain | 2 | 1 | |
Dimeric alpha+beta barrel | Dimeric alpha+beta barrel | 2 | 1 | |
Caspase-like | Caspase-like | 2 | 2 | |
Glucocorticoid receptor-like (DNA-binding domain) | BRCT domain | 2 | 2 | |
cAMP-binding domain-like | Protein kinase-like (PK-like) | 2 | 1 | |
(Trans)glycosidases | Invertebrate chitin-binding proteins | 2 | 1 | |
ARID-like | Chromo domain-like | 2 | 1 | |
Ribosomal protein S5 domain 2-like | GHMP Kinase, C-terminal domain | 2 | 2 | |
Eukaryotic type KH-domain (KH-domain type I) | P-loop containing nucleoside triphosphate hydrolases | 2 | 2 | |
SRCR-like | Spermadhesin, CUB domain | 2 | 2 | |
Doublecortin (DC) | Protein kinase-like (PK-like) | 2 | 2 | |
Kelch motif | EGF/Laminin | 2 | 2 | |
TAZ domain | Kix domain of CBP (creb binding protein) | 2 | 2 | |
Regulator of G-protein signaling, RGS | PX domain | 2 | 2 | |
vWA-like | Trypsin-like serine proteases | 2 | 2 | |
CO dehydrogenase ISP C-domain like | Molybdenum cofactor-binding domain | 2 | 2 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Eferin C-derminal domain-like | 2 | 1 | |
SH2 domain | Cysteine-rich domain | 2 | 2 | |
Assembly domain of cartilage oligomeric matrix protein | TSP type-3 repeat | 2 | 2 | |
Mss4-like | Mss4-like | 2 | 2 | |
Lipovitellin-phosvitin complex; beta-sheet shell regions | Lipovitellin-phosvitin complex, superhelical domain | 2 | 2 | |
FabD/lysophospholipase-like | FabD/lysophospholipase-like | 2 | 2 | |
EF-hand | SH3-domain | 2 | 2 | |
Restriction endonuclease-like | RuvA domain 2-like | 2 | 2 | |
Integrin alpha N-terminal domain | Integrin alpha N-terminal domain | 2 | 2 | |
Plexin repeat | GTPase activation domain, GAP | 2 | 2 | |
Histone-fold | Ras GEF | 2 | 2 | |
Clathrin heavy-chain terminal domain | ARM repeat | 2 | 2 | |
SH3-domain | Immunoglobulin | 2 | 2 | |
Calponin-homology domain, CH-domain | DBL homology domain (DH-domain) | 2 | 2 | |
E set domains | AMPKBI-like | 2 | 2 | |
DNA polymerase beta, N-terminal domain-like | PsbU/PolX domain-like | 2 | 2 | |
B-box zinc-binding domain | E set domains | 2 | 2 | |
Outer arm dynein light chain 1 | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FAD/NAD(P)-binding domain | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
BRCA2 helical domain | BRCA2 tower domain | 1 | 1 | |
DBL homology domain (DH-domain) | GTPase activation domain, GAP | 1 | 1 | |
Ubiquitin-like | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
N-terminal, heterodimerisation domain of RBP7 (RpoE) | Nucleic acid-binding proteins | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Signal peptide-binding domain | 1 | 1 | |
cAMP-binding domain-like | PDZ domain-like | 1 | 1 | |
Dcp2 domain-like | Nudix | 1 | 1 | |
Aldolase | Aldolase | 1 | 1 | |
Ubiquitin-like | DBL homology domain (DH-domain) | 1 | 1 | |
Rap30/74 interaction domains | Rap30/74 interaction domains | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | DNA/RNA polymerases | 1 | 1 | |
Cholecystokinin A receptor, N-domain | Family A G protein-coupled receptor-like | 1 | 1 | |
Ankyrin repeat | Heat shock protein 70kD (HSP70), C-terminal subdomain | 1 | 1 | |
EF-hand | DUSP-like | 1 | 1 | |
Rudiment single hybrid motif | PurM C-terminal domain-like | 1 | 1 | |
Dimerization cofactor of HNF-1 alpha | lambda repressor-like DNA-binding domains | 1 | 1 | |
eIF2alpha middle domain-like | eIF-2-alpha, C-terminal domain | 1 | 1 | |
TSP-1 type 1 repeat | Galactose-binding domain-like | 1 | 1 | |
Voltage-gated potassium channels | Small-conductance potassium channel | 1 | 1 | |
Hypothetical protein PH1602 | Hypothetical protein PH1602 | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | Oxidoreductase molybdopterin-binding domain | 1 | 1 | |
Acid proteases | Acid proteases | 1 | 1 | |
Lipovitellin-phosvitin complex, superhelical domain | Lipovitellin-phosvitin complex, superhelical domain | 1 | 1 | |
SH2 domain | DNase I-like | 1 | 1 | |
ACP-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
Trypsin-like serine proteases | PDZ domain-like | 1 | 1 | |
PX domain | BAR/IMD domain-like | 1 | 1 | |
Thioesterase/thiol ester dehydrase-isomerase | SCP-like | 1 | 1 | |
R1 subunit of ribonucleotide reductase, N-terminal domain | PFL-like glycyl radical enzymes | 1 | 1 | |
Oxidoreductase molybdopterin-binding domain | E set domains | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | DNA mismatch repair protein MutL | 1 | 1 | |
ARM repeat | Zn-dependent exopeptidases | 1 | 1 | |
Formiminotransferase domain of formiminotransferase-cyclodeaminase. | Methenyltetrahydrofolate cyclohydrolase-like | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Nucleotidylyl transferase | 1 | 1 | |
SAM/Pointed domain | ArfGap/RecO-like zinc finger | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | Translation proteins | 1 | 1 | |
FF domain | GTPase activation domain, GAP | 1 | 1 | |
Kringle-like | HCP-like | 1 | 1 | |
DUSP-like | DUSP-like | 1 | 1 | |
Activator of Hsp90 ATPase, Aha1 | Bet v1-like | 1 | 1 | |
FAS1 domain | C-type lectin-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Prokaryotic type KH domain (KH-domain type II) | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | Molybdenum cofactor biosynthesis proteins | 1 | 1 | |
GTPase activation domain, GAP | ARM repeat | 1 | 1 | |
PurM C-terminal domain-like | Class I glutamine amidotransferase-like | 1 | 1 | |
Protein kinase-like (PK-like) | Acyl-CoA dehydrogenase NM domain-like | 1 | 1 | |
Soluble quinoprotein glucose dehydrogenase | Soluble quinoprotein glucose dehydrogenase | 1 | 1 | |
Ribonuclease H-like | Zinc finger domain of DNA polymerase-alpha | 1 | 1 | |
Ankyrin repeat | Second domain of FERM | 1 | 1 | |
MIT domain | Calpain large subunit, middle domain (domain III) | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | Trimeric LpxA-like enzymes | 1 | 1 | |
L30e-like | alpha/beta knot | 1 | 1 | |
Apolipoprotein | Apolipoprotein A-I | 1 | 1 | |
BRCT domain | PH domain-like | 1 | 1 | |
MFS general substrate transporter | alpha/beta knot | 1 | 1 | |
TATA-box binding protein-like | DNA-glycosylase | 1 | 1 | |
USP8 N-terminal domain-like | Cysteine proteinases | 1 | 1 | |
Formyltransferase | FMT C-terminal domain-like | 1 | 1 | |
FAD/NAD(P)-binding domain | EF-hand | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | Mib/herc2 domain-like | 1 | 1 | |
ARID-like | ARM repeat | 1 | 1 | |
Transducin (alpha subunit), insertion domain | Transducin (alpha subunit), insertion domain | 1 | 1 | |
DEATH domain | HIN-2000 domain-like | 1 | 1 | |
AN1-like Zinc finger | AN1-like Zinc finger | 1 | 1 | |
Chaperone J-domain | Sec63 N-terminal domain-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Anticodon-binding domain of PheRS | 1 | 1 | |
Nucleotidyltransferase | Ubiquitin-like | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
PUA domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
TROVE domain-like | vWA-like | 1 | 1 | |
2Fe-2S ferredoxin-like | alpha-helical ferredoxin | 1 | 1 | |
"Winged helix" DNA-binding domain | GTPase activation domain, GAP | 1 | 1 | |
SAM/Pointed domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
PR-1-like | PR-1-like | 1 | 1 | |
Myosin S1 fragment, N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
4Fe-4S ferredoxins | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Hypothetical protein YjiA, C-terminal domain | 1 | 1 | |
Sema domain | Protein kinase-like (PK-like) | 1 | 1 | |
PurM C-terminal domain-like | PurM C-terminal domain-like | 1 | 1 | |
Ras GEF | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
TAFH domain-like | Histone-fold | 1 | 1 | |
PEP carboxykinase N-terminal domain | PEP carboxykinase N-terminal domain | 1 | 1 | |
CAD & PB1 domains | SH3-domain | 1 | 1 | |
WW domain | BAR/IMD domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | SOCS box-like | 1 | 1 | |
Ribosomal protein L22 | Ribosomal protein L22 | 1 | 1 | |
Zinc beta-ribbon | Cyclin-like | 1 | 1 | |
Ubiquitin-like | SH3-domain | 1 | 1 | |
Nucleotide-binding domain | 4Fe-4S ferredoxins | 1 | 1 | |
RCC1/BLIP-II | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Galactose-binding domain-like | Kelch motif | 1 | 1 | |
SET domain | WW domain | 1 | 1 | |
