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Domain assignment for ENSP00000295956 from Homo sapiens 75_37

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000295956
Domain Number 1 Region: 7-237
Classification Level Classification E-value
Superfamily Calponin-homology domain, CH-domain 4.73e-78
Family Calponin-homology domain, CH-domain 0.0000937
Further Details:      
 
Domain Number 2 Region: 1305-1417
Classification Level Classification E-value
Superfamily E set domains 2.27e-35
Family Filamin repeat (rod domain) 0.00000262
Further Details:      
 
Domain Number 3 Region: 1419-1527
Classification Level Classification E-value
Superfamily E set domains 2.94e-33
Family Filamin repeat (rod domain) 0.00000307
Further Details:      
 
Domain Number 4 Region: 1216-1327
Classification Level Classification E-value
Superfamily E set domains 1.4e-31
Family Filamin repeat (rod domain) 0.000000834
Further Details:      
 
Domain Number 5 Region: 1494-1611
Classification Level Classification E-value
Superfamily E set domains 6.27e-31
Family Filamin repeat (rod domain) 0.0000281
Further Details:      
 
Domain Number 6 Region: 1592-1707
Classification Level Classification E-value
Superfamily E set domains 6.47e-31
Family Filamin repeat (rod domain) 0.0000039
Further Details:      
 
Domain Number 7 Region: 1037-1127
Classification Level Classification E-value
Superfamily E set domains 1.2e-30
Family Filamin repeat (rod domain) 0.00000301
Further Details:      
 
Domain Number 8 Region: 430-547
Classification Level Classification E-value
Superfamily E set domains 1.07e-29
Family Filamin repeat (rod domain) 0.00065
Further Details:      
 
Domain Number 9 Region: 720-843
Classification Level Classification E-value
Superfamily E set domains 7.34e-29
Family Filamin repeat (rod domain) 0.00087
Further Details:      
 
Domain Number 10 Region: 1817-1912
Classification Level Classification E-value
Superfamily E set domains 2e-28
Family Filamin repeat (rod domain) 0.0000128
Further Details:      
 
Domain Number 11 Region: 823-943
Classification Level Classification E-value
Superfamily E set domains 2.6e-28
Family Filamin repeat (rod domain) 0.00044
Further Details:      
 
Domain Number 12 Region: 643-752
Classification Level Classification E-value
Superfamily E set domains 3e-27
Family Filamin repeat (rod domain) 0.00075
Further Details:      
 
Domain Number 13 Region: 2188-2284
Classification Level Classification E-value
Superfamily E set domains 5.34e-27
Family Filamin repeat (rod domain) 0.00000992
Further Details:      
 
Domain Number 14 Region: 1998-2093
Classification Level Classification E-value
Superfamily E set domains 1.67e-26
Family Filamin repeat (rod domain) 0.00000323
Further Details:      
 
Domain Number 15 Region: 1130-1239
Classification Level Classification E-value
Superfamily E set domains 1.67e-26
Family Filamin repeat (rod domain) 0.00000305
Further Details:      
 
Domain Number 16 Region: 352-451
Classification Level Classification E-value
Superfamily E set domains 3.54e-25
Family Filamin repeat (rod domain) 0.00084
Further Details:      
 
Domain Number 17 Region: 252-349
Classification Level Classification E-value
Superfamily E set domains 3.67e-25
Family Filamin repeat (rod domain) 0.00086
Further Details:      
 
Domain Number 18 Region: 2511-2601
Classification Level Classification E-value
Superfamily E set domains 6.67e-25
Family Filamin repeat (rod domain) 0.0000165
Further Details:      
 
Domain Number 19 Region: 2382-2473
Classification Level Classification E-value
Superfamily E set domains 1.93e-24
Family Filamin repeat (rod domain) 0.0000148
Further Details:      
 
Domain Number 20 Region: 2289-2380
Classification Level Classification E-value
Superfamily E set domains 5.6e-24
Family Filamin repeat (rod domain) 0.0000166
Further Details:      
 
