SUPERFAMILY 1.75 HMM library and genome assignments server

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EF-hand superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.


All 104 SUPERFAMILY models representing the EF-hand superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0049061 3992 2008-09-10 d1qx2a_ Calbindin D9K
0035893 2446 2005-09-08 d1cb1a_ Calbindin D9K
0035639 2526 2005-09-08 d1boda_ Calbindin D9K
0039003 2493 2005-09-08 d1ig5a_ Calbindin D9K
0039974 2119 2005-09-08 d1k8ua_ S100 proteins
0048211 6316 2008-09-10 d1mr8a_ S100 proteins
0045680 7376 2008-09-10 d1a03a_ S100 proteins
0036831 1986 2005-09-08 d1e8aa_ S100 proteins
0039372 2336 2005-09-08 d1j55a_ S100 proteins
0040758 2009 2005-09-08 d1m31a_ S100 proteins
0048981 8776 2008-09-10 d1qlsa_ S100 proteins
0042454 463 2005-09-08 d1psra_ S100 proteins
0047730 3881 2008-09-10 d1k2ha_ S100 proteins
0051413 3142 2008-09-10 d1yura1 S100 proteins
0041542 1350 2005-09-08 d1nsha_ S100 proteins
0047425 7162 2008-09-10 d1irja_ S100 proteins
0042847 2447 2005-09-08 d1qlka_ S100 proteins
0045710 5692 2008-09-10 d1a4pa_ S100 proteins
0047873 935 2008-09-10 d1ksoa_ S100 proteins
0043728 88 2005-09-08 d1sraa_ Osteonectin
0043372 1553 2005-09-08 d1rtp1_ Parvalbumin
0046115 3492 2008-09-10 d1cdpa_ Parvalbumin
0049237 3214 2008-09-10 d1rroa_ Parvalbumin
0053359 4345 2008-09-10 d5pala_ Parvalbumin
0045726 3081 2008-09-10 d1a75a_ Parvalbumin
0046010 2988 2008-09-10 d1bu3a_ Parvalbumin
0049189 3343 2008-09-10 d1rjva_ Parvalbumin
0053282 3100 2008-09-10 d2pvba_ Parvalbumin
0048828 1756 2008-09-10 d1pvaa_ Parvalbumin
0036425 2187 2005-09-08 d1dgua_ Calmodulin-like
0037066 2030 2005-09-08 d1el4a_ Calmodulin-like
0041978 3440 2005-09-08 d1oqpa_ Calmodulin-like
0043503 2534 2005-09-08 d1s6ca_ Calmodulin-like
0045442 1279 2005-09-08 d2sasa_ Calmodulin-like
0046181 14392 2008-09-10 d1cmfa_ Calmodulin-like
0048467 5101 2008-09-10 d1nyaa_ Calmodulin-like
0049327 4795 2008-09-10 d1s6ia_ Calmodulin-like
0035873 3362 2005-09-08 d1c7wa_ Calmodulin-like
0038094 2114 2005-09-08 d1ggwa_ Calmodulin-like
0039413 125 2005-09-08 d1j7qa_ Calmodulin-like
0041313 3164 2005-09-08 d1ncxa_ Calmodulin-like
0043104 3130 2005-09-08 d1r2ua_ Calmodulin-like
0044955 1348 2005-09-08 d1wdcb_ Calmodulin-like
0045999 2800 2008-09-10 d1br1b_ Calmodulin-like
0049906 3382 2008-09-10 d1uhna_ Calmodulin-like
0035583 3019 2005-09-08 d1bjfa_ Calmodulin-like
0036594 2726 2005-09-08 d1dtla_ Calmodulin-like
0049421 1327 2008-09-10 d1sl8a_ Calmodulin-like
0052892 10293 2008-09-10 d2ggma1 Calmodulin-like
0037031 1694 2005-09-08 d1ej3a_ Calmodulin-like
0039521 2539 2005-09-08 d1jfja_ Calmodulin-like
0041808 1807 2005-09-08 d1oe9b_ Calmodulin-like
0047571 5422 2008-09-10 d1jf0a_ Calmodulin-like
0048244 4433 2008-09-10 d1mxlc_ Calmodulin-like