Kazal-type serine protease inhibitors | SRCR-like | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | Putative DNA-binding domain | 1 | 1 | |
PKD domain | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | 1 | |
N-(deoxy)ribosyltransferase-like | N-(deoxy)ribosyltransferase-like | 1 | 1 | |
Carbamate kinase-like | ALDH-like | 1 | 1 | |
UBC-like | RING/U-box | 1 | 1 | |
Kringle-like | Spermadhesin, CUB domain | 1 | 1 | |
PH domain-like | Bet v1-like | 1 | 1 | |
RNA-binding domain, RBD | Nucleotidyltransferase | 1 | 1 | |
Growth factor receptor domain | Leech antihemostatic proteins | 1 | 1 | |
Calponin-homology domain, CH-domain | PRC-barrel domain | 1 | 1 | |
Nucleic acid-binding proteins | GAD domain-like | 1 | 1 | |
Domain of the SRP/SRP receptor G-proteins | Signal peptide-binding domain | 1 | 1 | |
Mannose 6-phosphate receptor domain | Mannose 6-phosphate receptor domain | 1 | 1 | |
C-type lectin-like | Growth factor receptor domain | 1 | 1 | |
C-terminal domain of adenylylcyclase associated protein | Nucleoside diphosphate kinase, NDK | 1 | 1 | |
Ribonuclease Rh-like | Ribonuclease Rh-like | 1 | 1 | |
Tubby C-terminal domain-like | Tubby C-terminal domain-like | 1 | 1 | |
FAD-linked reductases, C-terminal domain | EF-hand | 1 | 1 | |
Bromodomain | Nuclear receptor coactivator interlocking domain | 1 | 1 | |
DBL homology domain (DH-domain) | WD40 repeat-like | 1 | 1 | |
ENTH/VHS domain | I/LWEQ domain | 1 | 1 | |
Radical SAM enzymes | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Spermadhesin, CUB domain | 1 | 1 | |
F-box domain | PH domain-like | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | HMG-box | 1 | 1 | |
PUA domain-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
F-box domain | Kelch motif | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Actin-like ATPase domain | 1 | 1 | |
Kringle-like | Fibronectin type III | 1 | 1 | |
GroEL apical domain-like | SAICAR synthase-like | 1 | 1 | |
EGF/Laminin | NHL repeat | 1 | 1 | |
Protein kinase-like (PK-like) | WD40 repeat-like | 1 | 1 | |
Nucleotidylyl transferase | C-terminal domain of ProRS | 1 | 1 | |
Inosine monophosphate dehydrogenase (IMPDH) | Inosine monophosphate dehydrogenase (IMPDH) | 1 | 1 | |
S15/NS1 RNA-binding domain | C-terminal domain of ProRS | 1 | 1 | |
RCC1/BLIP-II | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
4Fe-4S ferredoxins | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 | Elongation factor TFIIS domain 2 | 1 | 1 | |
L domain-like | DNase I-like | 1 | 1 | |
Ribonuclease H-like | SH2 domain | 1 | 1 | |
Ribonuclease PH domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
CAD & PB1 domains | C-terminal domain of DFF45/ICAD (DFF-C domain) | 1 | 1 | |
PH domain-like | Glycolipid transfer protein, GLTP | 1 | 1 | |
DAK1/DegV-like | DhaL-like | 1 | 1 | |
Growth factor receptor domain | CalX-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | 1 | 1 | |
Frizzled cysteine-rich domain | LDL receptor-like module | 1 | 1 | |
GST C-terminal domain-like | Nucleotidylyl transferase | 1 | 1 | |
PLP-dependent transferases | PK beta-barrel domain-like | 1 | 1 | |
PK beta-barrel domain-like | Phosphoenolpyruvate/pyruvate domain | 1 | 1 | |
Ribosomal protein S5 domain 2-like | DNA mismatch repair protein MutL | 1 | 1 | |
POZ domain | FYVE/PHD zinc finger | 1 | 1 | |
FnI-like domain | Leech antihemostatic proteins | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Macro domain-like | 1 | 1 | |
WD40 repeat-like | Cysteine proteinases | 1 | 1 | |
Intermediate filament protein, coiled coil region | Lamin A/C globular tail domain | 1 | 1 | |
NagB/RpiA/CoA transferase-like | RNA-binding domain, RBD | 1 | 1 | |
SWIB/MDM2 domain | eIF1-like | 1 | 1 | |
Metallo-dependent phosphatases | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
Tumor suppressor gene product Apc | ARM repeat | 1 | 1 | |
PUA domain-like | eIF1-like | 1 | 1 | |
AXH domain | HMG-box | 1 | 1 | |
Lipase/lipooxygenase domain (PLAT/LH2 domain) | Voltage-gated potassium channels | 1 | 1 | |
WW domain | Ubiquitin-like | 1 | 1 | |
FYVE/PHD zinc finger | RNI-like | 1 | 1 | |
Protein kinase-like (PK-like) | HCP-like | 1 | 1 | |
GST C-terminal domain-like | Class II aaRS and biotin synthetases | 1 | 1 | |
Midkine | Midkine | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Chaperone J-domain | 1 | 1 | |
Cysteine-rich DNA binding domain, (DM domain) | UBA-like | 1 | 1 | |
RCC1/BLIP-II | DBL homology domain (DH-domain) | 1 | 1 | |
Nucleic acid-binding proteins | SAP domain | 1 | 1 | |
DNA/RNA polymerases | Zinc finger domain of DNA polymerase-alpha | 1 | 1 | |
ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase | 1 | 1 | |
DNA-glycosylase | Nudix | 1 | 1 | |
Nucleic acid-binding proteins | SH2 domain | 1 | 1 | |
Metallo-dependent phosphatases | EF-hand | 1 | 1 | |
Isocitrate/Isopropylmalate dehydrogenase-like | Isocitrate/Isopropylmalate dehydrogenase-like | 1 | 1 | |
EGF/Laminin | Carboxypeptidase regulatory domain-like | 1 | 1 | |
FnI-like domain | CalX-like | 1 | 1 | |
beta-beta-alpha zinc fingers | Nucleotidyltransferase | 1 | 1 | |
Families 57/38 glycoside transferase middle domain | Galactose mutarotase-like | 1 | 1 | |
Ricin B-like lectins | Ricin B-like lectins | 1 | 1 | |
Succinyl-CoA synthetase domains | Citrate synthase | 1 | 1 | |
Guanido kinase N-terminal domain | Glutamine synthetase/guanido kinase | 1 | 1 | |
Spermadhesin, CUB domain | TIMP-like | 1 | 1 | |
FYVE/PHD zinc finger | Supernatant protein factor (SPF), C-terminal domain | 1 | 1 | |
vWA-like | GFP-like | 1 | 1 | |
alpha-helical ferredoxin | 4Fe-4S ferredoxins | 1 | 1 | |
Anthrax protective antigen | Cupredoxins | 1 | 1 | |
PAZ domain | RNase III domain-like | 1 | 1 | |
BRCT domain | DNA/RNA polymerases | 1 | 1 | |
Glutamine synthetase/guanido kinase | GatB/YqeY motif | 1 | 1 | |
Acyl-CoA binding protein | Ankyrin repeat | 1 | 1 | |
PreATP-grasp domain | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | LDL receptor-like module | 1 | 1 | |
SAP domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
BAR/IMD domain-like | Cysteine-rich domain | 1 | 1 | |
L domain-like | Ubiquitin-like | 1 | 1 | |
F-box domain | Pectin lyase-like | 1 | 1 | |
Eea1 homodimerisation domain | FYVE/PHD zinc finger | 1 | 1 | |
Glycoside hydrolase/deacetylase | Galactose mutarotase-like | 1 | 1 | |
BRCT domain | Lesion bypass DNA polymerase (Y-family), little finger domain | 1 | 1 | |
Cobalamin (vitamin B12)-dependent enzymes | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
CAD & PB1 domains | RING/U-box | 1 | 1 | |
L domain-like | Concanavalin A-like lectins/glucanases | 1 | 1 | |
vWA-like | C-terminal domain of Ku80 | 1 | 1 | |
NAD-binding domain of HMG-CoA reductase | Substrate-binding domain of HMG-CoA reductase | 1 | 1 | |
MAST3 pre-PK domain-like | PDZ domain-like | 1 | 1 | |
Concanavalin A-like lectins/glucanases | SRCR-like | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | Tudor/PWWP/MBT | 1 | 1 | |
NHL repeat | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Succinyl-CoA synthetase domains | 1 | 1 | |
TROVE domain-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
FYVE/PHD zinc finger | SAP domain | 1 | 1 | |
Triple coiled coil domain of C-type lectins | C-type lectin-like | 1 | 1 | |
TPR-like | Metallo-dependent phosphatases | 1 | 1 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Ankyrin repeat | 1 | 1 | |
BRCT domain | DBL homology domain (DH-domain) | 1 | 1 | |
PAH2 domain | PAH2 domain | 1 | 1 | |
PDZ domain-like | Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 1 | 1 | |
BAR/IMD domain-like | SH2 domain | 1 | 1 | |
Nucleotidylyl transferase | Alpha-L RNA-binding motif | 1 | 1 | |
Coiled-coil domain of nucleotide exchange factor GrpE | Head domain of nucleotide exchange factor GrpE | 1 | 1 | |
RING/U-box | Nuclear receptor coactivator interlocking domain | 1 | 1 | |
Nucleic acid-binding proteins | eIF2alpha middle domain-like | 1 | 1 | |
PUG domain-like | Cysteine proteinases | 1 | 1 | |
Ankyrin repeat | FYVE/PHD zinc finger | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Trypsin-like serine proteases | 1 | 1 | |
V-type ATP synthase subunit C | V-type ATP synthase subunit C | 1 | 1 | |
R3H domain | RNA-binding domain, RBD | 1 | 1 | |
