SUPERFAMILY 1.75 HMM library and genome assignments server

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Cobalamin (vitamin B12)-dependent enzymes superfamily models

A superfamily is represented by one or more models; usually there is more than one model representing the superfamily. Since each model is built to capture the whole superfamily, they are likely to be overlapping and sometimes are mostly overlapping or even redundant to each other. Also models often do not score their own seed sequence more highly than other sequences in the superfamily, so it is a mistake to think that the model represents the seed sequence.

All models are available for immediate download after obtaining a license by filling in a short online registration form. Licenses are free for academic and commercial purposes.

Plots showing hydrophobicity, match emmission probabilities and insertion/deletion probabilities can be viewed for each model by following the model ID link.

All 6 SUPERFAMILY models representing the Cobalamin (vitamin B12)-dependent enzymes superfamily
Model ID No. of seqs Build date Seed sequence Family of seed
0045650 185 2005-09-08 d7reqa1 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
0053373 602 2008-09-10 d7reqb1 Methylmalonyl-CoA mutase, N-terminal (CoA-binding) domain
0046111 74 2008-09-10 d1ccwb_ Glutamate mutase, large subunit
0047460 79 2008-09-10 d1iwpa_ Diol dehydratase, alpha subunit
0046533 79 2008-09-10 d1eexa_ Diol dehydratase, alpha subunit
0051083 51 2008-09-10 d1xrsa_ D-lysine 5,6-aminomutase alpha subunit, KamD