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Domain assignment for gi|54792096|ref|NP_004439.2| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|54792096|ref|NP_004439.2|
Domain Number 1 Region: 716-992
Classification Level Classification E-value
Superfamily Protein kinase-like (PK-like) 7.55e-78
Family Protein kinases, catalytic subunit 0.000000000763
Further Details:      
 
Domain Number 2 Region: 47-214
Classification Level Classification E-value
Superfamily L domain-like 2.84e-42
Family L domain 0.000000415
Further Details:      
 
Domain Number 3 Region: 337-525
Classification Level Classification E-value
Superfamily L domain-like 3.69e-42
Family L domain 0.000000245
Further Details:      
 
Domain Number 4 Region: 511-642
Classification Level Classification E-value
Superfamily Growth factor receptor domain 7e-22
Family Growth factor receptor domain 0.000000107
Further Details:      
 
Domain Number 5 Region: 189-343
Classification Level Classification E-value
Superfamily Growth factor receptor domain 1.81e-16
Family Growth factor receptor domain 0.0000000127
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) gi|54792096|ref|NP_004439.2|
Sequence length 1255
Comment receptor tyrosine-protein kinase erbB-2 isoform a [Homo sapiens]
Sequence
MELAALCRWGLLLALLPPGAASTQVCTGTDMKLRLPASPETHLDMLRHLYQGCQVVQGNL
ELTYLPTNASLSFLQDIQEVQGYVLIAHNQVRQVPLQRLRIVRGTQLFEDNYALAVLDNG
DPLNNTTPVTGASPGGLRELQLRSLTEILKGGVLIQRNPQLCYQDTILWKDIFHKNNQLA
LTLIDTNRSRACHPCSPMCKGSRCWGESSEDCQSLTRTVCAGGCARCKGPLPTDCCHEQC
AAGCTGPKHSDCLACLHFNHSGICELHCPALVTYNTDTFESMPNPEGRYTFGASCVTACP
YNYLSTDVGSCTLVCPLHNQEVTAEDGTQRCEKCSKPCARVCYGLGMEHLREVRAVTSAN
IQEFAGCKKIFGSLAFLPESFDGDPASNTAPLQPEQLQVFETLEEITGYLYISAWPDSLP
DLSVFQNLQVIRGRILHNGAYSLTLQGLGISWLGLRSLRELGSGLALIHHNTHLCFVHTV
PWDQLFRNPHQALLHTANRPEDECVGEGLACHQLCARGHCWGPGPTQCVNCSQFLRGQEC
VEECRVLQGLPREYVNARHCLPCHPECQPQNGSVTCFGPEADQCVACAHYKDPPFCVARC
PSGVKPDLSYMPIWKFPDEEGACQPCPINCTHSCVDLDDKGCPAEQRASPLTSIISAVVG
ILLVVVLGVVFGILIKRRQQKIRKYTMRRLLQETELVEPLTPSGAMPNQAQMRILKETEL
RKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSP
YVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVR
LVHRDLAARNVLVKSPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFT
HQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWM
IDSECRPRFRELVSEFSRMARDPQRFVVIQNEDLGPASPLDSTFYRSLLEDDDMGDLVDA
EEYLVPQQGFFCPDPAPGAGGMVHHRHRSSSTRSGGGDLTLGLEPSEEEAPRSPLAPSEG
AGSDVFDGDLGMGAAKGLQSLPTHDPSPLQRYSEDPTVPLPSETDGYVAPLTCSPQPEYV
NQPDVRPQPPSPREGPLPAARPAGATLERPKTLSPGKNGVVKDVFAFGGAVENPEYLTPQ
GGAAPQPHPPPAFSPAFDNLYYWDQDPPERGAPPSTFKGTPTAENPEYLGLDVPV
Download sequence
Identical sequences P04626 X5DNK3
NP_004439.2.87134 NP_004439.2.92137 ENSP00000269571 9606.ENSP00000269571 ENSP00000269571 ENSP00000269571 gi|54792096|ref|NP_004439.2|

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