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Domain assignment for ENSP00000354561 from Homo sapiens 75_37

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000354561
Domain Number 1 Region: 1163-1385
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 8.51e-63
Family DBL homology domain (DH-domain) 0.0000000251
Further Details:      
 
Domain Number 2 Region: 1385-1526
Classification Level Classification E-value
Superfamily PH domain-like 7.08e-31
Family Pleckstrin-homology domain (PH domain) 0.00000142
Further Details:      
 
Domain Number 3 Region: 1540-1660
Classification Level Classification E-value
Superfamily C2 domain (Calcium/lipid-binding domain, CaLB) 2.98e-28
Family PLC-like (P variant) 0.0044
Further Details:      
 
Domain Number 4 Region: 1077-1161
Classification Level Classification E-value
Superfamily SH3-domain 2.89e-27
Family SH3-domain 0.00000321
Further Details:      
 
Domain Number 5 Region: 230-332
Classification Level Classification E-value
Superfamily EF-hand 4.29e-27
Family Eps15 homology domain (EH domain) 0.0028
Further Details:      
 
Domain Number 6 Region: 8-107
Classification Level Classification E-value
Superfamily EF-hand 6.23e-26
Family Eps15 homology domain (EH domain) 0.0019
Further Details:      
 
Domain Number 7 Region: 731-814
Classification Level Classification E-value
Superfamily SH3-domain 2.89e-21
Family SH3-domain 0.00000526
Further Details:      
 
Domain Number 8 Region: 842-931
Classification Level Classification E-value
Superfamily SH3-domain 3.54e-19
Family SH3-domain 0.0000161
Further Details:      
 
Domain Number 9 Region: 953-1014
Classification Level Classification E-value
Superfamily SH3-domain 6.04e-19
Family SH3-domain 0.0000294
Further Details:      
 
Domain Number 10 Region: 1022-1092
Classification Level Classification E-value
Superfamily SH3-domain 0.00000000000000108
Family SH3-domain 0.0000201
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000354561   Gene: ENSG00000198399   Transcript: ENST00000361999
Sequence length 1670
Comment pep:known chromosome:GRCh37:2:24425733:24583178:-1 gene:ENSG00000198399 transcript:ENST00000361999 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MMAQFPTAMNGGPNMWAITSEERTKHDRQFDNLKPSGGYITGDQARNFFLQSGLPAPVLA
EIWALSDLNKDGKMDQQEFSIAMKLIKLKLQGQQLPVVLPPIMKQPPMFSPLISARFGMG
SMPNLSIPQPLPPAAPITSLSSATSGTNLPPLMMPTPLVPSVSTSSLPNGTASLIQPLPI
PYSSSTLPHGSSYSLMMGGFGGASIQKAQSLIDLGSSSSTSSTASLSGNSPKTGTSEWAV
PQPTRLKYRQKFNTLDKSMSGYLSGFQARNALLQSNLSQTQLATIWTLADVDGDGQLKAE
EFILAMHLTDMAKAGQPLPLTLPPELVPPSFRGGKQIDSINGTLPSYQKMQEEEPQKKLP
VTFEDKRKANYERGNMELEKRRQALMEQQQREAERKAQKEKEEWERKQRELQEQEWKKQL
ELEKRLEKQRELERQREEERRKDIERREAAKQELERQRRLEWERIRRQELLNQKNREQEE
IVRLNSKKKNLHLELEALNGKHQQISGRLQDVRLKKQTQKTELEVLDKQCDLEIMEIKQL
QQELQEYQNKLIYLVPEKQLLNERIKNMQFSNTPDSGVSLLHKKSLEKEELCQRLKEQLD
ALEKETASKLSEMDSFNNQLKELRETYNTQQLALEQLYKIKRDKLKEIERKRLELMQKKK
LEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLK
AEEKKRETASVLVNYRALYPFEARNHDEMSFNSGDIIQVDEKTVGEPGWLYGSFQGNFGW
FPCNYVEKMPSSENEKAVSPKKALLPPTVSLSATSTSSEPLSSNQPASVTDYQNVSFSNL
TVNTSWQKKSAFTRTVSPGSVSPIHGQGQVVENLKAQALCSWTAKKDNHLNFSKHDIITV
LEQQENWWFGEVHGGRGWFPKSYVKIIPGSEVKREEPEALYAAVNKKPTSAAYSVGEEYI
ALYPYSSVEPGDLTFTEGEEILVTQKDGEWWTGSIGDRSGIFPSNYVKPKDQESFGSASK
SGASNKKPEIAQVTSAYVASGSEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWF
PASHVKLLGPSSERATPAFHPVCQVIAMYDYAANNEDELSFSKGQLINVMNKDDPDWWQG
EINGVTGLFPSNYVKMTTDSDPSQQWCADLQTLDTMQPIERKRQGYIHELIQTEERYMAD
LQLVVEVFQKRMAESGFLTEGEMALIFVNWKELIMSNTKLLKALRVRKKTGGEKMPVQMI
GDILAAELSHMQAYIRFCSCQLNGAALLQQKTDEDTDFKEFLKKLASDPRCKGMPLSSFL
LKPMQRITRYPLLIRSILENTPESHADHSSLKLALERAEELCSQVNEGVREKENSDRLEW
IQAHVQCEGLAEQLIFNSLTNCLGPRKLLHSGKLYKTKSNKELHGFLFNDFLLLTYMVKQ
FAVSSGSEKLFSSKSNAQFKMYKTPIFLNEVLVKLPTDPSSDEPVFHISHIDRVYTLRTD
NINERTAWVQKIKAASEQYIDTEKKKREKAYQARSQKTSGIGRLMVHVIEATELKACKPN
GKSNPYCEISMGSQSYTTRTIQDTLNPKWNFNCQFFIKDLYQDVLCLTLFDRDQFSPDDF
LGRTEIPVAKIRTEQESKGPMTRRLLLHEVPTGEVWVRFDLQLFEQKTLL
Download sequence
Identical sequences ENSP00000354561 NP_062541.3.87134 NP_062541.3.92137 ENSP00000354561 gi|194294523|ref|NP_062541.3|

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