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Carboxylic ester hydrolases

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Hydrolases [3] <13>(329|528) (368|389|207)
+ 1:   Acting on ester bonds [3.1] <20>(124|170) (142|112|48)
0:   Carboxylic ester hydrolases [3.1.1] <91>(22|34) (27|13|0)
- 1:   1,4-lactonase [3.1.1.25](0|0) (0|0|0)
- 1:   1-alkyl-2-acetylglycerophosphocholine esterase [3.1.1.47](1|1) (3|1|0)
- 1:   11-cis-retinyl-palmitate hydrolase [3.1.1.63](0|0) (0|0|0)
- 1:   2-pyrone-4,6-dicarboxylate lactonase [3.1.1.57](0|0) (0|0|0)
- 1:   3-oxoadipate enol-lactonase [3.1.1.24](0|0) (0|0|0)
- 1:   4-methyloxaloacetate esterase [3.1.1.44](0|0) (0|0|0)
- 1:   4-pyridoxolactonase [3.1.1.27](0|0) (0|0|0)
- 1:   5-(3,4-diacetoxybut-1-ynyl)-2,2'-bithiophene deace [3.1.1.66](0|0) (0|0|0)
- 1:   6-acetylglucose deacetylase [3.1.1.33](0|0) (0|0|0)
- 1:   6-phosphogluconolactonase [3.1.1.31](2|2) (3|1|0)
- 1:   Acetoxybutynylbithiophene deacetylase [3.1.1.54](0|0) (0|0|0)
- 1:   Acetylajmaline esterase [3.1.1.80](0|0) (0|0|0)
- 1:   Acetylalkylglycerol acetylhydrolase [3.1.1.71](0|0) (0|0|0)
- 1:   Acetylcholinesterase [3.1.1.7](1|1) (1|0|0)
- 1:   Acetylesterase [3.1.1.6](0|0) (0|0|0)
- 1:   Acetylsalicylate deacetylase [3.1.1.55](0|0) (0|0|0)
- 1:   Acetylxylan esterase [3.1.1.72](1|0) (1|1|0)
- 1:   Actinomycin lactonase [3.1.1.39](0|0) (0|0|0)
- 1:   Acylcarnitine hydrolase [3.1.1.28](0|0) (0|0|0)
- 1:   Acylglycerol lipase [3.1.1.23](1|1) (1|0|0)
- 1:   Acyloxyacyl hydrolase [3.1.1.77](0|0) (2|0|0)
- 1:   All-trans-retinyl ester 13-cis isomerohydrolase [3.1.1.90](0|0) (0|0|0)
- 1:   Alpha-amino-acid esterase [3.1.1.43](0|0) (0|0|0)
- 1:   Aminoacyl-tRNA hydrolase [3.1.1.29](3|3) (3|0|0)
- 1:   Arylesterase [3.1.1.2](1|1) (1|0|0)
- 1:   Bis(2-ethylhexyl)phthalate esterase [3.1.1.60](0|0) (0|0|0)
- 1:   Carboxylesterase [3.1.1.1](1|2) (1|1|0)
- 1:   Carboxymethylenebutenolidase [3.1.1.45](1|1) (1|0|0)
- 1:   Cephalosporin-C deacetylase [3.1.1.41](0|0) (0|0|0)
- 1:   Cetraxate benzylesterase [3.1.1.70](0|0) (0|0|0)
- 1:   Chlorogenate hydrolase [3.1.1.42](0|0) (0|0|0)
- 1:   Chlorophyllase [3.1.1.14](0|0) (0|0|0)
- 1:   Cholinesterase [3.1.1.8](1|1) (1|0|0)
- 1:   Cocaine esterase [3.1.1.84](0|0) (0|0|0)
- 1:   Cutinase [3.1.1.74](1|1) (1|0|0)
- 1:   D-arabinonolactonase [3.1.1.30](0|0) (0|0|0)
- 1:   Deleted entry [3.1.1.21](0|0) (0|0|0)
- 1:   Deleted entry [3.1.1.9](0|0) (0|0|0)
- 1:   Deoxylimonate A-ring-lactonase [3.1.1.46](0|0) (0|0|0)
- 1:   Dihydrocoumarin hydrolase [3.1.1.35](0|0) (0|0|0)
- 1:   Fatty-acyl-ethyl-ester synthase [3.1.1.67](0|0) (0|0|0)
- 1:   Feruloyl esterase [3.1.1.73](1|1) (1|0|0)
- 1:   Fumonisin B1 esterase [3.1.1.87](0|0) (0|0|0)
- 1:   Fusarinine-C ornithinesterase [3.1.1.48](0|0) (0|0|0)
- 1:   Galactolipase [3.1.1.26](2|2) (2|1|0)
- 1:   Gluconolactonase [3.1.1.17](1|1) (1|0|0)
- 1:   Hormone-sensitive lipase [3.1.1.79](0|1) (0|0|0)
- 1:   Hydroxybutyrate-dimer hydrolase [3.1.1.22](1|0) (1|0|0)
- 1:   Juvenile-hormone esterase [3.1.1.59](0|0) (0|0|0)
- 1:   L-arabinonolactonase [3.1.1.15](0|0) (0|0|0)
- 1:   L-rhamnono-1,4-lactonase [3.1.1.65](0|0) (0|0|0)
- 1:   Limonin-D-ring-lactonase [3.1.1.36](0|0) (0|0|0)
- 1:   Lipoprotein lipase [3.1.1.34](2|1) (2|1|0)
- 1:   Lysophospholipase [3.1.1.5](3|3) (6|4|0)
- 1:   Methylumbelliferyl-acetate deacetylase [3.1.1.56](0|0) (0|0|0)
