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Domain assignment for F8W6L0 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  F8W6L0
Domain Number 1 Region: 192-536
Classification Level Classification E-value
Superfamily GTPase activation domain, GAP 2.79e-75
Family p120GAP domain-like 0.0000898
Further Details:      
 
Domain Number 2 Region: 40-168
Classification Level Classification E-value
Superfamily C2 domain (Calcium/lipid-binding domain, CaLB) 1.25e-32
Family Synaptotagmin-like (S variant) 0.0024
Further Details:      
 
Domain Number 3 Region: 494-636
Classification Level Classification E-value
Superfamily PH domain-like 3.01e-32
Family Pleckstrin-homology domain (PH domain) 0.0049
Further Details:      
 
Domain Number 4 Region: 1-56
Classification Level Classification E-value
Superfamily C2 domain (Calcium/lipid-binding domain, CaLB) 0.0000982
Family Synaptotagmin-like (S variant) 0.078
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Molecular Function IC (bits) H-Score
Cellular Component IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) F8W6L0
Sequence length 731
Comment (tr|F8W6L0|F8W6L0_HUMAN) Ras GTPase-activating protein 4B {ECO:0000313|Ensembl:ENSP00000303968} KW=Complete proteome; Reference proteome OX=9606 OS=Homo sapiens (Human). GN=RASA4B OC=Catarrhini; Hominidae; Homo.
Sequence
MDEDALSRDDVIGKVCLTRDTIASHPKGFSGWAHLTEVDPDEEVQGEIHLRLEVWPGARA
CRLRCSVLEARDLAPKDRNGTSDPFVRVRYKGRTRETSIVKKSCYPRWNETFEFELQEGA
MEALCVEAWDWDLVSRNDFLGKVVIDVQRLRVVQQEEGWFRLQPDQSKSRRHDEGNLGSL
QLEVRLRDETVLPSSYYQPLVHLLCHEVKLGMQGPGQLIPLIEETTSTECRQDVATNLLK
LFLGQGLAKDFLDLLFQLELSRTSETNTLFRSNSLASKSVESFLKVAGMQYLHGVLGPII
NKVFEEKKYVELDPSKVEVKDVGCSGLHRPQTEAEVLEQSAQTLRAHLGALLSALSRSVR
ACPAVVRATFRQLFRRVRERFPGAQHENVPFIAVTSFLCLRFFSPAIMSPKLFHLRERHA
DARTSRTLLLLAKAVQNVGNMDTPASRAKEAWMEPLQPTVHQGVAQLKDFITKLVDIEEK
DELDLQRTLSLQAPPVKEGPLFIHRTKGKGPLMSSSFKKLYFSLTTEALSFAKTPSSKKS
ALIKLANIRAAEKVEEKSFGGSHVMQVIYTDDAGRPQTAYLQCKCVNELNQWLSALRKVS
INNTGLLGSYHPGVFRGDKWSCCHQKEKTGQGCDKTRSRVTLQEWNDPLDHDLEAQLIYR
HLLGVEAMLWERHRELSGGAEAGTVPTSPGKVPEDSLARLLRVLQDLREAHSSSPAGSPP
SEPNCLLELQT
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Identical sequences F8W6L0
gi|310118384|ref|XP_003119102.1| gi|310118386|ref|XP_003119101.1| gi|310120065|ref|XP_003118647.1| gi|310120067|ref|XP_003118646.1| ENSP00000303968 ENSP00000303968

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