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Disease Ontology (DO): kidney disease

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ 1:   urinary system disease [DOID:18] <10>(20|29) (22|11|6)
0:   kidney disease [DOID:557] <24>(19|28) (21|11|6)
- 1:   renal tubular transport disease [DOID:447] <8>(0|0) (0|0|0)
- 1:   impaired renal function disease [DOID:11705] <5>(0|0) (0|0|0)
- 1:   kidney failure [DOID:1074] <3>(4|5) (4|3|1)
- 1:   nephritis [DOID:10952] <2>(8|16) (10|5|3)
- 1:   pyelitis [DOID:2744] <2>(0|0) (0|0|0)
- 1:   renal agenesis [DOID:14766] <2>(0|0) (0|0|0)
- 1:   cystic kidney disease [DOID:2975] <1>(0|0) (0|0|0)
- 1:   nephrosis [DOID:2527] <1>(1|1) (1|0|0)
- 1:   proteinuria [DOID:576] <1>(3|4) (3|1|0)
- 1:   acute urate nephropathy [DOID:580](0|0) (0|0|0)
- 1:   anuria [DOID:2983](0|0) (0|0|0)
- 1:   diabetes insipidus [DOID:9409](0|0) (0|0|0)
- 1:   familial juvenile hyperuricemic nephropathy [DOID:0060062](0|0) (0|0|0)
- 1:   kidney cortex necrosis [DOID:2973](0|0) (0|0|0)
- 1:   kidney hypertrophy [DOID:9622](0|0) (0|0|0)
- 1:   kidney papillary necrosis [DOID:2981](0|0) (0|0|0)
- 1:   nephrocalcinosis [DOID:12679](0|0) (0|0|0)
- 1:   nephrolithiasis [DOID:585](0|0) (0|0|0)
- 1:   orthostatic proteinuria [DOID:9617](0|0) (0|0|0)
- 1:   perinephritis [DOID:2982](0|0) (0|0|0)
- 1:   primary hyperoxaluria [DOID:2977](0|0) (0|0|0)
- 1:   renal fibrosis [DOID:0050855](0|0) (0|0|0)
- 1:   renal infectious disease [DOID:782](0|0) (0|0|0)
- 1:   stricture or kinking of ureter [DOID:3508](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
TNF receptor-like0.0000001163Direct
GLA-domain0.00001583Direct
Kringle-like0.00012Direct
Anaphylotoxins (complement system)0.0003119Direct
Apolipoprotein A-I0.0003119Direct
SMAD MH1 domain0.0003837Direct
Immunoglobulin0.003214Inherited
Complement control module/SCR domain0.003543Inherited
Alpha-macroglobulin receptor domain0.005002Inherited
Flavoproteins0.005002Inherited
C-type lectin-like0.007095Inherited
Heme-dependent peroxidases0.008153Inherited
Terpenoid cyclases/Protein prenyltransferases0.01229Inherited
Serpins0.07815Inherited
Fibronectin type III0.09793Inherited
4-helical cytokines0.7981Inherited
STAT0.9915Inherited
Transcription factor STAT-4 N-domain0.9915Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
TNF receptor-like0.0000002031Direct
Noncollagenous (NC1) domain of collagen IV0.000002146Direct
GLA-domain0.00001302Direct
Netrin-like domain (NTR/C345C module)0.0002352Direct
Cytochrome p450 reductase N-terminal domain-like0.0002352Direct
Apolipoprotein A-I0.0002352Direct
Anaphylotoxins (complement system)0.0002352Direct
SMAD domain0.0002987Direct
SMAD MH1 domain0.0002987Direct
Retinol binding protein-like0.0002987Direct
Interleukin-1 (IL-1)0.000662Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.0008845Direct
NADPH-cytochrome p450 reductase-like0.0008845Direct
C2 set domains0.001239Inherited
Complement control module/SCR domain0.003325Inherited
Alpha-macroglobulin receptor domain0.003991Inherited
Complement components0.003991Inherited
Myeloperoxidase-like0.006579Inherited
Interferons/interleukin-10 (IL-10)0.00915Inherited
Growth factor receptor domain0.0191Inherited
I set domains0.0396Inherited
Serpins0.06332Inherited
Fibronectin type III0.1054Inherited
Transcription factor STAT-4 N-domain0.9819Inherited
STAT DNA-binding domain0.9819Inherited
Long-chain cytokines0.9819Inherited
STAT0.9819Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
TNF receptor-like0.00000005733Direct
GLA-domain0.000008792Direct
Kringle-like0.00007107Direct
Anaphylotoxins (complement system)0.0001886Direct
Apolipoprotein A-I0.0001886Direct
SMAD MH1 domain0.0002336Direct
Immunoglobulin0.002133Inherited
Complement control module/SCR domain0.002369Inherited
Alpha-macroglobulin receptor domain0.003387Inherited
Flavoproteins0.003387Inherited
Cystine-knot cytokines0.003952Inherited
C-type lectin-like0.004895Inherited
Heme-dependent peroxidases0.005594Inherited
Terpenoid cyclases/Protein prenyltransferases0.00865Inherited
Serpins0.06126Inherited
Fibronectin type III0.07769Inherited
4-helical cytokines0.726Inherited
Cytokine0.8805Inherited
STAT0.9242Inherited
Transcription factor STAT-4 N-domain0.9242Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00000005072Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000003073Direct
    57630,57196
  • 57630 - GLA-domain
  • 57196 - EGF/Laminin
  • 0.00008277Direct
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.0001886Direct
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.0002294Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.001661Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.01822Inherited
    48726,49265
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.05115Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.9242Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.9242Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.9242Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000001487Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0005223Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.004232Inherited
    48726,48726,49265
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 49265 - Fibronectin type III
  • 0.2085Inherited
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.9242Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.9242Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)