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Domain assignment for gi|157389005|ref|NP_001739.2| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|157389005|ref|NP_001739.2|
Domain Number 1 Region: 4-353
Classification Level Classification E-value
Superfamily Cysteine proteinases 9.72e-140
Family Calpain large subunit, catalytic domain (domain II) 0.00000000000226
Further Details:      
 
Domain Number 2 Region: 356-513
Classification Level Classification E-value
Superfamily Calpain large subunit, middle domain (domain III) 3.92e-58
Family Calpain large subunit, middle domain (domain III) 0.0000000193
Further Details:      
 
Domain Number 3 Region: 525-697
Classification Level Classification E-value
Superfamily EF-hand 3.2e-45
Family Penta-EF-hand proteins 0.0000000688
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) gi|157389005|ref|NP_001739.2|
Sequence length 700
Comment calpain-2 catalytic subunit isoform 1 [Homo sapiens]
Sequence
MAGIAAKLAKDREAAEGLGSHERAIKYLNQDYEALRNECLEAGTLFQDPSFPAIPSALGF
KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPLNQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELKKPPPNLFKIIQKALQKGSLLGC
SIDITSAADSEAITFQKLVKGHAYSVTGAEEVESNGSLQKLIRIRNPWGEVEWTGRWNDN
CPSWNTIDPEERERLTRRHEDGEFWMSFSDFLRHYSRLEICNLTPDTLTSDTYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGESGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELSGQTNIHLSKNFFLTNRARERSDTFINLREVLNRFKLPPG
EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDISEDDIDDGFRRLFAQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDSDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQLIIDFD
NFVRCLVRLETLFKIFKQLDPENTGTIELDLISWLCFSVL
Download sequence
Identical sequences A0A2J8U2C5 H2Q170
gi|157389005|ref|NP_001739.2| NP_001739.2.87134 NP_001739.2.92137 XP_003308813.1.37143 ENSPTRP00000003379 ENSPTRP00000003379

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