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Thiolester hydrolases

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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Hydrolases [3] <13>(329|528) (368|389|207)
+ 1:   Acting on ester bonds [3.1] <20>(124|170) (142|112|48)
0:   Thiolester hydrolases [3.1.2] <30>(12|14) (13|9|4)
- 1:   (S)-methylmalonyl-CoA hydrolase [3.1.2.17](0|0) (0|0|0)
- 1:   1,4-dihydroxy-2-naphthoyl-CoA hydrolase [3.1.2.28](1|1) (1|0|0)
- 1:   3-hydroxyisobutyryl-CoA hydrolase [3.1.2.4](1|1) (1|0|0)
- 1:   4-hydroxybenzoyl-CoA thioesterase [3.1.2.23](0|0) (0|0|0)
- 1:   ADP-dependent medium-chain-acyl-CoA hydrolase [3.1.2.19](0|0) (0|0|0)
- 1:   ADP-dependent short-chain-acyl-CoA hydrolase [3.1.2.18](0|0) (0|0|0)
- 1:   Acetoacetyl-CoA hydrolase [3.1.2.11](0|0) (0|0|0)
- 1:   Acetyl-CoA hydrolase [3.1.2.1](1|1) (2|3|1)
- 1:   Acyl-CoA hydrolase [3.1.2.20](0|0) (0|0|0)
- 1:   Bile-acid-CoA hydrolase [3.1.2.26](0|0) (0|0|0)
- 1:   Choloyl-CoA hydrolase [3.1.2.27](0|0) (1|1|0)
- 1:   Citrate-lyase deacetylase [3.1.2.16](0|0) (0|0|0)
- 1:   Deleted entry [3.1.2.9](0|0) (0|0|0)
- 1:   Dodecanoyl-[acyl-carrier-protein] hydrolase [3.1.2.21](0|0) (0|0|0)
- 1:   Fluoroacetyl-CoA thioesterase [3.1.2.29](0|0) (0|0|0)
- 1:   Formyl-CoA hydrolase [3.1.2.10](0|0) (0|0|0)
- 1:   Glutathione thiolesterase [3.1.2.7](0|0) (0|0|0)
- 1:   Hydroxyacylglutathione hydrolase [3.1.2.6](1|1) (1|0|0)
- 1:   Hydroxymethylglutaryl-CoA hydrolase [3.1.2.5](0|0) (0|0|0)
- 1:   Oleoyl-[acyl-carrier-protein] hydrolase [3.1.2.14](8|8) (8|6|3)
- 1:   Palmitoyl-CoA hydrolase [3.1.2.2](1|0) (1|1|0)
- 1:   Palmitoyl-protein hydrolase [3.1.2.22](1|1) (1|0|0)
- 1:   Phenylacetyl-CoA hydrolase [3.1.2.25](0|0) (0|0|0)
- 1:   S-formylglutathione hydrolase [3.1.2.12](1|1) (1|0|0)
- 1:   S-succinylglutathione hydrolase [3.1.2.13](0|0) (0|0|0)
- 1:   Succinyl-CoA hydrolase [3.1.2.3](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.2.28 [3.1.2.n1](0|0) (0|0|0)
- 1:   Transferred entry: 3.1.2.6 [3.1.2.8](0|0) (0|0|0)
- 1:   Transferred entry: 3.13.1.3 [3.1.2.24](0|0) (0|0|0)
- 1:   Ubiquitin thiolesterase [3.1.2.15](0|0) (0|0|0)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
Metallo-hydrolase/oxidoreductase0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
alpha/beta-Hydrolases0.0000000004291Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.000000002556Direct
ACP-like0.0000002007Direct
ClpP/crotonase0.00001714Direct
NagB/RpiA/CoA transferase-like0.00002533Direct
GroES-like0.001002Inherited
FabD/lysophospholipase-like0.004241Inherited
Thiolase-like0.0154Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited
NAD(P)-binding Rossmann-fold domains1Inherited


Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP term FDR (all) Annotation (direct or inherited)
4HBT-like0Direct
FabD-like0Direct
Thioesterases0Direct
Glyoxalase II (hydroxyacylglutathione hydrolase)0Direct
CoA transferase alpha subunit-like0Direct
Hypothetical esterase YJL068C0Direct
Crotonase-like3.476e-16Direct
Acyl-carrier protein (ACP)3.476e-16Direct
Thioesterase domain of polypeptide, polyketide and fatty acid synthases0.000000000000001037Direct
MaoC-like0.000000000002919Direct
Thiolase-related0.0001087Direct
Alcohol dehydrogenase-like, C-terminal domain0.0007308Direct
Alcohol dehydrogenase-like, N-terminal domain0.0009207Direct
Tyrosine-dependent oxidoreductases0.01624Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Metallo-hydrolase/oxidoreductase0Direct
Thioesterase/thiol ester dehydrase-isomerase0Direct
alpha/beta-Hydrolases0.0000000003184Direct
Probable ACP-binding domain of malonyl-CoA ACP transacylase0.000000001989Direct
ACP-like0.0000001594Direct
Bet v1-like0.000002775Direct
ClpP/crotonase0.0000137Direct
NagB/RpiA/CoA transferase-like0.00002045Direct
GroES-like0.0008418Direct
FabD/lysophospholipase-like0.00353Inherited
Thiolase-like0.01332Inherited
NAD(P)-binding Rossmann-fold domains1Inherited
S-adenosyl-L-methionine-dependent methyltransferases1Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    54637,52151
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 52151 - FabD/lysophospholipase-like
  • 0Direct
    100950,100950
  • 100950 - NagB/RpiA/CoA transferase-like
  • 100950 - NagB/RpiA/CoA transferase-like
  • 0Direct
    54637,54637
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 0Direct
    47336,53474
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 0.000000000000001568Direct
    51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.00000000001514Direct
    51735,51735
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.00000000005883Direct
    52151,55048
  • 52151 - FabD/lysophospholipase-like
  • 55048 - Probable ACP-binding domain of malonyl-CoA ACP transacylase
  • 0.000000001989Direct
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0008135Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    54637,54637,55961
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 54637 - Thioesterase/thiol ester dehydrase-isomerase
  • 55961 - Bet v1-like
  • 0Direct
    51735,47336,53474
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 53474 - alpha/beta-Hydrolases
  • 3.502e-16Direct
    50129,51735,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.0000000000001971Direct
    51735,51735,47336
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 47336 - ACP-like
  • 0.000000000007934Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
    Plot tree as:   Download Newick format tree:
    (show help)