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Acting on acid anhydrides
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Enzyme Commission (EC)
Each enzyme is allocated a four-digit EC number, the first three digits of which define the reaction catalysed and the fourth of which is a unique identifier (serial number). Each enzyme is also assigned a systematic name that uniquely defines the reaction catalysed. To navigate hierarchical structure of EC, we display all parental EC terms to the current EC term of interest ordered by their shortest distances to the current term. Also, only direct children EC terms of the current EC term are listed.
Structural Classification of Proteins (SCOP)
SCOP classifies evolutionary-related domains into Superfamily level and Family level. Accordingly, we have generated the domain-centric EC annotations for each of the three concepts at each of the two domain levels.
Structural Domain Enzyme Commission Ontology (SDEO)
As domain-centric ontology, SDEO only refers to those EC terms which are the most informative to annotate SCOP domains.
EC annotations for SCOP domains
For details, please visit Documentation: EC annotations for SCOP domains. Therein, we provide several relevant files ( Data Availability) for the download, including an annotation file (i.e., Domain2EC.txt) and the corresponding ontology (i.e., SDEO.txt).
Supra-domain Enzyme Commission Ontology (SPEO)
As an extension, SPEO includes those EC terms which are the most informative to annotate supra-domains and individual SCOP domains at the Superfamily level.
EC annotations for Supra-domains
For details, please visit Documentation: EC annotations for Supra-domains. Therein, we provide several relevant files ( Data Availability) for the download, including a annotation file (i.e., SP2EC.txt) and an ontology (i.e., SPEO.txt). For the sake of being browsable, listed below are those supra-domains (single, dual, triple, quad).
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Root: EC Hierarchy (from IntEnz release 70)
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Superfamily(show details)
Superfamily domains annotated to this EC term (SDEO level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
SCOP term |
FDR (all) |
Annotation (direct or inherited) |
RuvA domain 2-like | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
BRK domain-like | 0 | DIRECT |
Translation proteins | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Flavivirus capsid protein C | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
HIT-like | 0 | DIRECT |
DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Positive stranded ssRNA viruses | 0 | DIRECT |
all-alpha NTP pyrophosphatases | 0 | DIRECT |
"Winged helix" DNA-binding domain | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
EndoU-like | 0 | DIRECT |
C-terminal domain of Ku80 | 0 | DIRECT |
HAD-like | 0 | DIRECT |
Origin of replication-binding domain, RBD-like | 0 | DIRECT |
Rap30/74 interaction domains | 0 | DIRECT |
EF-G C-terminal domain-like | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
Inorganic pyrophosphatase | 0 | DIRECT |
HMA, heavy metal-associated domain | 0 | DIRECT |
Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
DHH phosphoesterases | 0 | DIRECT |
MOP-like | 0 | DIRECT |
N-terminal domain of DnaB helicase | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
Nudix | 0 | DIRECT |
dUTPase-like | 0 | DIRECT |
ITPase-like | 0 | DIRECT |
Acylphosphatase/BLUF domain-like | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
Tudor/PWWP/MBT | 0.0000000000008956 | DIRECT |
Chromo domain-like | 0.000000000001708 | DIRECT |
SAP domain | 0.00000000002257 | DIRECT |
Hedgehog/intein (Hint) domain | 0.00000000002567 | DIRECT |
Viral glycoprotein, central and dimerisation domains | 0.0000000004925 | DIRECT |
vWA-like | 0.000000001101 | DIRECT |
Homing endonucleases | 0.000000003686 | DIRECT |
Prokaryotic type I DNA topoisomerase | 0.000005958 | DIRECT |
Coronavirus NSP8-like | 0.00002631 | DIRECT |
Coronavirus NSP7-like | 0.00002631 | DIRECT |
Replicase NSP9 | 0.00002631 | DIRECT |
Coronavirus NSP10-like | 0.00002631 | DIRECT |
MIT domain | 0.00003161 | DIRECT |
E set domains | 0.0003008 | DIRECT |
HRDC-like | 0.0005332 | DIRECT |
Somatomedin B domain | 0.001225 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
NSP3A-like | 0.001329 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an || RNA helicase |
WW domain | 0.003595 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
FYVE/PHD zinc finger | 0.008364 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an |
RNA-binding domain, RBD | 0.01123 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
His-Me finger endonucleases | 0.0196 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
R3H domain | 0.03241 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.1955 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorous-containing anhydrides |
Trypsin-like serine proteases | 0.2689 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
CYTH-like phosphatases | 0.3199 | INHERITED FROM: In phosphorous-containing anhydrides || Thiamine-triphosphatase |
Ankyrin repeat | 0.4016 | INHERITED FROM: NAD(+) diphosphatase |
HD-domain/PDEase-like | 0.7809 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha |
UBA-like | 0.8024 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an |
Clavaminate synthase-like | 0.8245 | INHERITED FROM: RNA helicase |
PH domain-like | 1 | INHERITED FROM: Dynamin GTPase || Acting on GTP; involved in cellular and subcellula |
DNA-binding domain of retroviral integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
HisI-like | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Phosphoribosyl-ATP diphosphatase |
Macro domain-like | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
Acid proteases | 1 | INHERITED FROM: dUTP diphosphatase |
S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Nucleoside-triphosphatase || RNA helicase |
