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Domain assignment for gi|31317292|ref|NP_065162.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|31317292|ref|NP_065162.1|
Domain Number 1 Region: 386-750
Classification Level Classification E-value
Superfamily Hect, E3 ligase catalytic domain 2.09e-126
Family Hect, E3 ligase catalytic domain 0.00000000515
Further Details:      
 
Domain Number 2 Region: 13-138
Classification Level Classification E-value
Superfamily C2 domain (Calcium/lipid-binding domain, CaLB) 1.18e-22
Family PLC-like (P variant) 0.034
Further Details:      
 
Domain Number 3 Region: 301-341
Classification Level Classification E-value
Superfamily WW domain 0.000000000000362
Family WW domain 0.00079
Further Details:      
 
Domain Number 4 Region: 231-268
Classification Level Classification E-value
Superfamily WW domain 0.00000000209
Family WW domain 0.003
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) gi|31317292|ref|NP_065162.1|
Sequence length 757
Comment E3 ubiquitin-protein ligase SMURF1 isoform 1 [Homo sapiens]
Sequence
MSNPGTRRNGSSIKIRLTVLCAKNLAKKDFFRLPDPFAKIVVDGSGQCHSTDTVKNTLDP
KWNQHYDLYVGKTDSITISVWNHKKIHKKQGAGFLGCVRLLSNAISRLKDTGYQRLDLCK
LNPSDTDAVRGQIVVSLQTRDRIGTGGSVVDCRGLLENEGTVYEDSGPGRPLSCFMEEPA
PYTDSTGAAAGGGNCRFVESPSQDQRLQAQRLRNPDVRGSLQTPQNRPHGHQSPELPEGY
EQRTTVQGQVYFLHTQTGVSTWHDPRIPSPSGTIPGGDAAFLYEFLLQGHTSEPRDLNSV
NCDELGPLPPGWEVRSTVSGRIYFVDHNNRTTQFTDPRLHHIMNHQCQLKEPSQPLPLPS
EGSLEDEELPAQRYERDLVQKLKVLRHELSLQQPQAGHCRIEVSREEIFEESYRQIMKMR
PKDLKKRLMVKFRGEEGLDYGGVAREWLYLLCHEMLNPYYGLFQYSTDNIYMLQINPDSS
INPDHLSYFHFVGRIMGLAVFHGHYINGGFTVPFYKQLLGKPIQLSDLESVDPELHKSLV
WILENDITPVLDHTFCVEHNAFGRILQHELKPNGRNVPVTEENKKEYVRLYVNWRFMRGI
EAQFLALQKGFNELIPQHLLKPFDQKELELIIGGLDKIDLNDWKSNTRLKHCVADSNIVR
WFWQAVETFDEERRARLLQFVTGSTRVPLQGFKALQGSTGAAGPRLFTIHLIDANTDNLP
KAHTCFNRIDIPPYESYEKLYEKLLTAVEETCGFAVE
Download sequence
Identical sequences H2R545 Q9HCE7
NP_065162.1.87134 NP_065162.1.92137 XP_528043.3.37143 ENSPTRP00000047812 ENSP00000354621 ENSP00000355326 HR4392 ENSPTRP00000047812 ENSP00000354621 9606.ENSP00000354621 gi|31317292|ref|NP_065162.1|

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