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Carbon--nitrogen ligases with glutamine as amido-N

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Root: EC Hierarchy (from IntEnz release 70)

Shortest distance to current term (+ for parents, - for children) EC term [EC ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   root [root] <6>
+ + 2:   Ligases [6] <6>(80|99) (88|104|66)
+ 1:   Forming carbon-nitrogen bonds [6.3] <5>(45|56) (51|54|37)
0:   Carbon--nitrogen ligases with glutamine as amido-N [6.3.5] <11>(15|14) (15|18|15)
- 1:   Adenosylcobyric acid synthase (glutamine-hydrolyzi [6.3.5.10](0|0) (0|0|0)
- 1:   Asparagine synthase (glutamine-hydrolyzing) [6.3.5.4](2|2) (2|1|0)
- 1:   Asparaginyl-tRNA synthase (glutamine-hydrolyzing) [6.3.5.6](0|0) (0|0|0)
- 1:   Carbamoyl-phosphate synthase (glutamine-hydrolyzin [6.3.5.5](6|6) (6|8|8)
- 1:   Cobyrinate a,c-diamide synthase (glutamine-hydroly [6.3.5.11](0|0) (0|0|0)
- 1:   GMP synthase (glutamine-hydrolyzing) [6.3.5.2](3|3) (3|3|2)
- 1:   Glutaminyl-tRNA synthase (glutamine-hydrolyzing) [6.3.5.7](0|0) (0|0|0)
- 1:   Hydrogenobyrinic acid a,c-diamide synthase (glutam [6.3.5.9](0|0) (0|0|0)
- 1:   NAD(+) synthase (glutamine-hydrolyzing) [6.3.5.1](2|1) (2|1|0)
- 1:   Phosphoribosylformylglycinamidine synthase [6.3.5.3](4|4) (4|5|5)
- 1:   Transferred entry: 2.6.1.85 [6.3.5.8](0|0) (0|0|0)


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Superfamily

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SCOP term FDR (all) Annotation (direct or inherited)
PurM N-terminal domain-like0Direct
Class I glutamine amidotransferase-like0Direct
PurM C-terminal domain-like0Direct
Methylglyoxal synthase-like0Direct
GMP synthetase C-terminal dimerisation domain0Direct
PurS-like0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Carbamoyl phosphate synthetase, large subunit connection domain0Direct
FGAM synthase PurL, linker domain0Direct
Carbon-nitrogen hydrolase0Direct
Carbamoyl phosphate synthetase, small subunit N-terminal domain0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.00000004896Direct
PreATP-grasp domain0.00001332Direct
Glutathione synthetase ATP-binding domain-like0.0001175Direct
Aspartate/ornithine carbamoyltransferase0.5347Inherited


