The results are sorted from lowest E-value to highest E-value. Strong classifications have a low E-value. Weak classifications have an E-value greater than 0.0001. Weak hits are shown in gray. Weak hits are not shown on the domain architecture.
The family level classification is conditional on the domain being a member of the specified superfamily. There is a possibility that the selected domain is a member of a sub-family for which no structure has yet been solved.
| Sequence: |
I1TMH0 |
| Domain Number 1 |
Region: 3332-3632 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Trypsin-like serine proteases |
1.71e-137 |
| Family |
Viral cysteine protease of trypsin fold |
0.000000101 |
| Further Details: |
|
| |
| Domain Number 2 |
Region: 6504-6691 |
| Classification Level |
Classification |
E-value |
| Superfamily |
S-adenosyl-L-methionine-dependent methyltransferases |
3.99e-74 |
| Family |
Nsp15 N-terminal domain-like |
0.00000000678 |
| Further Details: |
|
| |
| Domain Number 3 |
Region: 6722-6872 |
| Classification Level |
Classification |
E-value |
| Superfamily |
EndoU-like |
1.45e-60 |
| Family |
Nsp15 C-terminal domain-like |
0.000000144 |
| Further Details: |
|
| |
| Domain Number 4 |
Region: 4049-4198 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Coronavirus NSP8-like |
2.35e-59 |
| Family |
Coronavirus NSP8-like |
0.00000637 |
| Further Details: |
|
| |
| Domain Number 5 |
Region: 4856-5159,5200-5344 |
| Classification Level |
Classification |
E-value |
| Superfamily |
DNA/RNA polymerases |
8.4e-55 |
| Family |
RNA-dependent RNA-polymerase |
0.021 |
| Further Details: |
|
| |
| Domain Number 6 |
Region: 4323-4444 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Coronavirus NSP10-like |
6.15e-52 |
| Family |
Coronavirus NSP10-like |
0.00000674 |
| Further Details: |
|
| |
| Domain Number 7 |
Region: 4210-4317 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Replicase NSP9 |
1.06e-42 |
| Family |
Replicase NSP9 |
0.0001 |
| Further Details: |
|
| |
| Domain Number 8 |
Region: 830-945 |
| Classification Level |
Classification |
E-value |
| Superfamily |
NSP3A-like |
1.06e-37 |
| Family |
NSP3A-like |
0.00036 |
| Further Details: |
|
| |
| Domain Number 9 |
Region: 1318-1474 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Macro domain-like |
4.37e-34 |
| Family |
Macro domain |
0.00018 |
| Further Details: |
|
| |
| Domain Number 10 |
Region: 5656-5962 |
| Classification Level |
Classification |
E-value |
| Superfamily |
P-loop containing nucleoside triphosphate hydrolases |
2.36e-30 |
| Family |
Tandem AAA-ATPase domain |
0.068 |
| Further Details: |
|
| |
| Domain Number 11 |
Region: 3922-4009 |
| Classification Level |
Classification |
E-value |
| Superfamily |
Coronavirus NSP7-like |
7.45e-25 |
| Family |
Coronavirus NSP7-like |
0.00032 |
| Further Details: |
|
| |
| Domain Number 12 |
Region: 980-1163 |
| Classification Level |
Classification |
E-value |
| Superfamily |
S-adenosyl-L-methionine-dependent methyltransferases |
6.15e-24 |
| Family |
Nsp15 N-terminal domain-like |
0.041 |
| Further Details: |
|
| |
The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by 
(show help)
Information Content (IC) is an information theoretic score measured in bits of how informative it is to assign a given ontological term to a domain archtecture. The higher the score the more informative it is to talk about the term given the domain architecture.
H-score (hypergeometric score) indicates the strength of assigning an ontological term to this domain architecture. Assignments with higher scores are of a better quality. Details for the methodology be found on the dcGO website.
| Cellular Component |
IC (bits) |
H-Score |
| Biological Process |
IC (bits) |
H-Score |
| Molecular Function |
IC (bits) |
H-Score |