Alkaline phosphatase-like | 1 | INHERITED FROM: Nucleotide diphosphatase |
Actin-like ATPase domain | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha || Exopolyphosphatase |
Ribonuclease Rh-like | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
ADC-like | 1 | INHERITED FROM: Vesicle-fusing ATPase |
SurE-like | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Exopolyphosphatase |
Acid phosphatase/Vanadium-dependent haloperoxidase | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Dolichyldiphosphatase |
Retrovirus zinc finger-like domains | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
N-terminal Zn binding domain of HIV integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: RNA helicase |
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Family(show details)
Family domains annotated to this (SDEO level: Least Informative)
Highlighted in gray are those with FDR_all>0.001
SCOP term |
FDR (all) |
Annotation (direct or inherited) |
Nsp15 C-terminal domain-like | 0 | DIRECT |
Manganese-dependent inorganic pyrophosphatase (family II) | 0 | DIRECT |
DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
MutT-like | 0 | DIRECT |
NADH pyrophosphatase | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
Meta-cation ATPase, catalytic domain P | 0 | DIRECT |
DNA helicase RuvA subunit, N-terminal domain | 0 | DIRECT |
Inorganic pyrophosphatase | 0 | DIRECT |
G proteins | 0 | DIRECT |
ABC transporter ATPase domain-like | 0 | DIRECT |
Replication initiation protein E1 | 0 | DIRECT |
ABC-transporter additional domain | 0 | DIRECT |
RNA helicase | 0 | DIRECT |
dUTPase-like | 0 | DIRECT |
Chromo domain | 0 | DIRECT |
Acylphosphatase-like | 0 | DIRECT |
DNA-binding domain from rap30 | 0 | DIRECT |
Helicase-like "domain" of reverse gyrase | 0 | DIRECT |
Sec63 N-terminal domain | 0 | DIRECT |
RecA protein-like (ATPase-domain) | 0 | DIRECT |
C-terminal domain of Ku80 | 0 | DIRECT |
Tandem AAA-ATPase domain | 0 | DIRECT |
Ku70 subunit middle domain | 0 | DIRECT |
DNA helicase RuvA subunit, middle domain | 0 | DIRECT |
Ku80 subunit N-terminal domain | 0 | DIRECT |
Nsp15 N-terminal domain-like | 0 | DIRECT |
HRDC domain from helicases | 0 | DIRECT |
Ppx associated domain | 0 | DIRECT |
RecQ helicase DNA-binding domain-like | 0 | DIRECT |
RNA-dependent RNA-polymerase | 0 | DIRECT |
Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | DIRECT |
EF-G/eEF-2 domains III and V | 0 | DIRECT |
Flavivirus capsid protein C | 0 | DIRECT |
HMA, heavy metal-associated domain | 0 | DIRECT |
Elongation factors | 0 | DIRECT |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | DIRECT |
Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
HisE-like (PRA-PH) | 0 | DIRECT |
Extended AAA-ATPase domain | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
Ppx/GppA phosphatase | 0 | DIRECT |
ITPase (Ham1) | 0 | DIRECT |
Helicase DNA-binding domain | 0 | DIRECT |
Sec63 C-terminal domain-like | 0 | DIRECT |
Macro domain | 0 | DIRECT |
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | DIRECT |
Caliciviridae-like VP | 0 | DIRECT |
GUCT domain | 0 | DIRECT |
ADPRibase-Mn-like | 0 | DIRECT |
Rap30/74 interaction domains | 0 | DIRECT |
RecG "wedge" domain | 0 | DIRECT |
Ku80 subunit middle domain | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
CDH-like | 0 | DIRECT |
BRK domain-like | 0 | DIRECT |
Viral cysteine protease of trypsin fold | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
mRNA cap methylase | 0 | DIRECT |
N-terminal domain of DnaB helicase | 0 | DIRECT |
Ku70 subunit N-terminal domain | 0 | DIRECT |
Cdc48 N-terminal domain-like | 0 | DIRECT |
Viral proteases | 6.929e-16 | DIRECT |
Tudor domain | 0.0000000000002646 | DIRECT |
HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0.0000000000008982 | DIRECT |
SPRY domain | 0.000000000009168 | DIRECT |
SAP domain | 0.00000000001616 | DIRECT |
Viral glycoprotein, central and dimerisation domains | 0.0000000002469 | DIRECT |
Class II viral fusion proteins C-terminal domain | 0.000000000571 | DIRECT |
Intein (protein splicing domain) | 0.00000002192 | DIRECT |
CYTH domain | 0.00000006285 | DIRECT |
Prokaryotic type I DNA topoisomerase | 0.000004434 | DIRECT |
Coronavirus NSP8-like | 0.00001669 | DIRECT |
Replicase NSP9 | 0.00001669 | DIRECT |
Coronavirus NSP7-like | 0.00001669 | DIRECT |
Coronavirus NSP10-like | 0.00001669 | DIRECT |
AlkB-like | 0.000136 | DIRECT |
Somatomedin B domain | 0.0009325 | DIRECT |
NSP3A-like | 0.0009445 | DIRECT |
WW domain | 0.002948 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
R3H domain | 0.02634 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
PHD domain | 0.07112 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an |
NagD-like | 0.1312 | INHERITED FROM: In phosphorous-containing anhydrides || Inorganic diphosphatase |
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0.1653 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorous-containing anhydrides |
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.1653 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorous-containing anhydrides |
Protein serine/threonine phosphatase | 0.2849 | INHERITED FROM: In phosphorous-containing anhydrides || Bis(5'-nucleosyl)-tetraphosphatase (asymmetrical) || Bis(5'-nucleosyl)-tetraphosphatase (symmetrical) |
Ankyrin repeat | 0.3544 | INHERITED FROM: NAD(+) diphosphatase || In phosphorous-containing anhydrides |
Pleckstrin-homology domain (PH domain) | 0.4013 | INHERITED FROM: Dynamin GTPase || Acting on GTP; involved in cellular and subcellula |
beta-Phosphoglucomutase-like | 0.9857 | INHERITED FROM: In phosphorous-containing anhydrides || Inorganic diphosphatase |
Retrovirus zinc finger-like domains | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
N-terminal Zn binding domain of HIV integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
SurE-like | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Exopolyphosphatase |
Retroviral protease (retropepsin) | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
