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  Home > Genomes > NCBI 2017_08 genome > NP_003117.2.87134

Domain assignment for NP_003117.2.87134 from NCBI 2017_08 genome

Domain architecture

Domain assignment details

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Strong hits

Sequence:  NP_003117.2.87134
Domain Number 1 Region: 424-579
Classification Level Classification E-value
Superfamily Spectrin repeat 3.93e-33
Family Spectrin repeat 0.00026
Further Details:      
 
Domain Number 2 Region: 636-789
Classification Level Classification E-value
Superfamily Spectrin repeat 9.17e-32
Family Spectrin repeat 0.00048
Further Details:      
 
Domain Number 3 Region: 318-468
Classification Level Classification E-value
Superfamily Spectrin repeat 1.44e-31
Family Spectrin repeat 0.00078
Further Details:      
 
Domain Number 4 Region: 217-367
Classification Level Classification E-value
Superfamily Spectrin repeat 1.83e-31
Family Spectrin repeat 0.00051
Further Details:      
 
Domain Number 5 Region: 1449-1603
Classification Level Classification E-value
Superfamily Spectrin repeat 9.16e-29
Family Spectrin repeat 0.00019
Further Details:      
 
Domain Number 6 Region: 756-896
Classification Level Classification E-value
Superfamily Spectrin repeat 1.32e-28
Family Spectrin repeat 0.00062
Further Details:      
 
Domain Number 7 Region: 1713-1819
Classification Level Classification E-value
Superfamily Spectrin repeat 2.49e-27
Family Spectrin repeat 0.00000822
Further Details:      
 
Domain Number 8 Region: 1343-1496
Classification Level Classification E-value
Superfamily Spectrin repeat 3.14e-27
Family Spectrin repeat 0.00012
Further Details:      
 
Domain Number 9 Region: 124-261
Classification Level Classification E-value
Superfamily Spectrin repeat 1.83e-26
Family Spectrin repeat 0.0018
Further Details:      
 
Domain Number 10 Region: 1237-1380
Classification Level Classification E-value
Superfamily Spectrin repeat 3.93e-26
Family Spectrin repeat 0.0015
Further Details:      
 
Domain Number 11 Region: 1767-1926
Classification Level Classification E-value
Superfamily Spectrin repeat 4.32e-26
Family Spectrin repeat 0.0000926
Further Details:      
 
Domain Number 12 Region: 19-154
Classification Level Classification E-value
Superfamily Spectrin repeat 6.7e-25
Family Spectrin repeat 0.000000126
Further Details:      
 
Domain Number 13 Region: 2038-2150
Classification Level Classification E-value
Superfamily Spectrin repeat 7.2e-24
Family Spectrin repeat 0.00067
Further Details:      
 
Domain Number 14 Region: 1575-1695
Classification Level Classification E-value
Superfamily Spectrin repeat 5.1e-23
Family Spectrin repeat 0.0000665
Further Details:      
 
Domain Number 15 Region: 977-1058
Classification Level Classification E-value
Superfamily SH3-domain 1.29e-19
Family SH3-domain 0.00012
Further Details:      
 
Domain Number 16 Region: 900-964,1042-1080
Classification Level Classification E-value
Superfamily Spectrin repeat 1.35e-18
Family Spectrin repeat 0.0019
Further Details:      
 
Domain Number 17 Region: 1895-2031
Classification Level Classification E-value
Superfamily Spectrin repeat 2.75e-17
Family Spectrin repeat 0.0014
Further Details:      
 
Domain Number 18 Region: 2157-2264
Classification Level Classification E-value
Superfamily Spectrin repeat 8.38e-17
Family Spectrin repeat 0.0048
Further Details:      
 
Domain Number 19 Region: 2266-2416
Classification Level Classification E-value
Superfamily EF-hand 3.31e-16
Family Calmodulin-like 0.012
Further Details:      
 
Domain Number 20 Region: 1088-1182
Classification Level Classification E-value
Superfamily Spectrin repeat 0.000000000000327
Family Spectrin repeat 0.0017
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score