0037987 3034 2005-09-08 d1g8ia_ Calmodulin-like
0044062 3196 2005-09-08 d1tn4a_ Calmodulin-like
0048083 7620 2008-09-10 d1m45a_ Calmodulin-like
0053194 3908 2008-09-10 d2mysc_ Calmodulin-like
0035206 3012 2005-09-08 d1auib_ Calmodulin-like
0037250 2825 2005-09-08 d1exra_ Calmodulin-like
0045443 1737 2005-09-08 d2scpa_ Calmodulin-like
0046215 2939 2008-09-10 d1ctaa_ Calmodulin-like
0048602 8666 2008-09-10 d1omra_ Calmodulin-like
0049328 4815 2008-09-10 d1s6ja_ Calmodulin-like
0038096 2829 2005-09-08 d1ggza_ Calmodulin-like
0039467 2559 2005-09-08 d1jbaa_ Calmodulin-like
0043217 2853 2005-09-08 d1rfja_ Calmodulin-like
0044956 2396 2005-09-08 d1wdcc_ Calmodulin-like
0048241 11627 2008-09-10 d1mxea_ Calmodulin-like
0037732 2978 2005-09-08 d1fpwa_ Calmodulin-like
0040528 2711 2005-09-08 d1lkja_ Calmodulin-like
0044028 3200 2005-09-08 d1tiza_ Calmodulin-like
0049489 14145 2008-09-10 d1sw8a_ Calmodulin-like
0053193 3857 2008-09-10 d2mysb_ Calmodulin-like
0047413 1556 2008-09-10 d1iq3a_ Eps15 homology domain (EH domain)
0037597 2133 2005-09-08 d1fi6a_ Eps15 homology domain (EH domain)
0042817 1597 2005-09-08 d1qjta_ Eps15 homology domain (EH domain)
0035795 691 2005-09-08 d1c07a_ Eps15 homology domain (EH domain)
0046726 4898 2008-09-10 d1f8ha_ Eps15 homology domain (EH domain)
0054797 336 2010-05-31 d2zkmx1 EF-hand modules in multidomain proteins
0036977 294 2005-09-08 d1eg3a1 EF-hand modules in multidomain proteins
0045207 38 2005-09-08 d2cbla1 EF-hand modules in multidomain proteins
0050653 2566 2008-09-10 d1wlza1 EF-hand modules in multidomain proteins
0049706 39 2008-09-10 d1tuza_ EF-hand modules in multidomain proteins
0036461 407 2005-09-08 d1djxb1 EF-hand modules in multidomain proteins
0038475 289 2005-09-08 d1h8ba_ EF-hand modules in multidomain proteins
0043674 1076 2005-09-08 d1snla_ EF-hand modules in multidomain proteins
0036978 71 2005-09-08 d1eg3a2 EF-hand modules in multidomain proteins
0047687 3922 2008-09-10 d1juoa_ Penta-EF-hand proteins
0051184 3383 2008-09-10 d1y1xa_ Penta-EF-hand proteins
0038680 2726 2005-09-08 d1hqva_ Penta-EF-hand proteins
0040067 1803 2005-09-08 d1kfus_ Penta-EF-hand proteins
0046706 3731 2008-09-10 d1f4qa_ Penta-EF-hand proteins
0036390 1705 2005-09-08 d1df0a1 Penta-EF-hand proteins
0038125 1611 2005-09-08 d1gjya_ Penta-EF-hand proteins
0043035 1502 2005-09-08 d1qxpa2 Penta-EF-hand proteins
0040064 1535 2005-09-08 d1kful1 Penta-EF-hand proteins
0036627 1765 2005-09-08 d1dvia_ Penta-EF-hand proteins
0047377 4 2008-09-10 d1ij5a_ Cbp40 (plasmodial specific CaII-binding protein LAV1-2)
0038410 2659 2005-09-08 d1h4ba_ Polcalcin
0053255 14366 2008-09-10 d2opoa1 Polcalcin
0047768 14428 2008-09-10 d1k9ua_ Polcalcin
0048820 109 2008-09-10 d1pula1 p25-alpha
0050649 118 2008-09-10 d1wlma1 p25-alpha