TPR-like | HIT/MYND zinc finger-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | PurM C-terminal domain-like | 1 | 1 | |
RNA-binding domain, RBD | SET domain | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | Chaperone J-domain | 1 | 1 | |
FGAM synthase PurL, linker domain | PurM N-terminal domain-like | 1 | 1 | |
ARM repeat | alpha/beta-Hydrolases | 1 | 1 | |
FAD-binding/transporter-associated domain-like | Molybdenum cofactor-binding domain | 1 | 1 | |
Fe,Mn superoxide dismutase (SOD), N-terminal domain | Fe,Mn superoxide dismutase (SOD), C-terminal domain | 1 | 1 | |
Heme-dependent peroxidases | Complement control module/SCR domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | ArfGap/RecO-like zinc finger | 1 | 1 | |
Calponin-homology domain, CH-domain | WW domain | 1 | 1 | |
Saposin | Saposin | 1 | 1 | |
LCCL domain | Galactose-binding domain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | GAD domain-like | 1 | 1 | |
Somatomedin B domain | EndoU-like | 1 | 1 | |
MIT domain | Cysteine proteinases | 1 | 1 | |
DEATH domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
E set domains | Hect, E3 ligase catalytic domain | 1 | 1 | |
FAD-linked reductases, C-terminal domain | Aminomethyltransferase beta-barrel domain | 1 | 1 | |
C-type lectin-like | Voltage-gated potassium channels | 1 | 1 | |
Pseudo ankyrin repeat-like | SOCS box-like | 1 | 1 | |
2Fe-2S ferredoxin-like | Formate dehydrogenase/DMSO reductase, domains 1-3 | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase domain | 1 | 1 | |
tRNA-guanine transglycosylase | tRNA-guanine transglycosylase | 1 | 1 | |
KRAB domain (Kruppel-associated box) | Homeodomain-like | 1 | 1 | |
Tudor/PWWP/MBT | Galactose-binding domain-like | 1 | 1 | |
Homocysteine S-methyltransferase | Methionine synthase activation domain-like | 1 | 1 | |
YWTD domain | Protein kinase-like (PK-like) | 1 | 1 | |
GTPase activation domain, GAP | VPS9 domain | 1 | 1 | |
ARM repeat | Toll/Interleukin receptor TIR domain | 1 | 1 | |
Acetyl-CoA synthetase-like | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
Cytochrome c oxidase subunit II-like, transmembrane region | Cupredoxins | 1 | 1 | |
Bromodomain | HMG-box | 1 | 1 | |
Inhibitor of apoptosis (IAP) repeat | RING/U-box | 1 | 1 | |
Heme-dependent catalase-like | Heme-dependent catalase-like | 1 | 1 | |
POZ domain | Pentapeptide repeat-like | 1 | 1 | |
"Winged helix" DNA-binding domain | HRDC-like | 1 | 1 | |
p53-like transcription factors | HLH, helix-loop-helix DNA-binding domain | 1 | 1 | |
Dihydropteroate synthetase-like | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
PH domain-like | Ran binding protein zinc finger-like | 1 | 1 | |
FAD-linked reductases, C-terminal domain | Folate-binding domain | 1 | 1 | |
Galactose oxidase, central domain | Galactose oxidase, central domain | 1 | 1 | |
Nucleotide cyclase | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Calponin-homology domain, CH-domain | ARM repeat | 1 | 1 | |
PurS-like | Class I glutamine amidotransferase-like | 1 | 1 | |
L domain-like | Actin depolymerizing proteins | 1 | 1 | |
Homocysteine S-methyltransferase | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
FAD-binding/transporter-associated domain-like | CO dehydrogenase flavoprotein C-terminal domain-like | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | Fibronectin type III | 1 | 1 | |
Sm-like ribonucleoproteins | Sm-like ribonucleoproteins | 1 | 1 | |
PDZ domain-like | BAR/IMD domain-like | 1 | 1 | |
EF-hand | Dimeric alpha+beta barrel | 1 | 1 | |
Ubiquitin-like | SMAD/FHA domain | 1 | 1 | |
Calponin-homology domain, CH-domain | Ubiquitin-like | 1 | 1 | |
EF-hand | Ubiquitin-like | 1 | 1 | |
ERH-like | ERH-like | 1 | 1 | |
Prim-pol domain | Prim-pol domain | 1 | 1 | |
PDZ domain-like | PX domain | 1 | 1 | |
LDL receptor-like module | FnI-like domain | 1 | 1 | |
FYVE/PHD zinc finger | Elongation factor TFIIS domain 2 | 1 | 1 | |
(Trans)glycosidases | beta-Galactosidase/glucuronidase domain | 1 | 1 | |
YaeB-like | YaeB-like | 1 | 1 | |
L domain-like | RNI-like | 1 | 1 | |
KRAB domain (Kruppel-associated box) | Ribonuclease H-like | 1 | 1 | |
Composite domain of metallo-dependent hydrolases | Composite domain of metallo-dependent hydrolases | 1 | 1 | |
Protein kinase-like (PK-like) | L27 domain | 1 | 1 | |
Retrovirus zinc finger-like domains | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
L domain-like | Putative isomerase YbhE | 1 | 1 | |
BRCA2 helical domain | Nucleic acid-binding proteins | 1 | 1 | |
vWA-like | TSP-1 type 1 repeat | 1 | 1 | |
Class II aaRS and biotin synthetases | Translation proteins | 1 | 1 | |
HIT/MYND zinc finger-like | Tudor/PWWP/MBT | 1 | 1 | |
Immunoglobulin | Kringle-like | 1 | 1 | |
GST C-terminal domain-like | eEF-1beta-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | DHS-like NAD/FAD-binding domain | 1 | 1 | |
Methionine synthase domain | Cobalamin (vitamin B12)-binding domain | 1 | 1 | |
vWA-like | Immunoglobulin | 1 | 1 | |
2Fe-2S ferredoxin-like | CO dehydrogenase flavoprotein C-terminal domain-like | 1 | 1 | |
DBL homology domain (DH-domain) | Fibronectin type III | 1 | 1 | |
UBA-like | CCCH zinc finger | 1 | 1 | |
SAICAR synthase-like | SAICAR synthase-like | 1 | 1 | |
Cobalamin (vitamin B12)-dependent enzymes | Cobalamin (vitamin B12)-dependent enzymes | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Ribonuclease PH domain 2-like | 1 | 1 | |
ARM repeat | SAM/Pointed domain | 1 | 1 | |
Calcyclin-binding protein-like | HSP20-like chaperones | 1 | 1 | |
Histone-fold | Histone-fold | 1 | 1 | |
SMAD/FHA domain | HAD-like | 1 | 1 | |
Cysteine proteinases | Tudor/PWWP/MBT | 1 | 1 | |
DBL homology domain (DH-domain) | BAR/IMD domain-like | 1 | 1 | |
Carboxypeptidase regulatory domain-like | Carboxypeptidase regulatory domain-like | 1 | 1 | |
DNA repair protein MutS, domain III | DNA repair protein MutS, domain III | 1 | 1 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Nucleotidylyl transferase | 1 | 1 | |
Domain of poly(ADP-ribose) polymerase | vWA-like | 1 | 1 | |
Flavoproteins | Flavoproteins | 1 | 1 | |
Rhodanese/Cell cycle control phosphatase | Cysteine proteinases | 1 | 1 | |
Calponin-homology domain, CH-domain | SH2 domain | 1 | 1 | |
Formin homology 2 domain (FH2 domain) | Cysteine proteinases | 1 | 1 | |
SEA domain | Spermadhesin, CUB domain | 1 | 1 | |
RING/U-box | DUSP-like | 1 | 1 | |
LDL receptor-like module | Complement control module/SCR domain | 1 | 1 | |
BRCT domain | Uteroglobin-like | 1 | 1 | |
ArfGap/RecO-like zinc finger | Ubiquitin-like | 1 | 1 | |
Nucleic acid-binding proteins | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
PLC-like phosphodiesterases | Ubiquitin-like | 1 | 1 | |
RING/U-box | E set domains | 1 | 1 | |
GYF domain | ARM repeat | 1 | 1 | |
PreATP-grasp domain | Formyltransferase | 1 | 1 | |
Macro domain-like | Zn-dependent exopeptidases | 1 | 1 | |
UBA-like | Protein kinase-like (PK-like) | 1 | 1 | |
FYVE/PHD zinc finger | PUA domain-like | 1 | 1 | |
E set domains | Glycosyl hydrolase domain | 1 | 1 | |
Galactose-binding domain-like | TIMP-like | 1 | 1 | |
Single hybrid motif | Single hybrid motif | 1 | 1 | |
CAD & PB1 domains | Cysteine-rich domain | 1 | 1 | |
Proteasome activator | Proteasome activator | 1 | 1 | |
PABC (PABP) domain | Hect, E3 ligase catalytic domain | 1 | 1 | |
EPT/RTPC-like | EPT/RTPC-like | 1 | 1 | |
PreATP-grasp domain | Methylglyoxal synthase-like | 1 | 1 | |
Kazal-type serine protease inhibitors | Trypsin-like serine proteases | 1 | 1 | |
RNI-like | Toll/Interleukin receptor TIR domain | 1 | 1 | |
Ankyrin repeat | Oxysterol-binding protein-like | 1 | 1 | |
DNA repair protein MutS, domain II | DNA repair protein MutS, domain III | 1 | 1 | |
p53 tetramerization domain | SAM/Pointed domain | 1 | 1 | |
CAD & PB1 domains | PDZ domain-like | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Class I glutamine amidotransferase-like | 1 | 1 | |
Kix domain of CBP (creb binding protein) | Nuclear receptor coactivator interlocking domain | 1 | 1 | |
Immunoglobulin | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Actin-crosslinking proteins | Actin-crosslinking proteins | 1 | 1 | |
Class I glutamine amidotransferase-like | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
