SUPERFAMILY 1.75 HMM library and genome assignments server

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Domain assignment for gi|226246577|ref|NP_001139675.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|226246577|ref|NP_001139675.1|
Domain Number 1 Region: 57-367
Classification Level Classification E-value
Superfamily Ras GEF 2.35e-62
Family Ras GEF 0.0026
Further Details:      
 
Domain Number 2 Region: 435-499
Classification Level Classification E-value
Superfamily Cysteine-rich domain 2.09e-17
Family Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) 0.002
Further Details:      
 
Weak hits

Sequence:  gi|226246577|ref|NP_001139675.1|
Domain Number - Region: 374-406
Classification Level Classification E-value
Superfamily EF-hand 0.00165
Family Calmodulin-like 0.049
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) gi|226246577|ref|NP_001139675.1|
Sequence length 581
Comment RAS guanyl-releasing protein 4 isoform c [Homo sapiens]
Sequence
MNRKDSKRKSHQECTGKIGGRGRPRQVRRHKTCPSPREISKVMASMNLGLLSEGGCSEDE
LLEKCIQSFDSAGSLCHEDHMLNMVLAMHSWVLPSADLAARLLTSYQKATGDTQELRRLQ
ICHLVRYWLMRHPEVMHQDPQLEEVIGRFWATVAREGNSAQRRLGDSSDLLSPGGPGPPL
PMSSPGLGKKRKVSLLFDHLETGELAQHLTYLEFRSFQAITPQDLRSYVLQGSVRGCPAL
EGSVGLSNSVSRWVQVMVLSRPGPLQRAQVLDKFIHVAQRLHQLQNFNTLMAVTGGLCHS
AISRLKDSHAHLSPDSTKLSLDLFYTEDEIYELSYAREPRCPKSLPPSPFNAPLVVEWAP
GVTPKPDRVTLGRHVEQLVESVFKNYDPEGRGTISQEDFERLSGNFPFACHGLHPPPRQG
RGSFSREELTGYLLRASAICSKLGLAFLHTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCR
ECGLCCHKHCRDQVKVECKKRPGAKGDAGPPGAPVPSTPAPHASCGSEENHSYTLSLEPE
TGCQLRHAWTQTESPHPSWETDTVPCPVMDPPSTASSKLDS
Download sequence
Identical sequences ENSP00000411878 ENSP00000411878 ENSP00000479078 gi|226246577|ref|NP_001139675.1| NP_001139675.1.87134 NP_001139675.1.92137

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