Reverse transcriptase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
L-histidinol dehydrogenase HisD | 1 | INHERITED FROM: Phosphoribosyl-ATP diphosphatase |
Nitrogenase iron protein-like | 1 | INHERITED FROM: Arsenite-transporting ATPase |
Retroviral integrase, catalytic domain | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
Ribonuclease Rh-like | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
DNA-binding domain of retroviral integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
HisI-like | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Phosphoribosyl-ATP diphosphatase |
SCOP term |
FDR (all) |
Annotation (direct or inherited) |
Nsp15 C-terminal domain-like | 0 | Direct |
Manganese-dependent inorganic pyrophosphatase (family II) | 0 | Direct |
DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
ABC transporter transmembrane region | 0 | Direct |
MutT-like | 0 | Direct |
NADH pyrophosphatase | 0 | Direct |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
Meta-cation ATPase, catalytic domain P | 0 | Direct |
DNA helicase RuvA subunit, N-terminal domain | 0 | Direct |
Inorganic pyrophosphatase | 0 | Direct |
G proteins | 0 | Direct |
ABC transporter ATPase domain-like | 0 | Direct |
Replication initiation protein E1 | 0 | Direct |
ABC-transporter additional domain | 0 | Direct |
RNA helicase | 0 | Direct |
dUTPase-like | 0 | Direct |
Chromo domain | 0 | Direct |
Acylphosphatase-like | 0 | Direct |
DNA-binding domain from rap30 | 0 | Direct |
Helicase-like "domain" of reverse gyrase | 0 | Direct |
Sec63 N-terminal domain | 0 | Direct |
RecA protein-like (ATPase-domain) | 0 | Direct |
C-terminal domain of Ku80 | 0 | Direct |
Tandem AAA-ATPase domain | 0 | Direct |
Ku70 subunit middle domain | 0 | Direct |
DNA helicase RuvA subunit, middle domain | 0 | Direct |
Ku80 subunit N-terminal domain | 0 | Direct |
Nsp15 N-terminal domain-like | 0 | Direct |
HRDC domain from helicases | 0 | Direct |
Ppx associated domain | 0 | Direct |
RecQ helicase DNA-binding domain-like | 0 | Direct |
RNA-dependent RNA-polymerase | 0 | Direct |
Picornaviridae-like VP (VP1, VP2, VP3 and VP4) | 0 | Direct |
EF-G/eEF-2 domains III and V | 0 | Direct |
Flavivirus capsid protein C | 0 | Direct |
HMA, heavy metal-associated domain | 0 | Direct |
Elongation factors | 0 | Direct |
DNA replication initiator (cdc21/cdc54) N-terminal domain | 0 | Direct |
Soluble domain of poliovirus core protein 3a | 0 | Direct |
HisE-like (PRA-PH) | 0 | Direct |
Extended AAA-ATPase domain | 0 | Direct |
Calcium ATPase, transduction domain A | 0 | Direct |
Ppx/GppA phosphatase | 0 | Direct |
ITPase (Ham1) | 0 | Direct |
Helicase DNA-binding domain | 0 | Direct |
Sec63 C-terminal domain-like | 0 | Direct |
Macro domain | 0 | Direct |
Exodeoxyribonuclease V beta chain (RecB), C-terminal domain | 0 | Direct |
Caliciviridae-like VP | 0 | Direct |
GUCT domain | 0 | Direct |
ADPRibase-Mn-like | 0 | Direct |
Rap30/74 interaction domains | 0 | Direct |
RecG "wedge" domain | 0 | Direct |
Ku80 subunit middle domain | 0 | Direct |
Cdc48 domain 2-like | 0 | Direct |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
CDH-like | 0 | Direct |
BRK domain-like | 0 | Direct |
Viral cysteine protease of trypsin fold | 0 | Direct |
Calcium ATPase, transmembrane domain M | 0 | Direct |
mRNA cap methylase | 0 | Direct |
N-terminal domain of DnaB helicase | 0 | Direct |
Ku70 subunit N-terminal domain | 0 | Direct |
Cdc48 N-terminal domain-like | 0 | Direct |
Viral proteases | 6.929e-16 | Direct |
Tudor domain | 0.0000000000002646 | Direct |
HIT (HINT, histidine triad) family of protein kinase-interacting proteins | 0.0000000000008982 | Direct |
SPRY domain | 0.000000000009168 | Direct |
SAP domain | 0.00000000001616 | Direct |
Viral glycoprotein, central and dimerisation domains | 0.0000000002469 | Direct |
Class II viral fusion proteins C-terminal domain | 0.000000000571 | Direct |
Intein (protein splicing domain) | 0.00000002192 | Direct |
CYTH domain | 0.00000006285 | Direct |
Prokaryotic type I DNA topoisomerase | 0.000004434 | Direct |
Coronavirus NSP8-like | 0.00001669 | Direct |
Replicase NSP9 | 0.00001669 | Direct |
Coronavirus NSP7-like | 0.00001669 | Direct |
Coronavirus NSP10-like | 0.00001669 | Direct |
AlkB-like | 0.000136 | Direct |
Somatomedin B domain | 0.0009325 | Direct |
NSP3A-like | 0.0009445 | Direct |
WW domain | 0.002948 | Inherited |
R3H domain | 0.02634 | Inherited |
PHD domain | 0.07112 | Inherited |
NagD-like | 0.1312 | Inherited |
5'-nucleotidase (syn. UDP-sugar hydrolase), N-terminal domain | 0.1653 | Inherited |
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.1653 | Inherited |
Protein serine/threonine phosphatase | 0.2849 | Inherited |
Ankyrin repeat | 0.3544 | Inherited |
Pleckstrin-homology domain (PH domain) | 0.4013 | Inherited |
beta-Phosphoglucomutase-like | 0.9857 | Inherited |
Retrovirus zinc finger-like domains | 1 | Inherited |
N-terminal Zn binding domain of HIV integrase | 1 | Inherited |
SurE-like | 1 | Inherited |
Retroviral protease (retropepsin) | 1 | Inherited |
Reverse transcriptase | 1 | Inherited |
L-histidinol dehydrogenase HisD | 1 | Inherited |
Nitrogenase iron protein-like | 1 | Inherited |
Retroviral integrase, catalytic domain | 1 | Inherited |
Ribonuclease Rh-like | 1 | Inherited |
DNA-binding domain of retroviral integrase | 1 | Inherited |
HisI-like | 1 | Inherited |
Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Trees by TreeVector
A presence/absence matrix is generated using protein domains and supradomains
for all genomes in SUPERFAMILY. The RAxML
software is used to produce a single, large tree topology using
heuristic parsimony methods. Genome combinations, or specific clades, can be displayed as
if individual trees had been produced. However, this data is extracted from the single
large tree. This produces a higher quality topology than if the trees had been produced
on their own, and allows the trees to be displayed instantly.
Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]
Supra-domain (including individual superfamily)
(show details)
Supra-domains annotated to this EC term (SPEO level: Least Informative)
Highlighted in gray are those with FDR>0.001
Supra-domain (Single) |
FDR (all) |
Annotation (direct or inherited) |
mRNA decapping enzyme DcpS N-terminal domain | 0 | DIRECT |
Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
dUTPase-like | 0 | DIRECT |
AN1-like Zinc finger | 0 | DIRECT |
DHH phosphoesterases | 0 | DIRECT |
Nudix | 0 | DIRECT |
Dcp2 domain-like | 0 | DIRECT |
Apyrase | 0 | DIRECT |
C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Origin of replication-binding domain, RBD-like | 0 | DIRECT |
HMA, heavy metal-associated domain | 0 | DIRECT |
Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
all-alpha NTP pyrophosphatases | 0 | DIRECT |
MOP-like | 0 | DIRECT |
Nucleic acid-binding proteins | 0 | DIRECT |
C-terminal domain of Ku80 | 0 | DIRECT |
ABC transporter transmembrane region | 0 | DIRECT |
DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
Restriction endonuclease-like | 0 | DIRECT |
Sec63 N-terminal domain-like | 0 | DIRECT |
EF-G C-terminal domain-like | 0 | DIRECT |
Translation proteins | 0 | DIRECT |
Positive stranded ssRNA viruses | 0 | DIRECT |
Flavivirus capsid protein C | 0 | DIRECT |
Metallo-dependent phosphatases | 0 | DIRECT |
RuvA domain 2-like | 0 | DIRECT |
Calcium ATPase, transduction domain A | 0 | DIRECT |
P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
Inorganic pyrophosphatase | 0 | DIRECT |
ITPase-like | 0 | DIRECT |
N-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
Acylphosphatase/BLUF domain-like | 0 | DIRECT |
EndoU-like | 0 | DIRECT |
Calcium ATPase, transmembrane domain M | 0 | DIRECT |
BRK domain-like | 0 | DIRECT |
DNA primase core | 0 | DIRECT |
SPOC domain-like | 0 | DIRECT |
Cdc48 domain 2-like | 0 | DIRECT |
Rap30/74 interaction domains | 0 | DIRECT |
HIT-like | 0 | DIRECT |
Viral leader polypeptide zinc finger | 0 | DIRECT |
N-terminal domain of DnaB helicase | 0 | DIRECT |
"Winged helix" DNA-binding domain | 0 | DIRECT |
DNA/RNA polymerases | 0 | DIRECT |
HAD-like | 1.756e-16 | DIRECT |
Tudor/PWWP/MBT | 0.0000000000006668 | DIRECT |
Chromo domain-like | 0.00000000000127 | DIRECT |
SAP domain | 0.00000000001719 | DIRECT |
Hedgehog/intein (Hint) domain | 0.00000000001938 | DIRECT |
Viral glycoprotein, central and dimerisation domains | 0.0000000003811 | DIRECT |
vWA-like | 0.0000000008602 | DIRECT |
Homing endonucleases | 0.000000002878 | DIRECT |
Prokaryotic type I DNA topoisomerase | 0.000004814 | DIRECT |
Coronavirus NSP8-like | 0.00002163 | DIRECT |
Replicase NSP9 | 0.00002163 | DIRECT |
Coronavirus NSP10-like | 0.00002163 | DIRECT |
Coronavirus NSP7-like | 0.00002163 | DIRECT |
MIT domain | 0.00002609 | DIRECT |
E set domains | 0.0002513 | DIRECT |
HRDC-like | 0.0004501 | DIRECT |
Somatomedin B domain | 0.001043 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
NSP3A-like | 0.001129 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an || RNA helicase |
WW domain | 0.003084 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
beta-sandwich domain of Sec23/24 | 0.006891 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an |
Bromodomain | 0.007183 | INHERITED FROM: Adenosinetriphosphatase |
FYVE/PHD zinc finger | 0.007211 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an |
RNA-binding domain, RBD | 0.009769 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
His-Me finger endonucleases | 0.01717 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
R3H domain | 0.0286 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
SARS Nsp1-like | 0.0477 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an || RNA helicase |
5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.1776 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorous-containing anhydrides || Apyrase |
Trypsin-like serine proteases | 0.2448 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
CBS-domain pair | 0.4101 | INHERITED FROM: Quaternary-amine-transporting ATPase |
Ankyrin repeat | 0.4234 | INHERITED FROM: NAD(+) diphosphatase |
NTF2-like | 0.5131 | INHERITED FROM: RNA helicase |
CYTH-like phosphatases | 0.5978 | INHERITED FROM: In phosphorous-containing anhydrides || Thiamine-triphosphatase |
HD-domain/PDEase-like | 0.7324 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha |
Clavaminate synthase-like | 0.8109 | INHERITED FROM: RNA helicase |
UBA-like | 0.904 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an |
Acid phosphatase/Vanadium-dependent haloperoxidase | 0.9753 | INHERITED FROM: Undecaprenyl-diphosphatase || In phosphorous-containing anhydrides || Dolichyldiphosphatase |
PH domain-like | 1 | INHERITED FROM: Dynamin GTPase || Acting on GTP; involved in cellular and subcellula |
N-terminal Zn binding domain of HIV integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
ADC-like | 1 | INHERITED FROM: Vesicle-fusing ATPase |
Acid proteases | 1 | INHERITED FROM: dUTP diphosphatase |
Retrovirus zinc finger-like domains | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
Actin-like ATPase domain | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha || Exopolyphosphatase |
Alkaline phosphatase-like | 1 | INHERITED FROM: Nucleotide diphosphatase |
S-adenosyl-L-methionine-dependent methyltransferases | 1 | INHERITED FROM: Nucleoside-triphosphatase || RNA helicase |
HisI-like | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Phosphoribosyl-ATP diphosphatase |
DNA-binding domain of retroviral integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
Concanavalin A-like lectins/glucanases | 1 | INHERITED FROM: RNA helicase |
Ribonuclease Rh-like | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
Macro domain-like | 1 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || Nucleoside-triphosphatase || RNA helicase || In phosphorous-containing anhydrides |
SurE-like | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Exopolyphosphatase |
(show details)
Supra-domains annotated to this EC term (SPEO level: Least Informative)
Highlighted in gray are those with FDR>0.001
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
50615,52540 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
100939,68906 100939 - SPOC domain-like 68906 - SAP domain | 0 | DIRECT |
56672,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
101386,53720 101386 - all-alpha NTP pyrophosphatases 53720 - ALDH-like | 0 | DIRECT |
52540,54928 52540 - P-loop containing nucleoside triphosphate hydrolases 54928 - RNA-binding domain, RBD | 0 | DIRECT |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | DIRECT |
50249,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
53335,52949 53335 - S-adenosyl-L-methionine-dependent methyltransferases 52949 - Macro domain-like | 0 | DIRECT |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
160481,160481 160481 - BRK domain-like 160481 - BRK domain-like | 0 | DIRECT |
158702,81296 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | DIRECT |
51283,51283 51283 - dUTPase-like 51283 - dUTPase-like | 0 | DIRECT |
53067,109604 53067 - Actin-like ATPase domain 109604 - HD-domain/PDEase-like | 0 | DIRECT |
