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Disease Ontology (DO): disease by infectious agent

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ 1:   disease [DOID:4] <8>
0:   disease by infectious agent [DOID:0050117] <4>(37|50) (40|21|10)
- 1:   viral infectious disease [DOID:934] <81>(13|20) (16|9|3)
- 1:   fungal infectious disease [DOID:1564] <4>(4|2) (4|0|0)
- 1:   parasitic infectious disease [DOID:1398] <4>(9|8) (10|0|0)
- 1:   bacterial infectious disease [DOID:104] <3>(14|21) (17|7|1)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
Defensin-like0Direct
p53 tetramerization domain0Direct
Interleukin 8-like chemokines0.00000000006726Direct
4-helical cytokines0.00000001577Direct
DEATH domain0.00000007772Direct
MHC antigen-recognition domain0.0000003932Direct
Toll/Interleukin receptor TIR domain0.0000005699Direct
TNF receptor-like0.000001618Direct
Immunoglobulin0.00002555Direct
Integrin domains0.00004165Direct
SH2 domain0.0001827Direct
SMAD/FHA domain0.0003293Direct
Integrin beta tail domain0.0005741Direct
Heme-dependent peroxidases0.000696Direct
C-type lectin-like0.001067Inherited
Triple coiled coil domain of C-type lectins0.002242Inherited
PGBD-like0.002648Inherited
Bcl-2 inhibitors of programmed cell death0.003228Inherited
Nuclear receptor ligand-binding domain0.003417Inherited
SOCS box-like0.004594Inherited
p53-like transcription factors0.004839Inherited
dsRNA-binding domain-like0.005954Inherited
Hemopexin-like domain0.0142Inherited
STAT0.01809Inherited
Transcription factor STAT-4 N-domain0.01809Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.06625Inherited
Protein kinase-like (PK-like)0.07735Inherited
Flavoproteins0.08311Inherited
SRCR-like0.1327Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.2257Inherited
Riboflavin synthase domain-like0.2257Inherited
ABC transporter transmembrane region0.2888Inherited
Bromodomain0.4214Inherited
Cytokine0.501Inherited
Fibronectin type III0.5928Inherited
L domain-like0.6163Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
p53 tetramerization domain0Direct
C5 cytosine-specific DNA methylase, DCM0Direct
Defensin0Direct
2'-5'-oligoadenylate synthetase 1, OAS1, second domain0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
p53 DNA-binding domain-like0Direct
2'-5'-oligoadenylate synthetase 1, OAS1, N-terminal domain0Direct
Interleukin 8-like chemokines0.0000000001093Direct
Toll/Interleukin receptor TIR domain0.0000001884Direct
MHC antigen-recognition domain0.0000004772Direct
Short-chain cytokines0.0000005973Direct
TNF receptor-like0.0000007239Direct
C1 set domains (antibody constant domain-like)0.000003199Direct
Integrin domains0.00004246Direct
Interferon regulatory factor 3 (IRF3), transactivation domain0.0001138Direct
Histone deacetylase, HDAC0.0001548Direct
Interferon regulatory factor0.0001562Direct
C2 set domains0.0001562Direct
SH2 domain0.0002563Direct
C-type lectin domain0.0004204Direct
Caspase catalytic domain0.0004285Direct
Pyrin domain, PYD0.0004569Direct
Integrin beta tail domain0.0004569Direct
Integrin beta EGF-like domains0.0004569Direct
Myeloperoxidase-like0.0005749Direct
Phoshoinositide 3-kinase (PI3K), catalytic domain0.0009887Direct
Triple coiled coil domain of C-type lectins0.001793Inherited
MMP N-terminal domain0.002424Inherited
Bcl-2 inhibitors of programmed cell death0.002814Inherited
Nuclear receptor ligand-binding domain0.003661Inherited
SOCS box-like0.003964Inherited
Double-stranded RNA-binding domain (dsRBD)0.003964Inherited
Nuclear receptor0.005285Inherited
Cytochrome p450 reductase N-terminal domain-like0.00666Inherited
Interferons/interleukin-10 (IL-10)0.008915Inherited
Matrix metalloproteases, catalytic domain0.009329Inherited
Hemopexin-like domain0.01337Inherited
STAT DNA-binding domain0.01554Inherited
STAT0.01554Inherited
Transcription factor STAT-4 N-domain0.01554Inherited
NADPH-cytochrome p450 reductase FAD-binding domain-like0.02079Inherited
NADPH-cytochrome p450 reductase-like0.02079Inherited
Interleukin-1 (IL-1)0.0292Inherited
I set domains0.04039Inherited
Papain-like0.07282Inherited
ABC transporter transmembrane region0.1551Inherited
Protein kinases, catalytic subunit0.2076Inherited
Bromodomain0.4203Inherited
ABC transporter ATPase domain-like0.4937Inherited