Domain Number 21 Region: 537-639
Classification Level Classification E-value
Superfamily E set domains 6.47e-24
Family Filamin repeat (rod domain) 0.0002
Further Details:      
 
Domain Number 22 Region: 951-1051
Classification Level Classification E-value
Superfamily E set domains 1.34e-21
Family Filamin repeat (rod domain) 0.00099
Further Details:      
 
Domain Number 23 Region: 2110-2205
Classification Level Classification E-value
Superfamily E set domains 6.67e-21
Family Filamin repeat (rod domain) 0.00001
Further Details:      
 
Domain Number 24 Region: 1908-1996
Classification Level Classification E-value
Superfamily E set domains 5.87e-18
Family Filamin repeat (rod domain) 0.00000529
Further Details:      
 
Domain Number 25 Region: 1755-1831
Classification Level Classification E-value
Superfamily E set domains 3e-16
Family Filamin repeat (rod domain) 0.00012
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000295956   Gene: ENSG00000136068   Transcript: ENST00000295956
Sequence length 2602
Comment pep:known chromosome:GRCh37:3:57994127:58157978:1 gene:ENSG00000136068 transcript:ENST00000295956 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MPVTEKDLAEDAPWKKIQQNTFTRWCNEHLKCVNKRIGNLQTDLSDGLRLIALLEVLSQK
RMYRKYHQRPTFRQMQLENVSVALEFLDRESIKLVSIDSKAIVDGNLKLILGLVWTLILH
YSISMPVWEDEGDDDAKKQTPKQRLLGWIQNKIPYLPITNFNQNWQDGKALGALVDSCAP
GLCPDWESWDPQKPVDNAREAMQQADDWLGVPQVITPEEIIHPDVDEHSVMTYLSQFPKA
KLKPGAPLKPKLNPKKARAYGRGIEPTGNMVKQPAKFTVDTISAGQGDVMVFVEDPEGNK
EEAQVTPDSDKNKTYSVEYLPKVTGLHKVTVLFAGQHISKSPFEVSVDKAQGDASKVTAK
GPGLEAVGNIANKPTYFDIYTAGAGVGDIGVEVEDPQGKNTVELLVEDKGNQVYRCVYKP
MQPGPHVVKIFFAGDTIPKSPFVVQVGEACNPNACRASGRGLQPKGVRIRETTDFKVDTK
AAGSGELGVTMKGPKGLEELVKQKDFLDGVYAFEYYPSTPGRYSIAITWGGHHIPKSPFE
VQVGPEAGMQKVRAWGPGLHGGIVGRSADFVVESIGSEVGSLGFAIEGPSQAKIEYNDQN
DGSCDVKYWPKEPGEYAVHIMCDDEDIKDSPYMAFIHPATGGYNPDLVRAYGPGLEKSGC
IVNNLAEFTVDPKDAGKAPLKIFAQDGEGQRIDIQMKNRMDGTYACSYTPVKAIKHTIAV
VWGGVNIPHSPYRVNIGQGSHPQKVKVFGPGVERSGLKANEPTHFTVDCTEAGEGDVSVG
IKCDARVLSEDEEDVDFDIIHNANDTFTVKYVPPAAGRYTIKVLFASQEIPASPFRVKVD
