SUPERFAMILY 1.75 HMM library and genome assignments server

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Disease Ontology (DO): carbohydrate metabolism disease

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of metabolism [DOID:0014667] <2>(22|34) (27|12|5)
+ 1:   acquired metabolic disease [DOID:0060158] <8>(14|21) (16|10|5)
0:   carbohydrate metabolism disease [DOID:0050013] <1>(7|9) (8|5|4)
- 1:   glucose metabolism disease [DOID:4194] <5>(7|9) (8|5|4)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Rudiment single hybrid motif0Direct
Apolipoprotein A-I0Direct
MHC antigen-recognition domain0.08475Inherited
4-helical cytokines0.274Inherited
TNF-like0.5881Inherited
MFS general substrate transporter1Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Multidomain cupredoxins0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
BC C-terminal domain-like0Direct
BC N-terminal domain-like0.0002908Direct
BC ATP-binding domain-like0.0002908Direct
C1 set domains (antibody constant domain-like)0.06292Inherited
MHC antigen-recognition domain0.07391Inherited
TNF-like0.5603Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Apolipoprotein A-I0Direct
Rudiment single hybrid motif0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
MHC antigen-recognition domain0.06661Inherited
Complement control module/SCR domain0.2272Inherited
4-helical cytokines0.2313Inherited
TNF-like0.5221Inherited
MFS general substrate transporter0.9512Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
56059,51246
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    49503,49503
  • 49503 - Cupredoxins
  • 49503 - Cupredoxins
  • 0Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0001114Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.06661Inherited
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.1827Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    52440,56059,51246
  • 52440 - PreATP-grasp domain
  • 56059 - Glutathione synthetase ATP-binding domain-like
  • 51246 - Rudiment single hybrid motif
  • 0Direct
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.001011Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.001011Inherited
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.2622Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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