Fibronectin type III0.6443Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
p53 tetramerization domain0Direct
Defensin-like0Direct
Nitric oxide (NO) synthase oxygenase domain0Direct
Interleukin 8-like chemokines0.00000000003082Direct
4-helical cytokines0.000000007429Direct
DEATH domain0.00000003804Direct
MHC antigen-recognition domain0.0000002005Direct
Toll/Interleukin receptor TIR domain0.000000292Direct
TNF receptor-like0.0000008432Direct
Immunoglobulin0.00001448Direct
Integrin domains0.00002387Direct
SH2 domain0.0001085Direct
SMAD/FHA domain0.0001994Direct
Integrin beta tail domain0.0003523Direct
Heme-dependent peroxidases0.0004283Direct
C-type lectin-like0.0006734Direct
Triple coiled coil domain of C-type lectins0.001473Inherited
PGBD-like0.001743Inherited
Bcl-2 inhibitors of programmed cell death0.002144Inherited
Nuclear receptor ligand-binding domain0.002277Inherited
SOCS box-like0.003105Inherited
p53-like transcription factors0.003276Inherited
dsRNA-binding domain-like0.004081Inherited
Hemopexin-like domain0.01007Inherited
RNI-like0.01258Inherited
STAT0.013Inherited
Transcription factor STAT-4 N-domain0.013Inherited
TNF-like0.01466Inherited
Glucocorticoid receptor-like (DNA-binding domain)0.05125Inherited
Protein kinase-like (PK-like)0.06057Inherited
Flavoproteins0.0653Inherited
SRCR-like0.107Inherited
Riboflavin synthase domain-like0.1879Inherited
Ferredoxin reductase-like, C-terminal NADP-linked domain0.1879Inherited
ABC transporter transmembrane region0.2449Inherited
Bromodomain0.366Inherited
Cytokine0.4403Inherited
Cysteine proteinases0.5008Inherited
Fibronectin type III0.5267Inherited
L domain-like0.5489Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0Direct
    63763,57903
  • 63763 - SAND domain-like
  • 57903 - FYVE/PHD zinc finger
  • 0Direct
    54452,48726
  • 54452 - MHC antigen-recognition domain
  • 48726 - Immunoglobulin
  • 0.00000102Direct
    57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.00000142Direct
    47986,47986
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 0.00008223Direct
    55550,158235
  • 55550 - SH2 domain
  • 158235 - SOCS box-like
  • 0.00008223Direct
    54768,54768
  • 54768 - dsRNA-binding domain-like
  • 54768 - dsRNA-binding domain-like
  • 0.0003523Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0003523Direct
    69179,69179
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0009793Direct
    69318,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 0.0009793Direct
    57944,56436
  • 57944 - Triple coiled coil domain of C-type lectins
  • 56436 - C-type lectin-like
  • 0.001473Inherited
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.001743Inherited
    57716,48508
  • 57716 - Glucocorticoid receptor-like (DNA-binding domain)
  • 48508 - Nuclear receptor ligand-binding domain
  • 0.003998Inherited
    48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.004912Inherited
    49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.013Inherited
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.013Inherited
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.013Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.04995Inherited
    56487,50494
  • 56487 - SRCR-like
  • 50494 - Trypsin-like serine proteases
  • 0.09923Inherited
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.2449Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    63763,57903,47370
  • 63763 - SAND domain-like
  • 57903 - FYVE/PHD zinc finger
  • 47370 - Bromodomain
  • 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    57586,57586,57586
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 57586 - TNF receptor-like
  • 0.0000185Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0.0003523Direct
    69318,69179,69179
  • 69318 - Integrin alpha N-terminal domain
  • 69179 - Integrin domains
  • 69179 - Integrin domains
  • 0.0009793Direct
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.013Inherited
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.013Inherited
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.02556Inherited
    48726,48726,48726
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0.1803Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
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