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Domain assignment for gi|226246581|ref|NP_001139677.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|226246581|ref|NP_001139677.1|
Domain Number 1 Region: 57-425
Classification Level Classification E-value
Superfamily Ras GEF 5.36e-78
Family Ras GEF 0.0029
Further Details:      
 
Domain Number 2 Region: 493-557
Classification Level Classification E-value
Superfamily Cysteine-rich domain 2.39e-17
Family Protein kinase cysteine-rich domain (cys2, phorbol-binding domain) 0.002
Further Details:      
 
Weak hits

Sequence:  gi|226246581|ref|NP_001139677.1|
Domain Number - Region: 432-464
Classification Level Classification E-value
Superfamily EF-hand 0.00178
Family Calmodulin-like 0.049
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) gi|226246581|ref|NP_001139677.1|
Sequence length 639
Comment RAS guanyl-releasing protein 4 isoform e [Homo sapiens]
Sequence
MNRKDSKRKSHQECTGKIGGRGRPRQVRRHKTCPSPREISKVMASMNLGLLSEGGCSEDE
LLEKCIQSFDSAGSLCHEDHMLNMVLAMHSWVLPSADLAARLLTSYQKATGDTQELRRLQ
ICHLVRYWLMRHPEVMHQDPQLEEVIGRFWATVAREGNSAQRRLGDSSDLLSPGGPGPPL
PMSSPGLGKKRKVSLLFDHLETGELAQHLTYLEFRSFQAITVMVLSRPGPLQRAQVLDKF
IHVAQRLHQLQNFNTLMAVTGGLCHSAISRLKDSHAHLSPDSTKALLELTELLASHNNYA
RYRRTWAGCAGFRLPVLGVHLKDLVSLHEAQPDRLPDGRLHLPKLNNLYLRLQELVALQG
QHPPCSANEDLLHLLTLSLDLFYTEDEIYELSYAREPRCPKSLPPSPFNAPLVVEWAPGV
TPKPDRVTLGRHVEQLVESVFKNYDPEGRGTISQEDFERLSGNFPFACHGLHPPPRQGRG
SFSREELTGYLLRASAICSKLGLAFLHTFHEVTFRKPTFCDSCSGFLWGVTKQGYRCREC
GLCCHKHCRDQVKVECKKRPGAKGDAGPPGAPVPSTPAPHASCGSEENHSYTLSLEPETG
CQLRHAWTQTESPHPSWETDTVPCPVMDPPSTASSKLDS
Download sequence
Identical sequences ENSP00000416463 gi|226246581|ref|NP_001139677.1| ENSP00000416463 NP_001139677.1.87134 NP_001139677.1.92137

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