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Domain assignment for H2T0L4 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  H2T0L4
Domain Number 1 Region: 415-710
Classification Level Classification E-value
Superfamily Protein kinase-like (PK-like) 1.62e-77
Family Protein kinases, catalytic subunit 0.000000000387
Further Details:      
 
Domain Number 2 Region: 894-1031
Classification Level Classification E-value
Superfamily FAT domain of focal adhesion kinase 6.15e-57
Family FAT domain of focal adhesion kinase 0.000000353
Further Details:      
 
Domain Number 3 Region: 134-256
Classification Level Classification E-value
Superfamily Second domain of FERM 5.63e-41
Family Second domain of FERM 0.00000168
Further Details:      
 
Domain Number 4 Region: 34-133
Classification Level Classification E-value
Superfamily Ubiquitin-like 1.03e-35
Family First domain of FERM 0.0000213
Further Details:      
 
Domain Number 5 Region: 257-365
Classification Level Classification E-value
Superfamily PH domain-like 6.52e-35
Family Third domain of FERM 0.00000551
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) H2T0L4
Sequence length 1032
Comment (tr|H2T0L4|H2T0L4_TAKRU) Protein tyrosine kinase 2 {ECO:0000313|Ensembl:ENSTRUP00000018202} KW=Complete proteome; Reference proteome OX=31033 OS=Takifugu rubripes (Japanese pufferfish) (Fugu rubripes). GN=PTK2 OC=Takifugu.
Sequence
MATAYLDPNLNHAFLGGAKSRLSAGGSDRTVAGSVDRVLKVFHHFETNTEQNFWSSNIRY
GDATDVRGIIQKILDIHKVRFTSCFGLRLSNSQFRDQVHWLHPEMGVSHVREKYEQARPT
EEWRYELRIRYLPKSFVQQFSEDKPTLSYFYHQVKNDYMTEIGDQVDQDVALKLGCLEIR
RFFKEMRGNALDKKSNYELLEKDVGLRRFFPKALLDSVKAKTLRKLIQQTFKQVANLNDE
QCILKFLDILAPICRYDKECFKCALGSSWVIQVELAIGPEEGISYLTDKGSTPTHLANFN
QVQSIQYSAMEEKDRKGMIQLNVAGAAEPLTVTTALLTTAENLADLIDGYCRLISMESHS
FIVRVHKEGERALPSIPKVSNHEKKLEAVRSGSVCPVTETDDYAEIVDEEDTYTMPSTRD
YEIQRDRIELGRCIGEGQFGDVHQGVYNSPDKPALHVAIKTCKNCTSDSVREKFLQEALT
MRQFDHPHIVKLIGVITENPVWIIMELCTLGELRSFLQVRKYSLDLATLILFAYQLSTAL
AYLESKRFVHRDIAARNVLVSSVDCVMLGDFGLSRYMEDSSYYKASKGKLPIKWMAPESI
NFRRFTSASDVWMFGGVCMWEILMYGIKPFQGVKNNDVIGRIENGERLAMPPQCPPTLYS
LMTKCWSYDPSKRPRFTELKTQLSTILEEEKLQEEERHRMEMRRQVNMSWDSGGSDEAPP
KPSRPGYPSPRSSEGFFPSPQLNHFQPSAHAGGGGGVGGSFTPTDSWSQHRSEHTAMWSP
NIEHQCSVQGNGQAQMEERLMMQQQQMEDDQRWLEQEESFMYMKTESRNSRGSIDREDGT
LQAPSGSQHIYQPIGKPEPVAPPKKPPRPGAPCHLANLGPVESYNEGVKLQPQEISPTPT
ANLDRSNDKVYENVTGLVKAVIEMSNRIQPAAPEEYVPMVKEVGLALRTLLATVDETLPV
LPASTHREIEMAQKLLNSDLAELISKMKLAQQYVMTSLQKDYKKHMLMAAHALAVDAKNL
LDVIDQSRLKMI
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Identical sequences H2T0L4
ENSTRUP00000018202

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