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Domain assignment for E7EZS3 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  E7EZS3
Domain Number 1 Region: 716-864
Classification Level Classification E-value
Superfamily Regulator of G-protein signaling, RGS 2.22e-38
Family Regulator of G-protein signaling, RGS 0.0000822
Further Details:      
 
Domain Number 2 Region: 1047-1147
Classification Level Classification E-value
Superfamily Ubiquitin-like 1.34e-30
Family Ras-binding domain, RBD 0.00097
Further Details:      
 
Domain Number 3 Region: 239-379
Classification Level Classification E-value
Superfamily PH domain-like 2.66e-22
Family Phosphotyrosine-binding domain (PTB) 0.014
Further Details:      
 
Domain Number 4 Region: 16-98
Classification Level Classification E-value
Superfamily PDZ domain-like 9.58e-20
Family PDZ domain 0.0075
Further Details:      
 
Domain Number 5 Region: 993-1061
Classification Level Classification E-value
Superfamily Ubiquitin-like 0.0000000000013
Family Ras-binding domain, RBD 0.056
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) E7EZS3
Sequence length 1545
Comment (tr|E7EZS3|E7EZS3_DANRE) Regulator of G protein-signaling 12b {ECO:0000313|Ensembl:ENSDARP00000111549} KW=Complete proteome; Reference proteome OX=7955 OS=Danio rerio (Zebrafish) (Brachydanio rerio). GN=rgs12 OC=Cyprinidae; Danio.
Sequence
MFRQSEQGRRRVNAQPSARIRGVEVARGRTGYGFTLSGQSPCVLNCILKGSPADYVGLRS
GDQILSVNDINVSKASHEDVVKLIGRCTGVLHLVIAEGSHKNGHVDSCSSDEELEFHDHK
SHWLRPKMDSKTLGINRAERVVAEMQSGGIFNMIFENSSHSSSSSERAVACASASKPRAV
SEPEFPYVSVNTQKSDPNLLTEEEMAKVLNDDSVFVDMFEPQDEFALLQTADSAGILNVG
MIVGYLGSIELASTSANLESDSLQAIRGCMRRLRAEQKVHSLVLLKVMHDCVQLCNDRGA
VLATYPAEKLAFSAVCPDDRRFFGLVTMQATNDHRMYRHGEEEQGLRTSCHVFIVDPELC
HHKIHQGIARRFGFDCTPDPDTGGCLEFPPTSQPLLQFVSVLYRDMGESIEGMRARAFLD
GDLDAQQNNSTSSNSDSGIGNFLPEEKNNRVLLVDLGANPSRHVPTGPWENPMGSFCQGA
IGGLPPPPPPPPISHRNGFRHEQFVDHPQPHPHSHGDPPLLSGRHLNSSSRLDVSGLPSR
SHYSAHGKKAAGASGQRWLPVHVLRDWRQGHSSDQESYAESTDGWSSANCSTLPPPMSKI
PADRYRAAGEIASQPHRLHAQKDEWAKKLFGEKNLREHSQQSNNVRRAKDSEKKGGRFKG
ITMGFPQRSSGRRSFGRSKRLSMARSLDDLESAAVSDGELNSVDLKGCGSDNSLNSNASL
PSVQCHRRHTERRVASWAVCFERLLQDPVGVRYFSEFLKKEFSEENILFWQACEYFSHVP
ETDKKQLSQRAREIYNSFLSSKATTPVNIDSQAQLADDILNAPRPDMFKEQQLQIFNLMK
FDSYTRFLKSYLYQECMLAEVEGRPLPDPYQVPSSPTSKHSTGSDRSNLSTPKKVQDDKK
SKSGRSLNEDSRDEHGDKKKSIFFSWSRNRSFGKGSKKRDLADYSFTGSNGRRESQGSLS
SGASLELATSGSGKNEGEVSRNSMSLSERAVRHCNINLPDGSCCSVPIRPGVSIREVLLG
LCEKLGINLAAVDLFLVGGEKPLVLDQDCMTLCSRDLRLEKRTLFRLDLVPINRSVGLKA
KPTKPVTEVLRPVVAKYGLNLGDLVATISGEKEPLDLGLPISNLDGLRVVLEAGDHVSGK
GKRNKQKLVSSKSHGPPLSTRSQSATGEDKTAGKASAVKTRAQVEKRKQKKLNIDEAEEF
FELISKAQSNRADDQRGLLNKSDLVLPDFLRLDTEADGNNLSSTPISHKTRPRSKENGSA
LSASHQTQSLDSAGEGKAPRRALMPPNSALRNTSSRIPPPFSSSLSPIPHSQMGGSSGIT
DWRSDGGVQALEEEESGMDLTFVAEGDITSPNSSLLHQSPIPLPPSPERSHLLKEDTCQD
SWARSGGLMTKTVVSNRNRFSSGNMKNERRQRDRTSVSKYSHRRAPSAPPPPPPHPPPAP
PSAPPRVRGAGKRSPLHVRGALDVDGIHCGDLGGDNRESEGLERVVGDLKTSKGRMRTGV
YQTSDQAELLPTKKRIDPVAKKSIKPSVKTSSKKSNHSKNNATFV
Download sequence
Identical sequences E7EZS3

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