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Disease Ontology (DO): prostate cancer

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   disease [DOID:4] <8>
+ + + + + 5:   disease of cellular proliferation [DOID:14566] <3>(123|191) (129|118|56)
+ + + + 4:   cancer [DOID:162] <2>(115|181) (120|113|54)
+ + + 3:   organ system cancer [DOID:0050686] <14>(66|106) (72|58|31)
+ + 2:   reproductive organ cancer [DOID:193] <3>(11|14) (12|10|3)
+ 1:   male reproductive organ cancer [DOID:3856] <10>(5|8) (5|7|3)
0:   prostate cancer [DOID:10283] <5>(5|6) (5|6|3)
- 1:   prostate carcinoma [DOID:10286] <6>(1|1) (1|3|2)
- 1:   prostate sarcoma [DOID:4054] <4>(0|0) (0|0|0)
- 1:   prostate lymphoma [DOID:10290](0|0) (0|0|0)
- 1:   prostate malignant phyllodes tumor [DOID:10289](0|0) (0|0|0)
- 1:   prostate neuroendocrine neoplasm [DOID:2992](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
PGBD-like0.0000001571Direct
Hemopexin-like domain0.000001075Direct
Cystine-knot cytokines0.0001575Direct
Metalloproteases ("zincins"), catalytic domain0.0006658Direct
Nucleotide-diphospho-sugar transferases0.04567Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

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SCOP termFDR (all)Annotation (direct or inherited)
MMP N-terminal domain0.0000001245Direct
Matrix metalloproteases, catalytic domain0.0000005567Direct
Hemopexin-like domain0.0000008597Direct
Protein kinases, catalytic subunit0.00001907Direct
L domain0.00008981Direct
Transforming growth factor (TGF)-beta0.0008779Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
PGBD-like0.00000007812Direct
Hemopexin-like domain0.0000005533Direct
Cystine-knot cytokines0.00009432Direct
Metalloproteases ("zincins"), catalytic domain0.0004095Direct
Nucleotide-diphospho-sugar transferases0.0346Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.00000007812Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00002514Direct
    57184,52058
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00007156Direct
    52058,57184
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 0.00007156Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.0004294Direct
    81296,81296
  • 81296 - E set domains
  • 81296 - E set domains
  • 0.0006602Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.00001075Direct
    52058,57184,52058
  • 52058 - L domain-like
  • 57184 - Growth factor receptor domain
  • 52058 - L domain-like
  • 0.00007156Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00007156Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)