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Disease Ontology (DO): artery disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   cardiovascular system disease [DOID:1287] <3>(41|53) (41|24|14)
+ 1:   vascular disease [DOID:178] <13>(37|48) (38|22|11)
0:   artery disease [DOID:0050828] <12>(29|34) (31|15|8)
- 1:   cerebrovascular disease [DOID:6713] <12>(2|1) (2|1|2)
- 1:   arteriosclerosis [DOID:2349] <6>(13|14) (13|9|3)
- 1:   coronary artery disease [DOID:3393] <6>(10|11) (12|5|5)
- 1:   hypertension [DOID:10763] <5>(8|12) (9|2|0)
- 1:   aortic disease [DOID:520] <3>(4|5) (4|2|0)
- 1:   renal artery disease [DOID:2388] <2>(0|0) (0|0|0)
- 1:   pulmonary embolism [DOID:9477] <1>(0|0) (0|0|0)
- 1:   Sneddon syndrome [DOID:13096](0|0) (0|0|0)
- 1:   median arcuate ligament syndrome [DOID:9892](0|0) (0|0|0)
- 1:   peripheral artery disease [DOID:0050830](0|0) (0|0|0)
- 1:   splenic artery aneurysm [DOID:14006](0|0) (0|0|0)
- 1:   subclavian artery aneurysm [DOID:342](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Fibrinogen coiled-coil and central regions0Direct
Insulin-like0Direct
Apolipoprotein A-I0Direct
Metalloproteases ("zincins"), catalytic domain0.00000008961Direct
Kringle-like0.00008454Direct
TNF-like0.00008903Direct
YWTD domain0.00009003Direct
Leukotriene A4 hydrolase N-terminal domain0.00009227Direct
Blood coagulation inhibitor (disintegrin)0.0007515Direct
PGBD-like0.00116Inherited
Hemopexin-like domain0.001434Inherited
TSP type-3 repeat0.002706Inherited
Hairpin loop containing domain-like0.002706Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.00443Inherited
Multidrug efflux transporter AcrB transmembrane domain0.005037Inherited
Flavoproteins0.005037Inherited
Riboflavin synthase domain-like0.006925Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.006925Inherited
Troponin coil-coiled subunits0.008727Inherited
Calcium-dependent phosphotriesterase0.008727Inherited
Somatomedin B domain0.008727Inherited
Phospholipase A2, PLA20.008727Inherited
MAPEG domain-like0.008727Inherited
EGF/Laminin0.02338Inherited
Snake toxin-like0.391Inherited
GLA-domain0.4826Inherited
TNF receptor-like0.7184Inherited
TIMP-like0.8985Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Fibrinogen coiled-coil and central regions0Direct
Serum paraoxonase/arylesterase 1, PON10Direct
Insulin-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Apolipoprotein A-I0Direct
Extracellular domain of cell surface receptors0.00001349Direct
Leukotriene A4 hydrolase catalytic domain0.00007841Direct
YWTD domain0.00008658Direct
TNF-like0.0001011Direct
Long-chain cytokines0.0001489Direct
Kringle modules0.0001827Direct
Leukotriene A4 hydrolase N-terminal domain0.0004193Direct
Blood coagulation inhibitor (disintegrin)0.0006899Direct
Platelet-derived growth factor-like0.001071Inherited
MMP N-terminal domain0.001105Inherited
Hemopexin-like domain0.001395Inherited
Tissue inhibitor of metalloproteinases, TIMP0.002192Inherited
Thrombospondin C-terminal domain0.002192Inherited
Cytochrome p450 reductase N-terminal domain-like0.002192Inherited
TSP type-3 repeat0.002192Inherited
Matrix metalloproteases, catalytic domain0.003913Inherited
Short-chain cytokines0.004055Inherited
Somatomedin B domain0.007272Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.007272Inherited
NADPH-cytochrome p450 reductase-like0.007272Inherited
Pentraxin (pentaxin)0.007272Inherited
Interleukin-1 (IL-1)0.008548Inherited
Pancreatic lipase, N-terminal domain0.01591Inherited
Fibronectin type II module0.02292Inherited
EGF-type module0.07266Inherited
Transforming growth factor (TGF)-beta0.3183Inherited
GLA-domain0.4446Inherited
Serpins0.638Inherited
TNF receptor-like0.6807Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Insulin-like0Direct
Fibrinogen coiled-coil and central regions0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Apolipoprotein A-I0Direct
Metalloproteases ("zincins"), catalytic domain0.00000004403Direct
Kringle-like0.00004937Direct
TNF-like0.00005214Direct
YWTD domain0.00005278Direct
Leukotriene A4 hydrolase N-terminal domain0.00005402Direct
Blood coagulation inhibitor (disintegrin)0.0004644Direct
PGBD-like0.0007353Direct
Hemopexin-like domain0.0009141Direct
TSP type-3 repeat0.001777Inherited
Hairpin loop containing domain-like0.001777Inherited
Lipase/lipooxygenase domain (PLAT/LH2 domain)0.002982Inherited
Flavoproteins0.003411Inherited
Multidrug efflux transporter AcrB transmembrane domain0.003411Inherited
Riboflavin synthase domain-like0.004768Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.004768Inherited
Somatomedin B domain0.006007Inherited
Troponin coil-coiled subunits0.006007Inherited
Calcium-dependent phosphotriesterase0.006007Inherited
Phospholipase A2, PLA20.006007Inherited
MAPEG domain-like0.006007Inherited
EGF/Laminin0.01708Inherited
Snake toxin-like0.3378Inherited
FnI-like domain0.3378Inherited
GLA-domain0.4231Inherited
Serpins0.6053Inherited
TNF receptor-like0.6468Inherited
TIMP-like0.8268Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0000001856Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.000008917Direct
    57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00001134Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.00005402Direct
    63737,55486
  • 63737 - Leukotriene A4 hydrolase N-terminal domain
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.00005402Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0.0003154Direct
    53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0.0003154Direct
    55486,57552
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 57552 - Blood coagulation inhibitor (disintegrin)
  • 0.0004644Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0007353Direct
    103647,49899
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.001777Inherited
    103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.001777Inherited
    57184,63825
  • 57184 - Growth factor receptor domain
  • 63825 - YWTD domain
  • 0.006007Inherited
    53474,49723
  • 53474 - alpha/beta-Hydrolases
  • 49723 - Lipase/lipooxygenase domain (PLAT/LH2 domain)
  • 0.006007Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.01028Inherited
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.6916Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57424,57424,57424
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 57424 - LDL receptor-like module
  • 0.00005278Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00005402Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.00005402Direct
    103647,103647,103647
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 0.001777Inherited
    103647,103647,49899
  • 103647 - TSP type-3 repeat
  • 103647 - TSP type-3 repeat
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.001777Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.002778Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.004768Inherited
    57184,57196,57196
  • 57184 - Growth factor receptor domain
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 0.09872Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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