- 1:   Monoterpene epsilon-lactone hydrolase [3.1.1.83](0|0) (0|0|0)
- 1:   N-acetylgalactosaminoglycan deacetylase [3.1.1.58](0|0) (0|0|0)
- 1:   Orsellinate-depside hydrolase [3.1.1.40](0|0) (0|0|0)
- 1:   Pectinesterase [3.1.1.11](2|2) (2|1|0)
- 1:   Pheophorbidase [3.1.1.82](0|0) (0|0|0)
- 1:   Phorbol-diester hydrolase [3.1.1.51](0|0) (0|0|0)
- 1:   Phosphatidylinositol deacylase [3.1.1.52](0|0) (0|0|0)
- 1:   Phospholipase A(1) [3.1.1.32](2|2) (2|0|0)
- 1:   Phospholipase A(2) [3.1.1.4](3|5) (3|2|0)
- 1:   Pimelyl-[acyl-carrier protein] methyl ester estera [3.1.1.85](1|1) (1|0|0)
- 1:   Poly(3-hydroxybutyrate) depolymerase [3.1.1.75](0|0) (0|0|0)
- 1:   Poly(3-hydroxyoctanoate) depolymerase [3.1.1.76](0|0) (0|0|0)
- 1:   Polyneuridine-aldehyde esterase [3.1.1.78](0|0) (0|0|0)
- 1:   Protein phosphatase methylesterase-1 [3.1.1.89](1|0) (1|0|0)
- 1:   Protein-glutamate methylesterase [3.1.1.61](2|2) (2|1|0)
- 1:   Pyrethroid hydrolase [3.1.1.88](0|0) (0|0|0)
- 1:   Quorum-quenching N-acyl-homoserine lactonase [3.1.1.81](2|1) (2|0|0)
- 1:   Retinoid isomerohydrolase [3.1.1.64](0|0) (0|0|0)
- 1:   Rhamnogalacturonan acetylesterase [3.1.1.86](0|0) (0|0|0)
- 1:   Sialate O-acetylesterase [3.1.1.53](3|3) (3|1|0)
- 1:   Sinapine esterase [3.1.1.49](0|0) (0|0|0)
- 1:   Steroid-lactonase [3.1.1.37](0|0) (0|0|0)
- 1:   Sterol esterase [3.1.1.13](1|1) (1|0|0)
- 1:   Tannase [3.1.1.20](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.1.1 [3.1.1.12](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.1.17 [3.1.1.18](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.1.24 and 5.3.3.4 [3.1.1.16](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.103 [3.1.1.n1](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.47 [3.1.1.62](0|0) (0|0|0)
- 1:   Transferred entry: 3.5.1.89 [3.1.1.69](0|0) (0|0|0)
- 1:   Triacetate-lactonase [3.1.1.38](0|0) (0|0|0)
- 1:   Triacylglycerol lipase [3.1.1.3](2|6) (2|1|0)
- 1:   Tropinesterase [3.1.1.10](0|0) (0|0|0)
- 1:   Uronolactonase [3.1.1.19](0|0) (0|0|0)
- 1:   Wax-ester hydrolase [3.1.1.50](0|0) (0|0|0)
- 1:   Xylono-1,4-lactonase [3.1.1.68](0|0) (0|0|0)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
cAMP-binding domain-like0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
FabD/lysophospholipase-like0Direct
Methylesterase CheB, C-terminal domain0Direct
CheY-like0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
Phospholipase A2, PLA20Direct
Nitrous oxide reductase, N-terminal domain0Direct
SGNH hydrolase0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
alpha/beta-Hydrolases0Direct
Peptidyl-tRNA hydrolase-like0Direct
Peptidyl-tRNA hydrolase II0Direct
Viral protein domain0Direct
Influenza hemagglutinin (stalk)0Direct
Calcium-dependent phosphotriesterase0Direct
Pectin lyase-like0Direct
NagB/RpiA/CoA transferase-like0.00000000000001442Direct
Ankyrin repeat0.0008122Direct
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Metallo-hydrolase/oxidoreductase1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP term FDR (all) Annotation (direct or inherited)
Vertebrate phospholipase A20Direct
Pancreatic lipase, N-terminal domain0Direct
Pectin methylesterase0Direct
Patatin0Direct
Esterase domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Influenza hemagglutinin (stalk)0Direct
Biotin biosynthesis protein BioH0Direct
Acetylcholinesterase-like0Direct
