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Disease Ontology (DO): disease of mental health

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   disease [DOID:4] <8>
0:   disease of mental health [DOID:150] <12>(23|30) (24|14|4)
- 1:   personality disorder [DOID:1510] <10>(0|0) (0|0|0)
- 1:   sleep disorder [DOID:535] <7>(0|0) (0|0|0)
- 1:   impulse control disorder [DOID:10937] <6>(0|0) (0|0|0)
- 1:   somatoform disorder [DOID:4737] <6>(0|0) (0|0|0)
- 1:   cognitive disorder [DOID:1561] <5>(19|23) (20|7|2)
- 1:   sexual disorder [DOID:0060043] <5>(0|0) (0|0|0)
- 1:   dissociative disorder [DOID:10935] <3>(0|0) (0|0|0)
- 1:   substance-related disorder [DOID:303] <3>(6|8) (6|5|1)
- 1:   developmental disorder of mental health [DOID:0060037] <2>(8|8) (8|2|0)
- 1:   gender identity disorder [DOID:1234] <2>(0|0) (0|0|0)
- 1:   factitious disorder [DOID:1766] <1>(0|0) (0|0|0)
- 1:   adjustment disorder [DOID:507](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
ACT-like0Direct
GDNF receptor-like0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Synuclein0Direct
p53 tetramerization domain0Direct
Proton glutamate symport protein0Direct
Nicotinic receptor ligand binding domain-like0.00000000000003045Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000000003045Direct
Periplasmic binding protein-like I0.00000000009921Direct
Periplasmic binding protein-like II0.00000000294Direct
Family A G protein-coupled receptor-like0.0000009865Direct
Voltage-gated potassium channels0.000001921Direct
Flavoproteins0.00008798Direct
14-3-3 protein0.001715Inherited
SNF-like0.003876Inherited
Carbohydrate phosphatase0.006585Inherited
Tubulin nucleotide-binding domain-like0.01653Inherited
Tubulin C-terminal domain-like0.01653Inherited
GroES-like0.08816Inherited
4-helical cytokines0.1155Inherited
HLH, helix-loop-helix DNA-binding domain0.1339Inherited
Hormone receptor domain0.3271Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
p53 DNA-binding domain-like0Direct
Synapsin C-terminal domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Synuclein0Direct
Phenylalanine metabolism regulatory domain0Direct
Proton glutamate symport protein0Direct
GDNF receptor-like0Direct
Synapsin domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Neurotransmitter-gated ion-channel transmembrane pore0.00000000000003496Direct
Nicotinic receptor ligand binding domain-like0.00000000000003496Direct
Phosphate binding protein-like0.0000000001345Direct
L-arabinose binding protein-like0.00000000767Direct
Rhodopsin-like0.000003277Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.001232Inherited
Pyridoxal-dependent decarboxylase0.001232Inherited
NADPH-cytochrome p450 reductase-like0.001232Inherited
14-3-3 protein0.001295Inherited
SNF-like0.003133Inherited
Inositol monophosphatase/fructose-1,6-bisphosphatase-like0.005016Inherited
Acetylcholinesterase-like0.01355Inherited
Tubulin, GTPase domain0.01355Inherited
Tubulin, C-terminal domain0.01355Inherited
Alcohol dehydrogenase-like, N-terminal domain0.05436Inherited
Alcohol dehydrogenase-like, C-terminal domain0.05436Inherited
Fatty acid binding protein-like0.1046Inherited
HLH, helix-loop-helix DNA-binding domain0.1326Inherited
Hormone receptor domain0.3074Inherited
Serpins0.5733Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Synuclein0Direct
ACT-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
GDNF receptor-like0Direct
Proton glutamate symport protein0Direct
p53 tetramerization domain0Direct
Aromatic aminoacid monoxygenases, catalytic and oligomerization domains0Direct
Nicotinic receptor ligand binding domain-like0.0000000000000134Direct
Neurotransmitter-gated ion-channel transmembrane pore0.0000000000000134Direct
Periplasmic binding protein-like I0.00000000004562Direct
Periplasmic binding protein-like II0.000000001372Direct
Family A G protein-coupled receptor-like0.0000005064Direct
Voltage-gated potassium channels0.000001008Direct
Flavoproteins0.00005147Direct
14-3-3 protein0.001099Inherited
SNF-like0.0026Inherited
Carbohydrate phosphatase0.004519Inherited
Tubulin C-terminal domain-like0.0118Inherited
Tubulin nucleotide-binding domain-like0.0118Inherited
GroES-like0.06954Inherited
4-helical cytokines0.09224Inherited
HLH, helix-loop-helix DNA-binding domain0.1079Inherited
Hormone receptor domain0.2803Inherited
Serpins0.5592Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57889,49562
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    81324,53850
  • 81324 - Voltage-gated potassium channels
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    53822,53850
  • 53822 - Periplasmic binding protein-like I
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    55021,56534
  • 55021 - ACT-like
  • 56534 - Aromatic aminoacid monoxygenases, catalytic and oligomerization domains
  • 0Direct
    63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.0000000000000134Direct
    49785,49899
  • 49785 - Galactose-binding domain-like
  • 49899 - Concanavalin A-like lectins/glucanases
  • 0.004519Inherited
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.006388Inherited
    51735,50129
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.009867Inherited
    52490,55307
  • 52490 - Tubulin nucleotide-binding domain-like
  • 55307 - Tubulin C-terminal domain-like
  • 0.0118Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.01748Inherited
    50129,51735
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 0.04833Inherited
    111418,81321
  • 111418 - Hormone receptor domain
  • 81321 - Family A G protein-coupled receptor-like
  • 0.235Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57889,57889,49562
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 0Direct
    50129,51735,50129
  • 50129 - GroES-like
  • 51735 - NAD(P)-binding Rossmann-fold domains
  • 50129 - GroES-like
  • 0.009867Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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