81653,81665 81653 - Calcium ATPase, transduction domain A 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | DIRECT |
50916,46785 50916 - Rap30/74 interaction domains 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50494,56672 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases | 0 | DIRECT |
52540,47370 52540 - P-loop containing nucleoside triphosphate hydrolases 47370 - Bromodomain | 0 | DIRECT |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
52540,57756 52540 - P-loop containing nucleoside triphosphate hydrolases 57756 - Retrovirus zinc finger-like domains | 0 | DIRECT |
55811,55811 55811 - Nudix 55811 - Nudix | 0 | DIRECT |
52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
56672,88633 56672 - DNA/RNA polymerases 88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | DIRECT |
100939,101420 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | DIRECT |
52540,89043 52540 - P-loop containing nucleoside triphosphate hydrolases 89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
46785,47819 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | DIRECT |
56731,52540 56731 - DNA primase core 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
46785,158702 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
55608,52540 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
49899,52540 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
158702,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
48024,52540 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
140586,55811 140586 - Dcp2 domain-like 55811 - Nudix | 0 | DIRECT |
101386,101386 101386 - all-alpha NTP pyrophosphatases 101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
81665,81660 81665 - Calcium ATPase, transmembrane domain M 81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | DIRECT |
53335,56672 53335 - S-adenosyl-L-methionine-dependent methyltransferases 56672 - DNA/RNA polymerases | 0 | DIRECT |
89043,50494 89043 - Soluble domain of poliovirus core protein 3a 50494 - Trypsin-like serine proteases | 0 | DIRECT |
47781,46929 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
51294,52540 51294 - Hedgehog/intein (Hint) domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,100939 53300 - vWA-like 100939 - SPOC domain-like | 0 | DIRECT |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50494,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88633,50494 88633 - Positive stranded ssRNA viruses 50494 - Trypsin-like serine proteases | 0 | DIRECT |
102860,54197 102860 - mRNA decapping enzyme DcpS N-terminal domain 54197 - HIT-like | 0 | DIRECT |
53335,142877 53335 - S-adenosyl-L-methionine-dependent methyltransferases 142877 - EndoU-like | 0 | DIRECT |
50331,50331 50331 - MOP-like 50331 - MOP-like | 0 | DIRECT |
52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | DIRECT |
54980,54980 54980 - EF-G C-terminal domain-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
55464,52540 55464 - Origin of replication-binding domain, RBD-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,50331 52540 - P-loop containing nucleoside triphosphate hydrolases 50331 - MOP-like | 0 | DIRECT |
50249,47781 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like | 0 | DIRECT |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
81665,56784 81665 - Calcium ATPase, transmembrane domain M 56784 - HAD-like | 0 | DIRECT |
52540,49899 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases | 0 | DIRECT |
52540,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
55608,56712 55608 - Homing endonucleases 56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | DIRECT |
52980,47781 52980 - Restriction endonuclease-like 47781 - RuvA domain 2-like | 0 | DIRECT |
141734,101386 141734 - HisI-like 101386 - all-alpha NTP pyrophosphatases | 0 | DIRECT |
52540,54631 52540 - P-loop containing nucleoside triphosphate hydrolases 54631 - CBS-domain pair | 0 | DIRECT |
55008,55008 55008 - HMA, heavy metal-associated domain 55008 - HMA, heavy metal-associated domain | 0 | DIRECT |
88633,88633 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses | 0.0000000000007057 | DIRECT |
51294,55608 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0.000000000001331 | DIRECT |
56983,81296 56983 - Viral glycoprotein, central and dimerisation domains 81296 - E set domains | 0.0000000008725 | DIRECT |
51197,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000000002093 | DIRECT |
56712,51294 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0.00001708 | DIRECT |
140367,143076 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like | 0.00002163 | DIRECT |
101816,144246 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0.00002163 | DIRECT |
143076,101816 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0.00002163 | DIRECT |
53649,54060 53649 - Alkaline phosphatase-like 54060 - His-Me finger endonucleases | 0.0000863 | DIRECT |
51283,46919 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase | 0.001043 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
53098,51283 53098 - Ribonuclease H-like 51283 - dUTPase-like | 0.001043 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
90188,53649 90188 - Somatomedin B domain 53649 - Alkaline phosphatase-like | 0.001043 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
90188,90188 90188 - Somatomedin B domain 90188 - Somatomedin B domain | 0.001043 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
54001,88633 54001 - Cysteine proteinases 88633 - Positive stranded ssRNA viruses | 0.001923 | INHERITED FROM: Nucleoside-triphosphatase || In phosphorous-containing anhydrides |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0.02637 | INHERITED FROM: Acting on acid anhydrides; involved in cellular an || RNA helicase |
159936,52949 159936 - NSP3A-like 52949 - Macro domain-like | 0.0477 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an || RNA helicase |
159936,53335 159936 - NSP3A-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.06124 | INHERITED FROM: DNA helicase || Acting on acid anhydrides; involved in cellular an || RNA helicase |
56300,55816 56300 - Metallo-dependent phosphatases 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.1776 | INHERITED FROM: UDP-sugar diphosphatase || In phosphorous-containing anhydrides || Apyrase |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 1 | INHERITED FROM: In phosphorous-containing anhydrides || Guanosine-5'-triphosphate,3'-diphosphate diphospha || Exopolyphosphatase |
46919,53098 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
56672,53098 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
50630,56672 50630 - Acid proteases 56672 - DNA/RNA polymerases | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
53098,50122 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
Supra-domain (Duplex) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
50447,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | Direct |
50615,52540 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
100939,68906 100939 - SPOC domain-like 68906 - SAP domain | 0 | Direct |
56672,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
101386,53720 101386 - all-alpha NTP pyrophosphatases 53720 - ALDH-like | 0 | Direct |
