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Domain assignment for D7DC72 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  D7DC72
Domain Number 1 Region: 9-122,226-422
Classification Level Classification E-value
Superfamily Substrate-binding domain of HMG-CoA reductase 6.8e-100
Family Substrate-binding domain of HMG-CoA reductase 0.000000141
Further Details:      
 
Domain Number 2 Region: 115-221
Classification Level Classification E-value
Superfamily NAD-binding domain of HMG-CoA reductase 4.97e-31
Family NAD-binding domain of HMG-CoA reductase 0.0000443
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Biological Process IC (bits) H-Score
Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score

Protein sequence

External link(s) D7DC72
Sequence length 428
Comment (tr|D7DC72|D7DC72_STAHD) 3-hydroxy-3-methylglutaryl coenzyme A reductase {ECO:0000256|RuleBase:RU361219} KW=Complete proteome OX=591019 OS=BK20S6-10-b1 / P8). GN=Shell_0645 OC=Desulfurococcaceae; Staphylothermus.
Sequence
MSHEMRSSRIPGFYKKSLDERLRIVGEWAGLTEEEVNLLRNLGNLPEKIADSMIENVIGG
MTYPFAVAVNFKINGRDYLVPMVIEETSVVAAASNAAKMLRRGRGIIVRAGPQEMIGQIH
LVNVEAPYYKAMKILEHKEEIIDHAKQQDSTLIKLGGGPRDLEVRVLNTRMGPVIVVHLI
VDVLDAMGANAVNTMVESIAPLLEKITGGEARLRIISNYATRRIVRALARTDPEDVGGKD
VARKIVEASILAEADPYRAVTHNKGIMNGIIAVALATAQDHRAIEAGAHAYAARSGVYKP
LSTWELDEEGMLVGSLELPLQVGIVGGATKVHPIAKIALKILGVKTAKELAEIMAAVGLA
QNLAALRALVHEGIQKGHMRLHARNLAIMAGATGELIDKIAERMIGEGKIRYDYAKKLLE
EYLKGENK
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Identical sequences D7DC72
gi|297526644|ref|YP_003668668.1|

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