CRAL/TRIO domain | Fibronectin type III | 1 | 1 | |
PDZ domain-like | Ras GEF | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
USP8 N-terminal domain-like | JAB1/MPN domain | 1 | 1 | |
AraD/HMP-PK domain-like | AraD/HMP-PK domain-like | 1 | 1 | |
DUSP-like | Ubiquitin-like | 1 | 1 | |
XRCC4, N-terminal domain | XRCC4, C-terminal oligomerization domain | 1 | 1 | |
gamma-Crystallin-like | Ricin B-like lectins | 1 | 1 | |
RCC1/BLIP-II | Mib/herc2 domain-like | 1 | 1 | |
C2 domain (Calcium/lipid-binding domain, CaLB) | Chaperone J-domain | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Cysteine proteinases | 1 | 1 | |
L domain-like | PP2C-like | 1 | 1 | |
Ran binding protein zinc finger-like | RING/U-box | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | Nucleic acid-binding proteins | 1 | 1 | |
SNARE-like | Domain of the SRP/SRP receptor G-proteins | 1 | 1 | |
PAH2 domain | Homeodomain-like | 1 | 1 | |
Spectrin repeat | WW domain | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Carbamoyl phosphate synthetase, large subunit connection domain | 1 | 1 | |
Ras GEF | PLC-like phosphodiesterases | 1 | 1 | |
DEATH domain | WD40 repeat-like | 1 | 1 | |
RCC1/BLIP-II | WD40 repeat-like | 1 | 1 | |
Ankyrin repeat | Galactose-binding domain-like | 1 | 1 | |
Ankyrin repeat | L domain-like | 1 | 1 | |
Eukaryotic type KH-domain (KH-domain type I) | SAM/Pointed domain | 1 | 1 | |
p53-like transcription factors | Ankyrin repeat | 1 | 1 | |
L domain-like | Polo-box domain | 1 | 1 | |
DNase I-like | SAM/Pointed domain | 1 | 1 | |
Acyl-CoA binding protein | Supernatant protein factor (SPF), C-terminal domain | 1 | 1 | |
Cullin homology domain | Cullin homology domain | 1 | 1 | |
Somatomedin B domain | Hemopexin-like domain | 1 | 1 | |
Methionyl-tRNA synthetase (MetRS), Zn-domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
RNA-binding domain, RBD | PAP/OAS1 substrate-binding domain | 1 | 1 | |
GDNF receptor-like | GDNF receptor-like | 1 | 1 | |
BRCT domain | vWA-like | 1 | 1 | |
HSP20-like chaperones | Riboflavin synthase domain-like | 1 | 1 | |
Growth factor receptor domain | Complement control module/SCR domain | 1 | 1 | |
Glycolipid transfer protein, GLTP | Glycolipid transfer protein, GLTP | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Protein kinase-like (PK-like) | 1 | 1 | |
Galactose-binding domain-like | BRCT domain | 1 | 1 | |
Carboxypeptidase regulatory domain-like | NHL repeat | 1 | 1 | |
UBC-like | LDH C-terminal domain-like | 1 | 1 | |
SH2 domain | UBA-like | 1 | 1 | |
TPR-like | "Winged helix" DNA-binding domain | 1 | 1 | |
C-type lectin-like | Lipase/lipooxygenase domain (PLAT/LH2 domain) | 1 | 1 | |
EF-hand | Immunoglobulin | 1 | 1 | |
FAD-binding/transporter-associated domain-like | FAD-linked oxidases, C-terminal domain | 1 | 1 | |
Nucleotidylyl transferase | Nucleotidylyl transferase | 1 | 1 | |
Arginyl-tRNA synthetase (ArgRS), N-terminal 'additional' domain | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases | 1 | 1 | |
Rudiment single hybrid motif | Formyltransferase | 1 | 1 | |
DBL homology domain (DH-domain) | VPS9 domain | 1 | 1 | |
Thyroglobulin type-1 domain | YWTD domain | 1 | 1 | |
GST C-terminal domain-like | S15/NS1 RNA-binding domain | 1 | 1 | |
E set domains | DEATH domain | 1 | 1 | |
Protein kinase-like (PK-like) | Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 1 | 1 | |
PYP-like sensor domain (PAS domain) | Positive stranded ssRNA viruses | 1 | 1 | |
HAD-like | Acyl-CoA dehydrogenase NM domain-like | 1 | 1 | |
Fe-only hydrogenase | Fe-only hydrogenase smaller subunit | 1 | 1 | |
UBC-like | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
Ubiquitin-like | HAD-like | 1 | 1 | |
PurM C-terminal domain-like | Formyltransferase | 1 | 1 | |
TPR-like | beta-beta-alpha zinc fingers | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Putative methyltransferase TM0872, insert domain | 1 | 1 | |
Thyroglobulin type-1 domain | alpha/beta-Hydrolases | 1 | 1 | |
MAST3 pre-PK domain-like | Protein kinase-like (PK-like) | 1 | 1 | |
Ubiquitin-like | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | Nucleic acid-binding proteins | 1 | 1 | |
GST C-terminal domain-like | Ribosomal protein L25-like | 1 | 1 | |
Homeodomain-like | JAB1/MPN domain | 1 | 1 | |
Aldolase | AFP III-like domain | 1 | 1 | |
HSP20-like chaperones | TPR-like | 1 | 1 | |
ClpS-like | "Winged helix" DNA-binding domain | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Methylglyoxal synthase-like | 1 | 1 | |
PK beta-barrel domain-like | PK C-terminal domain-like | 1 | 1 | |
UBA-like | Tudor/PWWP/MBT | 1 | 1 | |
PH domain-like | Cyclophilin-like | 1 | 1 | |
PreATP-grasp domain | PurM C-terminal domain-like | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase activation domain-like | 1 | 1 | |
SNARE-like | SNARE fusion complex | 1 | 1 | |
UBA-like | Thioredoxin-like | 1 | 1 | |
Chelatase | Chelatase | 1 | 1 | |
USP8 N-terminal domain-like | Rhodanese/Cell cycle control phosphatase | 1 | 1 | |
EGF/Laminin | TIMP-like | 1 | 1 | |
PH domain-like | Fibronectin type III | 1 | 1 | |
CRAL/TRIO domain | CRAL/TRIO domain | 1 | 1 | |
XPC-binding domain | UBA-like | 1 | 1 | |
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | Protein kinase-like (PK-like) | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 | |
PurM N-terminal domain-like | PurM N-terminal domain-like | 1 | 1 | |
Kringle-like | SRCR-like | 1 | 1 | |
ADC-like | Cdc48 domain 2-like | 1 | 1 | |
BAR/IMD domain-like | Protein kinase-like (PK-like) | 1 | 1 | |
Cysteine-rich domain | SAM/Pointed domain | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | WGR domain-like | 1 | 1 | |
Actin depolymerizing proteins | VHP, Villin headpiece domain | 1 | 1 | |
HLH, helix-loop-helix DNA-binding domain | Positive stranded ssRNA viruses | 1 | 1 | |
Phospholipase A2, PLA2 | Phospholipase A2, PLA2 | 1 | 1 | |
Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RGC domain-like | 1 | 1 | |
PDZ domain-like | GTPase activation domain, GAP | 1 | 1 | |
DNA repair protein MutS, domain II | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Hypothetical protein SAV1430 | Fe-S cluster assembly (FSCA) domain-like | 1 | 1 | |
2Fe-2S ferredoxin-like | Molybdenum cofactor-binding domain | 1 | 1 | |
HD-domain/PDEase-like | HD-domain/PDEase-like | 1 | 1 | |
Kazal-type serine protease inhibitors | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 | |
SMAD/FHA domain | HIT-like | 1 | 1 | |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | Translational machinery components | 1 | 1 | |
RING/U-box | NRDP1 C-terminal domain-like | 1 | 1 | |
TAZ domain | Nuclear receptor coactivator interlocking domain | 1 | 1 | |
SEA domain | Immunoglobulin | 1 | 1 | |
HMA, heavy metal-associated domain | Metal cation-transporting ATPase, ATP-binding domain N | 1 | 1 | |
Ribonuclease H-like | "Winged helix" DNA-binding domain | 1 | 1 | |
WD40 repeat-like | SH3-domain | 1 | 1 | |
Thiamin pyrophosphokinase, catalytic domain | Thiamin pyrophosphokinase, substrate-binding domain | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | Methylglyoxal synthase-like | 1 | 1 | |
MIR domain | ARM repeat | 1 | 1 | |
Taf5 N-terminal domain-like | WD40 repeat-like | 1 | 1 | |
DBL homology domain (DH-domain) | SH2 domain | 1 | 1 | |
Frizzled cysteine-rich domain | Trypsin-like serine proteases | 1 | 1 | |
SPOC domain-like | C-terminal domain of Ku80 | 1 | 1 | |
PDZ domain-like | Cysteine-rich domain | 1 | 1 | |
Ubiquitin-like | Ankyrin repeat | 1 | 1 | |
Clavaminate synthase-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
RUN domain-like | Ypt/Rab-GAP domain of gyp1p | 1 | 1 | |
Translation proteins | Translation proteins | 1 | 1 | |
HAD-like | BRCT domain | 1 | 1 | |
Transcription factor IIA (TFIIA), alpha-helical domain | Transcription factor IIA (TFIIA), beta-barrel domain | 1 | 1 | |
UBA-like | Phosphoglycerate mutase-like | 1 | 1 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
EF-hand | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 | |
GST C-terminal domain-like | Class II aaRS ABD-related | 1 | 1 | |
TPR-like | PH domain-like | 1 | 1 | |
Chromo domain-like | Ankyrin repeat | 1 | 1 | |
p53-like transcription factors | p53 tetramerization domain | 1 | 1 | |