PSHDASKVKAEGPGLSKAGVENGKPTHFTVYTKGAGKAPLNVQFNSPLPGDAVKDLDIID
NYDYSHTVKYTPTQQGNMQVLVTYGGDPIPKSPFTVGVAAPLDLSKIKLNGLENRVEVGK
DQEFTVDTRGAGGQGKLDVTILSPSRKVVPCLVTPVTGRENSTAKFIPREEGLYAVDVTY
DGHPVPGSPYTVEASLPPDPSKVKAHGPGLEGGLVGKPAEFTIDTKGAGTGGLGLTVEGP
CEAKIECSDNGDGTCSVSYLPTKPGEYFVNILFEEVHIPGSPFKADIEMPFDPSKVVASG
PGLEHGKVGEAGLLSVDCSEAGPGALGLEAVSDSGTKAEVSIQNNKDGTYAVTYVPLTAG
MYTLTMKYGGELVPHFPARVKVEPAVDTSRIKVFGPGIEGKDVFREATTDFTVDSRPLTQ
VGGDHIKAHIANPSGASTECFVTDNADGTYQVEYTPFEKGLHVVEVTYDDVPIPNSPFKV
AVTEGCQPSRVQAQGPGLKEAFTNKPNVFTVVTRGAGIGGLGITVEGPSESKINCRDNKD
GSCSAEYIPFAPGDYDVNITYGGAHIPGSPFRVPVKDVVDPSKVKIAGPGLGSGVRARVL
QSFTVDSSKAGLAPLEVRVLGPRGLVEPVNVVDNGDGTHTVTYTPSQEGPYMVSVKYADE
EIPRSPFKVKVLPTYDASKVTASGPGLSSYGVPASLPVDFAIDARDAGEGLLAVQITDQE
GKPKRAIVHDNKDGTYAVTYIPDKTGRYMIGVTYGGDDIPLSPYRIRATQTGDASKCLAT
GPGIASTVKTGEEVGFVVDAKTAGKGKVTCTVLTPDGTEAEADVIENEDGTYDIFYTAAK
PGTYVIYVRFGGVDIPNSPFTVMATDGEVTAVEEAPVNACPPGFRPWVTEEAYVPVSDMN
GLGFKPFDLVIPFAVRKGEITGEVHMPSGKTATPEIVDNKDGTVTVRYAPTEVGLHEMHI
KYMGSHIPESPLQFYVNYPNSGSVSAYGPGLVYGVANKTATFTIVTEDAGEGGLDLAIEG
PSKAEISCIDNKDGTCTVTYLPTLPGDYSILVKYNDKHIPGSPFTAKITDDSRRCSQVKL
GSAADFLLDISETDLSSLTASIKAPSGRDEPCLLKRLPNNHIGISFIPREVGEHLVSIKK
NGNHVANSPVSIMVVQSEIGDARRAKVYGRGLSEGRTFEMSDFIVDTRDAGYGGISLAVE
GPSKVDIQTEDLEDGTCKVSYFPTVPGVYIVSTKFADEHVPGSPFTVKISGEGRVKESIT
RTSRAPSVATVGSICDLNLKIPEINSSDMSAHVTSPSGRVTEAEIVPMGKNSHCVRFVPQ
EMGVHTVSVKYRGQHVTGSPFQFTVGPLGEGGAHKVRAGGPGLERGEAGVPAEFSIWTRE
AGAGGLSIAVEGPSKAEITFDDHKNGSCGVSYIAQEPGNYEVSIKFNDEHIPESPYLVPV
IAPSDDARRLTVMSLQESGLKVNQPASFAIRLNGAKGKIDAKVHSPSGAVEECHVSELEP
DKYAVRFIPHENGVHTIDVKFNGSHVVGSPFKVRVGEPGQAGNPALVSAYGTGLEGGTTG
IQSEFFINTTRAGPGTLSVTIEGPSKVKMDCQETPEGYKVMYTPMAPGNYLISVKYGGPN
HIVGSPFKAKVTGQRLVSPGSANETSSILVESVTRSSTETCYSAIPKASSDASKVTSKGA
GLSKAFVGQKSSFLVDCSKAGSNMLLIGVHGPTTPCEEVSMKHVGNQQYNVTYVVKERGD
YVLAVKWGEEHIPGSPFHVTVP
Download sequence
Identical sequences O75369
NP_001448.2.87134 NP_001448.2.92137 9606.ENSP00000295956 ENSP00000295956 gi|105990514|ref|NP_001448.2| ENSP00000295956

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