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Domain assignment for gi|224926826|ref|NP_001139267.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|224926826|ref|NP_001139267.1|
Domain Number 1 Region: 267-381
Classification Level Classification E-value
Superfamily PH domain-like 2.72e-32
Family Pleckstrin-homology domain (PH domain) 0.00008
Further Details:      
 
Domain Number 2 Region: 524-627
Classification Level Classification E-value
Superfamily SH2 domain 5.12e-25
Family SH2 domain 0.0000127
Further Details:      
 
Domain Number 3 Region: 24-83
Classification Level Classification E-value
Superfamily Phenylalanine zipper 6.28e-22
Family Adapter protein APS, dimerisation domain 0.00044
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) gi|224926826|ref|NP_001139267.1|
Sequence length 756
Comment SH2B adapter protein 1 isoform 1 [Homo sapiens]
Sequence
MNGAPSPEDGASPSSPPLPPPPPPSWREFCESHARAAALDFARRFRLYLASHPQYAGPGA
EAAFSRRFAELFLQHFEAEVARASGSLSPPILAPLSPGAEISPHDLSLESCRVGGPLAVL
GPSRSSEDLAGPLPSSVSSSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGTVDPPS
SAGPLETSSGPPVLGGNSNSNSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGAL
KDGAGMVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQKCRLLLRSEGEG
GGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVKVEGPSEYIMETVD
AQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTDSLELSCLNHSESLPS
QDLLLGPSESNDRLSQGAYGGLSDRPSASISPSSASIAASHFDSMELLPPELPPRIPIEE
GPPTGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQPLSGYPWFHGMLSRLKAAQL
VLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDM
LEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQEPTTSHDPPQPPEPPSWTDPPQPGAEEA
SRAPEVAAAAAAAAKERQEKEKAGGGGVPEELVPVVELVPVVELEEAIAPGSEAQGAGSG
GDAGVPPMVQLQQSPLGGDGEEGGHPRAINNQYSFV
Download sequence
Identical sequences A0A024QZD2 Q9NRF2
ENSP00000321221 gi|224926826|ref|NP_001139267.1| ENSP00000321221 ENSP00000481709 ENSP00000321221 NP_001139267.1.87134 NP_001139267.1.92137 NP_001295222.1.87134 NP_001295222.1.92137 XP_016878603.1.92137 XP_016878604.1.92137 XP_016878605.1.92137

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