SUPERFAMILY 1.75 HMM library and genome assignments server

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SUPERFAMILY model 0043147

Seed sequence: 97150 d1r6ha_
Superfamily: 52799 (Phosphotyrosine protein) phosphatases II
Comment: 1.69 all builds
Date built: 2005-09-08
Length: 172
Sequences: 1029
Other models: All models from the (Phosphotyrosine protein) phosphatases II superfamily


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Hydrophobicity, emmission, insertion, deletion and amino acid plots

Graphical representation by Martin Madera (explanation below).





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Plot explanation

The top plot (blue line) is the average hydrophobicity, calculated as the sum over all amino acids of (match emmission probability) * (delta-G surface-buried). The transfer energies in kcal/mol are taken from Table 8, Miller et al, J. Mol. Biol. (1987) 196, 641-56.

The middle plot shows match emmission probabilities. The amino acids in each column are ordered from most hydrophilic (top) to most hydrophobic (bottom). The size of each column is proportional to the difference between the match emmission distribution and the generic background distribution:


The columns are partitioned between amino-acids according to the ratio of their probabilities; only letters larger than a threshold size are shown. The columns are aligned at the bottom of A (alanine).

The bottom plot gives the probability that there is an insertion (light green) or a deletion (red) at that position in the HMM. The dark green curve gives the probability P of an insert-insert transition; assuming there is an insertion at that node, 1/(1-P) gives its expected length.


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