SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Disease Ontology (DO): synucleinopathy

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + 5:   disease [DOID:4] <8>
+ + + + 4:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + 3:   nervous system disease [DOID:863] <11>(51|61) (54|28|13)
+ + 2:   central nervous system disease [DOID:331] <16>(33|44) (36|21|9)
+ 1:   neurodegenerative disease [DOID:1289] <21>(24|31) (26|17|7)
0:   synucleinopathy [DOID:0050890] <3>(4|5) (4|1|0)
- 1:   Parkinson's disease [DOID:14330] <3>(1|2) (1|0|0)
- 1:   multiple system atrophy [DOID:4752] <1>(0|0) (0|0|0)
- 1:   Lewy body dementia [DOID:12217](3|3) (3|1|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Synuclein0Direct
Insulin-like0.000139Direct
Neurotransmitter-gated ion-channel transmembrane pore0.05046Inherited
Nicotinic receptor ligand binding domain-like0.05046Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
Synuclein0Direct
Insulin-like0.000104Direct
Glutathione peroxidase-like0.009399Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.04001Inherited
Nicotinic receptor ligand binding domain-like0.04001Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Synuclein0Direct
Insulin-like0.00008259Direct
Nicotinic receptor ligand binding domain-like0.03834Inherited
Neurotransmitter-gated ion-channel transmembrane pore0.03834Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
63712,90112
  • 63712 - Nicotinic receptor ligand binding domain-like
  • 90112 - Neurotransmitter-gated ion-channel transmembrane pore
  • 0.03834Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)