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Domain assignment for ENSP00000349393 from Homo sapiens 76_38

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000349393
Domain Number 1 Region: 204-452
Classification Level Classification E-value
Superfamily DNA ligase/mRNA capping enzyme, catalytic domain 1.46e-47
Family ATP-dependent DNA ligase catalytic domain 0.00096
Further Details:      
 
Domain Number 2 Region: 459-604
Classification Level Classification E-value
Superfamily Nucleic acid-binding proteins 3.94e-32
Family DNA ligase/mRNA capping enzyme postcatalytic domain 0.00066
Further Details:      
 
Domain Number 3 Region: 620-748
Classification Level Classification E-value
Superfamily BRCT domain 5.63e-21
Family DNA topoisomerase II binding protein 1, TopBP1 0.045
Further Details:      
 
Domain Number 4 Region: 9-253
Classification Level Classification E-value
Superfamily ATP-dependent DNA ligase DNA-binding domain 2.22e-16
Family ATP-dependent DNA ligase DNA-binding domain 0.01
Further Details:      
 
Domain Number 5 Region: 844-911
Classification Level Classification E-value
Superfamily BRCT domain 0.00000000000436
Family BRCT domain 0.064
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000349393   Gene: ENSG00000174405   Transcript: ENST00000356922
Sequence length 911
Comment pep:known chromosome:GRCh38:13:108207446:108214782:-1 gene:ENSG00000174405 transcript:ENST00000356922 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MAASQTSQTVASHVPFADLCSTLERIQKSKGRAEKIRHFREFLDSWRKFHDALHKNHKDV
TDSFYPAMRLILPQLERERMAYGIKETMLAKLYIELLNLPRDGKDALKLLNYRTPTGTHG
DAGDFAMIAYFVLKPRCLQKGSLTIQQVNDLLDSIASNNSAKRKDLIKKSLLQLITQSSA
LEQKWLIRMIIKDLKLGVSQQTIFSVFHNDAAELHNVTTDLEKVCRQLHDPSVGLSDISI
TLFSAFKPMLAAIADIEHIEKDMKHQSFYIETKLDGERMQMHKDGDVYKYFSRNGYNYTD
QFGASPTEGSLTPFIHNAFKADIQICILDGEMMAYNPNTQTFMQKGTKFDIKRMVEDSDL
QTCYCVFDVLMVNNKKLGHETLRKRYEILSSIFTPIPGRIEIVQKTQAHTKNEVIDALNE
AIDKREEGIMVKQPLSIYKPDKRGEGWLKIKPEYVSGLMDELDILIVGGYWGKGSRGGMM
SHFLCAVAEKPPPGEKPSVFHTLSRVGSGCTMKELYDLGLKLAKYWKPFHRKAPPSSILC
GTEKPEVYIEPCNSVIVQIKAAEIVPSDMYKTGCTLRFPRIEKIRDDKEWHECMTLDDLE
QLRGKASGKLASKHLYIGGDDEPQEKKRKAAPKMKKVIGIIEHLKAPNLTNVNKISNIFE
DVEFCVMSGTDSQPKPDLENRIAEFGGYIVQNPGPDTYCVIAGSENIRVKNIILSNKHDV
VKPAWLLECFKTKSFVPWQPRFMIHMCPSTKEHFAREYDCYGDSYFIDTDLNQLKEVFSG
IKNSNEQTPEEMASLIADLEYRYSWDCSPLSMFRRHTVYLDSYAVINDLSTKNEGTRLAI
KALELRFHGAKVVSCLAEGVSHVIIGEDHSRVADFKAFRRTFKRKFKILKESWVTDSIDK
CELQEENQYLI
Download sequence
Identical sequences A0A024RE06 P49917
NP_001091738.1.87134 NP_001091738.1.92137 NP_002303.2.87134 NP_002303.2.92137 NP_996820.1.87134 NP_996820.1.92137 XP_005254113.1.92137 XP_005254114.1.92137 XP_005254115.1.92137 XP_006720014.1.92137 XP_006720015.1.92137 XP_011519393.1.92137 XP_011519394.1.92137 XP_016876058.1.92137 XP_016876059.1.92137 XP_016876060.1.92137 9606.ENSP00000349393 ENSP00000349393 ENSP00000385955 ENSP00000402030 ENSP00000484288 NYSGRC-23199993 gi|148539894|ref|NP_001091738.1| gi|23199993|ref|NP_002303.2| gi|46255052|ref|NP_996820.1| ENSP00000349393 ENSP00000349393 ENSP00000385955 ENSP00000402030

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