Leech antihemostatic proteins | Leech antihemostatic proteins | 1 | 1 | |
HAD-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
TPR-like | SET domain | 1 | 1 | |
BB1717-like | BB1717-like | 1 | 1 | |
Galactose-binding domain-like | Cullin homology domain | 1 | 1 | |
NagB/RpiA/CoA transferase-like | D-ribose-5-phosphate isomerase (RpiA), lid domain | 1 | 1 | |
FAD-linked reductases, C-terminal domain | 4Fe-4S ferredoxins | 1 | 1 | |
Frizzled cysteine-rich domain | Frizzled cysteine-rich domain | 1 | 1 | |
RNA-binding domain, RBD | Retrovirus zinc finger-like domains | 1 | 1 | |
E set domains | Cupredoxins | 1 | 1 | |
Methylglyoxal synthase-like | Cytidine deaminase-like | 1 | 1 | |
Regulator of G-protein signaling, RGS | Ubiquitin-like | 1 | 1 | |
Immunoglobulin | Heme-dependent peroxidases | 1 | 1 | |
Kazal-type serine protease inhibitors | LDL receptor-like module | 1 | 1 | |
Telomeric repeat binding factor (TRF) dimerisation domain | Telomeric repeat binding factor (TRF) dimerisation domain | 1 | 1 | |
Translation initiation factor IF3, N-terminal domain | Translation initiation factor IF3, C-terminal domain | 1 | 1 | |
MIT domain | Protein kinase-like (PK-like) | 1 | 1 | |
Acyl-CoA binding protein | ClpP/crotonase | 1 | 1 | |
THUMP domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
FnI-like domain | Trypsin-like serine proteases | 1 | 1 | |
FKBP-like | TPR-like | 1 | 1 | |
EF-hand | Myosin rod fragments | 1 | 1 | |
ADP-ribosylation | vWA-like | 1 | 1 | |
RNA-binding domain, RBD | DPP6 N-terminal domain-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 | 1 | 1 | |
BRCT domain | WGR domain-like | 1 | 1 | |
Ribosomal protein L25-like | S15/NS1 RNA-binding domain | 1 | 1 | |
Kringle-like | Protein kinase-like (PK-like) | 1 | 1 | |
Glycosyl hydrolase domain | Glycosyl hydrolase domain | 1 | 1 | |
CRAL/TRIO domain | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
SH3-domain | SAM/Pointed domain | 1 | 1 | |
SMAD/FHA domain | PDZ domain-like | 1 | 1 | |
Succinyl-CoA synthetase domains | Succinyl-CoA synthetase domains | 1 | 1 | |
Ribosomal protein L25-like | Class II aaRS and biotin synthetases | 1 | 1 | |
Kelch motif | Fibronectin type III | 1 | 1 | |
RING/U-box | Formin homology 2 domain (FH2 domain) | 1 | 1 | |
Flavoproteins | Radical SAM enzymes | 1 | 1 | |
R3H domain | Ankyrin repeat | 1 | 1 | |
PAZ domain | dsRNA-binding domain-like | 1 | 1 | |
R3H domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Ubiquitin-like | TPR-like | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | ADP-ribosylation | 1 | 1 | |
HAD-like | Protein kinase-like (PK-like) | 1 | 1 | |
Ribosomal protein L7/12, oligomerisation (N-terminal) domain | ClpS-like | 1 | 1 | |
Rap/Ran-GAP | Rap/Ran-GAP | 1 | 1 | |
Cdc48 domain 2-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
FYVE/PHD zinc finger | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
DNA-binding domain | Tudor/PWWP/MBT | 1 | 1 | |
Retrovirus zinc finger-like domains | RING/U-box | 1 | 1 | |
PurS-like | PurM C-terminal domain-like | 1 | 1 | |
Trefoil | Trefoil | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | Hect, E3 ligase catalytic domain | 1 | 1 | |
Chaperone J-domain | E set domains | 1 | 1 | |
Class I glutamine amidotransferase-like | PreATP-grasp domain | 1 | 1 | |
Carboxypeptidase regulatory domain-like | Immunoglobulin | 1 | 1 | |
PH domain-like | RING/U-box | 1 | 1 | |
Galactose-binding domain-like | RING/U-box | 1 | 1 | |
Acetyl-CoA synthetase-like | ACP-like | 1 | 1 | |
Ankyrin repeat | Nudix | 1 | 1 | |
(Trans)glycosidases | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
CalX-like | C-type lectin-like | 1 | 1 | |
TROVE domain-like | TROVE domain-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Glucocorticoid receptor-like (DNA-binding domain) | 1 | 1 | |
FYVE/PHD zinc finger | Hect, E3 ligase catalytic domain | 1 | 1 | |
Ribosomal protein S5 domain 2-like | HMG-box | 1 | 1 | |
Prokaryotic type KH domain (KH-domain type II) | Ribosomal protein S3 C-terminal domain | 1 | 1 | |
TPR-like | RNA-binding domain, RBD | 1 | 1 | |
PurS-like | FGAM synthase PurL, linker domain | 1 | 1 | |
Cysteine proteinases | Ribonuclease H-like | 1 | 1 | |
UBC-like | Class II aaRS and biotin synthetases | 1 | 1 | |
SH3-domain | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Protein kinase-like (PK-like) | Rhodanese/Cell cycle control phosphatase | 1 | 1 | |
MFS general substrate transporter | Pentapeptide repeat-like | 1 | 1 | |
PH domain-like | BSD domain-like | 1 | 1 | |
Lissencephaly-1 protein (Lis-1, PAF-AH alpha) N-terminal domain | WD40 repeat-like | 1 | 1 | |
Dom34/Pelota N-terminal domain-like | L30e-like | 1 | 1 | |
FAD/NAD(P)-binding domain | Aminomethyltransferase beta-barrel domain | 1 | 1 | |
EF-hand | Rhomboid-like | 1 | 1 | |
Nucleotide-binding domain | Nucleotide-binding domain | 1 | 1 | |
SAP domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
PX domain | Phospholipase D/nuclease | 1 | 1 | |
Subtilisin-like | Growth factor receptor domain | 1 | 1 | |
BEACH domain | FYVE/PHD zinc finger | 1 | 1 | |
Lipovitellin-phosvitin complex; beta-sheet shell regions | Lipovitellin-phosvitin complex; beta-sheet shell regions | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | Domain of poly(ADP-ribose) polymerase | 1 | 1 | |
Ribosomal protein L25-like | C-terminal domain of ProRS | 1 | 1 | |
Nucleic acid-binding proteins | Retrovirus zinc finger-like domains | 1 | 1 | |
PHM/PNGase F | Calcium-dependent phosphotriesterase | 1 | 1 | |
mRNA decapping enzyme DcpS N-terminal domain | HIT-like | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain | 1 | 1 | |
Immunoglobulin | Caspase-like | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 | |
PX domain | MIT domain | 1 | 1 | |
TRAF domain-like | NRDP1 C-terminal domain-like | 1 | 1 | |
LDL receptor-like module | C-type lectin-like | 1 | 1 | |
NHL repeat | NHL repeat | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Formyltransferase | 1 | 1 | |
PurM N-terminal domain-like | PurM C-terminal domain-like | 1 | 1 | |
alpha-helical ferredoxin | Nucleotide-binding domain | 1 | 1 | |
PUA domain-like | Ribosomal protein S5 domain 2-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Citrate synthase | 1 | 1 | |
"Winged helix" DNA-binding domain | GroEL-intermediate domain like | 1 | 1 | |
Second domain of Mu2 adaptin subunit (ap50) of ap2 adaptor | Transcription factor IIA (TFIIA), beta-barrel domain | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Thioesterase/thiol ester dehydrase-isomerase | 1 | 1 | |
Acyl-CoA N-acyltransferases (Nat) | Bromodomain | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | beta-beta-alpha zinc fingers | 1 | 1 | |
RUN domain-like | Supernatant protein factor (SPF), C-terminal domain | 1 | 1 | |
Ankyrin repeat | SET domain | 1 | 1 | |
Nucleic acid-binding proteins | TPR-like | 1 | 1 | |
FMN-linked oxidoreductases | 4Fe-4S ferredoxins | 1 | 1 | |
F-box domain | DBL homology domain (DH-domain) | 1 | 1 | |
Homocysteine S-methyltransferase | Dihydropteroate synthetase-like | 1 | 1 | |
PX domain | Retrovirus zinc finger-like domains | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain III | 1 | 1 | |
YccV-like | ApaG-like | 1 | 1 | |
GYF domain | Chaperone J-domain | 1 | 1 | |
RUN domain-like | SH3-domain | 1 | 1 | |
FMN-linked oxidoreductases | dsRNA-binding domain-like | 1 | 1 | |
Ubiquitin-like | SAM/Pointed domain | 1 | 1 | |
Aminoacid dehydrogenase-like, N-terminal domain | Aminoacid dehydrogenase-like, N-terminal domain | 1 | 1 | |
Dipeptidyl peptidase I (cathepsin C), exclusion domain | Cysteine proteinases | 1 | 1 | |
Methionine synthase domain | Methionine synthase activation domain-like | 1 | 1 | |
Translation initiation factor 2 beta, aIF2beta, N-terminal domain | Zinc-binding domain of translation initiation factor 2 beta | 1 | 1 | |
Undecaprenyl diphosphate synthase | Undecaprenyl diphosphate synthase | 1 | 1 | |
UBC-like | UBA-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Restriction endonuclease-like | 1 | 1 | |
B-box zinc-binding domain | B-box zinc-binding domain | 1 | 1 | |
NAD kinase/diacylglycerol kinase-like | Ankyrin repeat | 1 | 1 | |
Cupredoxins | Pectin lyase-like | 1 | 1 | |
