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Domain assignment for gi|224926828|ref|NP_001139268.1| from Homo sapiens

Domain architecture


Domain assignment details

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Strong hits

Sequence:  gi|224926828|ref|NP_001139268.1|
Domain Number 1 Region: 267-381
Classification Level Classification E-value
Superfamily PH domain-like 2.18e-32
Family Pleckstrin-homology domain (PH domain) 0.00008
Further Details:      
 
Domain Number 2 Region: 524-627
Classification Level Classification E-value
Superfamily SH2 domain 4.58e-25
Family SH2 domain 0.0000127
Further Details:      
 
Domain Number 3 Region: 24-83
Classification Level Classification E-value
Superfamily Phenylalanine zipper 5.36e-22
Family Adapter protein APS, dimerisation domain 0.00044
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) gi|224926828|ref|NP_001139268.1|
Sequence length 671
Comment SH2B adapter protein 1 isoform 2 [Homo sapiens]
Sequence
MNGAPSPEDGASPSSPPLPPPPPPSWREFCESHARAAALDFARRFRLYLASHPQYAGPGA
EAAFSRRFAELFLQHFEAEVARASGSLSPPILAPLSPGAEISPHDLSLESCRVGGPLAVL
GPSRSSEDLAGPLPSSVSSSSTTSSKPKLKKRFSLRSVGRSVRGSVRGILQWRGTVDPPS
SAGPLETSSGPPVLGGNSNSNSSGGAGTVGRGLVSDGTSPGERWTHRFERLRLSRGGGAL
KDGAGMVQREELLSFMGAEEAAPDPAGVGRGGGVAGPPSGGGGQPQWQKCRLLLRSEGEG
GGGSRLEFFVPPKASRPRLSIPCSSITDVRTTTALEMPDRENTFVVKVEGPSEYIMETVD
AQHVKAWVSDIQECLSPGPCPATSPRPMTLPLAPGTSFLTRENTDSLELSCLNHSESLPS
QDLLLGPSESNDRLSQGAYGGLSDRPSASISPSSASIAASHFDSMELLPPELPPRIPIEE
GPPTGTVHPLSAPYPPLDTPETATGSFLFQGEPEGGEGDQPLSGYPWFHGMLSRLKAAQL
VLTGGTGSHGVFLVRQSETRRGEYVLTFNFQGKAKHLRLSLNEEGQCRVQHLWFQSIFDM
LEHFRVHPIPLESGGSSDVVLVSYVPSSQRQQGREQAGSHAGVCEGDGCHPDASCTLMPF
GASDCVTDHLP
Download sequence
Identical sequences A0A024QZC2
9606.ENSP00000337163 ENSP00000337163 ENSP00000378903 NP_001139268.1.87134 NP_001139268.1.92137 NP_001139284.1.87134 NP_001139284.1.92137 NP_056318.2.87134 NP_056318.2.92137 gi|224926822|ref|NP_001139284.1| gi|224926824|ref|NP_056318.2| gi|224926828|ref|NP_001139268.1| ENSP00000337163 ENSP00000378903

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