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Domain assignment for A0A2K5X3W4 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  A0A2K5X3W4
Domain Number 1 Region: 691-837
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 1.83e-40
Family Regulator of G-protein signaling, RGS 0.0001
Further Details:      
 
Domain Number 2 Region: 1017-1116
Classification Level Classification E-value
Superfamily Ubiquitin-like 8.06e-30
Family Ras-binding domain, RBD 0.00083
Further Details:      
 
Domain Number 3 Region: 215-372
Classification Level Classification E-value
Superfamily PH domain-like 1.72e-22
Family Phosphotyrosine-binding domain (PTB) 0.013
Further Details:      
 
Domain Number 4 Region: 9-100
Classification Level Classification E-value
Superfamily PDZ domain-like 4.53e-20
Family PDZ domain 0.01
Further Details:      
 
Domain Number 5 Region: 962-1031
Classification Level Classification E-value
Superfamily Ubiquitin-like 0.00000000000000227
Family Ras-binding domain, RBD 0.049
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) A0A2K5X3W4
Sequence length 1447
Comment (tr|A0A2K5X3W4|A0A2K5X3W4_MACFA) Regulator of G protein signaling 12 {ECO:0000313|Ensembl:ENSMFAP00000044167} OX=9541 OS=Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey). GN=RGS12 OC=Catarrhini; Cercopithecidae; Cercopithecinae; Macaca.
Sequence
MFRVGEASKRPLPGPTPPRVRSVEVARGRAGYGFTLSGQAPCVLSCVMRGSPADFVGLRA
GDQIFAVNEINVKKASHEDVVKLIGKCSGVLHMVIAEGIGRLESCSSDEEGGLYEGKGWL
KPKLDSKALGINRAERVVEEMQSGGIFNMIFENPSLCASSSEPLKLKQRSLSESAAARFD
VGHESMNNPNPNMLSKEEISKVIHDDSVFSIGLESHDDFALDASILNVAMIVGYLGSIEL
PSTSSNLESDSLQAIRGCMRRLRAEQKIHSLVTMKIMHDCVQLSTDKAGVVAEYPAEKLA
FSAVCPDDRRFFGLVTMQTNDDGSLAQEEEGALRTSCHVFMVDPDLFNHKIHQGIARRFG
FECTADPDTNGCLEFPASSLPVLQFISVLYRDMGELIEGMRARAFLDGDADAHQNNSTSS
NSDSGIGNFHQEEKSNRVLVVDLGGSSSRHGPGGSAWDGVGGRGTQPWGAPWSGPFCPDS
EGSPPFEAAHQTDRFRDLNKHLGPASPVEVPPASLRSSVPPSKRGTVGASCGFNQRWLPV
HVLREWQCGHASDQESYTDSTDGWSSVNCGTLPPPMSKIPADRYRVEGSFAQPPLSTPKR
EWSRKAFGMQNIFGPHRTVRKTKEDKKGSKFGRGIGLTQPSQRTSARRSFGRSKRFSITR
SLDDLESATVSDGELTGADLKDCISNNSLSSNASLPSVQSCRRLRERRVASWAVSFERLL
QDPVGVRYFSDFLRKEFSEENILFWQACEYFNHVPAHDKKELSYRAREIFSKFLCSKATT
PVNIDSQAQLADDVLRAPHPDMFKEQQLQIFNLMKFDSYTRFLKSPLYQECILAEVEGRA
LPDSQQVPSSPASKHSLGSDQSSVSTPKKLSGKSKSGRSLNEEMGDEDSEKKRKGAFFSW
SRTRSTGRSQKKREHGDHADDPLHANGGLCRRESQGSVSSAGSLDLSEACRTLAPEKDKA
TKHCCIHLPDGTSCVVAVKAGFSIKDILSGLCERHGINGAAADLFLVGGDKPLVLHQDSS
ILESRDLRLEKRTLFRLDLVPINRSVGLKAKPTKPVTEVLRPVVAKYGLDLSGLLVRLSG
EKEPLDLGAPISSLDGQRVVLEEKDPSRGKASTDKQKGVPVKQNIAVNSSSRNHSAMGEE
RTLGKSNSIKIKGENGKNARDPRLSKREESIAKIGKKKYQKINLDEAEEFFELISKAQSN
RADDQRGLLRKEDLVLPEFLRLPPGSTELTLPTAAAMAKGFSKRSATGNGRESASQPSEQ
WEPAQESSDSPSTSPGSVPSPPGPPGTTPPGQKSPSGPFCTPQSPVSLAQEGTTQIWKRQ
SREVEAGGIQTVEDEHVAELTLMGEGDISSPNSTLLPPPSGPQDVPGPSRPESGTHGSRD
LPVNRIIDVDLVTGLAPGQDGGIAGAQAGPGRAQAGGGSPTSDLPGLSPVPGEPVKPKAS
AHHATFV
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Identical sequences A0A2K5X3W4
XP_005554411.1.63531

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