Methylesterase CheB, C-terminal domain0Direct
Carboxylesterase0Direct
Acetylhydrolase0Direct
Dienelactone hydrolase0Direct
cAMP-binding domain0Direct
Peptidyl-tRNA hydrolase II0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Fungal lipases0Direct
Lysophospholipase0Direct
Plant invertase/pectin methylesterase inhibitor0Direct
Cutinase-like0Direct
NagB-like0Direct
Bacterial lipase0Direct
CheY-related0Direct
Nitrous oxide reductase, N-terminal domain0Direct
Colipase-binding domain0Direct
Peptidyl-tRNA hydrolase-like0Direct
Peptidyl-tRNA hydrolase domain0Direct
Hemagglutinin domain of haemagglutinin-esterase-fusion glycoprotein HEF10Direct
Insect phospholipase A20Direct
Gastric lipase0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
SGL-like0.0000000006901Direct
Carbon-carbon bond hydrolase0.0000002221Direct
Ankyrin repeat0.0006358Direct
PLC-like (P variant)1Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Plant invertase/pectin methylesterase inhibitor0Direct
Outer membrane phospholipase A (OMPLA)0Direct
Lipase/lipooxygenase domain (PLAT/LH2 domain)0Direct
Influenza hemagglutinin (stalk)0Direct
Calcium-dependent phosphotriesterase0Direct
Pectin lyase-like0Direct
alpha/beta-Hydrolases0Direct
Viral protein domain0Direct
SGNH hydrolase0Direct
Peptidyl-tRNA hydrolase domain-like0Direct
FabD/lysophospholipase-like0Direct
Peptidyl-tRNA hydrolase-like0Direct
Peptidyl-tRNA hydrolase II0Direct
Phospholipase A2, PLA20Direct
Nitrous oxide reductase, N-terminal domain0Direct
cAMP-binding domain-like0Direct
Methylesterase CheB, C-terminal domain0Direct
CheY-like0Direct
NagB/RpiA/CoA transferase-like0.00000000000001068Direct
Autotransporter0.000004686Direct
Glutaminase/Asparaginase0.0005867Direct
Ankyrin repeat0.0006825Direct
Putative isomerase YbhE0.01802Inherited
Saposin0.1284Inherited
Concanavalin A-like lectins/glucanases0.5892Inherited
C2 domain (Calcium/lipid-binding domain, CaLB)1Inherited
Metallo-hydrolase/oxidoreductase1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0Direct
    49562,52151
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52266,49818
  • 52266 - SGNH hydrolase
  • 49818 - Viral protein domain
  • 0Direct
    53474,53474
  • 53474 - alpha/beta-Hydrolases
  • 53474 - alpha/beta-Hydrolases
  • 0Direct
    101148,51126
  • 101148 - Plant invertase/pectin methylesterase inhibitor
  • 51126 - Pectin lyase-like
  • 0Direct
    52151,52151
  • 52151 - FabD/lysophospholipase-like
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    52172,52738
  • 52172 - CheY-like
  • 52738 - Methylesterase CheB, C-terminal domain
  • 0Direct
    50974,50974
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 50974 - Nitrous oxide reductase, N-terminal domain
  • 0Direct
    52266,103515
  • 52266 - SGNH hydrolase
  • 103515 - Autotransporter
  • 0Direct
    51206,51206
  • 51206 - cAMP-binding domain-like
  • 51206 - cAMP-binding domain-like
  • 0Direct
    48403,52151
  • 48403 - Ankyrin repeat
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    53774,48403
  • 53774 - Glutaminase/Asparaginase
  • 48403 - Ankyrin repeat
  • 0.000000041Direct
    53474,53335
  • 53474 - alpha/beta-Hydrolases
  • 53335 - S-adenosyl-L-methionine-dependent methyltransferases
  • 0.0000001999Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
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