52540,54928 52540 - P-loop containing nucleoside triphosphate hydrolases 54928 - RNA-binding domain, RBD | 0 | Direct |
50692,54585 50692 - ADC-like 54585 - Cdc48 domain 2-like | 0 | Direct |
50249,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
53335,52949 53335 - S-adenosyl-L-methionine-dependent methyltransferases 52949 - Macro domain-like | 0 | Direct |
52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
160481,160481 160481 - BRK domain-like 160481 - BRK domain-like | 0 | Direct |
158702,81296 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | Direct |
51283,51283 51283 - dUTPase-like 51283 - dUTPase-like | 0 | Direct |
53067,109604 53067 - Actin-like ATPase domain 109604 - HD-domain/PDEase-like | 0 | Direct |
81653,81665 81653 - Calcium ATPase, transduction domain A 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
52540,50447 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins | 0 | Direct |
50916,46785 50916 - Rap30/74 interaction domains 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50494,56672 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases | 0 | Direct |
52540,47370 52540 - P-loop containing nucleoside triphosphate hydrolases 47370 - Bromodomain | 0 | Direct |
52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
81660,56784 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
52540,57756 52540 - P-loop containing nucleoside triphosphate hydrolases 57756 - Retrovirus zinc finger-like domains | 0 | Direct |
55811,55811 55811 - Nudix 55811 - Nudix | 0 | Direct |
52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
56672,88633 56672 - DNA/RNA polymerases 88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | Direct |
100939,101420 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | Direct |
52540,89043 52540 - P-loop containing nucleoside triphosphate hydrolases 89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
46785,47819 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | Direct |
56731,52540 56731 - DNA primase core 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
46785,158702 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | Direct |
55608,52540 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
49899,52540 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
158702,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
48024,52540 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
140586,55811 140586 - Dcp2 domain-like 55811 - Nudix | 0 | Direct |
101386,101386 101386 - all-alpha NTP pyrophosphatases 101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
81665,81660 81665 - Calcium ATPase, transmembrane domain M 81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
90123,52540 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | Direct |
53335,56672 53335 - S-adenosyl-L-methionine-dependent methyltransferases 56672 - DNA/RNA polymerases | 0 | Direct |
89043,50494 89043 - Soluble domain of poliovirus core protein 3a 50494 - Trypsin-like serine proteases | 0 | Direct |
47781,46929 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
51294,52540 51294 - Hedgehog/intein (Hint) domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,90123 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
54160,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,100939 53300 - vWA-like 100939 - SPOC domain-like | 0 | Direct |
54585,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50494,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88633,50494 88633 - Positive stranded ssRNA viruses 50494 - Trypsin-like serine proteases | 0 | Direct |
102860,54197 102860 - mRNA decapping enzyme DcpS N-terminal domain 54197 - HIT-like | 0 | Direct |
53335,142877 53335 - S-adenosyl-L-methionine-dependent methyltransferases 142877 - EndoU-like | 0 | Direct |
50331,50331 50331 - MOP-like 50331 - MOP-like | 0 | Direct |
52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | Direct |
54980,54980 54980 - EF-G C-terminal domain-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
55464,52540 55464 - Origin of replication-binding domain, RBD-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,50331 52540 - P-loop containing nucleoside triphosphate hydrolases 50331 - MOP-like | 0 | Direct |
50249,47781 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like | 0 | Direct |
56784,81665 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
81665,56784 81665 - Calcium ATPase, transmembrane domain M 56784 - HAD-like | 0 | Direct |
52540,49899 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases | 0 | Direct |
52540,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 54980 - EF-G C-terminal domain-like | 0 | Direct |
55608,56712 55608 - Homing endonucleases 56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
52540,47917 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
54160,54160 54160 - Chromo domain-like 54160 - Chromo domain-like | 0 | Direct |
52980,47781 52980 - Restriction endonuclease-like 47781 - RuvA domain 2-like | 0 | Direct |
141734,101386 141734 - HisI-like 101386 - all-alpha NTP pyrophosphatases | 0 | Direct |
52540,54631 52540 - P-loop containing nucleoside triphosphate hydrolases 54631 - CBS-domain pair | 0 | Direct |
55008,55008 55008 - HMA, heavy metal-associated domain 55008 - HMA, heavy metal-associated domain | 0 | Direct |
88633,88633 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses | 0.0000000000007057 | Direct |
51294,55608 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0.000000000001331 | Direct |
56983,81296 56983 - Viral glycoprotein, central and dimerisation domains 81296 - E set domains | 0.0000000008725 | Direct |
51197,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0.000000002093 | Direct |
56712,51294 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0.00001708 | Direct |
140367,143076 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like | 0.00002163 | Direct |
101816,144246 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0.00002163 | Direct |
143076,101816 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0.00002163 | Direct |
53649,54060 53649 - Alkaline phosphatase-like 54060 - His-Me finger endonucleases | 0.0000863 | Direct |
51283,46919 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase | 0.001043 | Inherited |
53098,51283 53098 - Ribonuclease H-like 51283 - dUTPase-like | 0.001043 | Inherited |
90188,53649 90188 - Somatomedin B domain 53649 - Alkaline phosphatase-like | 0.001043 | Inherited |
90188,90188 90188 - Somatomedin B domain 90188 - Somatomedin B domain | 0.001043 | Inherited |
54001,88633 54001 - Cysteine proteinases 88633 - Positive stranded ssRNA viruses | 0.001923 | Inherited |
57756,57756 57756 - Retrovirus zinc finger-like domains 57756 - Retrovirus zinc finger-like domains | 0.02637 | Inherited |
159936,52949 159936 - NSP3A-like 52949 - Macro domain-like | 0.0477 | Inherited |
159936,53335 159936 - NSP3A-like 53335 - S-adenosyl-L-methionine-dependent methyltransferases | 0.06124 | Inherited |
56300,55816 56300 - Metallo-dependent phosphatases 55816 - 5'-nucleotidase (syn. UDP-sugar hydrolase), C-terminal domain | 0.1776 | Inherited |
