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Domain assignment for gi|29725609|ref|NP_005219.2| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|29725609|ref|NP_005219.2|
Domain Number 1 Region: 708-1003
Classification Level Classification E-value
Superfamily Protein kinase-like (PK-like) 8.23e-78
Family Protein kinases, catalytic subunit 0.0000000000302
Further Details:      
 
Domain Number 2 Region: 328-520
Classification Level Classification E-value
Superfamily L domain-like 1.64e-46
Family L domain 0.000000145
Further Details:      
 
Domain Number 3 Region: 31-209
Classification Level Classification E-value
Superfamily L domain-like 3.97e-43
Family L domain 0.00000018
Further Details:      
 
Domain Number 4 Region: 505-636
Classification Level Classification E-value
Superfamily Growth factor receptor domain 1.71e-24
Family Growth factor receptor domain 0.0000000482
Further Details:      
 
Domain Number 5 Region: 186-339
Classification Level Classification E-value
Superfamily Growth factor receptor domain 1.81e-19
Family Growth factor receptor domain 0.0000000179
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) gi|29725609|ref|NP_005219.2|
Sequence length 1210
Comment epidermal growth factor receptor isoform a precursor [Homo sapiens]
Sequence
MRPSGTAGAALLALLAALCPASRALEEKKVCQGTSNKLTQLGTFEDHFLSLQRMFNNCEV
VLGNLEITYVQRNYDLSFLKTIQEVAGYVLIALNTVERIPLENLQIIRGNMYYENSYALA
VLSNYDANKTGLKELPMRNLQEILHGAVRFSNNPALCNVESIQWRDIVSSDFLSNMSMDF
QNHLGSCQKCDPSCPNGSCWGAGEENCQKLTKIICAQQCSGRCRGKSPSDCCHNQCAAGC
TGPRESDCLVCRKFRDEATCKDTCPPLMLYNPTTYQMDVNPEGKYSFGATCVKKCPRNYV
VTDHGSCVRACGADSYEMEEDGVRKCKKCEGPCRKVCNGIGIGEFKDSLSINATNIKHFK
NCTSISGDLHILPVAFRGDSFTHTPPLDPQELDILKTVKEITGFLLIQAWPENRTDLHAF
ENLEIIRGRTKQHGQFSLAVVSLNITSLGLRSLKEISDGDVIISGNKNLCYANTINWKKL
FGTSGQKTKIISNRGENSCKATGQVCHALCSPEGCWGPEPRDCVSCRNVSRGRECVDKCN
LLEGEPREFVENSECIQCHPECLPQAMNITCTGRGPDNCIQCAHYIDGPHCVKTCPAGVM
GENNTLVWKYADAGHVCHLCHPNCTYGCTGPGLEGCPTNGPKIPSIATGMVGALLLLLVV
ALGIGLFMRRRHIVRKRTLRRLLQERELVEPLTPSGEAPNQALLRILKETEFKKIKVLGS
GAFGTVYKGLWIPEGEKVKIPVAIKELREATSPKANKEILDEAYVMASVDNPHVCRLLGI
CLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAA
RNVLVKTPQHVKITDFGLAKLLGAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSY
GVTVWELMTFGSKPYDGIPASEISSILEKGERLPQPPICTIDVYMIMVKCWMIDADSRPK
FRELIIEFSKMARDPQRYLVIQGDERMHLPSPTDSNFYRALMDEEDMDDVVDADEYLIPQ
QGFFSSPSTSRTPLLSSLSATSNNSTVACIDRNGLQSCPIKEDSFLQRYSSDPTGALTED
SIDDTFLPVPEYINQSVPKRPAGSVQNPVYHNQPLNPAPSRDPHYQDPHSTAVGNPEYLN
TVQPTCVNSTFDSPAHWAQKGSHQISLDNPDYQQDFFPKEAKPNGIFKGSTAENAEYLRV
APQSSEFIGA
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Identical sequences P00533
gi|29725609|ref|NP_005219.2| 9606.ENSP00000275493 ENSP00000275493 NP_005219.2.87134 NP_005219.2.92137 ENSP00000410031 ar_001000562.3 ar_001000562.4 ENSP00000275493

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