EGF/Laminin | TNF-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Second domain of FERM | 1 | 1 | |
N-terminal domain of cbl (N-cbl) | UBA-like | 1 | 1 | |
Carbohydrate phosphatase | Carbohydrate phosphatase | 1 | 1 | |
beta-beta-alpha zinc fingers | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Class I glutamine amidotransferase-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
SIS domain | SIS domain | 1 | 1 | |
Ubiquitin-like | NAD kinase/diacylglycerol kinase-like | 1 | 1 | |
dsRNA-binding domain-like | Protein kinase-like (PK-like) | 1 | 1 | |
GMP synthetase C-terminal dimerisation domain | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
NAD kinase/diacylglycerol kinase-like | SAM/Pointed domain | 1 | 1 | |
Nucleic acid-binding proteins | "Winged helix" DNA-binding domain | 1 | 1 | |
SH2 domain | VPS9 domain | 1 | 1 | |
ApaG-like | ApaG-like | 1 | 1 | |
TRAF domain-like | PDZ domain-like | 1 | 1 | |
RING/U-box | Cyclophilin-like | 1 | 1 | |
2Fe-2S ferredoxin-like | 4Fe-4S ferredoxins | 1 | 1 | |
Protein kinase-like (PK-like) | Class II aaRS and biotin synthetases | 1 | 1 | |
FYVE/PHD zinc finger | HMG-box | 1 | 1 | |
RCC1/BLIP-II | VPS9 domain | 1 | 1 | |
Tudor/PWWP/MBT | DNA repair protein MutS, domain III | 1 | 1 | |
Protein kinase-like (PK-like) | RNA-binding domain, RBD | 1 | 1 | |
TSP-1 type 1 repeat | Carboxypeptidase regulatory domain-like | 1 | 1 | |
P-domain of calnexin/calreticulin | P-domain of calnexin/calreticulin | 1 | 1 | |
Immunoglobulin | Snake toxin-like | 1 | 1 | |
PH domain-like | Tricorn protease domain 2 | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Cysteine-rich domain | 1 | 1 | |
HIT-like | HIT-like | 1 | 1 | |
UBC-like | Protein kinase-like (PK-like) | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | SMR domain-like | 1 | 1 | |
TPR-like | Ran binding protein zinc finger-like | 1 | 1 | |
DBL homology domain (DH-domain) | Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | 1 | 1 | |
SPOC domain-like | SAP domain | 1 | 1 | |
EF-hand | FnI-like domain | 1 | 1 | |
LEM domain | Ankyrin repeat | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Hect, E3 ligase catalytic domain | 1 | 1 | |
Ubiquitin-like | FAT domain of focal adhesion kinase | 1 | 1 | |
TolB, C-terminal domain | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
Phosphoenolpyruvate/pyruvate domain | PK C-terminal domain-like | 1 | 1 | |
beta-beta-alpha zinc fingers | PAP/OAS1 substrate-binding domain | 1 | 1 | |
Class II aaRS and biotin synthetases | C-terminal domain of ProRS | 1 | 1 | |
MHC antigen-recognition domain | MHC antigen-recognition domain | 1 | 1 | |
Aminoacid dehydrogenase-like, N-terminal domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
E set domains | Protein kinase-like (PK-like) | 1 | 1 | |
Tudor/PWWP/MBT | CCHHC domain | 1 | 1 | |
SAP domain | SAP domain | 1 | 1 | |
Retrovirus capsid dimerization domain-like | Ribonuclease H-like | 1 | 1 | |
Tropomyosin | Smc hinge domain | 1 | 1 | |
NHL repeat | Calcium-dependent phosphotriesterase | 1 | 1 | |
p53-like transcription factors | SAM/Pointed domain | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | VPS9 domain | 1 | 1 | |
N-terminal coiled coil domain from apc | Tumor suppressor gene product Apc | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | Galactose-binding domain-like | 1 | 1 | |
Chaperone J-domain | Homeodomain-like | 1 | 1 | |
VPS9 domain | Ankyrin repeat | 1 | 1 | |
IP3 receptor type 1 binding core, domain 2 | EF-hand | 1 | 1 | |
N-terminal coiled coil domain from apc | ARM repeat | 1 | 1 | |
Plexin repeat | TSP-1 type 1 repeat | 1 | 1 | |
Ankyrin repeat | ARM repeat | 1 | 1 | |
Nitric oxide (NO) synthase oxygenase domain | Flavoproteins | 1 | 1 | |
Thioredoxin-like | FAD/NAD-linked reductases, dimerisation (C-terminal) domain | 1 | 1 | |
Class I glutamine amidotransferase-like | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
Endosomal sorting complex assembly domain | VPS28 C-terminal domain-like | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | SIS domain | 1 | 1 | |
Inhibitor of apoptosis (IAP) repeat | UBC-like | 1 | 1 | |
NSFL1 (p97 ATPase) cofactor p47, SEP domain | Ubiquitin-like | 1 | 1 | |
Second domain of FERM | SH2 domain | 1 | 1 | |
Voltage-gated potassium channels | EF-hand | 1 | 1 | |
IP3 receptor type 1 binding core, domain 2 | ARM repeat | 1 | 1 | |
cAMP-binding domain-like | "Winged helix" DNA-binding domain | 1 | 1 | |
BRCT domain | PsbU/PolX domain-like | 1 | 1 | |
PRTase-like | Ribulose-phoshate binding barrel | 1 | 1 | |
SAP domain | RNA-binding domain, RBD | 1 | 1 | |
Elongation factor TFIIS domain 2 | Zinc beta-ribbon | 1 | 1 | |
Nucleic acid-binding proteins | eIF-2-alpha, C-terminal domain | 1 | 1 | |
HIT/MYND zinc finger-like | SET domain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Ran binding protein zinc finger-like | 1 | 1 | |
FAD/NAD(P)-binding domain | Succinate dehydrogenase/fumarate reductase flavoprotein, catalytic domain | 1 | 1 | |
Apolipoprotein | Apolipoprotein | 1 | 1 | |
alpha-helical ferredoxin | FMN-linked oxidoreductases | 1 | 1 | |
BRK domain-like | Bromodomain | 1 | 1 | |
Macro domain-like | WWE domain | 1 | 1 | |
Class I glutamine amidotransferase-like | Methylglyoxal synthase-like | 1 | 1 | |
PH domain-like | Tropomyosin | 1 | 1 | |
Ribonuclease H-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Cytochrome b5-like heme/steroid binding domain | E set domains | 1 | 1 | |
ARM repeat | Chaperone J-domain | 1 | 1 | |
DNase I-like | RNA-binding domain, RBD | 1 | 1 | |
Immunoglobulin | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 | |
WD40 repeat-like | TPR-like | 1 | 1 | |
Ribosomal L27 protein-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
PAP/OAS1 substrate-binding domain | Ubiquitin-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | PAZ domain | 1 | 1 | |
FGAM synthase PurL, linker domain | PurM C-terminal domain-like | 1 | 1 | |
Glycoside hydrolase/deacetylase | Families 57/38 glycoside transferase middle domain | 1 | 1 | |
DNA-binding domain | SET domain | 1 | 1 | |
"Winged helix" DNA-binding domain | occludin/ELL-like | 1 | 1 | |
RING/U-box | R3H domain | 1 | 1 | |
ARM repeat | Cysteine proteinases | 1 | 1 | |
Thioredoxin-like | FAD-dependent thiol oxidase | 1 | 1 | |
HR1 repeat | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | HIT/MYND zinc finger-like | 1 | 1 | |
Voltage-gated potassium channels | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
Zinc hairpin stack | RING/U-box | 1 | 1 | |
WD40 repeat-like | Hect, E3 ligase catalytic domain | 1 | 1 | |
Class I glutamine amidotransferase-like | Glutathione synthetase ATP-binding domain-like | 1 | 1 | |
S13-like H2TH domain | Ran binding protein zinc finger-like | 1 | 1 | |
FnI-like domain | TSP type-3 repeat | 1 | 1 | |
FGAM synthase PurL, linker domain | Class I glutamine amidotransferase-like | 1 | 1 | |
Ribosomal L27 protein-like | Nucleic acid-binding proteins | 1 | 1 | |
Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | Interferon-induced guanylate-binding protein 1 (GBP1), C-terminal domain | 1 | 1 | |
Concanavalin A-like lectins/glucanases | C-type lectin-like | 1 | 1 | |
Thioredoxin-like | Galactose-binding domain-like | 1 | 1 | |
Ankyrin repeat | EF-hand | 1 | 1 | |
ARID-like | "Winged helix" DNA-binding domain | 1 | 1 | |
Putative anticodon-binding domain of alanyl-tRNA synthetase (AlaRS) | ThrRS/AlaRS common domain | 1 | 1 | |
SNARE-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
CRAL/TRIO N-terminal domain | PapD-like | 1 | 1 | |
SH3-domain | Fibronectin type III | 1 | 1 | |
Ankyrin repeat | Cap-Gly domain | 1 | 1 | |
Leukotriene A4 hydrolase N-terminal domain | ARM repeat | 1 | 1 | |
beta-Galactosidase/glucuronidase domain | beta-Galactosidase/glucuronidase domain | 1 | 1 | |
RING/U-box | PDZ domain-like | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Type II DNA topoisomerase | 1 | 1 | |
EPT/RTPC-like | RNA 3'-terminal phosphate cyclase, RPTC, insert domain | 1 | 1 | |
Putative DNA-binding domain | Putative DNA-binding domain | 1 | 1 | |
Staphylococcal nuclease | Staphylococcal nuclease | 1 | 1 | |
PEP carboxykinase-like | PEP carboxykinase-like | 1 | 1 | |
Seven-hairpin glycosidases | PA domain | 1 | 1 | |
