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Domain assignment for ENSP00000405639 from Homo sapiens 75_37

Domain architecture


Domain assignment details

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Strong hits

Sequence:  ENSP00000405639
Domain Number 1 Region: 592-781
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 1.44e-53
Family DBL homology domain (DH-domain) 0.00000000721
Further Details:      
 
Domain Number 2 Region: 786-926
Classification Level Classification E-value
Superfamily PH domain-like 5.63e-39
Family Pleckstrin-homology domain (PH domain) 0.000000125
Further Details:      
 
Domain Number 3 Region: 272-422
Classification Level Classification E-value
Superfamily Spectrin repeat 1.03e-17
Family Spectrin repeat 0.0029
Further Details:      
 
Domain Number 4 Region: 1025-1081
Classification Level Classification E-value
Superfamily SH3-domain 0.00000000000945
Family SH3-domain 0.0012
Further Details:      
 
Domain Number 5 Region: 39-193
Classification Level Classification E-value
Superfamily CRAL/TRIO domain 0.0000497
Family CRAL/TRIO domain 0.0097
Further Details:      
 
Weak hits

Sequence:  ENSP00000405639
Domain Number - Region: 429-523
Classification Level Classification E-value
Superfamily Spectrin repeat 0.0317
Family Spectrin repeat 0.0078
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) Protein: ENSP00000405639   Gene: ENSG00000126217   Transcript: ENST00000423482
Sequence length 1123
Comment pep:known chromosome:GRCh37:13:113656031:113751224:1 gene:ENSG00000126217 transcript:ENST00000423482 gene_biotype:protein_coding transcript_biotype:protein_coding
Sequence
MTVRRLSLLCRDLWALWLLLKAGADEIMHQDIVPLCAADIQDQLKKRFAYLSGGRGQDGS
PVITFPDYPAFSEIPDKEFQNVMTYLTSIPSLQDAGIGFILVIDRRRDKWTSVKASVLRI
AASFPANLQLVLVLRPTGFFQRTLSDIAFKFNRDDFKMKVPVIMLSSVPDLHGYIDKSQL
TEDLGGTLDYCHSRWLCQRTAIESFALMVKQTAQMLQSFGTELAETELPNDVQSTSSVLC
AHTEKKDKAKEDLRLALKEGHSVLESLRELQAEGSEPSVNQDQLDNQATVQRLLAQLNET
EAAFDEFWAKHQQKLEQCLQLRHFEQGFREVKAILDAASQKIATFTDIGNSLAHVEHLLR
DLASFEEKSGVAVERARALSLDGEQLIGNKHYAVDSIRPKCQELRHLCDQFSAEIARRRG
LLSKSLELHRRLETSMKWCDEGIYLLASQPVDKCQSQDGAEAALQEIEKFLETGAENKIQ
ELNAIYKEYESILNQDLMEHVRKVFQKQASMEEVFHRRQASLKKLAARQTRPVQPVAPRP
EALAKSPCPSPGIRRGSENSSSEGGALRRGPYRRAKSEMSESRQGRGSAGEEEESLAILR
RHVMSELLDTERAYVEELLCVLEGYAAEMDNPLMAHLLSTGLHNKKDVLFGNMEEIYHFH
NRIFLRELENYTDCPELVGRCFLERMEDFQIYEKYCQNKPRSESLWRQCSDCPFFQECQR
KLDHKLSLDSYLLKPVQRITKYQLLLKEMLKYSRNCEGAEDLQEALSSILGILKAVNDSM
HLIAITGYDGNLGDLGKLLMQGSFSVWTDHKRGHTKVKELARFKPMQRHLFLHEKAVLFC
KKREENGEGYEKAPSYSYKQSLNMAAVGITENVKGDAKKFEIWYNAREEVYIVQAPTPEI
KAAWVNEIRKVLTSQLQACREASQHRALEQSQSLPLPAPTSTSPSRGNSRNIKKLEERKT
DPLSLEGYVSSAPLTKPPEKGKGWSKTSHSLEAPEDDGGWSSAEEQINSSDAEEDGGLGP
KKLVPGKYTVVADHEKGGPDALRVRSGDVVELVQEGDEGLWYVRDPTTGKEGWVPASSLS
VRLGPSGSAQCLSSSESSPGSAVLSNSSSCSEGGQAPFSDLQG
Download sequence
Identical sequences ENSP00000364754 NP_079255.4.87134 NP_079255.4.92137 ENSP00000405639 gi|339276002|ref|NP_079255.4|

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