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Domain assignment for ENSP00000394307 from Homo sapiens 75_37

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000394307
Domain Number 1 Region: 519-638
Classification Level Classification E-value
Superfamily GTPase activation domain, GAP 3.73e-25
Family BCR-homology GTPase activation domain (BH-domain) 0.001
Further Details:      
 
Domain Number 2 Region: 323-445
Classification Level Classification E-value
Superfamily PH domain-like 1.75e-19
Family Pleckstrin-homology domain (PH domain) 0.021
Further Details:      
 
Domain Number 3 Region: 19-98
Classification Level Classification E-value
Superfamily SH3-domain 0.0000000000866
Family SH3-domain 0.0025
Further Details:      
 
Domain Number 4 Region: 218-247
Classification Level Classification E-value
Superfamily WW domain 0.00000993
Family WW domain 0.0036
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000394307   Gene: ENSG00000123329   Transcript: ENST00000424809
Sequence length 640
Comment pep:known chromosome:GRCh37:12:57866047:57873415:-1 gene:ENSG00000123329 transcript:ENST00000424809 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MLSSRWWPSSWGILGLGPRSPPRGSQLCALYAFTYTGADGQQVSLAEGDRFLLLRKTNSD
WWLARRLEAPSTSRPIFVPAAYMIEESIPSQSPTTVIPGQLLWTPGPKLFHGSLEELSQA
LPSRAQASSEQPPPLPRKMCRSVSTDNLSPSLLKPFQEGPSGRSLSQEDLPSEASASTAG
PQPLMSEPPVYCNLVDLRRCPRSPPPGPACPLLQRLDAWEQHLDPNSGRCFYINSLTGCK
SWKPPRRSRSETNPGSMEGTQTLKRNNDVLQPQAKGFRSDTGTPEPLDPQGSLSLSQRTS
QLDPPALQAPRPLPQLLDDPHEVEKSGLLNMTKIAQGGRKLRKNWGPSWVVLTGNSLVFY
REPPPTAPSSGWGPAGSRPESSVDLRGAALAHGRHLSSRRNVLHIRTIPGHEFLLQSDHE
TELRAWHRALRTVIERLDRENPLELRLSGSGPAELSAGEDEEEESELVSKPLLRLSSRRS
SIRGPEGTEQNRVRNKLKRLIAKRPPLQSLQERGLLRDQVFGCQLESLCQREGDTVPSFL
RLCIAAVDKRGLDVDGIYRVSGNLAVVQKLRFLVDRERAVTSDGRYVFPEQPGQEGRLDL
DSTEWDDIHVVTGALKLFLRELPQPLVPPLLLPHFRAALG
Download sequence
Identical sequences gi|122939151|ref|NP_001073626.1| ENSP00000394307 NP_001073626.1.87134 NP_001073626.1.92137 XP_011536961.1.92137 ENSP00000394307

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