SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Hydroxymethyl-, formyl- and related transferases

(show info)

Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Transferases [2] <10>(363|551) (398|460|240)
+ 1:   Transferring one-carbon groups [2.1] <4>(69|105) (78|71|28)
0:   Hydroxymethyl-, formyl- and related transferases [2.1.2] <14>(16|16) (17|11|8)
- 1:   3-methyl-2-oxobutanoate hydroxymethyltransferase [2.1.2.11](1|1) (1|0|0)
- 1:   Aminomethyltransferase [2.1.2.10](2|2) (2|1|0)
- 1:   D-alanine 2-hydroxymethyltransferase [2.1.2.7](0|0) (0|0|0)
- 1:   Deoxycytidylate 5-hydroxymethyltransferase [2.1.2.8](0|0) (1|0|0)
- 1:   Glutamate formimidoyltransferase [2.1.2.5](2|2) (2|2|1)
- 1:   Glycine formimidoyltransferase [2.1.2.4](0|0) (0|0|0)
- 1:   Glycine hydroxymethyltransferase [2.1.2.1](1|1) (1|0|0)
- 1:   Methionyl-tRNA formyltransferase [2.1.2.9](2|2) (2|1|0)
- 1:   Phosphoribosylaminoimidazolecarboxamide formyltran [2.1.2.3](2|2) (2|0|0)
- 1:   Phosphoribosylglycinamide formyltransferase [2.1.2.2](6|6) (6|6|6)
- 1:   Transferred entry: 2.1.1.74 [2.1.2.12](0|0) (0|0|0)
- 1:   Transferred entry: 2.1.2.13 [2.1.2.n1](0|0) (0|0|0)
- 1:   Transferred entry: 2.1.2.5 [2.1.2.6](0|0) (0|0|0)
- 1:   UDP-4-amino-4-deoxy-L-arabinose formyltransferase [2.1.2.13](3|3) (3|2|1)


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Aminomethyltransferase beta-barrel domain0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
Cytidine deaminase-like0Direct
FMT C-terminal domain-like0Direct
Methylglyoxal synthase-like0Direct
Formyltransferase0Direct
Folate-binding domain0Direct
Formiminotransferase domain of formiminotransferase-cyclodeaminase.0Direct
PLP-dependent transferases0Direct
Methenyltetrahydrofolate cyclohydrolase-like0.0000000000003583Direct
Rudiment single hybrid motif0.02166Inherited
PurM N-terminal domain-like1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
PurM C-terminal domain-like1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
PreATP-grasp domain1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP term FDR (all) Annotation (direct or inherited)
Tyrosine-dependent oxidoreductases0Direct
Inosicase0Direct
Aminomethyltransferase beta-barrel domain0Direct
Formiminotransferase domain of formiminotransferase-cyclodeaminase.0Direct
Formyltransferase0Direct
AICAR transformylase domain of bifunctional purine biosynthesis enzyme ATIC0Direct
Post formyltransferase domain0Direct
Aminomethyltransferase folate-binding domain0Direct
GABA-aminotransferase-like0Direct
Ketopantoate hydroxymethyltransferase PanB0Direct
Methenyltetrahydrofolate cyclohydrolase-like0.0000000000004295Direct
BC C-terminal domain-like0.02651Inherited
BC N-terminal domain-like0.4651Inherited
BC ATP-binding domain-like0.4887Inherited
PurM C-terminal domain-like1Inherited
PurM N-terminal domain-like1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Folate-binding domain0Direct
Aminomethyltransferase beta-barrel domain0Direct
Cytidine deaminase-like0Direct
PLP-dependent transferases0Direct
Formyltransferase0Direct
Phosphoenolpyruvate/pyruvate domain0Direct
FMT C-terminal domain-like0Direct
Formiminotransferase domain of formiminotransferase-cyclodeaminase.0Direct
Methylglyoxal synthase-like0Direct
Methenyltetrahydrofolate cyclohydrolase-like0.0000000000002665Direct
Rudiment single hybrid motif0.01875Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
Glutathione synthetase ATP-binding domain-like1Inherited
PurM C-terminal domain-like1Inherited
PreATP-grasp domain1Inherited
Thymidylate synthase/dCMP hydroxymethylase1Inherited
PurM N-terminal domain-like1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56042,53328
  • 56042 - PurM C-terminal domain-like
  • 53328 - Formyltransferase
  • 0Direct
    103025,101790
  • 103025 - Folate-binding domain
  • 101790 - Aminomethyltransferase beta-barrel domain
  • 0Direct
    53328,50486
  • 53328 - Formyltransferase
  • 50486 - FMT C-terminal domain-like
  • 0Direct
    55116,55116
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 0Direct
    55116,101262
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 101262 - Methenyltetrahydrofolate cyclohydrolase-like
  • 0Direct
    50486,51735
  • 50486 - FMT C-terminal domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    51246,55326
  • 51246 - Rudiment single hybrid motif
  • 55326 - PurM N-terminal domain-like
  • 0.000000000000632Direct
    56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0.01875Inherited
    56042,55326
  • 56042 - PurM C-terminal domain-like
  • 55326 - PurM N-terminal domain-like
  • 0.7503Inherited
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 1Inherited
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 1Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    53328,50486,51735
  • 53328 - Formyltransferase
  • 50486 - FMT C-terminal domain-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0Direct
    55326,56042,53328
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 53328 - Formyltransferase
  • 0Direct
    55116,55116,101262
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 55116 - Formiminotransferase domain of formiminotransferase-cyclodeaminase.
  • 101262 - Methenyltetrahydrofolate cyclohydrolase-like
  • 0Direct
    51246,55326,56042
  • 51246 - Rudiment single hybrid motif
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0.000000000000632Direct
    56059,51246,55326
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 55326 - PurM N-terminal domain-like
  • 0.000000000000632Direct
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0.01829Inherited
    56042,55326,56042
  • 56042 - PurM C-terminal domain-like
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0.7343Inherited
    55326,56042,55326
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 55326 - PurM N-terminal domain-like
  • 0.7477Inherited


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
    (show help)