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Disease Ontology (DO): cell type cancer

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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + 3:   disease [DOID:4] <8>
+ + 2:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ 1:   cancer [DOID:162] <2>(115|181) (120|113|54)
0:   cell type cancer [DOID:0050687] <11>(23|40) (25|27|17)
- 1:   carcinoma [DOID:305] <13>(13|26) (15|19|9)
- 1:   germ cell cancer [DOID:2994] <9>(1|1) (1|0|0)
- 1:   mesenchymal cell neoplasm [DOID:3350] <7>(0|0) (0|0|0)
- 1:   melanoma [DOID:1909] <6>(3|3) (3|2|4)
- 1:   malignant glioma [DOID:3070] <5>(7|8) (7|4|3)
- 1:   sarcoma [DOID:1115] <5>(1|2) (1|2|2)
- 1:   malignant mesothelioma [DOID:1790] <4>(0|1) (0|0|0)
- 1:   mixed cell type cancer [DOID:154] <4>(0|0) (0|0|0)
- 1:   malignant hemangioma [DOID:0080189] <1>(0|0) (0|0|0)
- 1:   blastoma [DOID:0070003](0|0) (0|0|0)
- 1:   gangliocytoma [DOID:2426](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Insulin-like0Direct
Di-copper centre-containing domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
Synuclein0Direct
HSP90 C-terminal domain0Direct
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Purine and uridine phosphorylases0Direct
p53 tetramerization domain0Direct
FAS1 domain0Direct
Integrin beta tail domain0Direct
PGBD-like0.0004998Direct
Metalloproteases ("zincins"), catalytic domain0.0005481Direct
Hemopexin-like domain0.00183Inherited
Growth factor receptor domain0.004444Inherited
Bcl-2 inhibitors of programmed cell death0.006546Inherited
Protein kinase-like (PK-like)0.04215Inherited
Caspase-like0.06396Inherited
Intermediate filament protein, coiled coil region0.06978Inherited
Prefoldin0.5469Inherited
Ubiquitin-like0.5555Inherited
Thioredoxin-like0.6005Inherited
Ran binding protein zinc finger-like0.8455Inherited
HMG-box0.9009Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
Purine and uridine phosphorylases0Direct
Hsp90 middle domain0Direct
p53 tetramerization domain0Direct
FAS1 domain0Direct
Gelsolin-like0Direct
Lesion bypass DNA polymerase (Y-family), catalytic domain0Direct
HSP90 C-terminal domain0Direct
Integrin beta tail domain0Direct
Heat shock protein 90, HSP90, N-terminal domain0Direct
Uteroglobin-like0Direct
Insulin-like0Direct
Synuclein0Direct
Transferrin0Direct
Integrin beta EGF-like domains0Direct
Tissue inhibitor of metalloproteinases, TIMP0Direct
DEATH effector domain, DED0Direct
p53 DNA-binding domain-like0Direct
Nuclear receptor coactivator interlocking domain0Direct
Neurotrophin0Direct
L domain0Direct
Retinoblastoma tumor suppressor domains0Direct
PAS domain of steroid receptor coactivator 1A, NCo-A10Direct
S100 proteins0.00005537Direct
MMP N-terminal domain0.0003793Direct
Growth factor receptor domain0.0004214Direct
Matrix metalloproteases, catalytic domain0.0008824Direct
Hemopexin-like domain0.001417Inherited
Ephrin receptor ligand binding domain0.003064Inherited
Bcl-2 inhibitors of programmed cell death0.005064Inherited
Platelet-derived growth factor-like0.02213Inherited
Caspase catalytic domain0.03269Inherited
Hexokinase0.04575Inherited
Intermediate filament protein, coiled coil region0.06599Inherited
Protein kinases, catalytic subunit0.07784Inherited
Phoshoinositide 3-kinase (PI3K), catalytic domain0.1144Inherited
Protein kinase cysteine-rich domain (cys2, phorbol-binding domain)0.1158Inherited
C5 cytosine-specific DNA methylase, DCM0.1596Inherited
Ras-binding domain, RBD0.2432Inherited
Ran binding protein zinc finger-like0.8246Inherited
HMG-box0.8859Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Lesion bypass DNA polymerase (Y-family), little finger domain0Direct
Purine and uridine phosphorylases0Direct
p53 tetramerization domain0Direct
Di-copper centre-containing domain0Direct
Integrin beta tail domain0Direct
Nuclear receptor coactivator interlocking domain0Direct
HSP90 C-terminal domain0Direct
Insulin-like0Direct
FAS1 domain0Direct
Synuclein0Direct
PGBD-like0.0003056Direct
Metalloproteases ("zincins"), catalytic domain0.0003365Direct
Hemopexin-like domain0.00118Inherited
Growth factor receptor domain0.002997Inherited
Bcl-2 inhibitors of programmed cell death0.004487Inherited
Protein kinase-like (PK-like)0.03174Inherited
Caspase-like0.04933Inherited
Intermediate filament protein, coiled coil region0.05416Inherited
Serine protease inhibitors0.1504Inherited
DNA-glycosylase0.1504Inherited
Prefoldin0.4842Inherited
