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Non-specific serine/threonine protein kinase

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   root [root] <6>
+ + + 3:   Transferases [2] <10>(363|551) (398|460|240)
+ + 2:   Transferring phosphorous-containing groups [2.7] <13>(220|294) (251|300|176)
+ 1:   Protein-serine/threonine kinases [2.7.11] <31>(46|50) (57|86|38)
0:   Non-specific serine/threonine protein kinase [2.7.11.1](26|29) (34|56|23)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
DEATH domain0Direct
RCC1/BLIP-II0Direct
RNI-like0Direct
Myosin rod fragments0Direct
MAST3 pre-PK domain-like0Direct
KA1-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Ankyrin repeat0Direct
alpha-D-mannose-specific plant lectins0Direct
G protein-binding domain0Direct
SMAD/FHA domain0Direct
Spectrin repeat0Direct
Doublecortin (DC)0Direct
DBL homology domain (DH-domain)0Direct
MIT domain0Direct
L domain-like0Direct
Concanavalin A-like lectins/glucanases0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)2.368e-16Direct
CRAL/TRIO domain0.000000000004879Direct
PX domain0.000000000705Direct
ARM repeat0.000000001226Direct
UBA-like0.000000005279Direct
PYP-like sensor domain (PAS domain)0.000000358Direct
TPR-like0.000004641Direct
EF-hand0.0001582Direct
PDZ domain-like0.0002247Direct


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Family

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SCOP term FDR (all) Annotation (direct or inherited)
Kinase associated domain 1, KA10Direct
Spectrin repeat0Direct
Legume lectins0Direct
RIO1-like kinases0Direct
Regulator of chromosome condensation RCC10Direct
RhoA-binding domain0Direct
Doublecortin (DC)0Direct
MIT domain0Direct
Myosin rod fragments0Direct
alpha-D-mannose-specific plant lectins0Direct
DEATH domain, DD0Direct
FHA domain0Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0Direct
Polygalacturonase inhibiting protein PGIP0Direct
RWD domain0Direct
Ssp2 C-terminal domain-like0Direct
LIM domain0Direct
Ankyrin repeat0Direct
Histidine kinase0Direct
DBL homology domain (DH-domain)0Direct
MAST3 pre-PK domain-like0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)3.476e-16Direct
Motor proteins0.000000000009639Direct
Quinoprotein alcohol dehydrogenase-like0.00000000006169Direct
PX domain0.0000000003043Direct
Flavin-binding PAS domain0.00000002453Direct
Phoshoinositide 3-kinase (PI3K) helical domain0.0000007007Direct
Calmodulin-like0.00008592Direct
Ras-binding domain, RBD0.0004238Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Penicillin-binding protein 2x (pbp-2x), c-terminal domain0Direct
TAF(II)230 TBP-binding fragment0Direct
G protein-binding domain0Direct
Doublecortin (DC)0Direct
MAST3 pre-PK domain-like0Direct
Quinoprotein alcohol dehydrogenase-like0Direct
Tricorn protease domain 20Direct
alpha-D-mannose-specific plant lectins0Direct
L domain-like0Direct
DBL homology domain (DH-domain)0Direct
RNI-like0Direct
RCC1/BLIP-II0Direct
Cyclin-like0Direct
Concanavalin A-like lectins/glucanases0Direct
SMAD/FHA domain0Direct
Myosin rod fragments0Direct
DEATH domain0Direct
MIT domain0Direct
KA1-like0Direct
Spectrin repeat0Direct
Ankyrin repeat0Direct
FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)1.756e-16Direct
CRAL/TRIO domain0.000000000003677Direct
PX domain0.0000000005446Direct
ARM repeat0.00000000098Direct
UBA-like0.000000009828Direct
C-type lectin-like0.0000000115Direct
PYP-like sensor domain (PAS domain)0.0000002821Direct
Chaperone J-domain0.0000005998Direct
GTPase activation domain, GAP0.0000005998Direct
TPR-like0.000003727Direct
EF-hand0.0001339Direct
Bromodomain0.0001551Direct
PDZ domain-like0.0001904Direct