53067,53067 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain | 1 | Inherited |
46919,53098 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like | 1 | Inherited |
56672,53098 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like | 1 | Inherited |
50630,56672 50630 - Acid proteases 56672 - DNA/RNA polymerases | 1 | Inherited |
53098,50122 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase | 1 | Inherited |
(show details)
Supra-domains annotated to this EC term (SPEO level: Least Informative)
Highlighted in gray are those with FDR>0.001
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
89043,50494,56672 89043 - Soluble domain of poliovirus core protein 3a 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases | 0 | DIRECT |
50249,52540,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,46785,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | DIRECT |
50494,52540,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | DIRECT |
46785,158702,52540 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53067,53067,109604 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 109604 - HD-domain/PDEase-like | 0 | DIRECT |
50494,52540,89043 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 89043 - Soluble domain of poliovirus core protein 3a | 0 | DIRECT |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
51294,55608,52540 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50447,54980,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
51197,52540,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,49899,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
53300,100939,101420 53300 - vWA-like 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | DIRECT |
52540,50447,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
52540,51294,55608 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0 | DIRECT |
51197,52540,56672 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | DIRECT |
52540,56712,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,54980,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 54980 - EF-G C-terminal domain-like 54980 - EF-G C-terminal domain-like | 0 | DIRECT |
55608,52540,47917 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | DIRECT |
81653,81665,56784 81653 - Calcium ATPase, transduction domain A 81665 - Calcium ATPase, transmembrane domain M 56784 - HAD-like | 0 | DIRECT |
48024,52540,51294 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 0 | DIRECT |
81653,81665,81660 81653 - Calcium ATPase, transduction domain A 81665 - Calcium ATPase, transmembrane domain M 81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | DIRECT |
46785,158702,81296 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | DIRECT |
56672,52540,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | DIRECT |
50494,56672,88633 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases 88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
55008,55008,55008 55008 - HMA, heavy metal-associated domain 55008 - HMA, heavy metal-associated domain 55008 - HMA, heavy metal-associated domain | 0 | DIRECT |
158702,52540,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
88633,88633,88633 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses | 0 | DIRECT |
52540,52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | DIRECT |
52540,89043,50494 52540 - P-loop containing nucleoside triphosphate hydrolases 89043 - Soluble domain of poliovirus core protein 3a 50494 - Trypsin-like serine proteases | 0 | DIRECT |
52540,46785,158702 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | DIRECT |
50615,52540,47917 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | DIRECT |
52540,52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | DIRECT |
52540,52540,47370 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 47370 - Bromodomain | 0 | DIRECT |
50494,52540,56672 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | DIRECT |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
141734,101386,53720 141734 - HisI-like 101386 - all-alpha NTP pyrophosphatases 53720 - ALDH-like | 0 | DIRECT |
81665,81660,56784 81665 - Calcium ATPase, transmembrane domain M 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | DIRECT |
50249,47781,46929 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | DIRECT |
88633,50494,52540 88633 - Positive stranded ssRNA viruses 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,50331,50331 52540 - P-loop containing nucleoside triphosphate hydrolases 50331 - MOP-like 50331 - MOP-like | 0 | DIRECT |
53300,100939,68906 53300 - vWA-like 100939 - SPOC domain-like 68906 - SAP domain | 0 | DIRECT |
52540,51294,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | DIRECT |
52540,52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | DIRECT |
52540,52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0.000000000000002433 | DIRECT |
140367,143076,101816 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0.00002163 | DIRECT |
143076,101816,144246 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0.00002163 | DIRECT |
90188,53649,54060 90188 - Somatomedin B domain 53649 - Alkaline phosphatase-like 54060 - His-Me finger endonucleases | 0.0000863 | DIRECT |
53098,51283,46919 53098 - Ribonuclease H-like 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase | 0.001043 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
56672,53098,51283 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like 51283 - dUTPase-like | 0.001043 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
90188,90188,53649 90188 - Somatomedin B domain 90188 - Somatomedin B domain 53649 - Alkaline phosphatase-like | 0.001043 | INHERITED FROM: Nucleotide diphosphatase || In phosphorous-containing anhydrides |
51283,46919,53098 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like | 0.001043 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
54001,88633,88633 54001 - Cysteine proteinases 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses | 0.001923 | INHERITED FROM: Nucleoside-triphosphatase || In phosphorous-containing anhydrides |
46919,53098,50122 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
50630,56672,53098 50630 - Acid proteases 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like | 1 | INHERITED FROM: dUTP diphosphatase || In phosphorous-containing anhydrides |
Supra-domain (Triple) in N- to C-terminal order |
FDR (all) |
Annotation (direct or inherited) |
89043,50494,56672 89043 - Soluble domain of poliovirus core protein 3a 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases | 0 | Direct |
50249,52540,52540 50249 - Nucleic acid-binding proteins 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,46785,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 47819 - HRDC-like | 0 | Direct |
50494,52540,52540 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
90123,52540,90123 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region | 0 | Direct |
46785,158702,52540 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53067,53067,109604 53067 - Actin-like ATPase domain 53067 - Actin-like ATPase domain 109604 - HD-domain/PDEase-like | 0 | Direct |
50494,52540,89043 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 89043 - Soluble domain of poliovirus core protein 3a | 0 | Direct |