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Family

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SCOP term FDR (all) Annotation (direct or inherited)
PurM C-terminal domain-like0Direct
BC N-terminal domain-like0Direct
GMP synthetase C-terminal dimerisation domain0Direct
N-type ATP pyrophosphatases0Direct
PurM N-terminal domain-like0Direct
BC ATP-binding domain-like0Direct
Class I glutamine amidotransferases (GAT)0Direct
Carbamoyl phosphate synthetase, large subunit connection domain0Direct
FGAM synthase PurL, linker domain0Direct
Carbamoyl phosphate synthetase, small subunit N-terminal domain0Direct
Class II glutamine amidotransferases0Direct
Carbamoyl phosphate synthetase, large subunit allosteric, C-terminal domain0Direct
FGAM synthase PurL, PurS-like domain0Direct
Hydantoinase (dihydropyrimidinase), catalytic domain0.00006531Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this EC term
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Jump to [ Top · EC Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Carbamoyl phosphate synthetase, small subunit N-terminal domain0Direct
PurS-like0Direct
GMP synthetase C-terminal dimerisation domain0Direct
FGAM synthase PurL, linker domain0Direct
PurM C-terminal domain-like0Direct
Carbon-nitrogen hydrolase0Direct
PurM N-terminal domain-like0Direct
Adenine nucleotide alpha hydrolases-like0Direct
Class I glutamine amidotransferase-like0Direct
Carbamoyl phosphate synthetase, large subunit connection domain0Direct
Methylglyoxal synthase-like0Direct
N-terminal nucleophile aminohydrolases (Ntn hydrolases)0.0000000367Direct
PreATP-grasp domain0.00001083Direct
Glutathione synthetase ATP-binding domain-like0.00009716Direct
Aspartate/ornithine carbamoyltransferase0.4953Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
52021,52317
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 0Direct
    52402,54810
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 54810 - GMP synthetase C-terminal dimerisation domain
  • 0Direct
    55326,56042
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0Direct
    109736,55326
  • 109736 - FGAM synthase PurL, linker domain
  • 55326 - PurM N-terminal domain-like
  • 0Direct
    56059,52335
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0Direct
    56235,52402
  • 56235 - N-terminal nucleophile aminohydrolases (Ntn hydrolases)
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0Direct
    56317,52402
  • 56317 - Carbon-nitrogen hydrolase
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0Direct
    56042,52317
  • 56042 - PurM C-terminal domain-like
  • 52317 - Class I glutamine amidotransferase-like
  • 0Direct
    56042,55326
  • 56042 - PurM C-terminal domain-like
  • 55326 - PurM N-terminal domain-like
  • 0Direct
    52335,51556
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    48108,52440
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0Direct
    54810,54810
  • 54810 - GMP synthetase C-terminal dimerisation domain
  • 54810 - GMP synthetase C-terminal dimerisation domain
  • 0Direct
    82697,109736
  • 82697 - PurS-like
  • 109736 - FGAM synthase PurL, linker domain
  • 0Direct
    56059,48108
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0Direct
    52317,52402
  • 52317 - Class I glutamine amidotransferase-like
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 0Direct
    52440,56059
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.000003337Direct
    52317,52440
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.00003176Direct
    51556,51338
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0.1281Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52440,56059,48108
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 0Direct
    48108,52440,56059
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0Direct
    52402,54810,54810
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 54810 - GMP synthetase C-terminal dimerisation domain
  • 54810 - GMP synthetase C-terminal dimerisation domain
  • 0Direct
    56059,48108,52440
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 48108 - Carbamoyl phosphate synthetase, large subunit connection domain
  • 52440 - PreATP-grasp domain
  • 0Direct
    56059,52335,51556
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 0Direct
    55326,56042,52317
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 52317 - Class I glutamine amidotransferase-like
  • 0Direct
    55326,56042,55326
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 55326 - PurM N-terminal domain-like
  • 0Direct
    56042,55326,56042
  • 56042 - PurM C-terminal domain-like
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0Direct
    52335,51556,51338
  • 52335 - Methylglyoxal synthase-like
  • 51556 - Metallo-dependent hydrolases
  • 51338 - Composite domain of metallo-dependent hydrolases
  • 0Direct
    109736,55326,56042
  • 109736 - FGAM synthase PurL, linker domain
  • 55326 - PurM N-terminal domain-like
  • 56042 - PurM C-terminal domain-like
  • 0Direct
    82697,109736,55326
  • 82697 - PurS-like
  • 109736 - FGAM synthase PurL, linker domain
  • 55326 - PurM N-terminal domain-like
  • 0Direct
    52317,52402,54810
  • 52317 - Class I glutamine amidotransferase-like
  • 52402 - Adenine nucleotide alpha hydrolases-like
  • 54810 - GMP synthetase C-terminal dimerisation domain
  • 0Direct
    52440,56059,52335
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 52335 - Methylglyoxal synthase-like
  • 0Direct
    52317,52440,56059
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 0.00003176Direct
    52021,52317,52440
  • 52021 - Carbamoyl phosphate synthetase, small subunit N-terminal domain
  • 52317 - Class I glutamine amidotransferase-like
  • 52440 - PreATP-grasp domain
  • 0.00003176Direct


    Plot distribution on phylogenetic tree for Individual Supra-domains annotated by this EC term
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