SUPERFAMILY 1.75 HMM library and genome assignments server

Superfamily is undergoing a server migration - you are now browsing on the new server. Please contact us if you experience any problems.

Disease Ontology (DO): tooth disease

(show info)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   gastrointestinal system disease [DOID:77] <14>(33|43) (35|18|5)
+ 1:   mouth disease [DOID:403] <10>(13|13) (14|5|2)
0:   tooth disease [DOID:1091] <9>(12|13) (13|5|2)
- 1:   teeth hard tissue disease [DOID:214] <8>(0|0) (0|0|0)
- 1:   dental pulp disease [DOID:5330] <4>(0|0) (0|0|0)
- 1:   periodontal disease [DOID:3388] <3>(9|10) (10|3|1)
- 1:   anodontia [DOID:13714](0|0) (0|0|0)
- 1:   dental abscess [DOID:0060324](0|0) (0|0|0)
- 1:   dental fluorosis [DOID:13711](0|0) (0|0|0)
- 1:   dentinogenesis imperfecta [DOID:4154](0|0) (0|0|0)
- 1:   periodontosis [DOID:9893](0|0) (0|0|0)
- 1:   tooth agenesis [DOID:0050591](0|0) (0|0|0)


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Superfamily

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
4-helical cytokines0.0000000001526Direct
PGBD-like0.000000001231Direct
Hemopexin-like domain0.00000001313Direct
Anaphylotoxins (complement system)0.000006685Direct
Defensin-like0.000007757Direct
Cytokine0.00002179Direct
Metalloproteases ("zincins"), catalytic domain0.0000392Direct
Kringle-like0.0001219Direct
Alpha-macroglobulin receptor domain0.0001417Direct
TIMP-like0.0002974Direct
Terpenoid cyclases/Protein prenyltransferases0.0004056Direct
RNI-like0.002077Inherited


Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Family

(show details)
SCOP termFDR (all)Annotation (direct or inherited)
MMP N-terminal domain0.0000000009896Direct
Matrix metalloproteases, catalytic domain0.000000006269Direct
Hemopexin-like domain0.00000001053Direct
Short-chain cytokines0.000003942Direct
Netrin-like domain (NTR/C345C module)0.000004686Direct
Anaphylotoxins (complement system)0.000004686Direct
Defensin0.000005731Direct
Interleukin-1 (IL-1)0.000005731Direct
Alpha-macroglobulin receptor domain0.0001062Direct
Complement components0.0001062Direct
Long-chain cytokines0.0006771Direct
Interferons/interleukin-10 (IL-10)0.001628Inherited
Interleukin 8-like chemokines0.002516Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
(show help)

Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

(show details)
Supra-domain (Single) FDR (all) Annotation (direct or inherited)
4-helical cytokines0.00000000007036Direct
PGBD-like0.0000000005729Direct
Hemopexin-like domain0.000000006148Direct
Anaphylotoxins (complement system)0.00000361Direct
Defensin-like0.000004228Direct
Cytokine0.00001223Direct
Metalloproteases ("zincins"), catalytic domain0.00002247Direct
Kringle-like0.00007218Direct
Alpha-macroglobulin receptor domain0.00008421Direct
TIMP-like0.0001803Direct
Terpenoid cyclases/Protein prenyltransferases0.0002477Direct
RNI-like0.001353Inherited
Interleukin 8-like chemokines0.001999Inherited

(show details)
Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
47090,55486
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 0.0000000005729Direct
    55486,50923
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0000004403Direct
    49410,50242
  • 49410 - Alpha-macroglobulin receptor domain
  • 50242 - TIMP-like
  • 0.00000361Direct
    57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.000008724Direct
    57440,50494
  • 57440 - Kringle-like
  • 50494 - Trypsin-like serine proteases
  • 0.0002477Direct

    (show details)
    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47090,55486,50923
  • 47090 - PGBD-like
  • 55486 - Metalloproteases ("zincins"), catalytic domain
  • 50923 - Hemopexin-like domain
  • 0.0000001431Direct
    57440,57440,57440
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 57440 - Kringle-like
  • 0.00004099Direct


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)