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Disease Ontology (DO): leukodystrophy

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + + + 6:   disease [DOID:4] <8>
+ + + + + 5:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + + + 4:   nervous system disease [DOID:863] <11>(51|61) (54|28|13)
+ + + 3:   central nervous system disease [DOID:331] <16>(33|44) (36|21|9)
+ + 2:   brain disease [DOID:936] <30>(14|18) (15|6|1)
+ 1:   cerebral degeneration [DOID:1443] <6>(2|2) (2|3|1)
0:   leukodystrophy [DOID:10579] <7>(2|2) (2|3|1)
- 1:   hypomyelinating leukodystrophy [DOID:0060786] <13>(0|0) (0|0|0)
- 1:   CADASIL [DOID:13945] <2>(0|0) (0|0|0)
- 1:   Alexander disease [DOID:4252](0|0) (0|0|0)
- 1:   Canavan disease [DOID:3613](0|0) (0|0|0)
- 1:   adrenoleukodystrophy [DOID:10588](1|1) (1|1|0)
- 1:   adult-onset autosomal dominant demyelinating leukodystrophy [DOID:0060785](0|0) (0|0|0)
- 1:   leukoencephalopathy with vanishing white matter [DOID:0060868](0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
ABC transporter transmembrane region0.000007813Direct
Kringle-like0.0001472Direct


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Kringle modules0.00002088Direct
ABC transporter ATPase domain-like0.0001004Direct


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
ABC transporter transmembrane region0.000004266Direct
Kringle-like0.00008771Direct

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.000002353Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000002353Direct
    90123,52540
  • 90123 - ABC transporter transmembrane region
  • 52540 - P-loop containing nucleoside triphosphate hydrolases
  • 0.000004266Direct

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    57440,57440,50494
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0000003151Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)