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52058,52047
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 0Direct
    56112,48403
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
  • 0Direct
    49899,56112
  • 49899 - Concanavalin A-like lectins/glucanases
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53067,56112
  • 53067 - Actin-like ATPase domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    47986,56112
  • 47986 - DEATH domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52047,56112
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,56112
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    48371,48371
  • 48371 - ARM repeat
  • 48371 - ARM repeat
  • 0Direct
    116846,116846
  • 116846 - MIT domain
  • 116846 - MIT domain
  • 0Direct
    50998,56112
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    89837,89837
  • 89837 - Doublecortin (DC)
  • 89837 - Doublecortin (DC)
  • 0Direct
    52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0Direct
    56112,103243
  • 56112 - Protein kinase-like (PK-like)
  • 103243 - KA1-like
  • 0Direct
    48726,56112
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,48371
  • 56112 - Protein kinase-like (PK-like)
  • 48371 - ARM repeat
  • 0Direct
    52087,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 0Direct
    52058,52540
  • 52058 - L domain-like
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    56112,55681
  • 56112 - Protein kinase-like (PK-like)
  • 55681 - Class II aaRS and biotin synthetases
  • 0Direct
    47370,47370
  • 47370 - Bromodomain
  • 47370 - Bromodomain
  • 0Direct
    55073,56112
  • 55073 - Nucleotide cyclase
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52047,52058
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0Direct
    57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0Direct
    56112,50998
  • 56112 - Protein kinase-like (PK-like)
  • 50998 - Quinoprotein alcohol dehydrogenase-like
  • 0Direct
    48065,50729
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    64268,56112
  • 64268 - PX domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 0Direct
    56112,90257
  • 56112 - Protein kinase-like (PK-like)
  • 90257 - Myosin rod fragments
  • 0Direct
    48403,56112
  • 48403 - Ankyrin repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,54928
  • 56112 - Protein kinase-like (PK-like)
  • 54928 - RNA-binding domain, RBD
  • 0Direct
    46785,56112
  • 46785 - "Winged helix" DNA-binding domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52047,52047
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 0Direct
    56112,50985
  • 56112 - Protein kinase-like (PK-like)
  • 50985 - RCC1/BLIP-II
  • 0Direct
    50729,69322
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0Direct
    46966,46966
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    56112,48452
  • 56112 - Protein kinase-like (PK-like)
  • 48452 - TPR-like
  • 0Direct
    49879,56112
  • 49879 - SMAD/FHA domain
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    50156,56112
  • 50156 - PDZ domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    53850,56112
  • 53850 - Periplasmic binding protein-like II
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,52799
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 0Direct
    48371,56112
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    47212,56112
  • 47212 - FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
  • 56112 - Protein kinase-like (PK-like)
  • 1.756e-16Direct
    50729,57889
  • 50729 - PH domain-like
  • 57889 - Cysteine-rich domain
  • 0.000000000000002087Direct
    49265,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0.0000000000001068Direct
    50729,50044
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0.00000000003241Direct
    56112,50044
  • 56112 - Protein kinase-like (PK-like)
  • 50044 - SH3-domain
  • 0.0000000115Direct
    56112,52540
  • 56112 - Protein kinase-like (PK-like)
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.00000004184Direct
    48403,52540
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000000204Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.000000204Direct
    49562,48371
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 0.000000299Direct
    48403,47769
  • 48403 - Ankyrin repeat
  • 47769 - SAM/Pointed domain
  • 0.000001374Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0.000004777Direct
    52799,49562
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0.00002544Direct
    56112,47473
  • 56112 - Protein kinase-like (PK-like)
  • 47473 - EF-hand
  • 0.0001339Direct
    56112,56112
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.0002693Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52087,46966,46966
  • 52087 - CRAL/TRIO domain
  • 46966 - Spectrin repeat
  • 46966 - Spectrin repeat
  • 0Direct
    48726,49265,48726
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 0Direct
    52058,52058,56112
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52047,52047,52058
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0Direct
    57716,57716,57716
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 0Direct
    57716,57716,50156
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 0Direct
    56112,52799,49562
  • 56112 - Protein kinase-like (PK-like)
  • 52799 - (Phosphotyrosine protein) phosphatases II
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    49265,48726,49265
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0Direct
    52047,52047,56112
  • 52047 - RNI-like
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    57889,50729,69322
  • 57889 - Cysteine-rich domain
  • 50729 - PH domain-like
  • 69322 - Tricorn protease domain 2
  • 0Direct
    56112,48726,48726
  • 56112 - Protein kinase-like (PK-like)
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    52058,52047,56112
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    48065,50729,50044
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 50044 - SH3-domain
  • 0Direct
    56112,48403,52540
  • 56112 - Protein kinase-like (PK-like)
  • 48403 - Ankyrin repeat
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0Direct
    48726,48726,56112
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,52047,52058
  • 52058 - L domain-like
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 0Direct
    52047,52058,56112
  • 52047 - RNI-like
  • 52058 - L domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    53850,53850,56112
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    56112,116846,116846
  • 56112 - Protein kinase-like (PK-like)
  • 116846 - MIT domain
  • 116846 - MIT domain
  • 0Direct
    57716,50156,56112
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 50156 - PDZ domain-like
  • 56112 - Protein kinase-like (PK-like)
  • 0Direct
    52058,52058,52058
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 52058 - L domain-like
  • 0.000000000007873Direct
    49265,48726,48726
  • 49265 - Fibronectin type III
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.0000000005755Direct
    49562,48371,56112
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 48371 - ARM repeat
  • 56112 - Protein kinase-like (PK-like)
  • 0.000000299Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
    (show help)