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Domain assignment for G1NYK2 from Uniprot 2018_03 genome

Domain architecture


Domain assignment details

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Strong hits

Sequence:  G1NYK2
Domain Number 1 Region: 188-391
Classification Level Classification E-value
Superfamily DBL homology domain (DH-domain) 7.33e-51
Family DBL homology domain (DH-domain) 0.000000286
Further Details:      
 
Domain Number 2 Region: 2-225
Classification Level Classification E-value
Superfamily Calponin-homology domain, CH-domain 3.14e-39
Family Calponin-homology domain, CH-domain 0.0057
Further Details:      
 
Domain Number 3 Region: 378-540
Classification Level Classification E-value
Superfamily PH domain-like 6.76e-29
Family Pleckstrin-homology domain (PH domain) 0.0082
Further Details:      
 
Domain Number 4 Region: 637-766
Classification Level Classification E-value
Superfamily SH2 domain 4.04e-27
Family SH2 domain 0.00064
Further Details:      
 
Domain Number 5 Region: 803-873
Classification Level Classification E-value
Superfamily SH3-domain 4.07e-22
Family SH3-domain 0.00081
Further Details:      
 
Domain Number 6 Region: 586-665
Classification Level Classification E-value
Superfamily SH3-domain 0.000000000002
Family SH3-domain 0.00041
Further Details:      
 

Gene Ontology term assignment details

The top 10 most specific Gene Ontology terms for each namespace assigned to this domain architecture as determined by dcGO Predictor

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Cellular Component IC (bits) H-Score
Molecular Function IC (bits) H-Score
Biological Process IC (bits) H-Score

Protein sequence

External link(s) G1NYK2
Sequence length 875
Comment (tr|G1NYK2|G1NYK2_MYOLU) Vav guanine nucleotide exchange factor 3 {ECO:0000313|Ensembl:ENSMLUP00000002497} KW=Complete proteome; Reference proteome OX=59463 OS=Myotis lucifugus (Little brown bat). GN=VAV3 OC=Vespertilionidae; Myotis.
Sequence
MEPWRQCAQWLIHCKVLPANHRVTWDSAQVFDLAQTLRDGVLLCQLLNNLRARSINLKEI
NLRPQMSQFLCLKNIRTFLTACCETFGMRKSELFEAFDLFDVRDFGKVIETLSRLSRTPI
ALATGIRPFPTEESVSDEDIYKALPDLIDETHVEDEEGLYDCVYGEDEGGEVYEDLMKAE
EAQQPKCPENDIRSCCLAEIKQTEEKYTETLESIEKYFMAPLKRFLTAAEFDSVFINIPE
LVKVHRNLMQEIHDSIVNKNDQNLYQIFINYKERLVIYGQYCSAVESAISSLDYISKTKE
DVKLKLEECSKRANNGKFTLRDLLVVPMQRVLKYHLLLQELVKHTTDPTEKANLKLALDA
MKDLAQYVNEVKRDNETLREIRQFQLSIENLNQPVLLFGRPQGDGEIRITTLDKHTKQES
KIFLFFLAVIVCKRKGDNYEMKEIIDLQQYKIANNPTTDKENKKWSYGFYLIHTQGHNGL
EFYCKTKDLKKKWLEQFEMALSNIRPDHADSNFHEFKMHTFSRVTSCKACQMLLRGTFYQ
GYLCFKCGARAHKECLGRVDNCGRVNSAESGTLKAPEKRTNGLRRTSRQVDAGLPKMQVI
KNYAGTPPPAPHAGPPLHIQAGDTVELLRGDAHSLFWQGRNLASGEVGFFPSDAVKPCPC
VPKPVDYSCQPWYAGAMERLQAETELINRPNSTYLVRLRTKESGEYAISIKYNNEAKHIK
IVTRDGLFHIAENRKFKSLMELVEYYKHHSLKEGFRTLDTTLQFPYKEPEPAAGQRGSRV
GSSSPSLFCGFSLVPPPDFSFVPPSSTPFWSVLSPKVLGIAVARYDFCARDMRELSLLKG
DVVKIYTKMSGNGWWRGEANGKVGWFPSTYVEVDE
Download sequence
Identical sequences G1NYK2
ENSMLUP00000002497 ENSMLUP00000002497

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