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Disease Ontology (DO): nephritis

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Root: DO Hierarchy (disease ontology from University of Maryland)

Shortest distance to current term (+ for parents, - for children) DO term [DO ID] <#Children> (#SF|#FA) #Supra-domain
(Single|Duplex|Triple)
+ + + + 4:   disease [DOID:4] <8>
+ + + 3:   disease of anatomical entity [DOID:7] <12>(143|187) (147|103|58)
+ + 2:   urinary system disease [DOID:18] <10>(20|29) (22|11|6)
+ 1:   kidney disease [DOID:557] <24>(19|28) (21|11|6)
0:   nephritis [DOID:10952] <2>(8|16) (10|5|3)
- 1:   glomerulonephritis [DOID:2921] <18>(5|10) (7|5|3)
- 1:   interstitial nephritis [DOID:1063] <2>(0|0) (0|0|0)


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Superfamily

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SMAD MH1 domain0.00001116Direct
Flavoproteins0.0003573Direct
STAT0.0003573Direct
Transcription factor STAT-4 N-domain0.0003573Direct
Heme-dependent peroxidases0.0006361Direct
Complement control module/SCR domain0.03088Inherited
C-type lectin-like0.04445Inherited


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Family

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SCOP termFDR (all)Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SMAD MH1 domain0.000009426Direct
SMAD domain0.000009426Direct
Cytochrome p450 reductase N-terminal domain-like0.00001427Direct
Interleukin-1 (IL-1)0.00002256Direct
C2 set domains0.00004543Direct
NADPH-cytochrome p450 reductase FAD-binding domain-like0.00005874Direct
NADPH-cytochrome p450 reductase-like0.00005874Direct
STAT DNA-binding domain0.0002944Direct
STAT0.0002944Direct
Transcription factor STAT-4 N-domain0.0002944Direct
Interferons/interleukin-10 (IL-10)0.0004301Direct
Myeloperoxidase-like0.0005235Direct
Complement control module/SCR domain0.02711Inherited
Growth factor receptor domain0.04731Inherited
Noncollagenous (NC1) domain of collagen IV0.04823Inherited


Plot distribution on phylogenetic tree for Superfamily and/or Family domains annotated by this phenotype term
Plot tree as:   Download Newick format tree:
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Jump to [ Top · Phenotype Hierarchy · Superfamily · Family · Supra-domain ]

Supra-domain (including individual superfamily)

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Supra-domain (Single) FDR (all) Annotation (direct or inherited)
Nitric oxide (NO) synthase oxygenase domain0Direct
SMAD MH1 domain0.000006124Direct
STAT0.0002167Direct
Transcription factor STAT-4 N-domain0.0002167Direct
Flavoproteins0.0002167Direct
Heme-dependent peroxidases0.0003908Direct
Complement control module/SCR domain0.02297Inherited
C-type lectin-like0.03356Inherited
Cytokine0.04273Inherited
Cystine-knot cytokines0.1624Inherited

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Supra-domain (Duplex) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
49417,55550
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002167Direct
    48092,47655
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 0.0002167Direct
    47655,49417
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002167Direct
    57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.005925Inherited
    56436,56436
  • 56436 - C-type lectin-like
  • 56436 - C-type lectin-like
  • 0.02211Inherited

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    Supra-domain (Triple) in N- to C-terminal order FDR (all) Annotation (direct or inherited)
    47655,49417,55550
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 55550 - SH2 domain
  • 0.0002167Direct
    48092,47655,49417
  • 48092 - Transcription factor STAT-4 N-domain
  • 47655 - STAT
  • 49417 - p53-like transcription factors
  • 0.0002167Direct
    57535,57535,57535
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 57535 - Complement control module/SCR domain
  • 0.02211Inherited


    Plot distribution on phylogenetic tree for Supra-domains (Single/Individual) annotated by this phenotype term
    Plot tree as:   Download Newick format tree:
    (show help)