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Domain assignment for NP_945328.1.87134 from NCBI 2017_08 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  NP_945328.1.87134
Domain Number 1 Region: 363-591
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 9.03e-61
Family DBL homology domain (DH-domain) 0.000000601
Further Details:      
 
Domain Number 2 Region: 44-200
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 1.77e-54
Family Regulator of G-protein signaling, RGS 0.0000000592
Further Details:      
 
Domain Number 3 Region: 592-726
Classification Level Classification E-value
Superfamily PH domain-like 2.36e-38
Family Pleckstrin-homology domain (PH domain) 0.0000226
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) NP_945328.1.87134
Sequence length 879
Comment rho guanine nucleotide exchange factor 1 isoform 3 [Homo sapiens]; AA=GCF_000306695.2; RF=na; TAX=9606; STAX=9606; NAME=Homo sapiens; AL=Chromosome; RT=Major
Sequence
MEDFARGAASPGPSRPGLVPVSIIGAEDEDFENELETNSEEQNSQFQSLEQVKRRPAHLM
ALLQHVALQFEPGPLVLRVPVPPNVAFELDRTRADLISEDVQRRFVQEVVQSQQVAVGRQ
LEDFRSKRLMGMTPWEQELAQLEAWVGRDRASYEARERHVAERLLMHLEEMQHTISTDEE
KSAAVVNAIGLYMRHLGVRTKSGDKKSGRNFFRKKVMGNRRSDEPAKTKKGLSSILDAAR
WNRGEPQVPDFRHLKAEVDAEKPGATDRKGGVGMPSRDRNIGAPGQDTPGVSLHPLSLDS
PDREPGADAPLELGDSSPQGPMSLESLAPPESTDEGAETESPEPGDEGEPGRSGLELEPE
EPPGWRELVPPDTLHSLPKSQVKRQEVISELLVTEAAHVRMLRVLHDLFFQPMAECLFFP
LEELQNIFPSLDELIEVHSLFLDRLMKRRQESGYLIEEIGDVLLARFDGAEGSWFQKISS
RFCSRQSFALEQLKAKQRKDPRFCAFVQEAESRPRCRRLQLKDMIPTEMQRLTKYPLLLQ
SIGQNTEEPTEREKVELAAECCREILHHVNQAVRDMEDLLRLKDYQRRLDLSHLRQSSDP
MLSEFKNLDITKKKLVHEGPLTWRVTKDKAVEVHVLLLDDLLLLLQRQDERLLLKSHSRT
LTPTPDGKTMLRPVLRLTSAMTREVATDHKAFYVLFTWDQEAQIYELVAQTVSERKNWCA
LITETAGSLKVPAPASRPKPRPSPSSTREPLLSSSENGNGGRETSPADARTERILSDLLP
FCRPGPEGQLAATALRKVLSLKQLLFPAEEDNGAGPPRDGDGVPGGGPLSPARTQEIQEN
LLSLEETMKQLEELEEEFCRLRPLLSQLGGNSVPQPGCT
Download sequence
Identical sequences ENSP00000344429 ENSP00000344429 gi|39777604|ref|NP_945328.1| NP_945328.1.87134 NP_945328.1.92137

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