Ubiquitin-like0.4922Inherited
Thioredoxin-like0.5343Inherited
Ran binding protein zinc finger-like0.7733Inherited
HMG-box0.8297Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
53300,69179
  • 53300 - vWA-like
  • 69179 - Integrin domains
  • 0Direct
    55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    57302,57302
  • 57302 - Snake toxin-like
  • 57302 - Snake toxin-like
  • 0Direct
    57196,90193
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    57184,57603
  • 57184 - Growth factor receptor domain
  • 57603 - FnI-like domain
  • 0Direct
    47576,48065
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 0Direct
    90188,53649
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    49417,47719
  • 49417 - p53-like transcription factors
  • 47719 - p53 tetramerization domain
  • 0Direct
    54236,57889
  • 54236 - Ubiquitin-like
  • 57889 - Cysteine-rich domain
  • 0Direct
    56672,100879
  • 56672 - DNA/RNA polymerases
  • 100879 - Lesion bypass DNA polymerase (Y-family), little finger domain
  • 0Direct
    49562,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 0Direct
    57603,82895
  • 57603 - FnI-like domain
  • 82895 - TSP-1 type 1 repeat
  • 0Direct
    57184,49265
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    53850,53850
  • 53850 - Periplasmic binding protein-like II
  • 53850 - Periplasmic binding protein-like II
  • 0Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57362,57362
  • 57362 - BPTI-like
  • 57362 - BPTI-like
  • 0Direct
    82153,82153
  • 82153 - FAS1 domain
  • 82153 - FAS1 domain
  • 0Direct
    57196,69687
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0Direct
    90193,90193
  • 90193 - Notch domain
  • 90193 - Notch domain
  • 0Direct
    57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0003056Direct
    56112,47769
  • 56112 - Protein kinase-like (PK-like)
  • 47769 - SAM/Pointed domain
  • 0.002666Inherited
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.004915Inherited
    49785,57184
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 0.007422Inherited
    46579,64593
  • 46579 - Prefoldin
  • 64593 - Intermediate filament protein, coiled coil region
  • 0.01389Inherited
    47986,52129
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0.02019Inherited

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47576,48065,50729
  • 47576 - Calponin-homology domain, CH-domain
  • 48065 - DBL homology domain (DH-domain)
  • 50729 - PH domain-like
  • 0Direct
    57196,57196,69687
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 69687 - Integrin beta tail domain
  • 0Direct
    57924,57924,57924
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 57924 - Inhibitor of apoptosis (IAP) repeat
  • 0Direct
    57184,52058,57184
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0Direct
    57196,57196,90193
  • 57196 - EGF/Laminin
  • 57196 - EGF/Laminin
  • 90193 - Notch domain
  • 0Direct
    55753,55753,55753
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 55753 - Actin depolymerizing proteins
  • 0Direct
    47986,47986,52129
  • 47986 - DEATH domain
  • 47986 - DEATH domain
  • 52129 - Caspase-like
  • 0Direct
    52058,48726,48726
  • 52058 - L domain-like
  • 48726 - Immunoglobulin
  • 48726 - Immunoglobulin
  • 0Direct
    90188,90188,53649
  • 90188 - Somatomedin B domain
  • 90188 - Somatomedin B domain
  • 53649 - Alkaline phosphatase-like
  • 0Direct
    49562,57889,57889
  • 49562 - C2 domain (Calcium/lipid-binding domain, CaLB)
  • 57889 - Cysteine-rich domain
  • 57889 - Cysteine-rich domain
  • 0Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0Direct
    49785,57184,49265
  • 49785 - Galactose-binding domain-like
  • 57184 - Growth factor receptor domain
  • 49265 - Fibronectin type III
  • 0Direct
    53067,53067,53067
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 53067 - Actin-like ATPase domain
  • 0Direct
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.001571Inherited
    55550,56112,56112
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 56112 - Protein kinase-like (PK-like)
  • 0.1504Inherited
    50729,55550,56112
  • 50729 - PH domain-like
  • 55550 - SH2 domain
  • 56112 - Protein kinase-like (PK-like)
  • 0.1504Inherited
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.5165Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
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