UBA-like | SH3-domain | 1 | 1 | |
Voltage-gated potassium channels | C2 domain (Calcium/lipid-binding domain, CaLB) | 1 | 1 | |
FYVE/PHD zinc finger | PDZ domain-like | 1 | 1 | |
TROVE domain-like | WD40 repeat-like | 1 | 1 | |
GST C-terminal domain-like | C-terminal domain of ProRS | 1 | 1 | |
WD40 repeat-like | Ribonuclease H-like | 1 | 1 | |
Ran binding protein zinc finger-like | Cyclophilin-like | 1 | 1 | |
DNase I-like | DNase I-like | 1 | 1 | |
Oligoxyloglucan reducing end-specific cellobiohydrolase | YWTD domain | 1 | 1 | |
Arp2/3 complex subunits | Arp2/3 complex subunits | 1 | 1 | |
RuvA domain 2-like | SH2 domain | 1 | 1 | |
NHL repeat | 3-carboxy-cis,cis-mucoante lactonizing enzyme | 1 | 1 | |
LDL receptor-like module | Fibronectin type III | 1 | 1 | |
SMAD/FHA domain | BRCT domain | 1 | 1 | |
Thioredoxin-like | FAD/NAD(P)-binding domain | 1 | 1 | |
L domain-like | WD40 repeat-like | 1 | 1 | |
Transmembrane di-heme cytochromes | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) | 1 | 1 | |
Protein prenylyltransferase | Protein prenylyltransferase | 1 | 1 | |
WD40 repeat-like | Cyclophilin-like | 1 | 1 | |
FAH | FAH | 1 | 1 | |
Fumarylacetoacetate hydrolase, FAH, N-terminal domain | FAH | 1 | 1 | |
FKBP-like | EF-hand | 1 | 1 | |
HMG-box | SET domain | 1 | 1 | |
FabD/lysophospholipase-like | Probable ACP-binding domain of malonyl-CoA ACP transacylase | 1 | 1 | |
CalX-like | Concanavalin A-like lectins/glucanases | 1 | 1 | |
UBA-like | SMR domain-like | 1 | 1 | |
dsRNA-binding domain-like | R3H domain | 1 | 1 | |
6-phosphogluconate dehydrogenase C-terminal domain-like | UDP-glucose/GDP-mannose dehydrogenase C-terminal domain | 1 | 1 | |
Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase | 1 | 1 | |
SMI1/KNR4-like | ApaG-like | 1 | 1 | |
Carbamoyl phosphate synthetase, large subunit connection domain | Methylglyoxal synthase-like | 1 | 1 | |
CHY zinc finger-like | Zinc hairpin stack | 1 | 1 | |
Staphylococcal nuclease | Protein kinase-like (PK-like) | 1 | 1 | |
DEATH domain | B-box zinc-binding domain | 1 | 1 | |
GroEL-intermediate domain like | SAICAR synthase-like | 1 | 1 | |
PreATP-grasp domain | PreATP-grasp domain | 1 | 1 | |
Ubiquitin-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Nitric oxide (NO) synthase oxygenase domain | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
Cobalamin (vitamin B12)-binding domain | Methionine synthase activation domain-like | 1 | 1 | |
N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 | L30e-like | 1 | 1 | |
RCC1/BLIP-II | Cytochrome b5-like heme/steroid binding domain | 1 | 1 | |
SEA domain | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Immunoglobulin | FnI-like domain | 1 | 1 | |
Formiminotransferase domain of formiminotransferase-cyclodeaminase. | Formiminotransferase domain of formiminotransferase-cyclodeaminase. | 1 | 1 | |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | CBS-domain pair | 1 | 1 | |
Glutamine synthetase/guanido kinase | Glutamine synthetase/guanido kinase | 1 | 1 | |
Wiscott-Aldrich syndrome protein, WASP, C-terminal domain | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain | 1 | 1 | |
EGF/Laminin | EF-hand | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
DEK C-terminal domain | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | MoeA C-terminal domain-like | 1 | 1 | |
Formyltransferase | ALDH-like | 1 | 1 | |
Dihydropteroate synthetase-like | Methionine synthase domain | 1 | 1 | |
RNA-binding domain, RBD | Tudor/PWWP/MBT | 1 | 1 | |
Tropomyosin | Eferin C-derminal domain-like | 1 | 1 | |
S-adenosyl-L-methionine-dependent methyltransferases | Metalloproteases ("zincins"), catalytic domain | 1 | 1 | |
Second domain of FERM | Second domain of FERM | 1 | 1 | |
WD40 repeat-like | HMG-box | 1 | 1 | |
Tudor/PWWP/MBT | Protein kinase-like (PK-like) | 1 | 1 | |
Lipocalins | BPTI-like | 1 | 1 | |
CHY zinc finger-like | RING/U-box | 1 | 1 | |
POZ domain | WD40 repeat-like | 1 | 1 | |
ADC-like | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RNase III domain-like | 1 | 1 | |
F-box domain | Sec7 domain | 1 | 1 | |
Prokaryotic type I DNA topoisomerase | Zinc beta-ribbon | 1 | 1 | |
Somatomedin B domain | TSP-1 type 1 repeat | 1 | 1 | |
Carbamoyl phosphate synthetase, small subunit N-terminal domain | PreATP-grasp domain | 1 | 1 | |
Sec63 N-terminal domain-like | DNA/RNA polymerases | 1 | 1 | |
RING/U-box | beta-beta-alpha zinc fingers | 1 | 1 | |
UBA-like | WWE domain | 1 | 1 | |
EF-hand | SH2 domain | 1 | 1 | |
Ribokinase-like | Ribokinase-like | 1 | 1 | |
PGBD-like | Kringle-like | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | PRTase-like | 1 | 1 | |
UBA-like | UBA-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Polo-box domain | 1 | 1 | |
MoeA N-terminal region -like | MoeA C-terminal domain-like | 1 | 1 | |
Class II aaRS and biotin synthetases | Anticodon-binding domain of PheRS | 1 | 1 | |
Methionine synthase activation domain-like | Methionine synthase activation domain-like | 1 | 1 | |
Galactose-binding domain-like | beta-Galactosidase/glucuronidase domain | 1 | 1 | |
Putative DNA-binding domain | Class II aaRS and biotin synthetases | 1 | 1 | |
N-terminal domain of cbl (N-cbl) | EF-hand | 1 | 1 | |
(Trans)glycosidases | Six-hairpin glycosidases | 1 | 1 | |
Nucleotidylyl transferase | S15/NS1 RNA-binding domain | 1 | 1 | |
TRAF domain-like | Cysteine proteinases | 1 | 1 | |
PLP-dependent transferases | MOSC N-terminal domain-like | 1 | 1 | |
"Winged helix" DNA-binding domain | GroEL apical domain-like | 1 | 1 | |
AF1104-like | AF1104-like | 1 | 1 | |
Nitric oxide (NO) synthase oxygenase domain | Riboflavin synthase domain-like | 1 | 1 | |
RCC1/BLIP-II | PABC (PABP) domain | 1 | 1 | |
UDP-Glycosyltransferase/glycogen phosphorylase | Tudor/PWWP/MBT | 1 | 1 | |
GST C-terminal domain-like | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
Ribosomal protein S5 domain 2-like | Eukaryotic type KH-domain (KH-domain type I) | 1 | 1 | |
L9 N-domain-like | Ribonuclease H-like | 1 | 1 | |
WD40 repeat-like | Ypt/Rab-GAP domain of gyp1p | 1 | 1 | |
Cadherin-like | Dystroglycan, domain 2 | 1 | 1 | |
Diaminopimelate epimerase-like | Diaminopimelate epimerase-like | 1 | 1 | |
S-adenosylmethionine synthetase | S-adenosylmethionine synthetase | 1 | 1 | |
2Fe-2S ferredoxin-like | CO dehydrogenase molybdoprotein N-domain-like | 1 | 1 | |
Fibrinogen C-terminal domain-like | Fibrinogen C-terminal domain-like | 1 | 1 | |
Thiamin diphosphate-binding fold (THDP-binding) | DHS-like NAD/FAD-binding domain | 1 | 1 | |
HSP20-like chaperones | Ferredoxin reductase-like, C-terminal NADP-linked domain | 1 | 1 | |
TRAF domain-like | F-box domain | 1 | 1 | |
Intermediate filament protein, coiled coil region | Myosin rod fragments | 1 | 1 | |
Spermadhesin, CUB domain | Family A G protein-coupled receptor-like | 1 | 1 | |
p53-like transcription factors | DNA-binding protein LAG-1 (CSL) | 1 | 1 | |
Calponin-homology domain, CH-domain | Plakin repeat | 1 | 1 | |
Notch domain | Notch domain | 1 | 1 | |
L domain-like | NTF2-like | 1 | 1 | |
Cysteine proteinases | Galactose-binding domain-like | 1 | 1 | |
Cap-Gly domain | RNI-like | 1 | 1 | |
FYVE/PHD zinc finger | Chromo domain-like | 1 | 1 | |
Nucleotidylyl transferase | Class II aaRS and biotin synthetases | 1 | 1 | |
Carbonic anhydrase | Fibronectin type III | 1 | 1 | |
TSP-1 type 1 repeat | GFP-like | 1 | 1 | |
R3H domain | Ribonuclease H-like | 1 | 1 | |
Tudor/PWWP/MBT | BRCT domain | 1 | 1 | |
GFP-like | Thyroglobulin type-1 domain | 1 | 1 | |
Plexin repeat | Plexin repeat | 1 | 1 | |
Purple acid phosphatase, N-terminal domain | Metallo-dependent phosphatases | 1 | 1 | |
Histone H3 K4-specific methyltransferase SET7/9 N-terminal domain | SET domain | 1 | 1 | |
Release factor | Release factor | 1 | 1 | |
Surp module (SWAP domain) | Ubiquitin-like | 1 | 1 | |
PIN domain-like | Nucleic acid-binding proteins | 1 | 1 | |
Heme-dependent peroxidases | FnI-like domain | 1 | 1 | |
FAD-binding/transporter-associated domain-like | CO dehydrogenase molybdoprotein N-domain-like | 1 | 1 | |
WW domain | RING/U-box | 1 | 1 | |
RNA-binding domain, RBD | S-adenosyl-L-methionine-dependent methyltransferases | 1 | 1 | |
RING/U-box | Protein kinase-like (PK-like) | 1 | 1 | |
