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Domain assignment for A0A0I8XR24 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A0I8XR24
Domain Number 1 Region: 5-117,225-423
Classification Level Classification E-value
Superfamily Substrate-binding domain of HMG-CoA reductase 5.36e-103
Family Substrate-binding domain of HMG-CoA reductase 0.00000165
Further Details:      
 
Domain Number 2 Region: 110-216
Classification Level Classification E-value
Superfamily NAD-binding domain of HMG-CoA reductase 2.88e-32
Family NAD-binding domain of HMG-CoA reductase 0.00038
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) A0A0I8XR24
Sequence length 424
Comment (tr|A0A0I8XR24|A0A0I8XR24_STREE) 3-hydroxy-3-methylglutaryl coenzyme A reductase {ECO:0000256|RuleBase:RU361219} KW=Complete proteome OX=1313 OS=Streptococcus pneumoniae. GN=ERS020535_00461 OC=Streptococcus.
Sequence
MKISWNGFSKKSYQERLELLKAQALLSPERQASLEKDEQMSVTVADQLSENVVGTFSLPY
SLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQVHQRQMIGQVALYQIA
NPKLAQEKIASKKAELLELANQAYPSIVKRGGGASDLHVEQIKGEPDFLVVYIHVDTQEA
MGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTASCRMAFRYLSRQKDQGREI
AEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGL
SCWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVALSHDLLGNPSARELAQIIVSIGLA
QNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAPLVERLISDKTFNLETAQRYLE
NLRS
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Identical sequences A0A0I8XR24
WP_000704379.1.100325 WP_000704379.1.11474 WP_000704379.1.11861 WP_000704379.1.12198 WP_000704379.1.12570 WP_000704379.1.12595 WP_000704379.1.13330 WP_000704379.1.13340 WP_000704379.1.13537 WP_000704379.1.14404 WP_000704379.1.14900 WP_000704379.1.15026 WP_000704379.1.1515 WP_000704379.1.15967 WP_000704379.1.16101 WP_000704379.1.16385 WP_000704379.1.16902 WP_000704379.1.16981 WP_000704379.1.1714 WP_000704379.1.17411 WP_000704379.1.18193 WP_000704379.1.18884 WP_000704379.1.19754 WP_000704379.1.20396 WP_000704379.1.21271 WP_000704379.1.21642 WP_000704379.1.23180 WP_000704379.1.24466 WP_000704379.1.25155 WP_000704379.1.2629 WP_000704379.1.26447 WP_000704379.1.26544 WP_000704379.1.26818 WP_000704379.1.26918 WP_000704379.1.27007 WP_000704379.1.27071 WP_000704379.1.28524 WP_000704379.1.28574 WP_000704379.1.28709 WP_000704379.1.29039 WP_000704379.1.29204 WP_000704379.1.2951 WP_000704379.1.29572 WP_000704379.1.29730 WP_000704379.1.30923 WP_000704379.1.30982 WP_000704379.1.3178 WP_000704379.1.32906 WP_000704379.1.34772 WP_000704379.1.34973 WP_000704379.1.35406 WP_000704379.1.3646 WP_000704379.1.37858 WP_000704379.1.38429 WP_000704379.1.38765 WP_000704379.1.38825 WP_000704379.1.38851 WP_000704379.1.38957 WP_000704379.1.39412 WP_000704379.1.39443 WP_000704379.1.39533 WP_000704379.1.39596 WP_000704379.1.40117 WP_000704379.1.40400 WP_000704379.1.40733 WP_000704379.1.41267 WP_000704379.1.41278 WP_000704379.1.41757 WP_000704379.1.42030 WP_000704379.1.43347 WP_000704379.1.44356 WP_000704379.1.44498 WP_000704379.1.45087 WP_000704379.1.45118 WP_000704379.1.45917 WP_000704379.1.46874 WP_000704379.1.46878 WP_000704379.1.46934 WP_000704379.1.4707 WP_000704379.1.47633 WP_000704379.1.48468 WP_000704379.1.48767 WP_000704379.1.4933 WP_000704379.1.49904 WP_000704379.1.50489 WP_000704379.1.50530 WP_000704379.1.52157 WP_000704379.1.53340 WP_000704379.1.53820 WP_000704379.1.54473 WP_000704379.1.54971 WP_000704379.1.55677 WP_000704379.1.56112 WP_000704379.1.57004 WP_000704379.1.5710 WP_000704379.1.58697 WP_000704379.1.58811 WP_000704379.1.58877 WP_000704379.1.59589 WP_000704379.1.61043 WP_000704379.1.61214 WP_000704379.1.61278 WP_000704379.1.61405 WP_000704379.1.61801 WP_000704379.1.61807 WP_000704379.1.62434 WP_000704379.1.6288 WP_000704379.1.63741 WP_000704379.1.64756 WP_000704379.1.64782 WP_000704379.1.65319 WP_000704379.1.65887 WP_000704379.1.65960 WP_000704379.1.66046 WP_000704379.1.66688 WP_000704379.1.67761 WP_000704379.1.68661 WP_000704379.1.68671 WP_000704379.1.68853 WP_000704379.1.69065 WP_000704379.1.70279 WP_000704379.1.70436 WP_000704379.1.70528 WP_000704379.1.70828 WP_000704379.1.7126 WP_000704379.1.71685 WP_000704379.1.72421 WP_000704379.1.7262 WP_000704379.1.73336 WP_000704379.1.73979 WP_000704379.1.74385 WP_000704379.1.76570 WP_000704379.1.77534 WP_000704379.1.77663 WP_000704379.1.77906 WP_000704379.1.78191 WP_000704379.1.78275 WP_000704379.1.79298 WP_000704379.1.79693 WP_000704379.1.80449 WP_000704379.1.80875 WP_000704379.1.81190 WP_000704379.1.8154 WP_000704379.1.81628 WP_000704379.1.81807 WP_000704379.1.82049 WP_000704379.1.8248 WP_000704379.1.82793 WP_000704379.1.83432 WP_000704379.1.83899 WP_000704379.1.84214 WP_000704379.1.85064 WP_000704379.1.85111 WP_000704379.1.85418 WP_000704379.1.8547 WP_000704379.1.85526 WP_000704379.1.85625 WP_000704379.1.86772 WP_000704379.1.89708 WP_000704379.1.89843 WP_000704379.1.90062 WP_000704379.1.91034 WP_000704379.1.91078 WP_000704379.1.92381 WP_000704379.1.9326 WP_000704379.1.93274 WP_000704379.1.9348 WP_000704379.1.93595 WP_000704379.1.94092 WP_000704379.1.94159 WP_000704379.1.94192 WP_000704379.1.94559 WP_000704379.1.94954 WP_000704379.1.96117 WP_000704379.1.96244 WP_000704379.1.9632 WP_000704379.1.96432 WP_000704379.1.96772 WP_000704379.1.971 WP_000704379.1.97182 WP_000704379.1.97354 WP_000704379.1.9806 WP_000704379.1.9819 WP_000704379.1.98467 WP_000704379.1.98943 WP_000704379.1.99001 WP_000704379.1.99309

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