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Domain assignment for ENSP00000438011 from Homo sapiens 75_37

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000438011
Domain Number 1 Region: 237-433,534-790
Classification Level Classification E-value
Superfamily Ras GEF 2.75e-116
Family Ras GEF 0.00015
Further Details:      
 
Domain Number 2 Region: 1-118
Classification Level Classification E-value
Superfamily "Winged helix" DNA-binding domain 8.71e-40
Family DEP domain 0.000000548
Further Details:      
 
Domain Number 3 Region: 441-543
Classification Level Classification E-value
Superfamily Ubiquitin-like 1.27e-36
Family Ras-binding domain, RBD 0.0012
Further Details:      
 
Domain Number 4 Region: 111-240
Classification Level Classification E-value
Superfamily cAMP-binding domain-like 2.23e-25
Family cAMP-binding domain 0.000000889
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000438011   Gene: ENSG00000091428   Transcript: ENST00000535187
Sequence length 791
Comment pep:known chromosome:GRCh37:2:173793009:173916706:1 gene:ENSG00000091428 transcript:ENST00000535187 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MIRDRKYHLKTYRQCCVGTELVDWMMQQTPCVHSRTQAVGMWQVLLEDGVLNHVDQEHHF
QDKYLFYRFLDDEHEDAPLPTEEEKKECDEELQDTMLLLSQMGPDAHMRMILRKPPGQRT
VDDLEIIYEELLHIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKG
SVNVVIYGKGVVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRILRDV
EANTVRLKEHDQDVLVLEKVPAGNRASNQGNSQPQQKYTVMSGTPEKILEHFLETIRLEA
TLNEATDSVLNDFIMMHCVFMPNTQLCPALVAHYHAQPSQGTEQEKMDYALNNKRRVIRL
VLQWAAMYGDLLQEDDVSMAFLEEFYVSVSDDARMIAALKEQLPELEKIVKQISEDAKAP
QKKHKVLLQQFNTGDERAQKRQPIRGSDEVLFKVYCMDHTYTTIRVPVATSVKEVISAVA
DKLGSGEGLIIVKMSSGGEKVVLKPNDVSVFTTLTINGRLFACPREQFDSLTPLPEQEGP
TVGTVGTFELMSSKDLAYQMTIYDWELFNCVHELELIYHTFGRHNFKKTTANLDLFLRRF
NEIQFWVVTEICLCSQLSKRVQLLKKFIKIAAHCKEYKNLNSFFAIVMGLSNVAVSRLAL
TWEKLPSKFKKFYAEFESLMDPSRNHRAYRLTVAKLEPPLIPFMPLLIKDMTFTHEGNKT
FIDNLVNFEKMRMIANTARTVRYYRSQPFNPDAAQANKNHQDVRSYVRQLNVIDNQRTLS
QMSHRLEPRRP
Download sequence
Identical sequences A0A2J8PQZ4 B7Z278
ENSP00000438011 NP_001269830.1.87134 NP_001269830.1.92137 ENSP00000438011

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