Tudor/PWWP/MBT | 6-phosphogluconate dehydrogenase C-terminal domain-like | 1 | 1 | |
HMA, heavy metal-associated domain | Calcium ATPase, transmembrane domain M | 1 | 1 | |
Band 7/SPFH domain | SCP-like | 1 | 1 | |
NAP-like | NAP-like | 1 | 1 | |
RNase III domain-like | RNase III domain-like | 1 | 1 | |
Immunoglobulin | GFP-like | 1 | 1 | |
Dom34/Pelota N-terminal domain-like | Translational machinery components | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | vWA-like | 1 | 1 | |
Nop domain | Nop domain | 1 | 1 | |
WW domain | EF-hand | 1 | 1 | |
ARM repeat | FYVE/PHD zinc finger | 1 | 1 | |
POZ domain | Skp1 dimerisation domain-like | 1 | 1 | |
PurM N-terminal domain-like | Class I glutamine amidotransferase-like | 1 | 1 | |
Tryptophan synthase beta subunit-like PLP-dependent enzymes | Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | 1 | |
E set domains | (Trans)glycosidases | 1 | 1 | |
"Winged helix" DNA-binding domain | Protein kinase-like (PK-like) | 1 | 1 | |
ARM repeat | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) | 1 | 1 | |
Dimerization cofactor of HNF-1 alpha | Homeodomain-like | 1 | 1 | |
Class II aaRS ABD-related | C-terminal domain of ProRS | 1 | 1 | |
Ubiquitin-like | Zn-binding ribosomal proteins | 1 | 1 | |
WW domain | Second domain of FERM | 1 | 1 | |
PLC-like phosphodiesterases | PLC-like phosphodiesterases | 1 | 1 | |
Plexin repeat | Protein kinase-like (PK-like) | 1 | 1 | |
RING/U-box | RNA-binding domain, RBD | 1 | 1 | |
Nucleotide-binding domain | FMN-linked oxidoreductases | 1 | 1 | |
Molybdenum cofactor biosynthesis proteins | MoeA N-terminal region -like | 1 | 1 | |
Concanavalin A-like lectins/glucanases | Family A G protein-coupled receptor-like | 1 | 1 | |
Ankyrin repeat | FabD/lysophospholipase-like | 1 | 1 | |
PUG domain-like | Galactose-binding domain-like | 1 | 1 | |
Integrin alpha N-terminal domain | Quinoprotein alcohol dehydrogenase-like | 1 | 1 | |
beta-sandwich domain of Sec23/24 | beta-sandwich domain of Sec23/24 | 1 | 1 | |
RING/U-box | Mib/herc2 domain-like | 1 | 1 | |
Periplasmic binding protein-like II | Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain | 1 | 1 | |
Kazal-type serine protease inhibitors | YVTN repeat-like/Quinoprotein amine dehydrogenase | 1 | 1 | |
Calponin-homology domain, CH-domain | PDZ domain-like | 1 | 1 | |
RNA-binding domain, RBD | Clavaminate synthase-like | 1 | 1 | |
Nucleotidylyl transferase | Class II aaRS ABD-related | 1 | 1 | |
Tex N-terminal region-like | Tex N-terminal region-like | 1 | 1 | |
ENTH/VHS domain | RNA-binding domain, RBD | 1 | 1 | |
NAD(P)-binding Rossmann-fold domains | Serine metabolism enzymes domain | 1 | 1 | |
Second domain of FERM | RING/U-box | 1 | 1 | |
Surp module (SWAP domain) | ENTH/VHS domain | 1 | 1 | |
Carboxypeptidase regulatory domain-like | YWTD domain | 1 | 1 | |
UBA-like | Hect, E3 ligase catalytic domain | 1 | 1 | |
TPR-like | UBA-like | 1 | 1 | |
Tudor/PWWP/MBT | NAD(P)-binding Rossmann-fold domains | 1 | 1 | |
IP3 receptor type 1 binding core, domain 2 | Concanavalin A-like lectins/glucanases | 1 | 1 | |
Metalloproteases ("zincins"), catalytic domain | Complement control module/SCR domain | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | Myosin phosphatase inhibitor 17kDa protein, CPI-17 | 1 | 1 | |
Protein kinase-like (PK-like) | Ypt/Rab-GAP domain of gyp1p | 1 | 1 | |
SEA domain | LDL receptor-like module | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Tryptophan synthase beta subunit-like PLP-dependent enzymes | 1 | 1 | |
Formate/glycerate dehydrogenase catalytic domain-like | DHS-like NAD/FAD-binding domain | 1 | 1 | |
ENTH/VHS domain | Clathrin adaptor appendage domain | 1 | 1 | |
BRCA2 tower domain | Nucleic acid-binding proteins | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | DHS-like NAD/FAD-binding domain | 1 | 1 | |
Ankyrin repeat | Pseudo ankyrin repeat-like | 1 | 1 | |
SAND domain-like | Bromodomain | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | Nucleotidylyl transferase | 1 | 1 | |
LDL receptor-like module | Galactose-binding domain-like | 1 | 1 | |
vWA-like | SAP domain | 1 | 1 | |
Nucleotidylyl transferase | Nucleic acid-binding proteins | 1 | 1 | |
Glucocorticoid receptor-like (DNA-binding domain) | ATP-dependent DNA ligase DNA-binding domain | 1 | 1 | |
POZ domain | Leucine zipper domain | 1 | 1 | |
FnI-like domain | Galactose-binding domain-like | 1 | 1 | |
SAM/Pointed domain | Toll/Interleukin receptor TIR domain | 1 | 1 | |
DNA repair protein MutS, domain I | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
Adenine nucleotide alpha hydrolases-like | GMP synthetase C-terminal dimerisation domain | 1 | 1 | |
Nucleotide-diphospho-sugar transferases | HAD-like | 1 | 1 | |
PKD domain | LDL receptor-like module | 1 | 1 | |
L domain-like | Heme-dependent peroxidases | 1 | 1 | |
Thioredoxin-like | Calcium-dependent phosphotriesterase | 1 | 1 | |
DNA-binding domain | DNA-glycosylase | 1 | 1 | |
Vacuolar ATP synthase subunit C | Vacuolar ATP synthase subunit C | 1 | 1 | |
Riboflavin synthase domain-like | Riboflavin synthase domain-like | 1 | 1 | |
Radical SAM enzymes | Molybdenum cofactor biosynthesis protein C, MoaC | 1 | 1 | |
Translation proteins | ThrRS/AlaRS common domain | 1 | 1 | |
PUA domain-like | Nucleotidylyl transferase | 1 | 1 | |
Chaperone J-domain | CSL zinc finger | 1 | 1 | |
N-terminal nucleophile aminohydrolases (Ntn hydrolases) | Adenine nucleotide alpha hydrolases-like | 1 | 1 | |
Immunoglobulin | Growth factor receptor domain | 1 | 1 | |
F-box domain | P-loop containing nucleoside triphosphate hydrolases | 1 | 1 | |
(Phosphotyrosine protein) phosphatases II | DNA ligase/mRNA capping enzyme, catalytic domain | 1 | 1 | |
CRAL/TRIO N-terminal domain | (Phosphotyrosine protein) phosphatases II | 1 | 1 | |
Ubiquitin-like | AN1-like Zinc finger | 1 | 1 | |
Nucleotide cyclase | TPR-like | 1 | 1 | |
FAD/NAD(P)-binding domain | 4Fe-4S ferredoxins | 1 | 1 | |
CCHHC domain | Acyl-CoA N-acyltransferases (Nat) | 1 | 1 | |
ARM repeat | L domain-like | 1 | 1 | |
Thiolase-like | SCP-like | 1 | 1 | |
P-loop containing nucleoside triphosphate hydrolases | RuvA domain 2-like | 1 | 1 | |
B-box zinc-binding domain | FYVE/PHD zinc finger | 1 | 1 | |
SAICAR synthase-like | N5-CAIR mutase (phosphoribosylaminoimidazole carboxylase, PurE) | 1 | 1 | |
SET domain | RuBisCo LSMT C-terminal, substrate-binding domain | 1 | 1 | |
PDZ domain-like | Myosin rod fragments | 1 | 1 | |
DEATH domain | PDZ domain-like | 1 | 1 | |
Tex N-terminal region-like | SH2 domain | 1 | 1 | |
SEA domain | SRCR-like | 1 | 1 | |
Cullin repeat-like | Cullin repeat-like | 1 | 1 | |
PurS-like | PurM N-terminal domain-like | 1 | 1 | |
2Fe-2S ferredoxin-like | CO dehydrogenase ISP C-domain like | 1 | 1 | |
Tubulin C-terminal domain-like | Tubulin C-terminal domain-like | 1 | 1 | |
Cap-Gly domain | Cysteine proteinases | 1 | 1 | |
Spectrin repeat | Fibronectin type III | 1 | 1 | |
SMAD/FHA domain | Protein kinase-like (PK-like) | 1 | 1 | |
"Winged helix" DNA-binding domain | SAICAR synthase-like | 1 | 1 | |
Glutathione synthetase ATP-binding domain-like | Phosphoglycerate mutase-like | 1 | 1 | |
FnI-like domain | Fibronectin type III | 1 | 1 | |
Prokaryotic type I DNA topoisomerase | Prokaryotic type I DNA topoisomerase | 1 | 1 | |
PH domain-like | Wiscott-Aldrich syndrome protein, WASP, C-terminal domain | 1 | 1 | |
HLH, helix-loop-helix DNA-binding domain | Orange domain-like | 1 | 1 | |
FAS1 domain | EGF/Laminin | 1 | 1 | |
The spindle assembly checkpoint protein mad2 | The spindle assembly checkpoint protein mad2 | 1 | 1 | |
FYVE/PHD zinc finger | SMAD/FHA domain | 1 | 1 | |
Nucleotidyltransferase | Poly A polymerase C-terminal region-like | 1 | 1 | |
DNA repair protein MutS, domain I | DNA repair protein MutS, domain II | 1 | 1 | |
p53-like transcription factors | DEATH domain | 1 | 1 | |
CO dehydrogenase ISP C-domain like | FAD-binding/transporter-associated domain-like | 1 | 1 | |
SH3-domain | TPR-like | 1 | 1 | |
HSP20-like chaperones | Cysteine proteinases | 1 | 1 | |
Ribosomal protein L25-like | Class II aaRS ABD-related | 1 | 1 | |
S15/NS1 RNA-binding domain | S15/NS1 RNA-binding domain | 1 | 1 | |
PUA domain-like | SWIB/MDM2 domain | 1 | 1 | |