Protein sequence

External link(s) NP_003117.2.87134
Sequence length 2419
Comment spectrin alpha chain, erythrocytic 1 [Homo sapiens]; AA=GCF_000306695.2; RF=na; TAX=9606; STAX=9606; NAME=Homo sapiens; AL=Chromosome; RT=Major
Sequence 
MEQFPKETVVESSGPKVLETAEEIQERRQEVLTRYQSFKERVAERGQKLEDSYHLQVFKR
DADDLGKWIMEKVNILTDKSYEDPTNIQGKYQKHQSLEAEVQTKSRLMSELEKTREERFT
MGHSAHEETKAHIEELRHLWDLLLELTLEKGDQLLRALKFQQYVQECADILEWIGDKEAI
ATSVELGEDWERTEVLHKKFEDFQVELVAKEGRVVEVNQYANECAEENHPDLPLIQSKQN
EVNAAWERLRGLALQRQKALSNAANLQRFKRDVTEAIQWIKEKEPVLTSEDYGKDLVASE
GLFHSHKGLERNLAVMSDKVKELCAKAEKLTLSHPSDAPQIQEMKEDLVSSWEHIRALAT
SRYEKLQATYWYHRFSSDFDELSGWMNEKTAAINADELPTDVAGGEVLLDRHQQHKHEID
SYDDRFQSADETGQDLVNANHEASDEVREKMEILDNNWTALLELWDERHRQYEQCLDFHL
FYRDSEQVDSWMSRQEAFLENEDLGNSLGSAEALLQKHEDFEEAFTAQEEKIITVDKTAT
KLIGDDHYDSENIKAIRDGLLARRDALREKAATRRRLLKESLLLQKLYEDSDDLKNWINK
KKKLADDEDYKDIQNLKSRVQKQQVFEKELAVNKTQLENIQKTGQEMIEGGHYASDNVTT
RLSEVASLWEELLEATKQKGTQLHEANQQLQFENNAEDLQRWLEDVEWQVTSEDYGKGLA
EVQNRLRKHGLLESAVAARQDQVDILTDLAAYFEEIGHPDSKDIRARQESLVCRFEALKE
PLATRKKKLLDLLHLQLICRDTEDEEAWIQETEPSATSTYLGKDLIASKKLLNRHRVILE
NIASHEPRIQEITERGNKMVEEGHFAAEDVASRVKSLNQNMESLRARAARRQNDLEANVQ
FQQYLADLHEAETWIREKEPIVDNTNYGADEEAAGALLKKHEAFLLDLNSFGDSMKALRN
QANACQQQQAAPVEGVAGEQRVMALYDFQARSPREVTMKKGDVLTLLSSINKDWWKVEAA
DHQGIVPAVYVRRLAHDEFPMLPQRRREEPGNITQRQEQIENQYRSLLDRAEERRRRLLQ
RYNEFLLAYEAGDMLEWIQEKKAENTGVELDDVWELQKKFDEFQKDLNTNEPRLRDINKV
ADDLLFEGLLTPEGAQIRQELNSRWGSLQRLADEQRQLLGSAHAVEVFHREADDTKEQIE
KKCQALSAADPGSDLFSVQALQRRHEGFERDLVPLGDKVTILGETAERLSESHPDATEDL
QRQKMELNEAWEDLQGRTKDRKESLNEAQKFYLFLSKARDLQNWISSIGGMVSSQELAED
LTGIEILLERHQEHRADMEAEAPTFQALEDFSAELIDSGHHASPEIEKKLQAVKLERDDL
EKAWEKRKKILDQCLELQMFQGNCDQVESWMVARENSLRSDDKSSLDSLEALMKKRDDLD
KAITAQEGKITDLEHFAESLIADEHYAKEEIATRLQRVLDRWKALKAQLIDERTKLGDYA
NLKQFYRDLEELEEWISEMLPTACDESYKDATNIQRKYLKHQTFAHEVDGRSEQVHGVIN
LGNSLIECSACDGNEEAMKEQLEQLKEHWDHLLERTNDKGKKLNEASRQQRFNTSIRDFE
FWLSEAETLLAMKDQARDLASAGNLLKKHQLLEREMLAREDALKDLNTLAEDLLSSGTFN
VDQIVKKKDNVNKRFLNVQELAAAHHEKLKEAYALFQFFQDLDDEESWIEEKLIRVSSQD
YGRDLQGVQNLLKKHKRLEGELVAHEPAIQNVLDMAEKLKDKAAVGQEEIQLRLAQFVEH
WEKLKELAKARGLKLEESLEYLQFMQNAEEEEAWINEKNALAVRGDCGDTLAATQSLLMK
HEALENDFAVHETRVQNVCAQGEDILNKVLQEESQNKEISSKIEALNEKTPSLAKAIAAW
KLQLEDDYAFQEFNWKADVVEAWIADKETSLKTNGNGADLGDFLTLLAKQDTLDASLQSF
QQERLPEITDLKDKLISAQHNQSKAIEERYAALLKRWEQLLEASAVHRQKLLEKQLPLQK
AEDLFVEFAHKASALNNWCEKMEENLSEPVHCVSLNEIRQLQKDHEDFLASLARAQADFK
CLLELDQQIKALGVPSSPYTWLTVEVLERTWKHLSDIIEEREQELQKEEARQVKNFEMCQ
EFEQNASTFLQWILETRAYFLDGSLLKETGTLESQLEANKRKQKEIQAMKRQLTKIVDLG
DNLEDALILDIKYSTIGLAQQWDQLYQLGLRMQHNLEQQIQAKDIKGVSEETLKEFSTIY
KHFDENLTGRLTHKEFRSCLRGLNYYLPMVEEDEHEPKFEKFLDAVDPGRKGYVSLEDYT
AFLIDKESENIKSSDEIENAFQALAEGKSYITKEDMKQALTPEQVSFCATHMQQYMDPRG
RSHLSGYDYVGFTNSYFGN
Download sequence
Identical sequences P02549
ENSP00000357129 ENSP00000357129 ENSP00000357129 9606.ENSP00000357130 gi|115298659|ref|NP_003117.2| NP_003117.2.87134 NP_003117.2.92137 XP_011508218.1.92137

Jump to [ Top of page · Domain architecture · Domain assignment details · Most Informative Gene Ontologies ]
Please cite: Gough, J., Karplus, K., Hughey, R. and Chothia, C. (2001). "Assignment of Homology to Genome Sequences using a Library of Hidden Markov Models that Represent all Proteins of Known Structure." J. Mol. Biol., 313(4), 903-919.

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© Copyright 2013 The SUPERFAMILY authors and Julian Gough.