52540,52540,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
51294,55608,52540 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,90123,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 90123 - ABC transporter transmembrane region 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50447,54980,54980 50447 - Translation proteins 54980 - EF-G C-terminal domain-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
51197,52540,52540 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,49899,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 49899 - Concanavalin A-like lectins/glucanases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
53300,100939,101420 53300 - vWA-like 100939 - SPOC domain-like 101420 - C-terminal domain of Ku80 | 0 | Direct |
52540,50447,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 50447 - Translation proteins 54980 - EF-G C-terminal domain-like | 0 | Direct |
52540,51294,55608 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain 55608 - Homing endonucleases | 0 | Direct |
51197,52540,56672 51197 - Clavaminate synthase-like 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | Direct |
52540,56712,51294 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
54160,54160,52540 54160 - Chromo domain-like 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,54980,54980 52540 - P-loop containing nucleoside triphosphate hydrolases 54980 - EF-G C-terminal domain-like 54980 - EF-G C-terminal domain-like | 0 | Direct |
55608,52540,47917 55608 - Homing endonucleases 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
81660,56784,81665 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like 81665 - Calcium ATPase, transmembrane domain M | 0 | Direct |
81653,81665,56784 81653 - Calcium ATPase, transduction domain A 81665 - Calcium ATPase, transmembrane domain M 56784 - HAD-like | 0 | Direct |
48024,52540,51294 48024 - N-terminal domain of DnaB helicase 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain | 0 | Direct |
81653,81665,81660 81653 - Calcium ATPase, transduction domain A 81665 - Calcium ATPase, transmembrane domain M 81660 - Metal cation-transporting ATPase, ATP-binding domain N | 0 | Direct |
46785,158702,81296 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like 81296 - E set domains | 0 | Direct |
56672,52540,52540 56672 - DNA/RNA polymerases 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
50692,54585,52540 50692 - ADC-like 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
54585,52540,52540 54585 - Cdc48 domain 2-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540,46785 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain | 0 | Direct |
50494,56672,88633 50494 - Trypsin-like serine proteases 56672 - DNA/RNA polymerases 88633 - Positive stranded ssRNA viruses | 0 | Direct |
55008,55008,55008 55008 - HMA, heavy metal-associated domain 55008 - HMA, heavy metal-associated domain 55008 - HMA, heavy metal-associated domain | 0 | Direct |
158702,52540,52540 158702 - Sec63 N-terminal domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
88633,88633,88633 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses | 0 | Direct |
52540,52540,142877 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 142877 - EndoU-like | 0 | Direct |
52540,89043,50494 52540 - P-loop containing nucleoside triphosphate hydrolases 89043 - Soluble domain of poliovirus core protein 3a 50494 - Trypsin-like serine proteases | 0 | Direct |
52540,46785,158702 52540 - P-loop containing nucleoside triphosphate hydrolases 46785 - "Winged helix" DNA-binding domain 158702 - Sec63 N-terminal domain-like | 0 | Direct |
50615,52540,47917 50615 - N-terminal domain of alpha and beta subunits of F1 ATP synthase 52540 - P-loop containing nucleoside triphosphate hydrolases 47917 - C-terminal domain of alpha and beta subunits of F1 ATP synthase | 0 | Direct |
52540,52540,47819 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 47819 - HRDC-like | 0 | Direct |
52540,52540,47370 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 47370 - Bromodomain | 0 | Direct |
50494,52540,56672 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0 | Direct |
54160,52540,52540 54160 - Chromo domain-like 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
141734,101386,53720 141734 - HisI-like 101386 - all-alpha NTP pyrophosphatases 53720 - ALDH-like | 0 | Direct |
81665,81660,56784 81665 - Calcium ATPase, transmembrane domain M 81660 - Metal cation-transporting ATPase, ATP-binding domain N 56784 - HAD-like | 0 | Direct |
50249,47781,46929 50249 - Nucleic acid-binding proteins 47781 - RuvA domain 2-like 46929 - DNA helicase RuvA subunit, C-terminal domain | 0 | Direct |
88633,50494,52540 88633 - Positive stranded ssRNA viruses 50494 - Trypsin-like serine proteases 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,50331,50331 52540 - P-loop containing nucleoside triphosphate hydrolases 50331 - MOP-like 50331 - MOP-like | 0 | Direct |
53300,100939,68906 53300 - vWA-like 100939 - SPOC domain-like 68906 - SAP domain | 0 | Direct |
52540,51294,52540 52540 - P-loop containing nucleoside triphosphate hydrolases 51294 - Hedgehog/intein (Hint) domain 52540 - P-loop containing nucleoside triphosphate hydrolases | 0 | Direct |
52540,52540,56712 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56712 - Prokaryotic type I DNA topoisomerase | 0 | Direct |
52540,52540,56672 52540 - P-loop containing nucleoside triphosphate hydrolases 52540 - P-loop containing nucleoside triphosphate hydrolases 56672 - DNA/RNA polymerases | 0.000000000000002433 | Direct |
140367,143076,101816 140367 - Coronavirus NSP7-like 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 | 0.00002163 | Direct |
143076,101816,144246 143076 - Coronavirus NSP8-like 101816 - Replicase NSP9 144246 - Coronavirus NSP10-like | 0.00002163 | Direct |
90188,53649,54060 90188 - Somatomedin B domain 53649 - Alkaline phosphatase-like 54060 - His-Me finger endonucleases | 0.0000863 | Direct |
53098,51283,46919 53098 - Ribonuclease H-like 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase | 0.001043 | Inherited |
56672,53098,51283 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like 51283 - dUTPase-like | 0.001043 | Inherited |
90188,90188,53649 90188 - Somatomedin B domain 90188 - Somatomedin B domain 53649 - Alkaline phosphatase-like | 0.001043 | Inherited |
51283,46919,53098 51283 - dUTPase-like 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like | 0.001043 | Inherited |
54001,88633,88633 54001 - Cysteine proteinases 88633 - Positive stranded ssRNA viruses 88633 - Positive stranded ssRNA viruses | 0.001923 | Inherited |
46919,53098,50122 46919 - N-terminal Zn binding domain of HIV integrase 53098 - Ribonuclease H-like 50122 - DNA-binding domain of retroviral integrase | 1 | Inherited |
50630,56672,53098 50630 - Acid proteases 56672 - DNA/RNA polymerases 53098 - Ribonuclease H-like | 1 | Inherited |
Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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A presence/absence matrix is generated using protein domains and supradomains
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