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Domain assignment for A0A0M4KEJ4 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A0M4KEJ4
Domain Number 1 Region: 5-117,225-423
Classification Level Classification E-value
Superfamily Substrate-binding domain of HMG-CoA reductase 6.93e-103
Family Substrate-binding domain of HMG-CoA reductase 0.00000159
Further Details:      
 
Domain Number 2 Region: 110-216
Classification Level Classification E-value
Superfamily NAD-binding domain of HMG-CoA reductase 1.06e-33
Family NAD-binding domain of HMG-CoA reductase 0.00031
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) A0A0M4KEJ4
Sequence length 424
Comment (tr|A0A0M4KEJ4|A0A0M4KEJ4_STRMT) 3-hydroxy-3-methylglutaryl coenzyme A reductase {ECO:0000256|RuleBase:RU361219} KW=Complete proteome OX=28037 OS=Streptococcus mitis. GN=RN80_04060 OC=Streptococcus.
Sequence
MKISWNGFSKKSYQERLELLKAQALLSPEKQTSLEQDEQISVTVADQLSENVVGTFSLPY
SLVPEVLVNGQEYTVPYVTEEPSVVAAASYASKIIKRAGGFTAQVHERQMIGQVALYQVA
NPEQAQEKIASKKAELLELANQAYPSIVKRGGGARDLHVEQIKGETDFLVVYLHVDTQEA
MGANMLNTMLEALKPVLEELSQGQSLMGILSNYATDSLVTASCRIAFRYLSRQKDQGREI
AEKIALASQFAQADPYRAATHNKGIFNGIDAILIATGNDWRAIEAGAHAFASRDGRYQGL
SRWTLDLEREELVGEMTLPMPVATKGGSIGLNPRVAISHELLGNPSAKELAQIIVSIGLA
QNFAALKALVSTGIQQGHMKLQAKSLALLAGASESEVAPLVERLIADKTFNLETAQRYLE
NLRS
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Identical sequences A0A0M4KEJ4
WP_060627676.1.71029

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